ALKBH1 Gene
protein-coding GIFtS: 49
GCID: GC14M078138
|
|
alkB, alkylation repair homolog 1 (E. coli)(Previous names: alkB, alkylation repair homolog (E. coli) )
(Previous symbol: ALKBH)
| |
Aliases
for ALKBH1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| AlkB, Alkylation Repair Homolog 1 (E. Coli)1 2 | | DNA Oxidative Demethylase ALKBH12 3 | | ABH1 2 3 | | AlkB, Alkylation Repair Homolog (E. Coli)1 | | ALKBH1 2 3 | | Alkylated DNA Repair Protein AlkB Homolog 12 | | AlkB1 | | Alkylation Repair, AlkB Homolog2 | | HABH1 | | EC 1.14.11.333 | | Alpha-Ketoglutarate-Dependent Dioxygenase ABH12 3 | | EC 4.2.99.183 | | ABH12 3 | | ALKB5 | | DNA Lyase ABH12 3 | | |
Export aliases for ALKBH1 gene to outside databasesPrevious GC identifers: GC14M077208 GC14M058306 |
Summaries
for ALKBH1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ALKBH1:
This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive responsemechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of1-methyladenine and 3-methylcytosine. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: ALKB1_HUMAN, Q13686Function: Dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidativedemethylation. Requires molecular oxygen, alpha-ketoglutarate and iron. May have a role in placental trophoblastlineage differentiation (By similarity). Has DNA lyase activity and introduces double-stranded breaks at abasic sites.Cleaves both single-stranded DNA and double-stranded DNA at abasic sites, with the greatest activity towardsdouble-stranded DNA with two abasic sites. DNA lyase activity does not require alpha-ketoglutarate and iron
|
Genomic Views
for ALKBH1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000014.8 NC_018925.1 NT_026437.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ALKBH1 gene promoter:
ER-alpha Elk-1 POU3F2 (N-Oct-5a) POU3F2 (N-Oct-5b) Nkx2-5 POU3F2 FOXL1 C/EBPalpha CHOP-10
Other transcription factors
Search SABiosciences Chromatin IP Primers for ALKBH1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ALKBH1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 14q24.3 Ensembl cytogenetic band: 14q24.3 HGNC cytogenetic band: 14q24ALKBH1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 14 GeneLoc Exon Structure GeneLoc location for GC14M078138: view genomic region
(about GC identifiers)
Start:
|
78,138,747 bp from pter |
End:
|
78,174,363 bp from pter |
Size:
|
35,617 bases |
Orientation:
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minus strand |
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Proteins
for ALKBH1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ALKB1_HUMAN, Q13686 (See
protein sequence)Recommended Name: Alkylated DNA repair protein alkB homolog 1 Size: 389 amino acids; 43832 Da
Cofactor: Binds 1 Fe(2+) ion per subunit
Subunit: Monomer. Interacts with DNAJB6 (By similarity)
Subcellular location: Mitochondrion. Nucleus (By similarity). Note=Mainly localizes in euchromatin, largely excludedfrom heterochromatin and nucleoli (By similarity)
Caution: Detected in cytoplasm and nucleus When expressed as fusion protein with an N-terminal tag, or when the first26 N-terminal residues are removed (PubMed:17979886 and PubMed:18603530). The endogenous, unmodified protein localizesto mitochondria (PubMed:18603530)
Sequence caution: Sequence=CAA63047.1; Type=Frameshift; Positions=Several;
Secondary accessions: Q8TAU1 Q9ULA7Explore the universe of human proteins at neXtProt for ALKBH1: NX_Q13686
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q13686
ALKBH1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_006011.2
ENSEMBL proteins: ENSP00000216489 ENSP00000451886 ENSP00000451386
Human Recombinant Protein Products for ALKBH1:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
ALKBH1 for ontologies About GeneDecksing
ALKBH1 Antibody Products:
Assay Products for ALKBH1: |
Protein
Domains /
Families
for ALKBH1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ALKBH1 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q13686ProtoNet protein and cluster: Q13686 UniProtKB/Swiss-Prot: ALKB1_HUMAN, Q13686Similarity: Belongs to the alkB familySimilarity: Contains 1 Fe2OG dioxygenase domain |
Function
for ALKBH1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: ALKB1_HUMAN, Q13686Function: Dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidativedemethylation. Requires molecular oxygen, alpha-ketoglutarate and iron. May have a role in placental trophoblastlineage differentiation (By similarity). Has DNA lyase activity and introduces double-stranded breaks at abasic sites.Cleaves both single-stranded DNA and double-stranded DNA at abasic sites, with the greatest activity towardsdouble-stranded DNA with two abasic sites. DNA lyase activity does not require alpha-ketoglutarate and ironCatalytic activity: The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-eliminationreaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphateCatalytic activity: DNA-base-CH(3) + 2-oxoglutarate + O(2) = DNA-base + formaldehyde + succinate + CO(2) Enzyme Numbers (IUBMB): EC 1.14.11.331 EC 4.2.99.181
Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003906 | DNA-(apurinic or apyrimidinic site) lyase activity |
IDA | 19959401 | | GO:0005515 | protein binding |
-- | -- | | GO:0008198 | ferrous iron binding |
IDA | 18603530 | | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen |
IEA | -- | | GO:0042056 | chemoattractant activity |
IEA | -- |
ALKBH1 for ontologies About GeneDecksing
Phenotypes:
11 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Alkbh1):
ALKBH1 for phenotypes About GeneDecksing
Animal Models:
Mouse knock-outs for ALKBH1: Alkbh1tm1.1Lpkn Alkbh1tm1Klng
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ALKBH1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ALKBH1 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ALKBH1 (NM_006020) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ALKBH1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ALKBH1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ALKBH1 |
|
Pathways & Interactions
for ALKBH1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Integrated Breast Cancer Pathway | |
1  BioSystems Pathway for ALKBH1
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ALKBH1
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
2 Interacting proteins for ALKBH1 (Q136863 ENSP000002164894) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 5/15 biological process terms (GO ID links to tree view) (see all 15): About this table
ALKBH1 for ontologies About GeneDecksing
|
Drugs & Compounds
for ALKBH1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
ALKBH1 for compounds About GeneDecksing
 Browse Tocris compounds for ALKBH1
10 Novoseek chemical compound relationships for ALKBH1 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| 3-methylcytosine |
97.9 |
6 |
15576352 (2), 12594517 (1), 17979886 (1), 19852088 (1) |
| 1-methyladenine |
94.7 |
8 |
12944387 (2), 15576352 (2), 12594517 (1), 17979886 (1) (see all 5) |
| alpha-ketoglutarate |
73 |
5 |
19852088 (1), 16469386 (1), 17979886 (1), 12486230 (1) |
| hexadecane |
69.4 |
1 |
7804909 (1) |
| methylnitrosourea |
58.2 |
2 |
16358713 (1) |
| naphthalene |
54.9 |
4 |
7804909 (2), 18592409 (1), 11375152 (1) |
| methylmethanesulfonate |
47.4 |
6 |
10950872 (3), 8600462 (2) |
| formaldehyde |
37.4 |
2 |
19852088 (1), 12486230 (1) |
| oxygen |
15.6 |
1 |
19852088 (1) |
| carbon |
0 |
1 |
11418560 (1) |
Search CenterWatch for drugs/clinical trials and news about ALKBH1 / ALKB1
|
Transcripts
for ALKBH1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ALKBH1 gene (2 alternative transcripts): NM_006020.2 NM_001039506.1 Unigene Cluster for ALKBH1: AlkB, alkylation repair homolog 1 (E. coli) Hs.94542 [show with all ESTs]Unigene Representative Sequence: NM_0060204 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000216489(uc001xuc.1) ENST00000557057 ENST00000555100 ENST00000554097
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ALKBH1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ALKBH1 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ALKBH1 (NM_006020) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ALKBH1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ALKBH1 |
Additional cDNA sequence: BC015024.1 BC025787.1 X91992.1 6 DOTS entries: DT.95269865 DT.108343 DT.110436 DT.100843274 DT.92420358 DT.95269867 24/72 AceView cDNA sequences (see all 72): BM726581 CR604550 BE552451 BF194721 BF057641 BM726354 AI668640 N79558 BF062252 N77150 BI822148 AA811353 AI368879 AA298689 BF963468 BE873425 BC015024 CB992340 AI572185 AI246473 BX105183 NM_006020 AW794512 BQ709174
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for ALKBH1 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | · | 6d |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | - | | | | - | | | | | | | | | | | | |
| SP4: | | | | | | | - | | - | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ALKBH1
|
Expression
for ALKBH1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ALKBH1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AATAAACTCA
About this image
See ALKBH1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ALKBH1
SOURCE GeneReport for Unigene cluster: Hs.94542
UniProtKB/Swiss-Prot: ALKB1_HUMAN, Q13686Tissue specificity: Ubiquitous
