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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ALPK1 Gene

protein-coding   GIFtS: 51
GCID: GC04P113218

Alpha-Kinase 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Alpha-Kinase 11 2     KIAA15273 5
LAK2 3 5     8430410J10Rik2
Lymphocyte Alpha-Kinase1 2     Alpha-Protein Kinase 12
Chromosome 4 Kinase2 3     EC 2.7.11.-3
Lymphocyte Alpha-Protein Kinase2 3     

External Ids:    HGNC: 209171   Entrez Gene: 802162   Ensembl: ENSG000000733317   OMIM: 6073475   UniProtKB: Q96QP13   

Export aliases for ALPK1 gene to outside databases

Previous GC identifers: GC04P113657 GC04P113438 GC04P108950


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ALPK1 Gene:
This gene encodes an alpha kinase. Mice which were homozygous for disrupted copies of this gene exhibited
coordination defects (PMID: 21208416). Multiple transcript variants encoding different isoforms have been found
for this gene. (provided by RefSeq, Dec 2011)

GeneCards Summary for ALPK1 Gene: 
ALPK1 (alpha-kinase 1) is a protein-coding gene. Diseases associated with ALPK1 include hepatoblastoma, and alcohol dependence. GO annotations related to this gene include protein serine/threonine kinase activity and ATP binding.

UniProtKB/Swiss-Prot: ALPK1_HUMAN, Q96QP1
Function: Kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical
conformation

Gene Wiki entry for ALPK1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NT_016354.19  NC_018915.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ALPK1 gene promoter:
         AP-2rep   AP-1   HOXA3   FOXO3   Ik-3   FOXO3b   SRY   STAT3   IRF-7A   FOXO3a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): ALPK1 promoter sequence
   Search SABiosciences Chromatin IP Primers for ALPK1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ALPK1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q25   Ensembl cytogenetic band:  4q25   HGNC cytogenetic band: 4q26

ALPK1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ALPK1 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P113218:  view genomic region     (about GC identifiers)

Start:
113,206,665 bp from pter      End:
113,363,776 bp from pter
Size:
157,112 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ALPK1_HUMAN, Q96QP1 (See protein sequence)
Recommended Name: Alpha-protein kinase 1  
Size: 1244 amino acids; 138861 Da
Sequence caution: Sequence=BAC85140.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAC85140.1; Type=Frameshift; Positions=208, 1022; Sequence=BAC85140.1; Type=Miscellaneous discrepancy;
Note=Intron retention; Sequence=BC060780; Type=Frameshift; Positions=1044;
Secondary accessions: B4E3G1 F5H138 Q68CI9 Q6P9F9 Q6ZNK4 Q9P201
Alternative splicing: 2 isoforms:  Q96QP1-1   Q96QP1-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ALPK1: NX_Q96QP1

Explore proteomics data for ALPK1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96QP1

  • ALPK1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ALPK1 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001095876.1  NP_001240813.1  NP_079420.3  

    ENSEMBL proteins: 
     ENSP00000177648   ENSP00000424492   ENSP00000425559   ENSP00000423978   ENSP00000425273  
     ENSP00000398048   ENSP00000426044  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    IUPHAR Guide to PHARMACOLOGY protein family classification: alpha-kinase 1 
    Other alpha kinase family kinases

    2 InterPro protein domains:
     IPR011009 Kinase-like_dom
     IPR004166 MHCK_EF2_kinase

    Graphical View of Domain Structure for InterPro Entry Q96QP1

    ProtoNet protein and cluster: Q96QP1

    UniProtKB/Swiss-Prot: ALPK1_HUMAN, Q96QP1
    Similarity: Belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily
    Similarity: Contains 1 alpha-type protein kinase domain


    ALPK1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ALPK1_HUMAN, Q96QP1
    Function: Kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical
    conformation

         Enzyme Number (IUBMB): EC 2.7.11.-1

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004674protein serine/threonine kinase activity IEA--
    GO:0005524ATP binding IEA--
    GO:0016301kinase activity ----
    GO:0016772transferase activity, transferring phosphorus-containing groups ----
         
    ALPK1 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for ALPK1:
     Decreased viability with RAF26  Increased cell death HMECs cel  Synthetic lethal with paclitax 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ALPK1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ALPK1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ALPK1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ALPK1 

