ALMS1 Gene
protein-coding GIFtS: 57
GCID: GC02P073612
|
|
Alstrom syndrome 1
| |
Aliases
for ALMS1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Alstrom Syndrome 11 2 | | KIAA03281 3 5 | | ALSS2 5 | | Alstrom Syndrome Protein 12 |
Export aliases for ALMS1 gene to outside databasesPrevious GC identifers: GC02P073622 GC02P073823 GC02P073587 GC02P073524 GC02P073466 GC02P073348 |
Summaries
for ALMS1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ALMS1:
This gene encodes a protein containing a large tandem-repeat domain. The mouse ortholog of this gene has been shown tofunction in ciliogenesis in inner medullary collecting duct cells. Mutations in this gene have been associated withAlstrom syndrome. Alternative splice variants have been described but their full length sequences have not beendetermined.(provided by RefSeq, Mar 2009)
UniProtKB/Swiss-Prot: ALMS1_HUMAN, Q8TCU4Function: Involved in PCM1-dependent intracellular transport. Required, directly or indirectly, for the localization ofNCAPD2 to the proximal ends of centrioles. Required for proper formation and/or maintenance of primary cilia (PC),microtubule-based structures that protrude from the surface of epithelial cells
|
Genomic Views
for ALMS1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_022184.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ALMS1 gene promoter:
TBP Pax-5 AML1a Egr-1 FOXD1 STAT5A TFIID Sox9 ZID Zic3
Other transcription factors
Search SABiosciences Chromatin IP Primers for ALMS1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ALMS1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2p13 Ensembl cytogenetic band: 2p13.1 HGNC cytogenetic band: 2p13.1ALMS1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02P073612: view genomic region
(about GC identifiers)
Start:
|
73,612,886 bp from pter |
End:
|
73,837,920 bp from pter |
Size:
|
225,035 bases |
Orientation:
|
plus strand |
|
Proteins
for ALMS1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ALMS1_HUMAN, Q8TCU4 (See
protein sequence)Recommended Name: Alstrom syndrome protein 1 Size: 4167 amino acids; 460965 Da
Subcellular location: Cytoplasm. Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytoskeleton, cilium basal body.Cytoplasm, cytoskeleton, spindle pole. Note=Associated with centrosomes and basal bodies at the base of primary cilia.Specifically locates to the proximal ends of centrioles and basal bodies. Colocalizes partially with NCAPD2 at thesesites. During mitosis localizes to both spindle poles
Developmental stage: Widely expressed in fetal tissues. Detected in fetal pancreas, skeletal muscle, liver, kidney andbrain (at protein level). Expressed in fetal aorta and brain
Secondary accessions: Q53S05 Q580Q8 Q86VP9 Q9Y4G4Alternative splicing: 3 isoforms: Q8TCU4-1 Q8TCU4-2 Q8TCU4-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ALMS1: NX_Q8TCU4
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8TCU4
ALMS1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_055935.4
ENSEMBL proteins: ENSP00000386627 ENSP00000264448 ENSP00000399833 ENSP00000366944 Reactome Protein details: Q8TCU4
Human Recombinant Protein Products:
Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7): About this table
ALMS1 for ontologies About GeneDecksing
ALMS1 Antibody Products:
Assay Products for ALMS1: |
Protein
Domains /
Families
for ALMS1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q8TCU4 |
Function
for ALMS1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ALMS1_HUMAN, Q8TCU4Function: Involved in PCM1-dependent intracellular transport. Required, directly or indirectly, for the localization ofNCAPD2 to the proximal ends of centrioles. Required for proper formation and/or maintenance of primary cilia (PC),microtubule-based structures that protrude from the surface of epithelial cells
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ALMS1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ALMS1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ALMS1 (NM_015120) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ALMS1 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ALMS1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ALMS1 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003674 | molecular_function |
ND | -- |
ALMS1 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for ALMS1:
Animal Models:
12 MGI mutant phenotypes (inferred from 4 alleles ) (MGI details for Alms1):
ALMS1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for ALMS1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Recruitment of mitotic centrosome proteins and complexes | | | 2 | Cell Cycle | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/8 
Reactome Pathways for ALMS1 (see all 8)
