ALOX12B Gene
protein-coding GIFtS: 63
GCID: GC17M007975
|
|
arachidonate 12-lipoxygenase, 12R type
| |
Aliases
for ALOX12B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Arachidonate 12-Lipoxygenase, 12R Type1 2 | | ARCI22 | | 12R-LOX1 2 3 | | Arachidonate 12-Lipoxygenase, 12R-Type2 | | Epidermis-Type Lipoxygenase 122 3 | | EC 1.13.11.-3 | | 12R-Lipoxygenase1 | | EC 1.13.11.338 |
Export aliases for ALOX12B gene to outside databasesPrevious GC identifers: GC17P008465 GC17M008847 GC17M007918 GC17M008176 GC17M007916 GC17M007870 |
Summaries
for ALOX12B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ALOX12B:
This gene encodes an enzyme involved in the converstion of arachidonic acid to 12R-hydroxyeicosatetraenoic acid.Mutations in this gene are associated with nonbullous congenital ichthyosiform erythroderma. (provided by RefSeq, Jul2008)
UniProtKB/Swiss-Prot: LX12B_HUMAN, O75342Function: Converts arachidonic acid to 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE)
Gene Wiki entry for ALOX12B
|
Genomic Views
for ALOX12B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010718.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ALOX12B gene promoter:
E2F-3a E2F-4 E2F-5 p300 E2F-2 HNF-4alpha1 AREB6 E2F-1 E2F
Other transcription factors
Search SABiosciences Chromatin IP Primers for ALOX12B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ALOX12B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17p13.1 Ensembl cytogenetic band: 17p13.1 HGNC cytogenetic band: 17p13.1ALOX12B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17M007975: view genomic region
(about GC identifiers)
Start:
|
7,975,954 bp from pter |
End:
|
7,991,021 bp from pter |
Size:
|
15,068 bases |
Orientation:
|
minus strand |
|
Proteins
for ALOX12B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: LX12B_HUMAN, O75342 (See
protein sequence)Recommended Name: Arachidonate 12-lipoxygenase, 12R-type Size: 701 amino acids; 80356 Da
Cofactor: Binds 1 iron ion per subunit (By similarity)Explore the universe of human proteins at neXtProt for ALOX12B: NX_O75342
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O75342
2 DME Specific Peptides for ALOX12B (O75342)
ALOX12B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001130.1
ENSEMBL proteins: ENSP00000315167 Reactome Protein details: O75342
Human Recombinant Protein Products for ALOX12B:
ALOX12B Antibody Products:
Assay Products for ALOX12B: |
Protein
Domains /
Families
for ALOX12B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ALOX12B for domains About GeneDecksing
5/7 InterPro domains/families (see all 7):Graphical View of Domain Structure for InterPro Entry O75342ProtoNet protein and cluster: O75342 3 Blocks protein families: IPB000907 Lipoxygenase IPB001024 Lipoxygenase IPB001885 Mammalian lipoxygenase signature
UniProtKB/Swiss-Prot: LX12B_HUMAN, O75342Similarity: Belongs to the lipoxygenase familySimilarity: Contains 1 lipoxygenase domainSimilarity: Contains 1 PLAT domain |
Function
for ALOX12B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: LX12B_HUMAN, O75342Function: Converts arachidonic acid to 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE) Enzyme Numbers (IUBMB): EC 1.13.11.332 EC 1.13.11.-1
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
ALOX12B for ontologies About GeneDecksing
Phenotypes:
4 MGI mutant phenotypes (inferred from 4 alleles ) (MGI details for Alox12b):
ALOX12B for phenotypes About GeneDecksing
Animal Models:
Mouse knock-outs for ALOX12B: Alox12btm1Lex Alox12btm1.1Krie
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ALOX12B (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ALOX12B
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ALOX12B (NM_001139) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ALOX12B | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ALOX12B |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ALOX12B |
|
Pathways & Interactions
for ALOX12B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Arachidonic acid metabolism | | | 2 | Metabolism | | | 3 | Synthesis of Prostaglandins (PG) and Thromboxanes (TX) | | | 4 | Synthesis of 15-eicosatetraenoic acid derivatives | | | 5 | Development_PDGF signaling via STATs and NF-kB | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 EMD Millipore Pathways for ALOX12B
2  GeneGo (Thomson Reuters) Pathways for ALOX12B
1  BioSystems Pathway for ALOX12B
4 
Reactome Pathways for ALOX12B
2 
Kegg Pathways (Kegg details for ALOX12B):
