Aliases for ALKBH4 Gene
External Ids for ALKBH4 Gene
Previous GeneCards Identifiers for ALKBH4 Gene
GeneCards Summary for ALKBH4 Gene
ALKBH4 (AlkB Homolog 4, Lysine Demthylase) is a Protein Coding gene. GO annotations related to this gene include actin binding and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors.
UniProtKB/Swiss-Prot for ALKBH4 Gene
Dioxygenase that mediates demethylation of actin monomethylated at Lys-84 (K84me1), thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. May be involved in transcription regulation.