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ALLC Gene

protein-coding   GIFtS: 52
GCID: GC02P003705

Allantoicase

  See ALLC-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
allantoicase1 2
Allantoate Amidinohydrolase2 3
EC 3.5.3.43 8
ALC2
Probable Allantoicase2

External Ids:    HGNC: 173771   Entrez Gene: 558212   Ensembl: ENSG000001513607   OMIM: 6123965   UniProtKB: Q8N6M53   

Export aliases for ALLC gene to outside databases

Previous GC identifers: GC02P003183 GC02P003348 GC02P003270 GC02P003199 GC02P003683


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ALLC Gene:
Allantoicase (EC 3.5.3.4) participates in the uric acid degradation pathway. Its enzymatic activity, like that of
urate oxidase (MIM 191540), was lost during vertebrate evolution.(supplied by OMIM, Nov 2008)

GeneCards Summary for ALLC Gene:
ALLC (allantoicase) is a protein-coding gene. Diseases associated with ALLC include denture stomatitis, and lymphogranuloma venereum. GO annotations related to this gene include allantoicase activity.

UniProtKB/Swiss-Prot: ALLC_HUMAN, Q8N6M5
Function: The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NT_005334.17  NC_018913.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ALLC gene promoter:
         PPAR-gamma1   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidALLC promoter sequence
   Search Chromatin IP Primers for ALLC

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ALLC


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q35   Ensembl cytogenetic band:  2p25.3   HGNC cytogenetic band: 2p25.3

ALLC Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ALLC gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P003705:  view genomic region     (about GC identifiers)

Start:
3,705,785 bp from pter      End:
3,750,261 bp from pter
Size:
44,477 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: ALLC_HUMAN, Q8N6M5 (See protein sequence)
Recommended Name: Probable allantoicase  
Size: 410 amino acids; 45750 Da
Sequence caution: Sequence=AAY24236.1; Type=Erroneous gene model prediction;
Secondary accessions: Q53T95 Q5RL81 Q96RE6 Q9NZA7
Alternative splicing: 2 isoforms:  Q8N6M5-1   Q8N6M5-2   

Explore the universe of human proteins at neXtProt for ALLC: NX_Q8N6M5

Explore proteomics data for ALLC at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for ALLC (Q8N6M5) (see all 10)
     PDGGVSR  GKWMDGW  LLPVTKL  DGWETRR 


    See ALLC Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060906.3  
    ENSEMBL proteins: 
     ENSP00000252505  

    ALLC Human Recombinant Protein Products:

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    Novus Biologicals ALLC Proteins
    Novus Biologicals ALLC Lysates
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    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ALLC

     
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    antibodies-online proteins for ALLC (16 products) 

     
    antibodies-online peptides for ALLC

    ALLC Antibody Products:

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    antibodies-online antibodies for ALLC (12 products) 

    ALLC Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for ALLC
    Cloud-Clone Corp. CLIAs for ALLC
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    antibodies-online kits for ALLC (7 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR005164 Allantoicase
     IPR008979 Galactose-bd-like
     IPR015908 Allantoicase_dom

    Graphical View of Domain Structure for InterPro Entry Q8N6M5

    ProtoNet protein and cluster: Q8N6M5

    1 Blocks protein domain: IPB005164 Allantoicase repeat

    UniProtKB/Swiss-Prot: ALLC_HUMAN, Q8N6M5
    Similarity: Belongs to the allantoicase family


    Find genes that share domains with ALLC           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ALLC_HUMAN, Q8N6M5
    Function: The function of this enzyme is unclear as allantoicase activity is not known to exist in mammals
    Catalytic activity: Allantoate + H(2)O = (S)-ureidoglycolate + urea

         Enzyme Number (IUBMB): EC 3.5.3.41 2

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004037allantoicase activity IEA--
         
    Find genes that share ontologies with ALLC           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for ALLC:
     Synthetic lethal with Ras 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for ALLC

    miRNA
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    2 qRT-PCR Assays for microRNAs that regulate ALLC:
    hsa-miR-124* hsa-miR-3934
    SwitchGear 3'UTR luciferase reporter plasmidALLC 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for ALLC
    Predesigned siRNA for gene silencing in human, mouse, rat ALLC

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ALLC

    Clone
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    OriGene clones in human, mouse for ALLC (see all 5)
    OriGene ORF clones in mouse, rat for ALLC
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    GenScript: all cDNA clones in your preferred vector: ALLC (NM_018436)
    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ALLC

