Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ALPK3 Gene

protein-coding   GIFtS: 45
GCID: GC15P085359

Alpha-Kinase 3

  Search for ALPK3
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Alpha-Kinase 31 2     MIDORI2
Muscle Alpha-Kinase1 2     Alpha-Protein Kinase 32
Myocyte Induction Differentiation Originator1 2     EC 2.7.11.-3
Muscle Alpha-Protein Kinase2 3     KIAA13303
MAK2 3     

External Ids:    HGNC: 175741   Entrez Gene: 575382   Ensembl: ENSG000001363837   UniProtKB: Q96L963   

Export aliases for ALPK3 gene to outside databases

Previous GC identifers: GC15P083161 GC15P061446


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ALPK3 Gene: 
ALPK3 (alpha-kinase 3) is a protein-coding gene. GO annotations related to this gene include protein serine/threonine kinase activity and ATP binding. An important paralog of this gene is ALPK2.

UniProtKB/Swiss-Prot: ALPK3_HUMAN, Q96L96
Function: Kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical
conformation. Plays a role in cardiomyocyte differentiation (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000015.9  NC_018926.2  NT_010274.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ALPK3 gene promoter:
         HOXA9B   HOXA9   Sp1   Pax-2   CUTL1   Meis-1b   Evi-1   RORalpha1   Zic3   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidALPK3 promoter sequence
   Search SABiosciences Chromatin IP Primers for ALPK3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ALPK3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q25.2   Ensembl cytogenetic band:  15q25.3   HGNC cytogenetic band: 15q25.2

ALPK3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ALPK3 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15P085359:  view genomic region     (about GC identifiers)

Start:
85,359,911 bp from pter      End:
85,416,713 bp from pter
Size:
56,803 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ALPK3_HUMAN, Q96L96 (See protein sequence)
Recommended Name: Alpha-protein kinase 3  
Size: 1907 amino acids; 201272 Da
Subcellular location: Nucleus (By similarity)
Secondary accessions: Q9P2L6

Explore the universe of human proteins at neXtProt for ALPK3: NX_Q96L96

Explore proteomics data for ALPK3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96L96

  • ALPK3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ALPK3 Protein Expression
    REFSEQ proteins: NP_065829.3  
    ENSEMBL proteins: 
     ENSP00000258888  

    Human Recombinant Protein Products for ALPK3: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for ALPK3
    GenScript Custom Purified and Recombinant Proteins Services for ALPK3
    Novus Biologicals ALPK3 Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ISS--

    ALPK3 for ontologies           About GeneDecksing



    ALPK3 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for ALPK3
    GenScript Custom Superior Antibodies Services for ALPK3
    Novus Biologicals ALPK3 Antibodies
    Abcam antibodies for ALPK3
    Browse Antibodies at Cloud-Clone Corp. 
    Search ThermoFisher Antibodies for ALPK3
    LSBio Antibodies in human, mouse, rat for ALPK3 

    Assay Products for ALPK3: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for ALPK3
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ALPK3
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp. 
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ISET: Immunoglobulin superfamily / I-set domain containing
    IGD: Immunoglobulin superfamily / Immunoglobulin-like domain containing

    IUPHAR Guide to PHARMACOLOGY protein family classification: alpha-kinase 3 
    Other alpha kinase family kinases

    5/6 InterPro protein domains (see all 6):
     IPR003598 Ig_sub2
     IPR007110 Ig-like_dom
     IPR013098 Ig_I-set
     IPR011009 Kinase-like_dom
     IPR013783 Ig-like_fold

    Graphical View of Domain Structure for InterPro Entry Q96L96

    ProtoNet protein and cluster: Q96L96

    2 Blocks protein domains:
    IPB003598 Immunoglobulin C-2 type
    IPB013098 Immunoglobulin I-set


    UniProtKB/Swiss-Prot: ALPK3_HUMAN, Q96L96
    Similarity: Belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily
    Similarity: Contains 1 alpha-type protein kinase domain
    Similarity: Contains 2 Ig-like (immunoglobulin-like) domains


    ALPK3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ALPK3_HUMAN, Q96L96
    Function: Kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical
    conformation. Plays a role in cardiomyocyte differentiation (By similarity)

         Enzyme Number (IUBMB): EC 2.7.11.-1

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004674protein serine/threonine kinase activity IEA--
    GO:0005515protein binding ----
    GO:0005524ATP binding IEA--
    GO:0016772transferase activity, transferring phosphorus-containing groups ----
         
