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ALS2CL Gene

protein-coding   GIFtS: 50
GCID: GC03M046685

ALS2 C-Terminal Like

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
ALS2 C-Terminal Like1 2
RN490182
ALS2 C-Terminal-Like Protein2

External Ids:    HGNC: 206051   Entrez Gene: 2591732   Ensembl: ENSG000001780387   OMIM: 6124025   UniProtKB: Q60I273   

Export aliases for ALS2CL gene to outside databases

Previous GC identifer: GC00U900924


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ALS2CL Gene:
ALS2CL (ALS2 C-terminal like) is a protein-coding gene. Diseases associated with ALS2CL include blepharitis, and breast and colorectal cancer. GO annotations related to this gene include Rho guanyl-nucleotide exchange factor activity and identical protein binding. An important paralog of this gene is RSPH10B2.

UniProtKB/Swiss-Prot: AL2CL_HUMAN, Q60I27
Function: Acts as a guanine nucleotide exchange factor (GEF) for Rab5 GTPase. Regulates the ALS2-mediated endosome
dynamics




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000003.12  NT_022517.19  NC_018914.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ALS2CL gene promoter:
         Max1   Elk-1   NF-1   COMP1   c-Myc   c-Ets-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidALS2CL promoter sequence
   Search Chromatin IP Primers for ALS2CL

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ALS2CL


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p21.31   Ensembl cytogenetic band:  3p21.31   HGNC cytogenetic band: 3p21.31

ALS2CL Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ALS2CL gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M046685:  view genomic region     (about GC identifiers)

Start:
46,710,485 bp from pter      End:
46,735,194 bp from pter
Size:
24,710 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: AL2CL_HUMAN, Q60I27 (See protein sequence)
Recommended Name: ALS2 C-terminal-like protein  
Size: 953 amino acids; 107748 Da
Subunit: Homodimer. Forms a heteromeric complex with ALS2 (By similarity). Interacts with ALS2 and RAB5A
Sequence caution: Sequence=BAD18450.1; Type=Frameshift; Positions=878;
Secondary accessions: Q32MA1 Q6AI56 Q6ZNC5 Q6ZNC7 Q6ZTL4 Q86YD2 Q8N9U1 Q8NAL7
Alternative splicing: 6 isoforms:  Q60I27-1   Q60I27-2   Q60I27-3   Q60I27-4   Q60I27-5   Q60I27-6   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ALS2CL: NX_Q60I27

Explore proteomics data for ALS2CL at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ALS2CL Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001177636.1  NP_667340.2  NP_877576.1  

    ENSEMBL proteins: 
     ENSP00000313670   ENSP00000405335   ENSP00000413223   ENSP00000373248   ENSP00000416575  
     ENSP00000395663   ENSP00000395749  

    ALS2CL Human Recombinant Protein Products:

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    Cloud-Clone Corp. CLIAs for ALS2CL


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR000219 DH-domain
     IPR003123 VPS9
     IPR003409 MORN

    Graphical View of Domain Structure for InterPro Entry Q60I27

    ProtoNet protein and cluster: Q60I27

    UniProtKB/Swiss-Prot: AL2CL_HUMAN, Q60I27
    Similarity: Contains 8 MORN repeats
    Similarity: Contains 1 VPS9 domain


    ALS2CL for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: AL2CL_HUMAN, Q60I27
    Function: Acts as a guanine nucleotide exchange factor (GEF) for Rab5 GTPase. Regulates the ALS2-mediated endosome
    dynamics

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005089Rho guanyl-nucleotide exchange factor activity IEA--
    GO:0005096GTPase activator activity IEA--
    GO:0005515protein binding ----
    GO:0017137Rab GTPase binding IEA--
    GO:0042802identical protein binding IPI17239822
         
    ALS2CL for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for ALS2CL:
     Decreased nuclei size in G2M 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ALS2CL
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    1 qRT-PCR Assays for microRNA that regulate ALS2CL:
    hsa-miR-491-5p
    SwitchGear 3'UTR luciferase reporter plasmidALS2CL 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ALS2CL


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    AL2CL_HUMAN, Q60I27: Cytoplasm. Note=Distributed onto the vesicular compartments in the cytoplasm with strong
    punctated staining. Colocalizes with RAB5A onto the vesicular/membranous compartments in the cytoplasm,
    particularly to the leading edges of the cells
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    endosome2
    nucleus2
    extracellular1
    mitochondrion1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016023cytoplasmic membrane-bounded vesicle IEA--

