ALMS1P Gene
pseudogene GIFtS: 31
GCID: GC02P073872
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Alstrom syndrome 1 pseudogene(Previous name: Alstrom syndrome 1-like )
(Previous symbol: ALMS1L)
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Aliases
for ALMS1P gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
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| Alstrom Syndrome 1 Pseudogene1 2 | | ALMS1L1 2 3 | | Alstrom Syndrome 1-Like1 |
| External Ids: | HGNC: 295861 | Entrez Gene: 2004202 | Ensembl: ENSG000001630167 | UniProtKB: Q96L163 | | ORGUL members: | |
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| NONCODE:n406230 | |
Export aliases for ALMS1P gene to outside databasesPrevious GC identifers: GC02P073721 GC02P073868 GC02P073607
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Summaries
for ALMS1P gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
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-- |
Genomic Views
for ALMS1P gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_022184.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ALMS1P gene promoter:
p53 NRSF form 1 Cart-1 Nkx2-5 NRSF form 2
Other transcription factors
Search SABiosciences Chromatin IP Primers for ALMS1P
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ALMS1P |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2p13.1 Ensembl cytogenetic band: 2p13.1 HGNC cytogenetic band: 2p13.2ALMS1P Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02P073872: view genomic region
(about GC identifiers)
Start:
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73,872,046 bp from pter |
End:
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73,912,703 bp from pter |
Size:
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40,658 bases |
Orientation:
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plus strand |
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Proteins
for ALMS1P gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ALM1L_HUMAN, Q96L16 (See
protein sequence)Recommended Name: Putative ALMS1-like protein Size: 210 amino acids; 24624 Da
Miscellaneous: The protein is highly similar to the C-terminus of ALMS1
Caution: Could be the product of a pseudogeneExplore the universe of human proteins at neXtProt for ALMS1P: NX_Q96L16
ALMS1P Protein expression data from MOPED and PaxDb: --
Human Recombinant Protein Products for ALMS1P:
ALMS1P Antibody Products:
Assay Products for ALMS1P: |
Protein
Domains /
Families
for ALMS1P gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q96L16 |
Function
for ALMS1P gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
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Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ALMS1P
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ALMS1P
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for ALMS1P | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ALMS1P | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ALMS1P |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ALMS1P |
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Pathways & Interactions
for ALMS1P gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ALMS1P
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Drugs & Compounds
for ALMS1P gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ALMS1P
Search CenterWatch for drugs/clinical trials and news about ALMS1P
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Transcripts
for ALMS1P gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
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REFSEQ mRNAs for ALMS1P gene: NM_145300.1 Unigene Cluster for ALMS1P: Alstrom syndrome 1 pseudogene Hs.278983 [show with all ESTs]Unigene Representative Sequence: BC0144922 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000450720(uc010yrl.2) ENST00000428767
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ALMS1P
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ALMS1P
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for ALMS1P | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ALMS1P | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ALMS1P |
Additional cDNA sequence: AK307160.1 BC014492.1 NR_003683.2 3 DOTS entries: DT.313705 DT.95132786 DT.408958 16 AceView cDNA sequences: AA862557 BF435095 AA577579 BG334072 AW083995 BC014492 NM_145300 BG745759 BX108483 BV197163 BG746272 BG474872 BG475683 AA972002 BG475985 BG475634
GeneLoc Exon Structure
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Expression
for ALMS1P gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ALMS1P expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TAAAACAAAA
About this image
Genevestigator expression for ALMS1P
SOURCE GeneReport for Unigene cluster: Hs.278983
SABiosciences Custom PCR Arrays for ALMS1P
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ALMS1P
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ALMS1P | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ALMS1P | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ALMS1P | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ALMS1P |
Orthologs
for ALMS1P gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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ENSEMBL Gene Tree for ALMS1P (if available)
TreeFam Gene Tree for ALMS1P (if available) |
Paralogs
for ALMS1P gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
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Genomic Variants
for ALMS1P gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
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| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for ALMS1P (73872046 - 73912703 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 10 variations for ALMS1P
10 CNVs: 50554 9415 37799 50555 97885 47854 3365 9944 50553 9416 | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for ALMS1P gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
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ALMS1P for disorders About GeneDecksing
2  diseases for ALMS1P: About MalaCardsalstrom syndrome kidney disease
Export disorders for ALMS1P gene to outside databases
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Publications
for ALMS1P gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
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PubMed articles for ALMS1P gene integrated from 9 sources:
(articles sorted by number of sources associating them with ALMS1P) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Genetic loci influencing kidney function and chronic kidney disease. (PubMed id 20383145)1 Chambers J.C....Kooner J.S. (2010)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
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External Searches for ALMS1P gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing ALMS1P gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing ALMS1P gene
(According to HUGE)
About This Section
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Specialized Databases showing ALMS1P gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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About This Section
| Patent Information for ALMS1P gene:
Search GeneIP for patents involving ALMS1P
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ALMS1P gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ALMS1P | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ALMS1P | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ALMS1P | | | OriGene Protein Over-expression Lysate for ALMS1P | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ALMS1P | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ALMS1P | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ALMS1P | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ALMS1P | | OriGene Custom Protein Services for ALMS1P | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ALMS1P | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ALMS1P | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ALMS1P | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ALMS1P | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ALMS1P | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ALMS1P |
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| | | | Search Tocris compounds for ALMS1P |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ALMS1P |
|  |  |  |  | | | | Search ThermoFisher Antibodies for ALMS1P |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ALMS1P |
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Last full update: 18 Mar 2013 -
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