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    3 QIAGEN miScript miRNA Assays for microRNAs that regulate ALPK1:
    hsa-miR-135b hsa-miR-4272 hsa-miR-135a
    SwitchGear 3'UTR luciferase reporter plasmidALPK1 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ALPK1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ALPK1

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for ALPK1 (ENSP000001776484) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYCENSP000003672074STRING: ENSP00000367207
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006468protein phosphorylation ----

    ALPK1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ALPK1

    Search CenterWatch for drugs/clinical trials and news about ALPK1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ALPK1 gene (3 alternative transcripts): 
    NM_001102406.1  NM_001253884.1  NM_025144.3  

    Unigene Cluster for ALPK1:

    Alpha-kinase 1
    Hs.652825  [show with all ESTs]
    Unigene Representative Sequence: AK131090
    18 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000514594 ENST00000505176 ENST00000177648 ENST00000502366 ENST00000509722
    ENST00000505127 ENST00000504488 ENST00000509688(uc003iam.3) ENST00000426472
    ENST00000515330(uc011cfw.1) ENST00000515106 ENST00000504745(uc010imo.3)
    ENST00000505912 ENST00000509209 ENST00000508589 ENST00000512847 ENST00000458497(uc003ian.4 uc003iap.4 uc011cfx.2 uc003iao.4)
    ENST00000504176
    miRNA
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    3 QIAGEN miScript miRNA Assays for microRNAs that regulate ALPK1:
    hsa-miR-135b hsa-miR-4272 hsa-miR-135a
    SwitchGear 3'UTR luciferase reporter plasmidALPK1 3' UTR sequence
    Inhib. RNA
    Products:
         
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ALPK1
    Sirion Biotech Customized lentivirus for stable overexpression of ALPK1 
                         Customized lentivirus expression plasmids for stable overexpression of ALPK1 
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ALPK1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ALPK1

    Additional mRNA sequence: 

    AB040960.1 AB075877.1 AK026323.1 AK026715.1 AK091872.1 AK097246.1 AK131090.1 AK303489.1 
    AK304708.1 AY044164.1 BC028117.1 BC060780.1 BX648798.1 

    14 DOTS entries:

    DT.100711189  DT.308227  DT.100752069  DT.308244  DT.97838581  DT.99938795  DT.75126013  DT.100692258 
    DT.91694344  DT.40115121  DT.91650375  DT.121246011  DT.91792429  DT.97801632 

    24/108 AceView cDNA sequences (see all 108):

    AK097246 AL538538 BE887913 AI660860 AI274270 AL710267 AA307490 BC060780 
    CR590073 AA361352 AA521335 AA443919 AI510764 AI089189 AA235361 AI056941 
    AK091872 AW051462 N59317 CB993532 CB104618 BF439435 AW512699 CA445961 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for ALPK1 (see all 8)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10 ^ 11a · 11b ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18a ·
    SP1:                    -     -     -     -                 -     -           -                                         -                                       
    SP2:                    -     -     -     -                 -     -           -                                         -     -                                 
    SP3:                                                        -     -           -                                                                                 
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 18b
    SP1:      
    SP2:      
    SP3:      
    SP4:      
    SP5:      


    ECgene alternative splicing isoforms for ALPK1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ALPK1 expression in normal human tissues (normalized intensities)      ALPK1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TACCCCTGAA
    ALPK1 Expression
    About this image


    ALPK1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Blood (Hematopoietic System)    fully expand to see all 4 entries
             Double Positive Thymocytes Thymus
             neutrophils   
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Pre-Granulosa Cells Primordial Follicle
     
     Lung (Respiratory System)
             alveolar macrophages   
     
     Thymus (Hematopoietic System)
             Double Positive Thymocytes Thymus

    See ALPK1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ALPK1

    SOURCE GeneReport for Unigene cluster: Hs.652825

    UniProtKB/Swiss-Prot: ALPK1_HUMAN, Q96QP1
    Tissue specificity: Highly expressed in liver