    ALPK3 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for ALPK3:
     Decreased substrate adherent c 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ALPK3 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ALPK3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ALPK3 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ALPK3 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ALPK3
    8/67 QIAGEN miScript miRNA Assays for microRNAs that regulate ALPK3 (see all 67):
    hsa-miR-3678-3p hsa-miR-30d hsa-miR-4267 hsa-miR-877* hsa-miR-30a hsa-miR-3622b-3p hsa-miR-4326 hsa-miR-92b
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ALPK3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ALPK3

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ALPK3
    Sirion Biotech Customized adenovirus for overexpression of ALPK3

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for ALPK3 (see all 5)
    OriGene ORF clones in mouse, rat for ALPK3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ALPK3 (NM_020778)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ALPK3
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ALPK3

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ALPK3
    Search LifeMap BioReagents cell lines for ALPK3
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ALPK3


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ALPK3

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for ALPK3 (Q96L963 ENSP000002588884) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006468protein phosphorylation ----
    GO:0007507heart development ISS--

    ALPK3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ALPK3

    Search CenterWatch for drugs/clinical trials and news about ALPK3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ALPK3 gene: 
    NM_020778.4  

    Unigene Cluster for ALPK3:

    Alpha-kinase 3
    Hs.459183  [show with all ESTs]
    Unigene Representative Sequence: NM_020778
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000258888(uc002ble.3 uc010upc.2) ENST00000558077
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ALPK3
    8/67 QIAGEN miScript miRNA Assays for microRNAs that regulate ALPK3 (see all 67):
    hsa-miR-3678-3p hsa-miR-30d hsa-miR-4267 hsa-miR-877* hsa-miR-30a hsa-miR-3622b-3p hsa-miR-4326 hsa-miR-92b
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ALPK3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ALPK3
    Clone
    Products:
         
    OriGene clones in human, mouse for ALPK3 (see all 5)
    OriGene ORF clones in mouse, rat for ALPK3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ALPK3 (NM_020778)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ALPK3
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ALPK3
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for ALPK3
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ALPK3
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ALPK3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ALPK3

    Additional mRNA sequence: 

    AB037751.1 AK022943.1 AK024829.1 AK026851.1 AK300484.1 AL109725.1 AL109780.1 AL365516.1 
    AL832372.1 AL833276.1 AL833288.1 AY044449.1 BC016870.1 BC040192.1 BC067284.1 

    5 DOTS entries:

    DT.40111744  DT.444015  DT.100748218  DT.95269116  DT.75186144 

    24/91 AceView cDNA sequences (see all 91):

    BQ003482 BM127139 AK024829 AA969805 AL832372 AI468778 AB037751 CD365087 
    F28326 BU739292 AA878780 CK903393 AA808727 BM511791 AA969524 AA629186 
    AL109725 AL691555 BF002508 AA972627 AL833276 AI000726 AA999725 AL600754 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ALPK3 expression in normal human tissues (normalized intensities)      ALPK3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGCCAACATT
    ALPK3 Expression
    About this image


    ALPK3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/35 selected tissues (see all 35) fully expand
     
     Epithelium
             vagina ; squamous epithelial cells   
     
     Uterus
             uterus, post-menopause ; glandular cells   
     
     Testis (Reproductive System)    fully expand to see all 4 entries
             Leydig Cells Testis Interstitium
             seminal vesicle ; glandular cells   
     
     Colon (Gastrointestinal Tract)    fully expand to see all 4 entries
             colon ; peripheral nerve/ganglion   
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex

    See ALPK3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ALPK3

    SOURCE GeneReport for Unigene cluster: Hs.459183
        SABiosciences Custom PCR Arrays for ALPK3
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for ALPK3
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ALPK3
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ALPK3
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ALPK3
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ALPK3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for ALPK3 gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Alpk31 , 5 alpha-kinase 31, 5 79.24(n)1
    74.65(a)1
      7 (45.71 cM)5
    1169041  NM_054085.21  NP_473426.21 
     810576005 
    chicken
    (Gallus gallus)
    Aves ALPK36
    alpha-kinase 3
    40(a)
    1 ↔ 1
    10(390101-419904)
    lizard
    (Anolis carolinensis)
    Reptilia ALPK36
    Uncharacterized protein
    39(a)
    1 ↔ 1
    GL343490.1(126977-167284)
    zebrafish
    (Danio rerio)
    Actinopterygii alpk3a6
    BX001033.26
    Uncharacterized protein
    25(a)
    20(a)
    many → 1
    many → 1
    18(26664154-26697514)
    7(31446923-31463503)


    ENSEMBL Gene Tree for ALPK3 (if available)
    TreeFam Gene Tree for ALPK3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ALPK3 gene
    ALPK22  