    ALS2CL for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ALS2CL
    Interactions:

        Search GeneGlobe Interaction Network for ALS2CL

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for ALS2CL (Q60I273 ENSP000003136704) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RAB5AP203393, ENSP000002730474I2D: score=2 STRING: ENSP00000273047
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007032endosome organization IGI17239822
    GO:0008104protein localization IEA--
    GO:0035023regulation of Rho protein signal transduction ----

    ALS2CL for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ALS2CL (AL2CL)

    3 HMDB Compounds for ALS2CL    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine diphosphate5'-GDP (see all 10)146-91-8--
    Guanosine monophosphate5'-GMP (see all 14)85-32-5--
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for ALS2CL gene (3 alternative transcripts): 
    NM_001190707.1  NM_147129.3  NM_182775.2  

    Unigene Cluster for ALS2CL:

    ALS2 C-terminal like
    Hs.517937  [show with all ESTs]
    Unigene Representative Sequence: CR627258
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000486301(uc003cpx.2 uc003cpy.2) ENST00000318962(uc003cpz.2 uc003cqa.2 uc003cqc.2 uc003cqb.2)
    ENST00000434140 ENST00000415953 ENST00000383742 ENST00000431015 ENST00000450172
    ENST00000423707 ENST00000498817 ENST00000473484
    miRNA
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    Block miRNA regulation of human, mouse, rat ALS2CL using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate ALS2CL:
    hsa-miR-491-5p
    SwitchGear 3'UTR luciferase reporter plasmidALS2CL 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for ALS2CL
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ALS2CL
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      QuantiTect SYBR Green Assays in human, mouse, rat ALS2CL
      QuantiFast Probe-based Assays in human, mouse, rat ALS2CL

    Additional mRNA sequence: 

    AB107015.1 AK074118.1 AK092455.1 AK093844.1 AK097225.1 AK131270.1 AK131273.1 AL832132.1 
    BC042906.1 BC061883.1 BC075825.1 BC109233.1 CR627258.1 NR_033815.1 

    15 DOTS entries:

    DT.100025982  DT.100757908  DT.100025981  DT.100025983  DT.100820858  DT.95286174  DT.95138296  DT.100820865 
    DT.95319784  DT.97780604  DT.100708557  DT.100801526  DT.120655719  DT.40287752  DT.99930587 

    Selected AceView cDNA sequences (see all 100):

    BI061592 AX747555 BM666636 BX386066 AK093844 AI225005 CB306746 NM_147129 
    BU685010 AK126505 AK131270 AA151264 AA557247 NM_182774 NM_182775 AK092455 
    BQ926546 BQ045190 AX748334 CB127478 BU684640 BU541865 BQ447793 AK131273 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ALS2CL (see all 13)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19a · 19b ^
    SP1:                    -                                               -                                                                       -     -         
    SP2:                    -                                               -                                                                       -     -         
    SP3:                                                                    -                                                                       -     -         
    SP4:                    -                                               -                                                                       -     -         
    SP5:                                                                    -                                                                       -     -         

    ExUns: 20 ^ 21 ^ 22a · 22b ^ 23a · 23b ^ 24 ^ 25 ^ 26a · 26b ^ 27a · 27b ^ 28a · 28b · 28c · 28d · 28e · 28f
    SP1:                                                              -                                             
    SP2:              -                                               -                                             
    SP3:              -                                               -                                             
    SP4:                                                              -                                             
    SP5:                                                              -                                             


    ECgene alternative splicing isoforms for ALS2CL

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ALS2CL expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CGATGCTGAC
    ALS2CL Expression
    About this image

    ALS2CL Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ALS2CL Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.517937

    UniProtKB/Swiss-Prot: AL2CL_HUMAN, Q60I27
    Tissue specificity: Expressed in heart and kidney

        Custom PCR Arrays for ALS2CL
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ALS2CL

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ALS2CL gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Als2cl1 , 5 ALS2 C-terminal like1, 5 82.63(n)1
    81.62(a)1
      9 (60.79 cM)5
    2356331  NM_146228.41  NP_666340.31 
     1108798705 
    chicken
    (Gallus gallus)
    Aves ALS2CL1 ALS2 C-terminal like 61.74(n)
    55.95(a)
      428401  XM_003640647.2  XP_003640695.2 
    lizard
    (Anolis carolinensis)
    Reptilia ALS2CL6
    ALS2 C-terminal like
    53(a)
    1 ↔ 1
    GL343449.1(364842-425949)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia als2cl1 ALS2 C-terminal like 58.29(n)
    52.77(a)
      100492185  XM_002939366.2  XP_002939412.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG71586
    --
    15(a)
    1 → many
    3L(21667494-21672855)


