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ALKBH8 Gene

protein-coding   GIFtS: 49
GCID: GC11M107373

AlkB, Alkylation Repair Homolog 8 (E. Coli)

Pneumococci & Pneumococcal Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
AlkB, Alkylation Repair Homolog 8 (E. Coli)1 2     AlkB Homologue 82
ABH82 3 5     Alkylated DNA Repair Protein AlkB Homolog 82
Probable Alpha-Ketoglutarate-Dependent Dioxygenase ABH82 3     EC 1.14.11.-3
S-Adenosyl-L-Methionine-Dependent TRNA Methyltransferase ABH82 3     EC 2.1.1.2293
TRNA (Carboxymethyluridine(34)-5-O)-Methyltransferase ABH82 3     

External Ids:    HGNC: 251891   Entrez Gene: 918012   Ensembl: ENSG000001377607   OMIM: 6133065   UniProtKB: Q96BT73   

Export aliases for ALKBH8 gene to outside databases

Previous GC identifers: GC11M106879 GC11M103298


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ALKBH8 Gene:
ALKBH8 (alkB, alkylation repair homolog 8 (E. coli)) is a protein-coding gene. Diseases associated with ALKBH8 include hiv-1, and malaria. GO annotations related to this gene include RNA binding and tRNA (uracil) methyltransferase activity. An important paralog of this gene is KIAA1456.

UniProtKB/Swiss-Prot: ALKB8_HUMAN, Q96BT7
Function: Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble
position of the anticodon loop in tRNA. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine
at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and
does not bind tRNA(Lys). Required for normal survival after DNA damage. May inhibit apoptosis and promote cell
survival and angiogenesis




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000011.10  NT_033899.9  NC_018922.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ALKBH8 gene promoter:
         TBP   STAT1   Nkx2-2   CUTL1   Evi-1   GATA-6   POU2F1   POU2F1a   Msx-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidALKBH8 promoter sequence
   Search Chromatin IP Primers for ALKBH8

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ALKBH8


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q22.3   Ensembl cytogenetic band:  11q22.3   HGNC cytogenetic band: 11q22.3

ALKBH8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ALKBH8 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M107373:  view genomic region     (about GC identifiers)

Start:
107,373,452 bp from pter      End:
107,436,472 bp from pter
Size:
63,021 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: ALKB8_HUMAN, Q96BT7 (See protein sequence)
Recommended Name: Alkylated DNA repair protein alkB homolog 8  
Size: 664 amino acids; 75208 Da
Subunit: Interacts with TRMT112
3 PDB 3D structures from and Proteopedia for ALKBH8:
2CQ2 (3D)        3THP (3D)        3THT (3D)    
Secondary accessions: B1Q2M0 B4DEF6 Q8N989
Alternative splicing: 4 isoforms:  Q96BT7-1   Q96BT7-2   Q96BT7-3   Q96BT7-4   (May be due to competing donor splice site. No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ALKBH8: NX_Q96BT7

Explore proteomics data for ALKBH8 at MOPED


See ALKBH8 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_620130.2  
ENSEMBL proteins: 
 ENSP00000415885   ENSP00000391225   ENSP00000374219   ENSP00000260318   ENSP00000397673  
 ENSP00000376812  

ALKBH8 Human Recombinant Protein Products:

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Cloud-Clone Corp. CLIAs for ALKBH8


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
ALKB: Alkylation repair homologs
RBM: RNA binding motif (RRM) containing

4 InterPro protein domains:
 IPR013216 Methyltransf_11
 IPR027450 AlkB-like
 IPR005123 Oxoglu/Fe-dep_dioxygenase
 IPR015095 AlkB_hom8_N

Graphical View of Domain Structure for InterPro Entry Q96BT7

ProtoNet protein and cluster: Q96BT7

2 Blocks protein domains:
IPB000504 RNA-binding region RNP-1 (RNA recognition motif)
IPB001014 Ribosomal L23 protein


UniProtKB/Swiss-Prot: ALKB8_HUMAN, Q96BT7
Similarity: Belongs to the alkB family
Similarity: Contains 1 Fe2OG dioxygenase domain
Similarity: Contains 1 RRM (RNA recognition motif) domain


ALKBH8 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: ALKB8_HUMAN, Q96BT7
Function: Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble
position of the anticodon loop in tRNA. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine
at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and
does not bind tRNA(Lys). Required for normal survival after DNA damage. May inhibit apoptosis and promote cell
survival and angiogenesis
Catalytic activity: S-adenosyl-L-methionine + carboxymethyluridine(34) in tRNA = S-adenosyl-L-homocysteine +
5-(2-methoxy-2-oxoethyl)uridine(34) in tRNA
Induction: Up-regulated after DNA damage. Induction is mediated via ATM

     Enzyme Numbers (IUBMB): EC 1.14.11.-1 EC 2.1.1.2291

     Gene Ontology (GO): Selected molecular function terms (see all 9):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0000166nucleotide binding ----
GO:0003676nucleic acid binding ----
GO:0003723RNA binding IEA--
GO:0005515protein binding IPI--
GO:0008168methyltransferase activity ----
     