ALMS1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ALMS1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/57 Interacting proteins for ALMS1 (Q8TCU41, 3 ENSP000002644484) via UniProtKB, MINT, STRING, and/or I2D (see all 57)About this table
Gene Ontology (GO): 5/23 biological process terms (GO ID links to tree view) (see all 23): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000086 | G2/M transition of mitotic cell cycle |
TAS | -- | | GO:0000278 | mitotic cell cycle |
TAS | -- | | GO:0001736 | establishment of planar polarity |
IEA | -- | | GO:0006629 | lipid metabolic process |
-- | -- | | GO:0006641 | triglyceride metabolic process |
IEA | -- |
ALMS1 for ontologies About GeneDecksing
|
Drugs & Compounds
for ALMS1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ALMS1
Search CenterWatch for drugs/clinical trials and news about ALMS1
|
Transcripts
for ALMS1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ALMS1 gene: NM_015120.4 Unigene Cluster for ALMS1: Alstrom syndrome 1 Hs.184720 [show with all ESTs]Unigene Representative Sequence: AJ4175938 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000409009(uc002sjg.3 uc002sjh.1) ENST00000264448(uc002sje.1 uc002sjf.1)
ENST00000423048(uc010fev.1) ENST00000484298 ENST00000476650 ENST00000464408
ENST00000490821 ENST00000377715
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ALMS1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ALMS1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ALMS1 (NM_015120) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ALMS1 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ALMS1 |
Additional cDNA sequence: AB002326.3 AJ417593.2 AL833495.1 BC035025.2 BC050330.1 BX647706.1 BX648632.1 EF151141.1 13 DOTS entries: DT.314966 DT.75155839 DT.100816254 DT.92422157 DT.100036543 DT.100671819 DT.99997664 DT.100036545 DT.101963353 DT.121008213 DT.121008226 DT.92422155 DT.95299663 24/146 AceView cDNA sequences (see all 146): BX088771 NM_015120 AI741793 F10219 AB002326 AA913775 F12602 BU617556 BP369149 BX951838 AJ417593 AX751581 BM452035 AW386108 BU727724 BQ017018 AW473187 BM723326 BC035025 BU154288 BC050330 AL045603 AL833495 AL704019
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for ALMS1 (see all 8) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | · | 8c | · | 8d | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | · | 12c | ^ | 13a | · | 13b | · | 13c | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19a | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | | | | | - | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 19b | · | 19c | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23 | ^ | 24 | ^ | 25 | ^ | 26a | · | 26b | ^ | 27 | ^ | 28 |
|---|
|
| SP1: | | | - | | - | | - | | | | | | | | | | | | - | | | | | | |
| SP2: | | | - | | - | | - | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | - | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ALMS1
|
Expression
for ALMS1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ALMS1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGTATTTTAG
About this image
See ALMS1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ALMS1
SOURCE GeneReport for Unigene cluster: Hs.184720
UniProtKB/Swiss-Prot: ALMS1_HUMAN, Q8TCU4Tissue specificity: Expressed in all tissues tested including adipose and pancreas. Expressed by beta-cells of theislets in the pancreas (at protein level)
SABiosciences Expression via Pathway-Focused PCR Array including ALMS1:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ALMS1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ALMS1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ALMS1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ALMS1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ALMS1 |
Orthologs
for ALMS1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ALMS1 gene from 4/14 species (see all 14) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
ALMS16 |
Uncharacterized protein |
40(a) |
1 ↔ 1 |
4(93152910-93163012) |
lizard
(Anolis carolinensis) |
Reptilia |
ALMS16 |
-- |
23(a) |
1 ↔ 1 |
GL343639.1(92685-137651) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.37782 |
Xenopus laevis transcribed sequences |
75.56(n) |
|
48031315 |
zebrafish
(Danio rerio) |
Actinopterygii |
si:dkey-265c15.26 |
si:dkey-265c15.2 |
19(a) |
1 ↔ 1 |
13(8733976-8771516) |
ENSEMBL Gene Tree for ALMS1 (if available)
TreeFam Gene Tree for ALMS1 (if available) |
Paralogs
for ALMS1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ALMS1 gene
- C10orf902
1 SIMAP similar gene for ALMS1 using alignment to 6 protein entries: ALMS1_HUMAN (see all proteins):ALMS1P
ALMS1 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for ALMS1
PGOHUM00000240684 PGOHUM00000240685
|
Genomic Variants
