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ALPK3 Gene

protein-coding   GIFtS: 47
GCID: GC15P085359

Alpha-Kinase 3

  Search for ALPK3
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Alpha-Kinase 31 2     MIDORI2
Muscle Alpha-Kinase1 2     Alpha-Protein Kinase 32
Myocyte Induction Differentiation Originator1 2     EC 2.7.11.-3
Muscle Alpha-Protein Kinase2 3     KIAA13303
MAK2 3     

External Ids:    HGNC: 175741   Entrez Gene: 575382   Ensembl: ENSG000001363837   UniProtKB: Q96L963   

Export aliases for ALPK3 gene to outside databases

Previous GC identifers: GC15P083161 GC15P061446


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ALPK3 Gene:
ALPK3 (alpha-kinase 3) is a protein-coding gene. GO annotations related to this gene include protein serine/threonine kinase activity. An important paralog of this gene is ALPK2.

UniProtKB/Swiss-Prot: ALPK3_HUMAN, Q96L96
Function: Kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical
conformation. Plays a role in cardiomyocyte differentiation (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000015.9  NC_018926.2  NT_010194.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the ALPK3 gene promoter:
         HOXA9B   HOXA9   Sp1   Pax-2   CUTL1   Meis-1b   Evi-1   RORalpha1   Zic3   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidALPK3 promoter sequence
   Search Chromatin IP Primers for ALPK3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ALPK3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q25.2   Ensembl cytogenetic band:  15q25.3   HGNC cytogenetic band: 15q25.2

ALPK3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ALPK3 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15P085359:  view genomic region     (about GC identifiers)

Start:
85,359,911 bp from pter      End:
85,416,713 bp from pter
Size:
56,803 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ALPK3_HUMAN, Q96L96 (See protein sequence)
Recommended Name: Alpha-protein kinase 3  
Size: 1907 amino acids; 201272 Da
Secondary accessions: Q9P2L6

Explore the universe of human proteins at neXtProt for ALPK3: NX_Q96L96

Explore proteomics data for ALPK3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ALPK3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_065829.3  
    ENSEMBL proteins: 
     ENSP00000258888  

    ALPK3 Human Recombinant Protein Products:

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    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for ALPK3 

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    LSBio Antibodies in human, mouse, rat for ALPK3

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    Browse ELISAs at Cloud-Clone Corp.
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    Search eBioscience for ELISAs for ALPK3 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ISET: Immunoglobulin superfamily / I-set domain containing
    IGD: Immunoglobulin superfamily / Immunoglobulin-like domain containing

    IUPHAR Guide to PHARMACOLOGY protein family classification: alpha-kinase 3
    Other alpha kinase family kinases

    Selected InterPro protein domains (see all 6):
     IPR003598 Ig_sub2
     IPR013098 Ig_I-set
     IPR011009 Kinase-like_dom
     IPR013783 Ig-like_fold
     IPR004166 MHCK_EF2_kinase

    Graphical View of Domain Structure for InterPro Entry Q96L96

    ProtoNet protein and cluster: Q96L96

    2 Blocks protein domains:
    IPB003598 Immunoglobulin C-2 type
    IPB013098 Immunoglobulin I-set


    UniProtKB/Swiss-Prot: ALPK3_HUMAN, Q96L96
    Similarity: Belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily
    Similarity: Contains 1 alpha-type protein kinase domain
    Similarity: Contains 2 Ig-like (immunoglobulin-like) domains


    Find genes that share domains with ALPK3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ALPK3_HUMAN, Q96L96
    Function: Kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical
    conformation. Plays a role in cardiomyocyte differentiation (By similarity)

         Enzyme Number (IUBMB): EC 2.7.11.-1

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004674protein serine/threonine kinase activity IEA--
    GO:0005515protein binding ----
    GO:0005524ATP binding IEA--
    GO:0016772transferase activity, transferring phosphorus-containing groups ----
         
    Find genes that share ontologies with ALPK3           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for ALPK3:
     Decreased substrate adherent c 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ALPK3
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ALPK3
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ALPK3

    miRNA
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    miRTarBase miRNAs that target ALPK3:
    hsa-mir-26b-5p (MIRT030251)

    Block miRNA regulation of human, mouse, rat ALPK3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ALPK3 (see all 67):
    hsa-miR-3678-3p hsa-miR-30d hsa-miR-4267 hsa-miR-877* hsa-miR-30a hsa-miR-3622b-3p hsa-miR-4326 hsa-miR-92b
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Predesigned siRNA for gene silencing in human, mouse, rat ALPK3

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    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ALPK3
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ALPK3

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    Browse ESI BIO Cell Lines and PureStem Progenitors for ALPK3 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ALPK3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ALPK3_HUMAN, Q96L96: Nucleus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2
    peroxisome1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ISS--

    Find genes that share ontologies with ALPK3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ALPK3
    Interactions:

        Search GeneGlobe Interaction Network for ALPK3

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for ALPK3 (Q96L963 ENSP000002588884) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006468protein phosphorylation ----
    GO:0007507heart development ISS--

    Find genes that share ontologies with ALPK3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ALPK3



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ALPK3 gene: 
    NM_020778.4  

    Unigene Cluster for ALPK3:

    Alpha-kinase 3
    Hs.459183  [show with all ESTs]
    Unigene Representative Sequence: NM_020778
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000258888(uc002ble.3 uc010upc.2) ENST00000558077
    miRNA
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    Block miRNA regulation of human, mouse, rat ALPK3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ALPK3 (see all 67):
    hsa-miR-3678-3p hsa-miR-30d hsa-miR-4267 hsa-miR-877* hsa-miR-30a hsa-miR-3622b-3p hsa-miR-4326 hsa-miR-92b
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ALPK3 (NM_020778)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ALPK3
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ALPK3
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for ALPK3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ALPK3
      QuantiTect SYBR Green Assays in human, mouse, rat ALPK3
      QuantiFast Probe-based Assays in human, mouse, rat ALPK3