ALKBH8 for ontologies           About GeneDecksing


Phenotypes:
     2 GenomeRNAi human phenotypes for ALKBH8:
 Decreased POU5F1-GFP protein e  Decreased p24 protein expressi 

     1 MGI mutant phenotype (inferred from 1 allele(MGI details for Alkbh8):
 normal 

ALKBH8 for phenotypes           About GeneDecksing

Animal Models:
     MGI mouse knock-out Alkbh8tm1Klng for ALKBH8

   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ALKBH8
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6 qRT-PCR Assays for microRNAs that regulate ALKBH8:
hsa-miR-1244 hsa-miR-7-2* hsa-miR-7-1* hsa-miR-526b hsa-miR-205* hsa-miR-4282
SwitchGear 3'UTR luciferase reporter plasmidALKBH8 3' UTR sequence
Inhib. RNA
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Predesigned siRNA for gene silencing in human, mouse, rat ALKBH8

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(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
ALKB8_HUMAN, Q96BT7: Cytoplasm. Nucleus. Note=Predominantly cytoplasmic
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
cytosol5
nucleus5
cytoskeleton4

Gene Ontology (GO): 4 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus IDA--
GO:0005737cytoplasm ----
GO:0005829cytosol IDA--
GO:0015630microtubule cytoskeleton ----

ALKBH8 for ontologies           About GeneDecksing


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ALKBH8
Interactions:

    Search GeneGlobe Interaction Network for ALKBH8

STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

Selected Interacting proteins for ALKBH8 (Q96BT73 ENSP000003742194) via UniProtKB, MINT, STRING, and/or I2D (see all 12)
InteractantInteraction Details
GeneCardExternal ID(s)
FGFR3P226073I2D: score=1 
TRMT112ENSP000003094334STRING: ENSP00000309433
TRMT11ENSP000003339344STRING: ENSP00000333934
KARSENSP000003254484STRING: ENSP00000325448
N6AMT1ENSP000003035844STRING: ENSP00000303584
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Gene Ontology (GO): 4 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006974cellular response to DNA damage stimulus IDA--
GO:0008152metabolic process ----
GO:0030488tRNA methylation IDA--
GO:0055114oxidation-reduction process ----

ALKBH8 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for ALKBH8 (ALKB8)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for ALKBH8 gene: 
NM_138775.2  

Unigene Cluster for ALKBH8:

AlkB, alkylation repair homolog 8 (E. coli)
Hs.503763  [show with all ESTs]
Unigene Representative Sequence: NM_138775
7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000428149(uc001pjk.3 uc010rvq.2 uc010rvr.2 uc009yxp.3 uc001pjl.3)
ENST00000429370 ENST00000389568 ENST00000260318 ENST00000417449 ENST00000393100
ENST00000530933

miRNA
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6 qRT-PCR Assays for microRNAs that regulate ALKBH8:
hsa-miR-1244 hsa-miR-7-2* hsa-miR-7-1* hsa-miR-526b hsa-miR-205* hsa-miR-4282
SwitchGear 3'UTR luciferase reporter plasmidALKBH8 3' UTR sequence
Inhib. RNA
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Predesigned siRNA for gene silencing in human, mouse, rat ALKBH8
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  QuantiFast Probe-based Assays in human, mouse, rat ALKBH8

Additional mRNA sequence: 

AB218768.1 AF086489.1 AK095523.1 AK293603.1 AK298800.1 AK304413.1 BC015183.1 BX649085.1 

5 DOTS entries:

DT.100016636  DT.108954  DT.40305950  DT.108955  DT.120738863 

Selected AceView cDNA sequences (see all 51):

BG574178 BC015183 AA393087 BX109798 AA411920 BX956410 CK904381 NM_138775 
AA806370 AI925740 AF086489 AA262405 BM054901 BM054706 AA313350 BM753257 
BQ010516 BX472466 BM839684 AI590659 BG676898 CK904380 AA336257 BG573506 

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for ALKBH8    About this scheme

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b
SP1:                                                                          -     -               
SP2:                                                                                                
SP3:                                                                                                
SP4:              -                                                                                 


ECgene alternative splicing isoforms for ALKBH8

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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ALKBH8 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: CCAATAAATT
ALKBH8 Expression
About this image

ALKBH8 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

ALKBH8 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.503763

UniProtKB/Swiss-Prot: ALKB8_HUMAN, Q96BT7
Tissue specificity: Widely expressed, with highest expression in spleen, followed by pancreas and lung

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In Situ
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ALKBH8

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals and fungi.