UniProtKB/Swiss-Prot: LX12B_HUMAN, O75342Pathway: Lipid metabolism; leukotriene D4 biosynthesis
ALOX12B for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ALOX12B
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/44 Interacting proteins for ALOX12B (O753423 ENSP000003151674) via UniProtKB, MINT, STRING, and/or I2D (see all 44)
About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
ALOX12B for ontologies About GeneDecksing
|
Drugs & Compounds
for ALOX12B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
ALOX12B for compounds About GeneDecksing
 Browse Tocris compounds for ALOX12B
3 HMDB Compounds for ALOX12B About this table
3 Novoseek chemical compound relationships for ALOX12B gene About this table
Search CenterWatch for drugs/clinical trials and news about ALOX12B / LX12B
|
Transcripts
for ALOX12B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ALOX12B gene: NM_001139.2 Unigene Cluster for ALOX12B: Arachidonate 12-lipoxygenase, 12R type Hs.136574 [show with all ESTs]Unigene Representative Sequence: NM_0011394 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000319144(uc002gjy.1) ENST00000577351 ENST00000583276 ENST00000584116
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ALOX12B (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ALOX12B
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ALOX12B (NM_001139) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ALOX12B | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ALOX12B |
Additional cDNA sequence: AF038461.1 AF059250.1 BC041058.1 6 DOTS entries: DT.91785069 DT.97792515 DT.97826992 DT.100695991 DT.102821098 DT.97791482 15 AceView cDNA sequences: BX348205 AF038461 NM_001139 BX095379 BC041058 AF059250 BI667266 BG698713 BG436629 BX331920 BE715737 BM727907 AA649213 BG946103 BM563254
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for ALOX12B About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | - | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ALOX12B
|
Expression
for ALOX12B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ALOX12B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GACACGTTGC
About this image
See ALOX12B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ALOX12B
SOURCE GeneReport for Unigene cluster: Hs.136574
UniProtKB/Swiss-Prot: LX12B_HUMAN, O75342Tissue specificity: Expressed in B-cells, hair follicles, foreskin keratinocytes and adult skin. Also expressed inpsoriatic tissue
SABiosciences Custom PCR Arrays for ALOX12B
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ALOX12B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ALOX12B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ALOX12B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ALOX12B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ALOX12B |
Orthologs
for ALOX12B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for ALOX12B gene from 5/19 species (see all 19) About this table
ENSEMBL Gene Tree for ALOX12B (if available)
TreeFam Gene Tree for ALOX12B (if available) |
Paralogs
for ALOX12B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ALOX12B gene
- ALOX52 ALOX15B2 ALOX122 ALOX152 ALOXE32
5 SIMAP similar genes for ALOX12B using alignment to 1 protein entry: LX12B_HUMAN:ALOXE3 ALOX15B ALOX5 ALOX12 ALOX15
ALOX12B for paralogs About GeneDecksing
|
Genomic Variants
for ALOX12B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ALOX12B (7975954 - 7991021 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for ALOX12B
1 CNV: 4988
Human Gene Mutation Database (HGMD): ALOX12B
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ALOX12B |
|
Disorders
/ Diseases
for ALOX12B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ALOX12B for disorders About GeneDecksing
OMIM gene information: 603741
OMIM disorders: 242100
UniProtKB/Swiss-Prot: LX12B_HUMAN, O75342
Defects in ALOX12B are a cause of non-bullous congenital ichthyosiform erythroderma (NCIE) [MIM:242100]. NCIEis a non-bullous ichthyosis, a skin disorder characterized by abnormal cornification of the epidermis. Most affectedindividuals are born with a tight, shiny, translucent covering called collodion membrane. The collodion membranesubsequently evolves into generalized scaling and intense redness of the skin. Clinical features are milder than inlamellar ichthyoses and demonstrate a greater variability in the intensity of erythema, size and type of scales. Incontrast to lamellar ichthyoses, scales are usually white, fine and powdery, and palms and soles are severelyaffected. Patients suffer from palmoplantar keratoderma, often with painful fissures, digital contractures, and lossof pulp volume