    Additional mRNA sequence: 

    AB037751.1 AK022943.1 AK024829.1 AK026851.1 AK300484.1 AL109725.1 AL109780.1 AL365516.1 
    AL832372.1 AL833276.1 AL833288.1 AY044449.1 BC016870.1 BC040192.1 BC067284.1 

    5 DOTS entries:

    DT.40111744  DT.444015  DT.100748218  DT.95269116  DT.75186144 

    Selected AceView cDNA sequences (see all 91):

    AB037751 CD365087 AK024829 AA629186 F28326 AI468778 BU739292 AL833276 
    BM127139 AA972627 AA969524 AL109725 AL691555 BQ003482 AL832372 BM511791 
    AA969805 CK903393 BF002508 AA878780 AA808727 BX419501 BM127688 AA019539 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ALPK3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGCCAACATT
    ALPK3 Expression
    About this image


    ALPK3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 10) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Heart (Cardiovascular System)    fully expand to see all 2 entries
             Atrioventricular Canal Cells Atrioventricular Canal
             Outflow Tract
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Ovarian Mesenchymal Stroma Cells Ovary Interstitium
             Oviduct
     
     Epithelial Cells
             Mature Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
     
     Bone (Muscoskeletal System)
             Bone Marrow
    ALPK3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ALPK3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.459183
        Custom PCR Arrays for ALPK3
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ALPK3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for ALPK3 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Alpk31 , 5 alpha-kinase 31, 5 79.18(n)1
    74.65(a)1
      7 (45.71 cM)5
    1169041  NM_054085.21  NP_473426.21 
     810576005 
    chicken
    (Gallus gallus)
    Aves ALPK36
    alpha-kinase 3
    39(a)
    1 ↔ 1
    10(390101-419904)
    lizard
    (Anolis carolinensis)
    Reptilia ALPK36
    alpha-kinase 3
    38(a)
    1 ↔ 1
    GL343490.1(126977-167284)
    zebrafish
    (Danio rerio)
    Actinopterygii alpk3a6
    BX001033.26
    Uncharacterized protein
    27(a)
    20(a)
    many → 1
    many → 1
    18(26664154-26697514) ENSDARG00000078989
    7(31446923-31463503) ENSDARG00000090375


    ENSEMBL Gene Tree for ALPK3 (if available)
    TreeFam Gene Tree for ALPK3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ALPK3 gene
    ALPK22  

    Find genes that share paralogs with ALPK3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ALPK3 (see all 1308)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0415264
    A lung large cell carcinoma sample4--see VAR_0415262 Q E mis40--------
    VAR_0415314
    A metastatic melanoma sample4--see VAR_0415312 G E mis40--------
    rs1445592171,2
    C--85357928(+) AGACTC/TTGATG 1 -- us2k10--------
    rs1424726511,2
    C--85357997(+) TTTGG-/CTGT  
            
    CTGTC
    1 -- us2k10--------
    rs1484694901,2
    --85358006(+) CTGTCA/GGGGAA 1 -- us2k10--------
    rs1858542761,2
    --85358055(+) GGTGCA/GAATTT 1 -- us2k10--------
    rs1901805851,2
    --85358435(+) TCCTTA/GTAAAA 1 -- us2k10--------
    rs1831234261,2
    --85358487(+) CTTTGC/GTGCTT 1 -- us2k10--------
    rs1868477151,2
    C--85358528(+) TCCCCC/TGCATC 1 -- us2k10--------
    rs1916814781,2
    --85358547(+) CCTGTC/TCCACC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ALPK3 (85359911 - 85416713 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for ALPK3:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2672879CNV Deletion23128226
    nsv524050CNV Loss19592680
    dgv322n27CNV Gain19166990
    nsv471257CNV Gain18288195
    dgv770e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ALPK3
    DNA2.0 Custom Variant and Variant Library Synthesis for ALPK3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with ALPK3           About GenesLikeMe

    Genetic Association Database (GAD): ALPK3

    Export disorders for ALPK3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ALPK3 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with ALPK3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Alpha-kinases: a new class of protein kinases with a novel catalytic domain. (PubMed id 10021370)1, 2, 3 Ryazanov A.G.... Dorovkov M.V. (Curr. Biol. 1999)
    2. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10718198)1, 2 Nagase T.... Ohara O. (DNA Res. 2000)
    3. Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan. (PubMed id 23648065)1 Low S.K....Nakamura Y. (Cancer Sci. 2013)
    4. Genome-wide association analysis of age-at-onset in Alzheimer's disease. (PubMed id 22005931)1 Kamboh M.I....Lopez O.L. (Mol. Psychiatry 2012)
    5. Patterns of somatic mutation in human cancer genomes. (PubMed id 17344846)2 Greenman C.... Stratton M.R. (Nature 2007)
    6. Analysis of the DNA sequence and duplication history of human chromosome 15. (PubMed id 16572171)2 Zody M.C....Nusbaum C. (Nature 2006)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (Nat. Genet. 2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    9. A novel myocyte-specific gene Midori promotes the differentiation of P19CL6 cells into cardiomyocytes. (PubMed id 11418590)1 Hosoda T....Komuro I. (J. Biol. Chem. 2001)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 57538 HGNC: 17574 AceView: MIDORI Ensembl:ENSG00000136383 euGenes: HUgn57538
    ECgene: ALPK3 H-InvDB: ALPK3

    (According to HUGE)
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    HUGE: KIAA1330

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ALPK3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ALPK3 gene:
    Search GeneIP for patents involving ALPK3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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