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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ALKBH8 Gene

protein-coding   GIFtS: 49
GCID: GC11M107373

AlkB, Alkylation Repair Homolog 8 (E. Coli)

  Search for ALKBH8
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
AlkB, Alkylation Repair Homolog 8 (E. Coli)1 2     AlkB Homologue 82
ABH82 3 5     Alkylated DNA Repair Protein AlkB Homolog 82
Probable Alpha-Ketoglutarate-Dependent Dioxygenase ABH82 3     EC 1.14.11.-3
S-Adenosyl-L-Methionine-Dependent TRNA Methyltransferase ABH82 3     EC 2.1.1.2293
TRNA (Carboxymethyluridine(34)-5-O)-Methyltransferase ABH82 3     

External Ids:    HGNC: 251891   Entrez Gene: 918012   Ensembl: ENSG000001377607   OMIM: 6133065   UniProtKB: Q96BT73   

Export aliases for ALKBH8 gene to outside databases

Previous GC identifers: GC11M106879 GC11M103298


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ALKBH8 Gene: 
ALKBH8 (alkB, alkylation repair homolog 8 (E. coli)) is a protein-coding gene. GO annotations related to this gene include RNA binding and tRNA (uracil) methyltransferase activity. An important paralog of this gene is KIAA1456.

UniProtKB/Swiss-Prot: ALKB8_HUMAN, Q96BT7
Function: Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble
position of the anticodon loop in tRNA. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine
at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and
does not bind tRNA(Lys). Required for normal survival after DNA damage. May inhibit apoptosis and promote cell
survival and angiogenesis




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NT_033899.8  NC_018922.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ALKBH8 gene promoter:
         TBP   STAT1   Nkx2-2   CUTL1   Evi-1   GATA-6   POU2F1   POU2F1a   Msx-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidALKBH8 promoter sequence
   Search SABiosciences Chromatin IP Primers for ALKBH8

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ALKBH8


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q22.3   Ensembl cytogenetic band:  11q22.3   HGNC cytogenetic band: 11q22.3

ALKBH8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ALKBH8 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M107373:  view genomic region     (about GC identifiers)

Start:
107,373,452 bp from pter      End:
107,436,472 bp from pter
Size:
63,021 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ALKB8_HUMAN, Q96BT7 (See protein sequence)
Recommended Name: Alkylated DNA repair protein alkB homolog 8  
Size: 664 amino acids; 75208 Da
Subunit: Interacts with TRMT112
Subcellular location: Cytoplasm. Nucleus. Note=Predominantly cytoplasmic
3 PDB 3D structures from and Proteopedia for ALKBH8:
2CQ2 (3D)        3THP (3D)        3THT (3D)    
Secondary accessions: B1Q2M0 B4DEF6 Q8N989
Alternative splicing: 4 isoforms:  Q96BT7-1   Q96BT7-2   Q96BT7-3   Q96BT7-4   (May be due to competing donor splice site. No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ALKBH8: NX_Q96BT7

Explore proteomics data for ALKBH8 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96BT7

  • ALKBH8 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ALKBH8 Protein Expression
    REFSEQ proteins: NP_620130.2  
    ENSEMBL proteins: 
     ENSP00000415885   ENSP00000391225   ENSP00000374219   ENSP00000260318   ENSP00000397673  
     ENSP00000376812  

    Human Recombinant Protein Products for ALKBH8: 
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    Cloud-Clone Corp. Proteins for ALKBH8 

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0005829cytosol IDA--
    GO:0015630microtubule cytoskeleton IDA--

    ALKBH8 for ontologies           About GeneDecksing



    ALKBH8 Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ALKB: Alkylation repair homologs
    RBM: RNA binding motif (RRM) containing

    4 InterPro protein domains:
     IPR027450 AlkB-like
     IPR005123 Oxoglu/Fe-dep_dioxygenase
     IPR015095 AlkB_hom8_N
     IPR013216 Methyltransf_11

    Graphical View of Domain Structure for InterPro Entry Q96BT7

    ProtoNet protein and cluster: Q96BT7

    2 Blocks protein domains:
    IPB000504 RNA-binding region RNP-1 (RNA recognition motif)
    IPB001014 Ribosomal L23 protein


    UniProtKB/Swiss-Prot: ALKB8_HUMAN, Q96BT7
    Similarity: Belongs to the alkB family
    Similarity: Contains 1 Fe2OG dioxygenase domain
    Similarity: Contains 1 RRM (RNA recognition motif) domain


