ALOXE3 Gene
protein-coding GIFtS: 56
GCID: GC17M007999
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|
arachidonate lipoxygenase 3
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Aliases for ALOXE3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Arachidonate Lipoxygenase 31 2 | | ARCI32 | | E-LOX1 2 | | Epidermal Lipoxygenase2 | | ELOX31 | | Epidermis-Type Lipoxygenase 32 | | E-LOX-31 | | EC 1.13.11.-3 |
Export aliases for ALOXE3 gene to outside databasesPrevious GC identifers: GC17P008434 GC17M009087 GC17M007941 GC17M008199 GC17M007939 GC17M007894 |
Summaries for ALOXE3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for ALOXE3: This gene is a member of the lipoxygenase family, which are catabolized by arachidonic acid-derived compounds. Theencoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol(8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). Thisepoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha),which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results inichthyosis, implicating the function of this gene in the differentiation of human skin. This gene is part of a clusterof lipoxygenase genes on 17p13.1. Mutations in this gene result in nonbullous congenital ichthyosiform erythroderma(NCIE). Multiple transcript variants encoding different isoforms have been found for this gene.(provided by RefSeq,Sep 2009) UniProtKB/Swiss-Prot: LOXE3_HUMAN, Q9BYJ1Function: Introduces molecular oxygen into polyunsaturated fatty acids. Exact substrate is not known Gene Wiki entry for ALOXE3
|
Genomic Views for ALOXE3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010718.16
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the ALOXE3 gene promoter: Nkx3-1 NF-1/L NF-1 Nkx3-1 v4 Lmo2 Nkx3-1 v1 LCR-F1 HEN1 Nkx3-1 v2 Nkx3-1 v3 Other transcription factors
Search SABiosciences Chromatin IP Primers for ALOXE3
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ALOXE3 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17p13.1 Ensembl cytogenetic band: 17p13.1 HGNC cytogenetic band: 17p13.1ALOXE3 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17M007999: view genomic region
(about GC identifiers)
Start:
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7,999,218 bp from pter |
End:
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8,022,365 bp from pter |
Size:
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23,148 bases |
Orientation:
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minus strand |
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Proteins for ALOXE3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: LOXE3_HUMAN, Q9BYJ1 (See
protein sequence)Recommended Name: Epidermis-type lipoxygenase 3 Size: 711 amino acids; 80543 Da
Cofactor: Binds 1 iron ion per subunit (By similarity)
Secondary accessions: B2R981 B7Z3W0 Q3ZB74 Q9H4F2 Q9HC22Alternative splicing: 2 isoforms: Q9BYJ1-1 Q9BYJ1-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ALOXE3: NX_Q9BYJ1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9BYJ1 ALOXE3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001159432.1 NP_067641.2 ENSEMBL proteins: ENSP00000369494 ENSP00000400581 ENSP00000314879 Human Recombinant Protein Products:
ALOXE3 Antibody Products: Assay Products for ALOXE3: |
Protein
Domains / Families for ALOXE3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ALOXE3 for domains About GeneDecksing
5/7 InterPro domains/families (see all 7):Graphical View of Domain Structure for InterPro Entry Q9BYJ1ProtoNet protein and cluster: Q9BYJ1 3 Blocks protein families: IPB000907 Lipoxygenase IPB001024 Lipoxygenase IPB001885 Mammalian lipoxygenase signature
UniProtKB/Swiss-Prot: LOXE3_HUMAN, Q9BYJ1Similarity: Belongs to the lipoxygenase familySimilarity: Contains 1 lipoxygenase domainSimilarity: Contains 1 PLAT domain |
Function for ALOXE3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: LOXE3_HUMAN, Q9BYJ1Function: Introduces molecular oxygen into polyunsaturated fatty acids. Exact substrate is not knownEnzyme Number (IUBMB): EC 1.13.11.-1
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ALOXE3 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ALOXE3 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): ALOXE3 (NM_021628) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ALOXE3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ALOXE3  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ALOXE3 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005506 | iron ion binding |
IEA | -- | | GO:0016165 | lipoxygenase activity |
IEA | -- |
ALOXE3 for ontologies About GeneDecksing
|
Pathways & Interactions for ALOXE3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Synthesis of Prostaglandins (PG) and Thromboxanes (TX) | |
Pathway sources See GeneCards unified pathways Show all pathways
1 EMD Millipore Pathway for ALOXE3
