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Aliases for ALOX12P2 Gene

Aliases for ALOX12P2 Gene

  • Arachidonate 12-Lipoxygenase Pseudogene 2 2 3
  • Hair And Skin Epidermal-Type 12-Lipoxygenase-Related Pseudogene 3
  • 12-Lipoxygenase-Related Protein 3
  • ALOX12E 3

External Ids for ALOX12P2 Gene

Summaries for ALOX12P2 Gene

GeneCards Summary for ALOX12P2 Gene

ALOX12P2 (Arachidonate 12-Lipoxygenase Pseudogene 2) is a Pseudogene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ALOX12P2 Gene

Genomics for ALOX12P2 Gene

Genomic Location for ALOX12P2 Gene

Start:
6,853,576 bp from pter
End:
6,954,107 bp from pter
Size:
100,532 bases
Orientation:
Plus strand

Genomic View for ALOX12P2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ALOX12P2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ALOX12P2 Gene

Regulatory Elements for ALOX12P2 Gene

Proteins for ALOX12P2 Gene

Post-translational modifications for ALOX12P2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for ALOX12P2 Gene

Domains for ALOX12P2 Gene

No data available for Gene Families , Protein Domains and UniProtKB/Swiss-Prot for ALOX12P2 Gene

Function for ALOX12P2 Gene

Molecular function for ALOX12P2 Gene

GENATLAS Biochemistry: arachidonate-12-lipoxygenase,epidermal type,expressed pseudogene

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ALOX12P2 Gene

Localization for ALOX12P2 Gene

No data available for Gene Ontology (GO) - Cellular Components for ALOX12P2 Gene

Pathways for ALOX12P2 Gene

SuperPathways for ALOX12P2 Gene

No Data Available

Interacting Proteins for ALOX12P2 Gene

Gene Ontology (GO) - Biological Process for ALOX12P2 Gene

None

No data available for Pathways by source for ALOX12P2 Gene

Transcripts for ALOX12P2 Gene

Unigene Clusters for ALOX12P2 Gene

Arachidonate 12-lipoxygenase pseudogene 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ALOX12P2 Gene

No ASD Table

Relevant External Links for ALOX12P2 Gene

GeneLoc Exon Structure for
ALOX12P2
ECgene alternative splicing isoforms for
ALOX12P2

Expression for ALOX12P2 Gene

mRNA expression in normal human tissues for ALOX12P2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ALOX12P2 Gene

This gene is overexpressed in Pituitary (8.3) and Liver (8.1).

SOURCE GeneReport for Unigene cluster for ALOX12P2 Gene Hs.378695

genes like me logo Genes that share expressions with ALOX12P2: view

Orthologs for ALOX12P2 Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for ALOX12P2 Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia Alox12e 16
Species with no ortholog for ALOX12P2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ALOX12P2 Gene

ENSEMBL:
Gene Tree for ALOX12P2 (if available)
TreeFam:
Gene Tree for ALOX12P2 (if available)

Paralogs for ALOX12P2 Gene

No data available for Paralogs for ALOX12P2 Gene

Variants for ALOX12P2 Gene

Sequence variations from dbSNP and Humsavar for ALOX12P2 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs167476 -- 6,895,612(-) gttga(A/G)aaacc intron-variant
rs167477 -- 6,895,569(-) CTGGA(A/G)ATGGG intron-variant
rs167478 -- 6,895,427(-) TTGAA(A/G)AACAC nc-transcript-variant
rs182577 -- 6,900,071(-) ACTCA(C/G)GGATG nc-transcript-variant
rs186343 -- 6,895,809(-) ctcct(C/T)tcccc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ALOX12P2 Gene

Variant ID Type Subtype PubMed ID
nsv907630 CNV Gain 21882294
esv2422288 CNV Deletion 17116639
nsv521515 CNV Loss 19592680
esv2715590 CNV Deletion 23290073
nsv518777 CNV Gain 19592680
esv21524 CNV Loss 19812545

Relevant External Links for ALOX12P2 Gene

HapMap Linkage Disequilibrium report
ALOX12P2

Disorders for ALOX12P2 Gene

No disorders were found for ALOX12P2 Gene.

No data available for UniProtKB/Swiss-Prot for ALOX12P2 Gene

Publications for ALOX12P2 Gene

  1. Cloning of a human "epidermal-type" 12-lipoxygenase-related gene and chromosomal localization to 17p13. (PMID: 9691181) Sun D. … Funk C.D. (Cytogenet. Cell Genet. 1998) 2 3
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. Genome-wide association study of bipolar disorder accounting for effect of body mass index identifies a new risk allele in TCF7L2. (PMID: 24322204) Winham S.J. … Biernacka J.M. (Mol. Psychiatry 2013) 3
  4. Characterization of human 12-lipoxygenase genes. (PMID: 1570320) Funk C.D. … Samuelsson B. (Proc. Natl. Acad. Sci. U.S.A. 1992) 3

Products for ALOX12P2 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate ALOX12P2
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for ALOX12P2
    • Block miRNA regulation of ALOX12P2 using miScript Target Protectors

    Sources for ALOX12P2 Gene

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