SABiosciences Custom PCR Arrays for ALKBH1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ALKBH1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ALKBH1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ALKBH1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ALKBH1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ALKBH1 |
Orthologs
for ALKBH1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for ALKBH1 gene from 10/30 species (see all 30) About this table
ENSEMBL Gene Tree for ALKBH1 (if available)
TreeFam Gene Tree for ALKBH1 (if available) |
Paralogs
for ALKBH1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for ALKBH1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 14 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ALKBH1 (78138747 - 78174363 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 5 variations for ALKBH1
4 CNVs: 3943 76681 3056 8773
1 Indel: 33587 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ALKBH1 |
|
Disorders
/ Diseases
for ALKBH1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ALKBH1 for disorders About GeneDecksing
OMIM gene information: 605345
OMIM disorders: --
1  disease for ALKBH1: About MalaCardsneuronitis
1 Novoseek disease relationship for ALKBH1 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| cancer |
0 |
1 |
19293182 (1) |
Export disorders for ALKBH1 gene to outside databases
|
Publications
for ALKBH1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ALKBH1 gene, integrated from 9 sources (see all 55):
(articles sorted by number of sources associating them with ALKBH1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular cloning and functional analysis of a human cDNA encoding an Escherichia coli AlkB homolog, a protein involved in DNA alkylation damage repair. (PubMed id 8600462)1, 2, 3, 9 Wei Y.F.... Shell B.K. (1996)
- Human AlkB homologue 1 (ABH1) exhibits DNA lyase acti vity at abasic sites. (PubMed id 19959401)1, 2, 9 MA1ller T.A....Hausinger R.P. (2010)
- Human AlkB homolog 1 is a mitochondrial protein that demethylates 3-methylcytosine in DNA and RNA. (PubMed id 18603530)1, 2 Westbye M.P....Krokan H.E. (2008)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence and analysis of human chromosome 14. (PubMed id 12508121)1, 2 Heilig R.... Weissenbach J. (2003)
- Expression and sub-cellular localization of human ABH family molecules. (PubMed id 17979886)2, 9 Tsujikawa K....Yamamoto H. (2007)
- Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA. (PubMed id 12594517)1, 9 Aas P.A....Krokan H.E. (2003)
- Genome-wide association study of prognosis in advanced non-small cell lung cancer patients receiving platinum-based chemotherapy. (PubMed id 22872573)1 Hu L....Shen H. (2012)
- Homology modeling and function prediction of hABH1, in volving in repair of alkylation damaged DNA. (PubMed id 21956739)1 Shankaracharya ....Vidyarthi A.S. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
|
External Searches for ALKBH1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ALKBH1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ALKBH1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ALKBH1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ALKBH1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ALKBH1 gene:
Search GeneIP for patents involving ALKBH1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ALKBH1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for ALKBH1 | | OriGene shRNA RFP for ALKBH1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ALKBH1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ALKBH1 | | | OriGene Protein Over-expression Lysate for ALKBH1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ALKBH1 | | OriGene 3'-UTR Clone for ALKBH1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ALKBH1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ALKBH1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for ALKBH1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ALKBH1 | | OriGene Custom Protein Services for ALKBH1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ALKBH1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ALKBH1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ALKBH1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ALKBH1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ALKBH1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ALKBH1 |
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| | | | Search Tocris compounds for ALKBH1 |
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 | | | ALKBH1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ALKBH1 |
|  |  |  |  | | | | ThermoFisher Antibodies for ALKBH1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ALKBH1 |
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