    ENSEMBL Gene Tree for ALS2CL (if available)
    TreeFam Gene Tree for ALS2CL (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ALS2CL gene
    RSPH10B22  RSPH10B2  MORN12  ALS22  RSPH12  MORN32  
    3 SIMAP similar genes for ALS2CL using alignment to 5 protein entries:     AL2CL_HUMAN (see all proteins):
    FLJ00189    MORN4    ALS2

    ALS2CL for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ALS2CL (see all 800)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0377934
    A breast cancer sample4--see VAR_0377932 L F mis40--------
    VAR_0377924
    A breast cancer sample4--see VAR_0377922 Q E mis40--------
    rs1449782411,2
    Cuntested146729610(+) TACACA/GGTCAG 5 R C mis10--------
    rs1427596501,2
    --46710002(+) TGGGCC/TGTGTC 4 -- ds50010--------
    rs1472542591,2
    --46710024(+) CTCTCC/TACTCT 4 -- ds50010--------
    rs754638861,2
    C--46710051(+) AAGTGC/TCATTT 4 -- ds50010--------
    rs9394131,2
    C,F,H--46710098(+) TCACCG/ACTGAA 4 -- ds500128Minor allele frequency- A:0.08NA NS EA WA CSA 2210
    rs9394151,2
    C,H--46710162(+) GAGCTG/AGGCCC 4 -- ds500115Minor allele frequency- A:0.03MN NS EA NA WA CSA 854
    rs1410006761,2
    --46710173(+) TGCCAA/GGCTGC 4 -- ds50010--------
    rs1449723451,2
    --46710274(+) GCCAGA/GGGCTC 4 -- ds50010--------

    HapMap Linkage Disequilibrium report for ALS2CL (46710485 - 46735194 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for ALS2CL:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv876743CNV Loss21882294
    dgv5128n71CNV Loss21882294
    nsv428417CNV Loss18775914
    nsv516623CNV Loss19592680
    nsv10268CNV Gain18304495
    dgv5127n71CNV Gain21882294
    dgv1455e1CNV Complex17122850

    Human Gene Mutation Database (HGMD): ALS2CL
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ALS2CL
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 612402    OMIM disorders: --

    5 diseases for ALS2CL:    
    About MalaCards
    blepharitis    breast and colorectal cancer    squamous cell carcinoma    schizophrenia
    colorectal cancer

    1 disease from the University of Copenhagen DISEASES database for ALS2CL:
    Blepharitis

    ALS2CL for disorders           About GeneDecksing

    Genetic Association Database (GAD): ALS2CL

    Export disorders for ALS2CL gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ALS2CL gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with ALS2CL)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. ALS2CL, a novel ALS2-interactor, modulates ALS2-mediated endosome dynamics. (PubMed id 17239822)1, 2, 3 Suzuki-Utsunomiya K.... Ikeda J.-E. (Biochem. Biophys. Res. Commun. 2007)
    2. ALS2CL, the novel protein highly homologous to the carboxy-terminal half of ALS2, binds to Rab5 and modulates endosome dynamics. (PubMed id 15388334)1, 2, 3 Hadano S.... Ikeda J.-E. (FEBS Lett. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1, 3 Bonaldo M.F.... Soares M.B. (Genome Res. 1996)
    5. Investigation of rare variants in LRP1, KPNA1, ALS2CL and ZNF480 genes in schizophrenia patients reflects genetic heterogeneity of the disease. (PubMed id 23425335)1 Jouan L....Rouleau G.A. (Behav Brain Funct 2013)
    6. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    7. Multiple tumor-suppressor genes on chromosome 3p contribute to head and neck squamous cell carcinoma tumorigenesis. (PubMed id 20657180)1 Lee D.J....Su G.H. (amp 2010)
    8. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    9. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (Science 2006)
    10. The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)2 Muzny D.M....Gibbs R.A. (Nature 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 259173 HGNC: 20605 AceView: ALS2CL Ensembl:ENSG00000178038 euGenes: HUgn259173
    ECgene: ALS2CL H-InvDB: ALS2CL

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for ALS2CL Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ALS2CL gene:
    Search GeneIP for patents involving ALS2CL

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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