1 GeneGo (Thomson Reuters) Pathway for ALOXE3
UniProtKB/Swiss-Prot: LOXE3_HUMAN, Q9BYJ1Pathway: Lipid metabolism; leukotriene D4 biosynthesis
ALOXE3 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ALOXE3
STRING Interaction
Network Preview (showing 4 interactants - click image to see more details)
 4 Interacting proteins for ALOXE3 (ENSP000003148794) via UniProtKB, MINT, STRING, and/or I2D About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0019370 | leukotriene biosynthetic process |
IEA | -- |
ALOXE3 for ontologies About GeneDecksing
|
Drugs & Compounds for ALOXE3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
ALOXE3 for compounds About GeneDecksing
Browse Tocris compounds for ALOXE3
1 HMDB Compound for ALOXE3 About this table
| Compound | Synonyms |
CAS
# | PubMed Ids |
|---|
| Iron | Armco iron (see all 19) | 7439-89-6 | -- | 3 Novoseek chemical compound relationships for ALOXE3 gene About this table
Search CenterWatch for drugs/clinical trials and news about ALOXE3 / LOXE3 
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Transcripts for ALOXE3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for ALOXE3 gene (2 alternative transcripts): NM_001165960.1 NM_021628.2 Unigene Cluster for ALOXE3: Arachidonate lipoxygenase 3 Hs.232770 [show with all ESTs]Unigene Representative Sequence: NM_0011659604 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000380149(uc002gka.3 uc010vuo.2) ENST00000448843(uc010cnr.3) ENST00000583808 ENST00000318227(uc010vup.2)
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ALOXE3 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ALOXE3 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): ALOXE3 (NM_021628) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ALOXE3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ALOXE3  |
Additional cDNA sequence: AF182218.1 AJ269499.1 AK292732.1 AK296416.1 AK313677.1 BC101938.1 BC101939.1 BC103508.1 BC104724.1 3 DOTS entries: DT.101977866 DT.86840964 DT.75114519 14 AceView cDNA sequences: BM676593 BM714205 NM_021628 AF182218 AJ269499 AW300461 AW003512 AW613990 AW593980 AK122822 BQ300190 CD693403 BG959287 BQ367813 GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for ALOXE3 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for ALOXE3
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Expression for ALOXE3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ALOXE3 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: TGGTCCCCTT
About this image See ALOXE3 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for ALOXE3
SOURCE GeneReport for Unigene cluster: Hs.232770 UniProtKB/Swiss-Prot: LOXE3_HUMAN, Q9BYJ1Tissue specificity: Predominantly expressed in skin SABiosciences Custom PCR Arrays for ALOXE3
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ALOXE3 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ALOXE3 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ALOXE3 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ALOXE3 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ALOXE3 |
Orthologs for ALOXE3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for ALOXE3 gene from 6/19 species (see all 19) About this table
ENSEMBL Gene Tree for ALOXE3 (if available) TreeFam Gene Tree for ALOXE3 (if available)  |
Paralogs for ALOXE3 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for ALOXE3 gene
- ALOX12B2 ALOX52 ALOX15B2 ALOX122 ALOX152
6 SIMAP similar genes for ALOXE3 using alignment to 2 protein entries: LOXE3_HUMAN (see all proteins):ALOX12B arachidonate 12-lipoxygenase ALOX15B ALOX15 ALOX12 ALOX5
ALOXE3 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for ALOXE3 PGOHUM00000237219
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Genomic Variants for ALOXE3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 17 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for ALOXE3 (7999218 - 8022365 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 2 variations for ALOXE3 1 CNV: 4988 1 Indel: 72788 Human Gene Mutation Database (HGMD): ALOXE3
 | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ALOXE3 |
|
Disorders
/ Diseases for ALOXE3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ALOXE3 for disorders About GeneDecksing
OMIM gene information: 607206 OMIM disorders: 242100 UniProtKB/Swiss-Prot: LOXE3_HUMAN, Q9BYJ1