    ALKBH8 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ALKB8_HUMAN, Q96BT7
    Function: Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble
    position of the anticodon loop in tRNA. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine
    at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and
    does not bind tRNA(Lys). Required for normal survival after DNA damage. May inhibit apoptosis and promote cell
    survival and angiogenesis
    Catalytic activity: S-adenosyl-L-methionine + carboxymethyluridine(34) in tRNA = S-adenosyl-L-homocysteine +
    5-(2-methoxy-2-oxoethyl)uridine(34) in tRNA
    Induction: Up-regulated after DNA damage. Induction is mediated via ATM

         Enzyme Numbers (IUBMB): EC 1.14.11.-1 EC 2.1.1.2291

         Gene Ontology (GO): 5/9 molecular function terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding ----
    GO:0003676nucleic acid binding ----
    GO:0003723RNA binding IEA--
    GO:0005515protein binding IPI--
    GO:0008168methyltransferase activity ----
         
    ALKBH8 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for ALKBH8:
     Decreased POU5F1-GFP protein e  Decreased p24 protein expressi 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Alkbh8):
     normal 

    ALKBH8 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Alkbh8tm1Klng for ALKBH8

       inGenious Targeting Laboratory - Custom generated mouse model solutions for ALKBH8 
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    SwitchGear 3'UTR luciferase reporter plasmidALKBH8 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ALKBH8


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ALKBH8

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    3 Interacting proteins for ALKBH8 (Q96BT73 ENSP000003742194) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    FGFR3P226073I2D: score=1 
    TRMT112ENSP000003094334STRING: ENSP00000309433
    TRMT11ENSP000003339344STRING: ENSP00000333934
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006974response to DNA damage stimulus IDA--
    GO:0008152metabolic process ----
    GO:0030488tRNA methylation IDA--
    GO:0055114oxidation-reduction process ----

    ALKBH8 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ALKBH8 (ALKB8)

    Search CenterWatch for drugs/clinical trials and news about ALKBH8 / ALKB8

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ALKBH8 gene: 
    NM_138775.2  

    Unigene Cluster for ALKBH8:

    AlkB, alkylation repair homolog 8 (E. coli)
    Hs.503763  [show with all ESTs]
    Unigene Representative Sequence: NM_138775
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000428149(uc001pjk.3 uc010rvq.2 uc010rvr.2 uc009yxp.3 uc001pjl.3)
    ENST00000429370 ENST00000389568 ENST00000260318 ENST00000417449 ENST00000393100
    ENST00000530933
    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidALKBH8 3' UTR sequence
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    Additional mRNA sequence: 

    AB218768.1 AF086489.1 AK095523.1 AK293603.1 AK298800.1 AK304413.1 BC015183.1 BX649085.1 

    5 DOTS entries:

    DT.100016636  DT.108954  DT.40305950  DT.108955  DT.120738863 

    24/51 AceView cDNA sequences (see all 51):

    AA393087 BX109798 AA262405 AI925740 AA313350 BQ010516 AF086489 CK904381 
    BM753257 BM054706 NM_138775 BM054901 BG574178 AA411920 BX956410 AA806370 
    BC015183 AA336257 BG676898 AI590659 BE887937 CK904380 BX472466 BM839684 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for ALKBH8    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b
    SP1:                                                                          -     -               
    SP2:                                                                                                
    SP3:                                                                                                
    SP4:              -                                                                                 


    ECgene alternative splicing isoforms for ALKBH8

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ALKBH8 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCAATAAATT
    ALKBH8 Expression
    About this image


    See ALKBH8 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ALKBH8

    SOURCE GeneReport for Unigene cluster: Hs.503763

    UniProtKB/Swiss-Prot: ALKB8_HUMAN, Q96BT7
    Tissue specificity: Widely expressed, with highest expression in spleen, followed by pancreas and lung

