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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ALG5 Gene

protein-coding   GIFtS: 56
GCID: GC13M037523

ALG5, Dolichyl-Phosphate Beta-Glucosyltransferase

(Previous names: asparagine-linked glycosylation 5 homolog (yeast, dolichyl-phosphate...)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
ALG5, Dolichyl-Phosphate Beta-Glucosyltransferase1 2     Asparagine-Linked Glycosylation 5, Dolichyl-Phosphate
Beta-Glucosyltransferase Homolog2
Asparagine-Linked Glycosylation 5 Homolog (Yeast, Dolichyl-Phosphate
Beta-Glucosyltransferase)1 2
     bA421P11.22
Asparagine-Linked Glycosylation Protein 5 Homolog2 3     dolP-glucosyltransferase2
EC 2.4.1.1173 8     Dolichyl Phosphate Glucosyltransferase2
Asparagine-Linked Glycosylation 5, Dolichyl-Phosphate
Beta-Glucosyltransferase Homolog (S. Cerevisiae)1
     Dolichyl-Phosphate Beta-Glucosyltransferase2
RP11-421P11.22     DolP-glucosyltransferase3
Alg5, S. Cerevisiae, Homolog Of2     EC 2.4.18
Asparagine-Linked Glycosylation 5 Homolog (S. Cerevisiae,
Dolichyl-Phosphate Beta-Glucosyltransferase)2
     

External Ids:    HGNC: 202661   Entrez Gene: 298802   Ensembl: ENSG000001206977   OMIM: 6045655   UniProtKB: Q9Y6733   

Export aliases for ALG5 gene to outside databases

Previous GC identifers: GC13M035510 GC13M031510 GC13M036460 GC13M035321 GC13M036421 GC13M018335


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ALG5 Gene:
This gene encodes a member of the glycosyltransferase 2 family. The encoded protein participates in glucosylation
of the oligomannose core in N-linked glycosylation of proteins. The addition of glucose residues to the
oligomannose core is necessary to ensure substrate recognition, and therefore, effectual transfer of the
oligomannose core to the nascent glycoproteins. Multiple transcript variants encoding different isoforms have
been found for this gene. (provided by RefSeq, Nov 2008)

GeneCards Summary for ALG5 Gene: 
ALG5 (ALG5, dolichyl-phosphate beta-glucosyltransferase) is a protein-coding gene. Diseases associated with ALG5 include congenital disorder of glycosylation, and among its related super-pathways are WNT ligand biogenesis and trafficking and Synthesis of substrates in N-glycan biosythesis. GO annotations related to this gene include oligosaccharyl transferase activity and dolichyl-phosphate beta-glucosyltransferase activity.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000013.10  NT_024524.14  NC_018924.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ALG5 gene promoter:
         GR   GR-beta   Lmo2   Tal-1beta   MEF-2A   GR-alpha   aMEF-2   ITF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidALG5 promoter sequence
   Search SABiosciences Chromatin IP Primers for ALG5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ALG5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q13.3   Ensembl cytogenetic band:  13q13.3   HGNC cytogenetic band: 13q13.1

ALG5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ALG5 gene location

GeneLoc information about chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13M037523:  view genomic region     (about GC identifiers)

Start:
37,523,907 bp from pter      End:
37,574,398 bp from pter
Size:
50,492 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ALG5_HUMAN, Q9Y673 (See protein sequence)
Recommended Name: Dolichyl-phosphate beta-glucosyltransferase  
Size: 324 amino acids; 36946 Da
Subcellular location: Endoplasmic reticulum membrane; Single-pass type II membrane protein (By similarity)
Secondary accessions: B4DR37 Q5TBA6
Alternative splicing: 2 isoforms:  Q9Y673-1   Q9Y673-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ALG5: NX_Q9Y673

Explore proteomics data for ALG5 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9Y673

  • 2 DME Specific Peptides for ALG5 (Q9Y673)
     VPSYNEE  DTQCGFKL 

    ALG5 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ALG5 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001135836.1  NP_037470.1  

    ENSEMBL proteins: 
     ENSP00000239891   ENSP00000390533   ENSP00000389647  
    Reactome Protein details: Q9Y673
    Human Recombinant Protein Products for ALG5: 
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    Cloud-Clone Corp. Proteins for ALG5 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005789endoplasmic reticulum membrane TAS--
    GO:0016021integral to membrane IEA--

    ALG5 for ontologies           About GeneDecksing



    ALG5 Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    GLT2: Glycosyltransferase family 2 domain containing

    1 InterPro protein domain:
     IPR001173 Glyco_trans_2

    Graphical View of Domain Structure for InterPro Entry Q9Y673

    ProtoNet protein and cluster: Q9Y673

    1 Blocks protein domain: IPB001173 Glycosyl transferase

    UniProtKB/Swiss-Prot: ALG5_HUMAN, Q9Y673
    Similarity: Belongs to the glycosyltransferase 2 family


    ALG5 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ALG5_HUMAN, Q9Y673
    Catalytic activity: UDP-glucose + dolichyl phosphate = UDP + dolichyl beta-D-glucosyl phosphate

         Enzyme Numbers (IUBMB): EC 2.4.1.1171 2 EC 2.4.12

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004576oligosaccharyl transferase activity TAS10359825
    GO:0004581dolichyl-phosphate beta-glucosyltransferase activity IEA--
    GO:0016757transferase activity, transferring glycosyl groups ----
         