for ALMS1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ALMS1 (73612886 - 73837920 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for ALMS1
2 CNVs: 3365 97884
Human Gene Mutation Database (HGMD): ALMS1
Locus Specific Mutation Databases (LSDB): ALMS1
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ALMS1 |
|
Disorders
/ Diseases
for ALMS1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ALMS1 for disorders About GeneDecksing
OMIM gene information: 606844
OMIM disorders: 203800
UniProtKB/Swiss-Prot: ALMS1_HUMAN, Q8TCU4
Defects in ALMS1 are the cause of Alstrom syndrome (ALMS) [MIM:203800]. Alstrom syndrome is a rare autosomalrecessive disorder characterized by progressive cone-rod retinal dystrophy, neurosensory hearing loss, early childhoodobesity and type 2 diabetes mellitus. Dilated cardiomyopathy, acanthosis nigricans, male hypogonadism, hypothyroidism,developmental delay and hepatic dysfunction can also be associated with the syndrome
17  diseases for ALMS1: About MalaCardsalstrom syndrome cone-rod dystrophy bardet-biedl syndrome acanthosis nigricans
type 2 diabetes mellitus diabetes mellitus cellulitis insulin resistance
hypogonadism kidney disease retinal disease retinitis
blindness obesity cholesterol hepatitis
leber congenital amaurosis
4 diseases from the University of Copenhagen DISEASES database for ALMS1:cone-rod dystrophy Sensorineural hearing loss Dilated cardiomyopathy Blindness GeneTests: ALMS1
Alstrom Syndrome
Human Genome Epidemiology (HuGE) Navigator: ALMS1 (9 documents)
Export disorders for ALMS1 gene to outside databases
|
Publications
for ALMS1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ALMS1 gene, integrated from 9 sources (see all 51):
(articles sorted by number of sources associating them with ALMS1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Mutation of ALMS1, a large gene with a tandem repeat encoding 47 amino acids, causes Alstrom syndrome. (PubMed id 11941370)1, 2, 9 Hearn T.... Wilson D.I. (2002)
- Mutations in ALMS1 cause obesity, type 2 diabetes and neurosensory degeneration in Alstrom syndrome. (PubMed id 11941369)1, 2, 9 Collin G.B....Naggert J.K. (2002)
- Centriolar association of ALMS1 and likely centrosoma l functions of the ALMS motif-containing proteins C10orf90 and KIAA1731. (PubMed id 20844083)1, 2 Knorz V.J....Hearn T. (2010)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
- Subcellular localization of ALMS1 supports involvement of centrosome and basal body dysfunction in the pathogenesis of obesity, insulin resistance, and type 2 diabetes. (PubMed id 15855349)1, 2 Hearn T.... Wilson D.I. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Proteomic characterization of the human centrosome by protein correlation profiling. (PubMed id 14654843)1, 2 Andersen J.S....Mann M. (2003)
- Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (2002)
- Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9205841)1, 2 Nagase T.... Ohara O. (1997)
- Homozygosity mapping at Alstrom syndrome to chromosome 2p. (PubMed id 9063741)1, 3 Collin G.B....Nishina P.M. (1997)
|
External Searches for ALMS1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ALMS1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ALMS1 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing ALMS1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ALMS1 | Pharmacogenomics, SNPs, Pathways | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/ALMS1 |
|
| | |
About This Section
| Patent Information for ALMS1 gene:
Search GeneIP for patents involving ALMS1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ALMS1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for ALMS1 | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ALMS1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ALMS1 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ALMS1 | | OriGene 3'-UTR Clone for ALMS1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ALMS1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ALMS1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ALMS1 | | OriGene Custom Protein Services for ALMS1 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ALMS1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ALMS1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ALMS1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ALMS1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ALMS1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ALMS1 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for ALMS1 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | ALMS1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ALMS1 |
|  |  |  | | | | ThermoFisher Antibodies for ALMS1 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ALMS1 |
|
|
|
|
