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Aliases for ALS2CR11 Gene

Aliases for ALS2CR11 Gene

  • Amyotrophic Lateral Sclerosis 2 (Juvenile) Chromosome Region, Candidate 11 2 3

External Ids for ALS2CR11 Gene

Previous GeneCards Identifiers for ALS2CR11 Gene

  • GC00U990889
  • GC02U900708
  • GC02M202178
  • GC02M202060
  • GC02M202352
  • GC02M194200

Summaries for ALS2CR11 Gene

GeneCards Summary for ALS2CR11 Gene

ALS2CR11 (Amyotrophic Lateral Sclerosis 2 (Juvenile) Chromosome Region, Candidate 11) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ALS2CR11 Gene

Genomics for ALS2CR11 Gene

Regulatory Elements for ALS2CR11 Gene

Genomic Location for ALS2CR11 Gene

201,487,232 bp from pter
201,619,182 bp from pter
131,951 bases
Minus strand

Genomic View for ALS2CR11 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ALS2CR11 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ALS2CR11 Gene

Proteins for ALS2CR11 Gene

  • Protein details for ALS2CR11 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 11 protein
    Protein Accession:
    Secondary Accessions:
    • C9IZH7
    • E9PGG4
    • Q8NCN6
    • Q96LN4

    Protein attributes for ALS2CR11 Gene

    623 amino acids
    Molecular mass:
    71159 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ALS2CR11 Gene


neXtProt entry for ALS2CR11 Gene

Proteomics data for ALS2CR11 Gene at MOPED

Post-translational modifications for ALS2CR11 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ALS2CR11 Gene

Antibody Products

No data available for DME Specific Peptides for ALS2CR11 Gene

Domains for ALS2CR11 Gene

Protein Domains for ALS2CR11 Gene


Suggested Antigen Peptide Sequences for ALS2CR11 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ALS2CR11: view

No data available for Gene Families and UniProtKB/Swiss-Prot for ALS2CR11 Gene

Function for ALS2CR11 Gene

Gene Ontology (GO) - Molecular Function for ALS2CR11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with ALS2CR11: view

Phenotypes for ALS2CR11 Gene

genes like me logo Genes that share phenotypes with ALS2CR11: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ALS2CR11 Gene

Localization for ALS2CR11 Gene

Subcellular locations from

Jensen Localization Image for ALS2CR11 Gene COMPARTMENTS Subcellular localization image for ALS2CR11 gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ALS2CR11 Gene

Pathways for ALS2CR11 Gene

SuperPathways for ALS2CR11 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ALS2CR11 Gene


No data available for Pathways by source for ALS2CR11 Gene

Transcripts for ALS2CR11 Gene

Unigene Clusters for ALS2CR11 Gene

Amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ALS2CR11

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ALS2CR11 Gene

No ASD Table

Relevant External Links for ALS2CR11 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ALS2CR11 Gene

mRNA expression in normal human tissues for ALS2CR11 Gene

mRNA differential expression in normal tissues according to GTEx for ALS2CR11 Gene

This gene is overexpressed in Testis (30.6).

Protein differential expression in normal tissues for ALS2CR11 Gene

This gene is overexpressed in NK cells (69.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ALS2CR11 Gene

SOURCE GeneReport for Unigene cluster for ALS2CR11 Gene Hs.335788

genes like me logo Genes that share expressions with ALS2CR11: view

Expression partners for ALS2CR11 Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ALS2CR11 Gene

Orthologs for ALS2CR11 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ALS2CR11 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ALS2CR11 35
  • 80.55 (n)
  • 65.57 (a)
ALS2CR11 36
  • 61 (a)
(Canis familiaris)
Mammalia LOC609039 35
  • 81.58 (n)
  • 68.11 (a)
-- 36
  • 35 (a)
-- 36
  • 60 (a)
(Mus musculus)
Mammalia LOC102636554 35
  • 73.48 (n)
  • 56.77 (a)
Als2cr11 16
Als2cr11 36
  • 45 (a)
(Pan troglodytes)
Mammalia ALS2CR11 35
  • 99.15 (n)
  • 97.92 (a)
ALS2CR11 36
  • 97 (a)
(Monodelphis domestica)
Mammalia ALS2CR11 36
  • 46 (a)
(Ornithorhynchus anatinus)
Mammalia ALS2CR11 36
  • 56 (a)
Species with no ortholog for ALS2CR11:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ALS2CR11 Gene

Gene Tree for ALS2CR11 (if available)
Gene Tree for ALS2CR11 (if available)

Paralogs for ALS2CR11 Gene

No data available for Paralogs for ALS2CR11 Gene

Variants for ALS2CR11 Gene

Sequence variations from dbSNP and Humsavar for ALS2CR11 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs888013 -- 201,567,158(+) ctttc(C/T)taagt intron-variant
rs888014 -- 201,567,446(+) gaagt(C/G)ccaag intron-variant
rs888015 -- 201,567,593(+) gagct(A/G)atgtt intron-variant
rs959995 -- 201,491,258(+) TGGTA(C/G)TATCC intron-variant, reference, missense
rs963555 -- 201,549,832(+) TTACT(C/T)GCTAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ALS2CR11 Gene

Variant ID Type Subtype PubMed ID
nsv3111 CNV Insertion 18451855
esv24012 CNV Loss 19812545
esv2658936 CNV Deletion 23128226
nsv507063 CNV Insertion 20534489

Relevant External Links for ALS2CR11 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ALS2CR11 Gene

Disorders for ALS2CR11 Gene

No disorders were found for ALS2CR11 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for ALS2CR11 Gene

Publications for ALS2CR11 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3 4
  4. A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2. (PMID: 11586298) Hadano S. … Ikeda J.-E. (Nat. Genet. 2001) 2 3
  5. Gene expression profile of human bone marrow stromal cells: high-throughput expressed sequence tag sequencing analysis. (PMID: 11827452) Jia L. … Francomano C.A. (Genomics 2002) 3

Products for ALS2CR11 Gene

Sources for ALS2CR11 Gene

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