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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ALLC


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton3
    extracellular2
    nucleus2
    peroxisome2
    chloroplast1
    cytosol1
    mitochondrion1
    plasma membrane1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ALLC About    
    See pathways by source

    SuperPathContained pathways About
    1Purine metabolism (KEGG)
    Purine metabolism0.38
    2Metabolism
    Metabolic pathways0.38


    Find genes that share SuperPaths with ALLC           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    2 Kegg Pathways  (Kegg details for ALLC):
        Purine metabolism
    Metabolic pathways

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ALLC
    Interactions:

        GeneGlobe Interaction Network for ALLC

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    Selected Interacting proteins for ALLC (Q8N6M53 ENSP000002525054) via UniProtKB, MINT, STRING, and/or I2D (see all 12)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ACSL4O604883I2D: score=1 
    ADCK3Q8NI603I2D: score=1 
    CBSP355203I2D: score=1 
    HSP90AA1P079003I2D: score=1 
    NAP1L4Q997333I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000256allantoin catabolic process IEA--

    Find genes that share ontologies with ALLC           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ALLC

    4 HMDB Compounds for ALLC    About this table
    CompoundSynonyms CAS #PubMed Ids
    (S)-Ureidoglycolic acid(-)-Ureidoglycolate (see all 7)7424-03-5--
    Allantoic acidAllantoate (see all 4)99-16-1--
    UreaCarbonyl diamine (see all 90)57-13-6--
    WaterDihydrogen oxide (see all 2)7732-18-5--

    1 Novoseek inferred chemical compound relationship for ALLC gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    uric acid 58.4 2 11330038 (1)



    Find genes that share compounds with ALLC           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ALLC gene (2 alternative transcripts): 
    NM_199232.1  NM_018436.3  

    Unigene Cluster for ALLC:

    Allantoicase
    Hs.97899  [show with all ESTs]
    Unigene Representative Sequence: BC035356
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000252505(uc010ewt.3) ENST00000476389(uc002qyf.3) ENST00000471711

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ALLC using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate ALLC:
    hsa-miR-124* hsa-miR-3934
    SwitchGear 3'UTR luciferase reporter plasmidALLC 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ALLC
    Predesigned siRNA for gene silencing in human, mouse, rat ALLC
    Clone
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    OriGene ORF clones in mouse, rat for ALLC
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ALLC (NM_018436)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ALLC
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ALLC
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for ALLC
    OriGene qSTAR qPCR primer pairs in human, mouse for ALLC
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ALLC
      QuantiTect SYBR Green Assays in human, mouse, rat ALLC
      QuantiFast Probe-based Assays in human, mouse, rat ALLC

    Additional mRNA sequence: 

    AF215924.1 AF395820.1 AK302299.1 BC029652.1 BC035356.1 

    2 DOTS entries:

    DT.101976687  DT.100017183 

    24 AceView cDNA sequences:

    NM_199232 AA402997 BC035356 BI825480 BQ189212 AI910694 AF215924 AF395820 
    BP371512 BC029652 BX096226 NM_018436 AA469952 BX280147 AI948860 AA421584 
    BE465476 AA412027 AA708163 CK299381 BQ000277 AW886703 BI832436 AI627963 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ALLC expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTGAAGTTCT
    ALLC Expression
    About this image


    ALLC expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 8) fully expand
     
     Brain (Nervous System)    fully expand to see all 5 entries
             Mature Endothelial Cells Blood Brain Barrier
             Cerebral Cortex
     
     Testis (Reproductive System)    fully expand to see all 2 entries
             Mature Sertoli Cells Seminiferous Tubules
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Ovarian Mesenchymal Stroma Cells Ovary Interstitium
             Oviduct
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
    ALLC Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ALLC Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.97899
        Custom PCR Arrays for ALLC
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ALLC

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for ALLC gene from Selected species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Allc1 , 5 allantoicase1, 5 80.17(n)1
    80.51(a)1
      12 (10.97 cM)5
    940411  NM_053156.21  NP_444386.21 
     285537555 
    lizard
    (Anolis carolinensis)
    Reptilia ALLC6
    allantoicase
    53(a)
    1 ↔ 1
    GL343342.1(1177733-1192657)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC685812 hypothetical protein MGC68581 73.88(n)    AF153230.1 
    zebrafish
    (Danio rerio)
    Actinopterygii allc1 allantoicase 60.93(n)
    56.28(a)
      436989  NM_001002716.2  NP_001002716.1 
    mosquito
    (Anopheles gambiae)
    Insecta AgaP_AGAP0045011 AgaP_AGAP004501 49.81(n)
    48.86(a)
      1274647  XM_313798.5  XP_313798.5 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes DAL2(YIR029W)4
    DAL21
    Allantoicase, converts allantoate to urea and ureidoglycolate more4
    DAL21
    46.16(n)1
    35.02(a)1
      9(410807-411838)4
    8548471, 4  NP_012295.11, 4 