    ALPK3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1308 SNPs in ALPK3 are shown (see all 1308)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0415264
    A lung large cell carcinoma sample4--see VAR_0415262 Q E mis40--------
    VAR_0415314
    A metastatic melanoma sample4--see VAR_0415312 G E mis40--------
    VAR_0415294
    ----see VAR_0415292 R L mis40--------
    VAR_0415304
    ----see VAR_0415302 E D mis40--------
    rs1445592171,2
    C--85357928(+) AGACTC/TTGATG 1 -- us2k10--------
    rs1424726511,2
    C--85357997(+) TTTGG-/CTGT  
            
    CTGTC
    1 -- us2k10--------
    rs1484694901,2
    --85358006(+) CTGTCA/GGGGAA 1 -- us2k10--------
    rs1858542761,2
    --85358055(+) GGTGCA/GAATTT 1 -- us2k10--------
    rs1901805851,2
    --85358435(+) TCCTTA/GTAAAA 1 -- us2k10--------
    rs1831234261,2
    --85358487(+) CTTTGC/GTGCTT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ALPK3 (85359911 - 85416713 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for ALPK3:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2672879CNV Deletion23128226
    nsv524050CNV Loss19592680
    dgv322n27CNV Gain19166990
    nsv471257CNV Gain18288195
    dgv770e1CNV Complex17122850

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing ALPK3
    DNA2.0 Custom Variant and Variant Library Synthesis for ALPK3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    ALPK3 for disorders           About MalaCards

    ALPK3 for disorders           About GeneDecksing

    Genetic Association Database (GAD): ALPK3

    Export disorders for ALPK3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ALPK3 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with ALPK3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Alpha-kinases: a new class of protein kinases with a novel catalytic domain. (PubMed id 10021370)1, 2, 3 Ryazanov A.G.... Dorovkov M.V. (1999)
    2. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10718198)1, 2 Nagase T.... Ohara O. (2000)
    3. Genome-wide association analysis of age-at-onset in Al zheimer's disease. (PubMed id 22005931)1 Kamboh M.I....Lopez O.L. (2012)
    4. Patterns of somatic mutation in human cancer genomes. (PubMed id 17344846)2 Greenman C.... Stratton M.R. (2007)
    5. Analysis of the DNA sequence and duplication history of human chromosome 15. (PubMed id 16572171)2 Zody M.C....Nusbaum C. (2006)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    8. A novel myocyte-specific gene Midori promotes the differentiation of P19CL6 cells into cardiomyocytes. (PubMed id 11418590)1 Hosoda T....Komuro I. (2001)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 57538 HGNC: 17574 AceView: MIDORI Ensembl:ENSG00000136383 euGenes: HUgn57538
    ECgene: ALPK3 H-InvDB: ALPK3

    (According to HUGE)
    About This Section
    HUGE: KIAA1330

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ALPK3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ALPK3 gene:
    Search GeneIP for patents involving ALPK3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for ALPK3  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for ALPK3  
     OriGene qSTAR qPCR primer pairs in human, mouse for ALPK3   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for ALPK3   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ALPK3   OriGene Custom Protein Services for ALPK3  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ALPK3
     QIAGEN SeqTarget long-range PCR primers for resequencing ALPK3
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ALPK3
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ALPK3
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ALPK3
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ALPK3
     GenScript Custom Purified and Recombinant Proteins Services for ALPK3 GenScript cDNA clones with any tag delivered in your preferred vector for ALPK3
     GenScript Custom Assay Services for ALPK3 GenScript Custom Superior Antibodies Services for ALPK3
     GenScript Custom overexpressing Cell Line Services for ALPK3 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in ALPK3 promoter
     Search Chromatin IP Primers for ALPK3
     RT2 qPCR Primer Assay in human, mouse, rat ALPK3
     Search GNC Networks for ALPK3
     SABiosciences Custom PCR Arrays for ALPK3
     Search Tocris compounds for ALPK3
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     ALPK3 antibodies
     ALPK3 proteins
     Antibodies for ALPK3
     See all of Abcam's Antibodies, Kits and Proteins for ALPK3
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.
     Search LifeMap BioReagents cell lines for ALPK3
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ALPK3
     Browse SwitchGear 3'UTR luciferase reporter plasmids for ALPK3
     SwitchGear Promoter luciferase reporter plasmids for ALPK3
     Search ThermoFisher Antibodies for ALPK3
     Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ALPK3
     inGenious Targeting Laboratory - Custom generated mouse model solutions for ALPK3
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ALPK3
    Customized:
     lentivirus for stable overexpression
     lentivirus expression plasmids for stable overexpression
     adenovirus for overexpression of ALPK3
     LSBio Antibodies in human, mouse, rat for ALPK3
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ALPK3 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4