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ALPK1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ALPK1 gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Alpk11 , 5 alpha-kinase 11, 5 77.73(n)1
    72.43(a)1
      3 (56.54 cM)5
    714811  NM_027808.11  NP_082084.11 
     1276703995 
    chicken
    (Gallus gallus)
    Aves ALPK11 alpha-kinase 1 62.16(n)
    55.55(a)
      100858173  XM_003641265.1  XP_003641313.1 
    lizard
    (Anolis carolinensis)
    Reptilia ALPK16
    alpha-kinase 1
    53(a)
    1 ↔ 1
    5(143082607-143154959)
    zebrafish
    (Danio rerio)
    Actinopterygii ALPK16
    alpha-kinase 1
    26(a)
    1 ↔ 1
    7(1073984-1097213)
    worm
    (Caenorhabditis elegans)
    Secernentea efk-16
    Eukaryotic elongation factor 2 kinase
    11(a)
    1 → many
    III(6164919-6168554)


    ENSEMBL Gene Tree for ALPK1 (if available)
    TreeFam Gene Tree for ALPK1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2900 SNPs in ALPK1 are shown (see all 2900)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0415144
    An ovarian mucinous carcinoma sample4--see VAR_0415142 K E mis40--------
    rs1848302771,2
    Cuntested1113352999(+) AGCAGA/C/GGAGAA 6 R G mis10--------
    VAR_0415134
    ----see VAR_0415132 L M mis40--------
    rs793757441,2
    C--113216572(+) TTTCCA/GTAACC 3 -- us2k10--------
    rs1477666321,2
    C--113216602(+) ATCCAC/TAGAAG 3 -- us2k10--------
    rs1410861271,2
    C--113216702(+) AGCCTA/GTAATC 3 -- us2k10--------
    rs1820766261,2
    --113216758(+) AGTTCA/GAGACC 3 -- us2k10--------
    rs1469360791,2
    --113216817(+) AGCTGC/GGCGTG 3 -- us2k10--------
    rs1863285031,2
    --113216863(+) CTGAGA/GCAGGA 3 -- us2k10--------
    rs1915947001,2
    --113216873(+) AGAATC/TGCTTG 3 -- us2k10--------

    HapMap Linkage Disequilibrium report for ALPK1 (113206665 - 113363776 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for ALPK1:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2728152CNV Deletion23290073
    esv2666363CNV Deletion23128226
    esv994179CNV Deletion20482838
    esv2728153CNV Deletion23290073
    esv2152267CNV Deletion18987734
    nsv4470CNV Insertion18451855
    esv26687CNV Loss19812545
    nsv291215CNV Loss16902084

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing ALPK1
    DNA2.0 Custom Variant and Variant Library Synthesis for ALPK1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 607347    OMIM disorders: --

    5 diseases for ALPK1:    About MalaCards
    hepatoblastoma    alcohol dependence    gout    alcoholism
    obesity


    ALPK1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): ALPK1
    Human Genome Epidemiology (HuGE) Navigator: ALPK1 (1 document)

    Export disorders for ALPK1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ALPK1 gene, integrated from 9 sources (see all 20):
    (articles sorted by number of sources associating them with ALPK1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10819331)1, 2, 3 Nagase T.... Ohara O. (2000)
    2. Alpha-kinases: a new class of protein kinases with a novel catalytic domain. (PubMed id 10021370)1, 2, 3 Ryazanov A.G.... Dorovkov M.V. (1999)
    3. A genome-wide association meta-analysis identifies new childhood obesity loci. (PubMed id 22484627)1, 4 Bradfield J.P....Grant S.F. (2012)
    4. Genome-wide association study of epirubicin-induced l eukopenia in Japanese patients. (PubMed id 21799462)1, 4 Srinivasan Y....Zembutsu H. (2011)
    5. A systematic gene-based screen of chr4q22-q32 identif ies association of a novel susceptibility gene, DKK2, with the quantitative tra it of alcohol dependence symptom counts. (PubMed id 20332099)1, 4 Kalsi G....Riley B.P. (2010)
    6. Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas. (PubMed id 15221005)1, 2 Yamada S....Nakagawara A. (2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    9. Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (2002)
    10. Alpha-kinase 1, a new component in apical protein transport. (PubMed id 15883161)1, 9 Heine M....Jacob R. (2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 80216 HGNC: 20917 AceView: LAK Ensembl:ENSG00000073331 euGenes: HUgn80216
    ECgene: ALPK1 H-InvDB: ALPK1

    (According to HUGE)
    About This Section
    HUGE: KIAA1527

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ALPK1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ALPK1 gene:
    Search GeneIP for patents involving ALPK1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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