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ALKBH8 gene from 8/19 species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Alkbh81 , 5 alkB, alkylation repair homolog 8 (E. coli)1, 5 81.1(n)1
    77.38(a)1
      9 (2.02 cM)5
    676671  NM_026303.11  NP_080579.11 
     33352315 
    chicken
    (Gallus gallus)
    Aves ALKBH81 alkB, alkylation repair homolog 8 (E. coli) 72.43(n)
    68.13(a)
      418972  XM_417166.3  XP_417166.3 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.178472 Transcribed sequence with weak similarity to protein more 74.86(n)    AL716387.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG178071 CG17807 50.91(n)
    47.62(a)
      37585  NM_137846.2  NP_611690.2 
    worm
    (Caenorhabditis elegans)
    Secernentea alkb-81 Protein ALKB-8 47.79(n)
    40.35(a)
      175476  NM_065350.3  NP_497751.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes TRM91 Trm9p 46.94(n)
    39.34(a)
      854994   NP_013698.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT1G363101 S-adenosylmethionine-dependent methyltransferase domain-containing more 46.07(n)
    37.54(a)
      840538  NM_103320.2  NP_564470.1 
    rice
    (Oryza sativa)
    Liliopsida Os02g07505001 hypothetical protein 48.05(n)
    38.97(a)
      4330741  NM_001054667.1  NP_001048132.1 


    ENSEMBL Gene Tree for ALKBH8 (if available)
    TreeFam Gene Tree for ALKBH8 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ALKBH8 gene
    KIAA14562  

    ALKBH8 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for ALKBH8
    PGOHUM00000245082


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1321 SNPs in ALKBH8 are shown (see all 1321)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs17891611,2
    C,F,H--107372953(+) attttA/Catttg 1 -- ds500111Minor allele frequency- C:0.47NA WA CSA EA 373
    rs1932600971,2
    --107373043(+) AACCTA/GAGGGT 1 -- ds50010--------
    rs1841169811,2
    --107373090(+) AGTGTC/GGGTGT 1 -- ds50010--------
    rs1895366551,2
    --107373122(+) TGTAGC/TTGGTG 1 -- ds50010--------
    rs616833431,2
    C,F--107373321(+) ATGGAC/TATTTG 1 -- ds50012Minor allele frequency- T:0.13WA 120
    rs1811451891,2
    --107373359(+) ACTGAC/TAACCC 1 -- ds50010--------
    rs766102041,2
    --107373435(+) AAGAAA/TGAGCA 1 -- ds50010--------
    rs1839175601,2
    --107373473(+) ATTTTC/TATTAT 1 -- ut310--------
    rs1886529061,2
    --107373478(+) TATTAC/TACAAT 1 -- ut310--------
    rs735516761,2
    C,F--107373508(+) TCACTT/CAATAC 1 -- ut313Minor allele frequency- C:0.20WA 122

    HapMap Linkage Disequilibrium report for ALKBH8 (107373452 - 107436472 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for ALKBH8:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv898376CNV Gain21882294
    nsv898373CNV Gain21882294
    dgv1312n71CNV Gain21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    ALKBH8 for disorders           About MalaCards
    OMIM gene information: 613306    OMIM disorders: --


    ALKBH8 for disorders           About GeneDecksing

    Genetic Association Database (GAD): ALKBH8
    Human Genome Epidemiology (HuGE) Navigator: ALKBH8 (1 document)

    Export disorders for ALKBH8 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ALKBH8 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with ALKBH8)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A novel human AlkB homologue, ALKBH8, contributes to human bladder cancer progression. (PubMed id 19293182)1, 2, 9 Shimada K.... Konishi N. (2009)
    2. Mammalian ALKBH8 possesses tRNA methyltransferase acti vity required for the biogenesis of multiple wobble uridine modifications implic ated in translational decoding. (PubMed id 20123966)1, 3 Songe-Moller L....Klungland A. (2010)
    3. Human AlkB homolog ABH8 is a tRNA methyltransferase required for wobble uridine modification and DNA damage survival. (PubMed id 20308323)1, 2 Fu D.... Samson L.D. (2010)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. ALKBH8-mediated formation of a novel diastereomeric pa ir of wobble nucleosides in mammalian tRNA. (PubMed id 21285950)1 van den Born E....Falnes P.O. (2011)
    6. Genetic associations of variants in genes encoding HI V-dependency factors required for HIV-1 infection. (PubMed id 21083371)4 Chinn L.W....O'Brien S.J. (2010)
    7. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    8. Expression and sub-cellular localization of human ABH family molecules. (PubMed id 17979886)2 Tsujikawa K....Yamamoto H. (2007)
    9. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
    10. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)2 Taylor T.D....Sakaki Y. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 91801 HGNC: 25189 AceView: LOC91801 Ensembl:ENSG00000137760 euGenes: HUgn91801
    ECgene: ALKBH8 H-InvDB: ALKBH8

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ALKBH8 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ALKBH8 gene:
    Search GeneIP for patents involving ALKBH8

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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