Aliases for ALPI Gene
External Ids for ALPI Gene
Previous GeneCards Identifiers for ALPI Gene
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The intestinal alkaline phosphatase gene encodes a digestive brush-border enzyme. This enzyme is a component of the gut mucosal defense system and is thought to function in the detoxification of lipopolysaccharide, and in the prevention of bacterial translocation in the gut. [provided by RefSeq, Dec 2014]
GeneCards Summary for ALPI Gene
ALPI (Alkaline Phosphatase, Intestinal) is a Protein Coding gene. Diseases associated with ALPI include Testis Seminoma. Among its related pathways are Thiamine metabolism and Post-translational modification- synthesis of GPI-anchored proteins. GO annotations related to this gene include magnesium ion binding and protease binding. An important paralog of this gene is ALPPL2.