Orthologs for ALKBH8 gene from Selected species (see all 19)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Alkbh81 , 5 alkB, alkylation repair homolog 8 (E. coli)1, 5 81.07(n)1
77.26(a)1
  9 (2.02 cM)5
676671  NM_026303.11  NP_080579.11 
 33352315 
chicken
(Gallus gallus)
Aves ALKBH81 alkB, alkylation repair homolog 8 (E. coli) 72.43(n)
68.13(a)
  418972  XM_004938828.1  XP_004938885.1 
tropical clawed frog
(Xenopus tropicalis)
Amphibia alkbh81 alkB, alkylation repair homolog 8 66.94(n)
66.18(a)
  550051  NM_001017297.3  NP_001017297.2 
zebrafish
(Danio rerio)
Actinopterygii Dr.178472 Transcribed sequence with weak similarity to protein more 74.86(n)    AL716387.1 
fruit fly
(Drosophila melanogaster)
Insecta CG178071 CG17807 53.1(n)
50.09(a)
  37585  NM_137846.2  NP_611690.2 
worm
(Caenorhabditis elegans)
Secernentea alkb-81 alkb-8 47.79(n)
40.53(a)
  175476  NM_065350.4  NP_497751.1 
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes TRM91 TRM9 47.79(n)
39.34(a)
  854994   NP_013698.1 


ENSEMBL Gene Tree for ALKBH8 (if available)
TreeFam Gene Tree for ALKBH8 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for ALKBH8 gene
KIAA14562  

ALKBH8 for paralogs           About GeneDecksing


1 Pseudogenes.org Pseudogene for ALKBH8
PGOHUM00000245082


(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for ALKBH8 (see all 1321)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 11 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs17891611,2
C,F,H--107372953(+) attttA/Catttg 1 -- ds500111Minor allele frequency- C:0.47NA WA CSA EA 373
rs1932600971,2
--107373043(+) AACCTA/GAGGGT 1 -- ds50010--------
rs1841169811,2
--107373090(+) AGTGTC/GGGTGT 1 -- ds50010--------
rs1895366551,2
--107373122(+) TGTAGC/TTGGTG 1 -- ds50010--------
rs616833431,2
C,F--107373321(+) ATGGAC/TATTTG 1 -- ds50012Minor allele frequency- T:0.13WA 120
rs1811451891,2
--107373359(+) ACTGAC/TAACCC 1 -- ds50010--------
rs766102041,2
--107373435(+) AAGAAA/TGAGCA 1 -- ds50010--------
rs1839175601,2
--107373473(+) ATTTTC/TATTAT 1 -- ut310--------
rs1886529061,2
--107373478(+) TATTAC/TACAAT 1 -- ut310--------
rs735516761,2
C,F--107373508(+) TCACTT/CAATAC 1 -- ut313Minor allele frequency- C:0.20WA 122

HapMap Linkage Disequilibrium report for ALKBH8 (107373452 - 107436472 bp)

Structural Variations
     Database of Genomic Variants (DGV) 3 variations for ALKBH8:    About this table    
Variant IDTypeSubtypePubMed ID
nsv898376CNV Gain21882294
nsv898373CNV Gain21882294
dgv1312n71CNV Gain21882294

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing ALKBH8
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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 613306    OMIM disorders: --

2 diseases for ALKBH8:    
About MalaCards
hiv-1    malaria


ALKBH8 for disorders           About GeneDecksing


Congresses - knowledge worth sharing:
The International Symposium on Pneumococci and Pneumococcal Diseases (ISPPD) 9 - 13 March 2014
Genetic Association Database (GAD): ALKBH8
Human Genome Epidemiology (HuGE) Navigator: ALKBH8 (1 document)

Export disorders for ALKBH8 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for ALKBH8 gene, integrated from 10 sources (see all 13):
(articles sorted by number of sources associating them with ALKBH8)
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  1. A novel human AlkB homologue, ALKBH8, contributes to human bladder cancer progression. (PubMed id 19293182)1, 2, 9 Shimada K.... Konishi N. (Cancer Res. 2009)
  2. Mammalian ALKBH8 possesses tRNA methyltransferase activity required for the biogenesis of multiple wobble uridine modifications implicated in translational decoding. (PubMed id 20123966)1, 3 Songe-MA...Klungland A. (Mol. Cell. Biol. 2010)
  3. Human AlkB homolog ABH8 is a tRNA methyltransferase required for wobble uridine modification and DNA damage survival. (PubMed id 20308323)1, 2 Fu D.... Samson L.D. (Mol. Cell. Biol. 2010)
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
  5. ALKBH8-mediated formation of a novel diastereomeric pair of wobble nucleosides in mammalian tRNA. (PubMed id 21285950)1 van den Born E....Falnes P.A.9. (Nat Commun 2011)
  6. Genetic associations of variants in genes encoding HIV-dependency factors required for HIV-1 infection. (PubMed id 21083371)4 Chinn L.W....O'Brien S.J. (J. Infect. Dis. 2010)
  7. Identification of host proteins required for HIV infection through a functional genomic screen. (PubMed id 18187620)1 Brass A.L....Elledge S.J. (Science 2008)
  8. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
  9. Expression and sub-cellular localization of human ABH family molecules. (PubMed id 17979886)2 Tsujikawa K.... Yamamoto H. (J. Cell. Mol. Med. 2007)
  10. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 91801 HGNC: 25189 AceView: LOC91801 Ensembl:ENSG00000137760 euGenes: HUgn91801
ECgene: ALKBH8 H-InvDB: ALKBH8

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for ALKBH8 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for ALKBH8 gene:
Search GeneIP for patents involving ALKBH8

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