14  diseases for ALOX12B: About MalaCardscongenital ichthyosiform erythroderma autosomal recessive congenital ichthyosis ichthyosis anhidrosis
epithelial ovarian cancer skin disease keratoderma ovarian cancer
tonsillitis dermatitis meningioma breast cancer
leukemia carcinoma
1 disease from the University of Copenhagen DISEASES database for ALOX12B:Congenital ichthyosiform erythroderma 5 Novoseek disease relationships for ALOX12B gene About this table
GeneTests: ALOX12B
Autosomal Recessive Congenital Ichthyosis
Human Genome Epidemiology (HuGE) Navigator: ALOX12B (9 documents)
Export disorders for ALOX12B gene to outside databases
|
Publications
for ALOX12B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ALOX12B gene, integrated from 9 sources (see all 41):
(articles sorted by number of sources associating them with ALOX12B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A 12R-lipoxygenase in human skin: mechanistic evidence, molecular cloning, and expression. (PubMed id 9618483)1, 2, 3, 9 Boeglin W.E.... Brash A.R. (1998)
- A gene cluster encoding human epidermis-type lipoxygenases at chromosome 17p13.1: cloning, physical mapping, and expression. (PubMed id 11350124)1, 2, 9 Krieg P.... Fuerstenberger G. (2001)
- Lipoxygenase-3 (ALOXE3) and 12(R)-lipoxygenase (ALOX12B) are mutated in non-bullous congenital ichthyosiform erythroderma (NCIE) linked to chromosome 17p13.1. (PubMed id 11773004)1, 2, 9 Jobard F.... Fischer J. (2002)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Human 12(R)-lipoxygenase and the mouse ortholog. Molecular cloning, expression, and gene chromosomal assignment. (PubMed id 9837935)1, 2 Sun D.... Funk C.D. (1998)
- Mutations associated with a congenital form of ichthyosis (NCIE) inactivate the epidermal lipoxygenases 12R-LOX and eLOX3. (PubMed id 15629692)1, 9 Yu Z....Brash A.R. (2005)
- Detection and cellular localization of 12R-lipoxygenase in human tonsils. (PubMed id 11368351)1, 9 Schneider C....Brash A.R. (2001)
- Genotypic and clinical spectrum of self-improving col lodion ichthyosis: ALOX12B, ALOXE3, and TGM1 mutations in Scandinavian patients . (PubMed id 19890349)1, 9 Vahlquist A....Fischer J. (2010)
- Self-healing collodion membrane and mild nonbullous congenital ichthyosiform erythroderma due to 2 novel mutations in the ALOX12B gene. (PubMed id 18347291)1, 9 Harting M....Levy M.L. (2008)
- Novel mutations in ALOX12B in patients with autosomal recessive congenital ichthyosis and evidence for genetic heterogeneity on chromosome 17p13. (PubMed id 17139268)1, 9 Lesueur F....Fischer J. (2007)
|
External Searches for ALOX12B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ALOX12B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ALOX12B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ALOX12B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ALOX12B | Pharmacogenomics, SNPs, Pathways | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/ALOX12B |
|
| | |
About This Section
| Patent Information for ALOX12B gene:
Search GeneIP for patents involving ALOX12B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ALOX12B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ALOX12B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ALOX12B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ALOX12B | | | OriGene Protein Over-expression Lysate for ALOX12B | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ALOX12B | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ALOX12B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ALOX12B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ALOX12B | | OriGene Custom Protein Services for ALOX12B | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ALOX12B | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ALOX12B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ALOX12B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ALOX12B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ALOX12B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ALOX12B |
| |
 |  |  |  | |
| | | | Search Tocris compounds for ALOX12B |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | ALOX12B Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ALOX12B |
|  |  |  |  | | | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ALOX12B |
| |  | |
|
|
|