Defects in ALOXE3 are a cause of non-bullous congenital ichthyosiform erythroderma (NCIE) [MIM:242100]. NCIEis a non-bullous ichthyosis, a skin disorder characterized by abnormal cornification of the epidermis. Most affectedindividuals are born with a tight, shiny, translucent covering called collodion membrane. The collodion membranesubsequently evolves into generalized scaling and intense redness of the skin. Clinical features are milder than inlamellar ichthyoses and demonstrate a greater variability in the intensity of erythema, size and type of scales. Incontrast to lamellar ichthyoses, scales are usually white, fine and powdery, and palms and soles are severelyaffected. Patients suffer from palmoplantar keratoderma, often with painful fissures, digital contractures, and lossof pulp volume 10 diseases for ALOXE3: About MalaCardscongenital ichthyosiform erythroderma ichthyosis autosomal recessive congenital ichthyosis alcoholism anhidrosis epithelial ovarian cancer keratoderma ovarian cancer meningioma leukemia 1 disease from the University of Copenhagen DISEASES database for ALOXE3:Congenital ichthyosiform erythroderma 3 Novoseek disease relationships for ALOXE3 gene About this table
GeneTests: ALOXE3 Autosomal Recessive Congenital Ichthyosis Human Genome Epidemiology (HuGE) Navigator: ALOXE3 (6 documents) Export disorders for ALOXE3 gene to outside databases
|
Publications for ALOXE3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ALOXE3 gene, integrated from 9 sources (see all 33): (articles sorted by number of sources associating them with ALOXE3) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Lipoxygenase-3 (ALOXE3) and 12(R)-lipoxygenase (ALOX12B) are mutated in non-bullous congenital ichthyosiform erythroderma (NCIE) linked to chromosome 17p13.1. (PubMed id 11773004)1, 2, 9 Jobard F.... Fischer J. (2002)
- A gene cluster encoding human epidermis-type lipoxygenases at chromosome 17p13.1: cloning, physical mapping, and expression. (PubMed id 11350124)1, 2, 9 Krieg P.... Fuerstenberger G. (2001)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Human and mouse eLOX3 have distinct substrate specificities: implications for their linkage with lipoxygenases in skin. (PubMed id 17045234)1, 9 Yu Z....Brash A.R. (2006)
- Mutations associated with a congenital form of ichthyosis (NCIE) inactivate the epidermal lipoxygenases 12R-LOX and eLOX3. (PubMed id 15629692)1, 9 Yu Z....Brash A.R. (2005)
- Epidermal lipoxygenase products of the hepoxilin pathway selectively activate the nuclear receptor PPARalpha. (PubMed id 17436029)1, 9 Yu Z....Brash A.R. (2007)
- Genotypic and clinical spectrum of self-improving col lodion ichthyosis: ALOX12B, ALOXE3, and TGM1 mutations in Scandinavian patients . (PubMed id 19890349)1, 9 Vahlquist A....Fischer J. (2010)
- Novel mutations in ALOX12B in patients with autosomal recessive congenital ichthyosis and evidence for genetic heterogeneity on chromosome 17p13. (PubMed id 17139268)1, 9 Lesueur F....Fischer J. (2007)
- Molecular analysis of 250 patients with autosomal recessive congenital ichthyosis: evidence for mutation hotspots in ALOXE3 and allelic heterogeneity in ALOX12B. (PubMed id 19131948)1, 9 Eckl K.M....Hennies H.C. (2009)
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External Searches for ALOXE3 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
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|
Genome Databases showing ALOXE3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ALOXE3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ALOXE3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for ALOXE3 | Pharmacogenomics, SNPs, Pathways | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/ALOXE3 |
|
| | |
About This Section
| Patent Information for ALOXE3 gene: Search GeneIP for patents involving ALOXE3
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for ALOXE3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
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| | | | OriGene Antibodies for ALOXE3 | | OriGene shRNA RFP for ALOXE3 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ALOXE3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ALOXE3 | | OriGene Protein Over-expression Lysate for ALOXE3 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for ALOXE3 | | Browse 3'-UTR reporter clones for miRNA target validation | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ALOXE3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ALOXE3 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for ALOXE3 | | OriGene Custom Protein Services for ALOXE3 | | OriGene Custom Immunoassay Development | | |
| |  |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ALOXE3 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ALOXE3 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ALOXE3 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ALOXE3 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ALOXE3 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ALOXE3 |
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 |  |  |  | |
| | | Search Tocris compounds for ALOXE3 |
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 | | ALOXE3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ALOXE3 |
|  |  |  | | | ThermoFisher Antibodies for ALOXE3 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ALOXE3 |
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