    ENSEMBL Gene Tree for ALLC (if available)
    TreeFam Gene Tree for ALLC (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ALLC (see all 1055)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs778090161,2
    C,F--3703898(+) CGAGAG/ACAGCC 1 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs170178441,2
    C,F,H--3703907(+) CCTCAC/TGTCTG 1 -- us2k119Minor allele frequency- T:0.06NA NS EA CSA WA 2357
    rs802123231,2
    C,F--3703959(+) GTTCTC/TCTCCC 1 -- us2k13Minor allele frequency- T:0.09NA EA 242
    rs731388851,2
    C,F--3703964(+) CCTCCC/TGCCCC 1 -- us2k13Minor allele frequency- T:0.26WA 122
    rs1496871351,2
    --3703988(+) CAGGAC/TGTCTG 1 -- us2k10--------
    rs1164361661,2
    F--3704039(+) CTGTCG/ACCTCT 1 -- us2k11Minor allele frequency- A:0.02WA 118
    rs739103211,2
    C,F--3704078(+) CTTACC/TTCATA 1 -- us2k11Minor allele frequency- T:0.50WA 2
    rs1509491841,2
    C--3704177(+) ACGTC-/GGATGG 1 -- us2k10--------
    rs353985361,2
    C,F--3704240(+) CCCAGC/TATCGC 1 -- us2k16Minor allele frequency- T:0.23NA WA 246
    rs1853593301,2
    --3704399(+) GGCAGA/GGGTCA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ALLC (3705785 - 3750261 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for ALLC (see all 23):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2719526CNV Deletion23290073
    esv2719525CNV Deletion23290073
    esv2656614CNV Deletion23128226
    esv2660703CNV Deletion23128226
    esv2719527CNV Deletion23290073
    esv2428176CNV Deletion19546169
    esv271682CNV Insertion20981092
    nsv2574CNV Insertion18451855
    esv273654CNV Insertion20981092
    nsv2575CNV Loss18451855

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ALLC
    DNA2.0 Custom Variant and Variant Library Synthesis for ALLC

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 612396    OMIM disorders: --

    2 diseases for ALLC:    
    About MalaCards
    denture stomatitis    lymphogranuloma venereum

    5 diseases from the University of Copenhagen DISEASES database for ALLC:
    Diabetes mellitus     Candidiasis     Diarrhea     Lymphogranuloma venereum
    Denture stomatitis

    Find genes that share disorders with ALLC           About GenesLikeMe


    Export disorders for ALLC gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ALLC gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with ALLC)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human allantoicase gene: cDNA cloning, genomic organization and chromosome localization. (PubMed id 11054555)1, 2, 3, 9 Vigetti D.... Bernardini G. (Gene 2000)
    2. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W.... Wilson R.K. (Nature 2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Genomic organization and chromosome localization of the murine and human allantoicase gene. (PubMed id 12036579)1, 2 Vigetti D.... Bernardini G. (Gene 2002)
    5. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (PLoS ONE 2012)
    6. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    8. Evolution of urate-degrading enzymes in animal peroxisomes. (PubMed id 11330038)9 Hayashi S....Noguchi T. (Cell Biochem. Biophys. 2000)
    9. Selective pressure on the allantoicase gene during vertebrate evolution. (PubMed id 14745534)9 Vigetti D....Gornati R. (J. Mol. Evol. 2003)
    10. A new type of allantoinase in amphibian liver. (PubMed id 11791734)9 Masuda W....Noguchi T. (Biosci. Biotechnol. Biochem. 2001)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Aliases
    Free Text  

      Query String
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    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55821 HGNC: 17377 AceView: ALLC Ensembl:ENSG00000151360 euGenes: HUgn55821
    ECgene: ALLC Kegg: 55821 H-InvDB: ALLC

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for ALLC Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ALLC gene:
    Search GeneIP for patents involving ALLC

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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