    ALG5 for ontologies           About GeneDecksing


    Phenotypes:
         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Alg5):
     embryogenesis  mortality/aging 

    ALG5 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ALG5 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ALG5 
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    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for ALG5 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Asparagine N-linked glycosylation
    Asparagine N-linked glycosylation0.77
    N-Glycan biosynthesis0.52
    WNT ligand biogenesis and trafficking0.77
    Post-translational protein modification0.44
    Signaling by Wnt0.62
    Metabolism of proteins0.35
    2Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
    Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein0.53
    dolichyl-diphosphooligosaccharide biosynthesis0.30
    Synthesis of substrates in N-glycan biosythesis0.53
    3Signaling by GPCR
    Signal Transduction0.55
    4Metabolism
    Metabolic pathways0.40
    5Synthesis of dolichyl-phosphate-glucose
    Synthesis of dolichyl-phosphate-glucose

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 BioSystems Pathway for ALG5
        dolichyl-diphosphooligosaccharide biosynthesis


    5/9        Reactome Pathways for ALG5 (see all 9)
        Synthesis of substrates in N-glycan biosythesis
    Signaling by Wnt
    Asparagine N-linked glycosylation
    Signal Transduction
    Metabolism of proteins


    2         Kegg Pathways  (Kegg details for ALG5):
        N-Glycan biosynthesis
    Metabolic pathways

    UniProtKB/Swiss-Prot: ALG5_HUMAN, Q9Y673
    Pathway: Protein modification; protein glycosylation


    ALG5 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ALG5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/84 Interacting proteins for ALG5 (Q9Y6733 ENSP000002398914) via UniProtKB, MINT, STRING, and/or I2D (see all 84)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    ACER3Q9NUN73, ENSP000002785444I2D: score=4 STRING: ENSP00000278544
    DDOSTP396563, ENSP000003641884I2D: score=3 STRING: ENSP00000364188
    PIGKQ926433, ENSP000003598484I2D: score=2 STRING: ENSP00000359848
    RPN1P048433, ENSP000002962554I2D: score=2 STRING: ENSP00000296255
    ALG12Q9BV103, ENSP000003338134I2D: score=1 STRING: ENSP00000333813
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006486protein glycosylation TAS10359825
    GO:0006488dolichol-linked oligosaccharide biosynthetic process TAS--
    GO:0007368determination of left/right symmetry IEA--
    GO:0018279protein N-linked glycosylation via asparagine TAS--
    GO:0043687post-translational protein modification TAS--

    ALG5 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ALG5

    4 HMDB Compounds for ALG5    About this table
    CompoundSynonyms CAS #PubMed Ids
    Dolichol phosphatedolichol-phosphate (see all 6)34457-14-2--
    Dolichyl b-D-glucosyl phosphateDolichol monophosphate glucose (see all 10)220496-27-5--
    Uridine 5'-diphosphate5'-UDP (see all 9)58-98-0--
    Uridine diphosphate glucose(UPD)-glucose (see all 24)133-89-1--

    Search CenterWatch for drugs/clinical trials and news about ALG5

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ALG5 gene (2 alternative transcripts): 
    NM_001142364.1  NM_013338.4  

    Unigene Cluster for ALG5:

    ALG5, dolichyl-phosphate beta-glucosyltransferase
    Hs.507769  [show with all ESTs]
    Unigene Representative Sequence: AK097252
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000239891(uc001uvy.3 uc010ter.2) ENST00000486410 ENST00000460230
    ENST00000496689 ENST00000443765(uc010teq.2) ENST00000413537
    miRNA
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    Additional mRNA sequence: 

    AF088028.1 AF161498.1 AF183413.1 AK097252.1 AK299085.1 BC012531.1 HM245395.1 

    14 DOTS entries:

    DT.215118  DT.100819579  DT.100819581  DT.95172124  DT.95204467  DT.101966659  DT.95123802  DT.100819578 
    DT.102836936  DT.97858894  DT.95204472  DT.95204487  DT.120794453  DT.435228 

    24/146 AceView cDNA sequences (see all 146):

    CR625593 AA534499 W70281 AL525209 NM_013338 BU683287 BG000502 BE502329 
    AV725253 AI093199 BQ015269 AA534740 AI769938 CA428354 CB989866 AW183072 
    CA436929 CA449651 BM548894 BM717294 BM069666 BM982043 BQ957664 AL701917 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for ALG5    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b
    SP1:                                                  -                           
    SP2:        -           -                                                         
    SP3:                                                                              


    ECgene alternative splicing isoforms for ALG5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ALG5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TATGGGTTCC
    ALG5 Expression
    About this image


    See ALG5 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ALG5

    SOURCE GeneReport for Unigene cluster: Hs.507769

    UniProtKB/Swiss-Prot: ALG5_HUMAN, Q9Y673
    Tissue specificity: Expressed in pancreas, placenta, liver, heart, brain, kidney, skeletal muscle, and lung

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ALG5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ALG5 gene from 10/24 species (see all 24)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Alg51 , 5 asparagine-linked glycosylation 5 homolog (yeast, dolichyl-phosphate more5
    asparagine-linked glycosylation 5 (dolichyl-phosphate more1
    86.75(n)1
    90.06(a)1
      3 (25.60 cM)5
    662481  NM_025442.31  NP_079718.11 
     547355395 
    chicken
    (Gallus gallus)
    Aves ALG51 asparagine-linked glycosylation 5, dolichyl-phosphate more 76.88(n)
    80.5(a)
      418898  XM_417093.3  XP_417093.2 
    lizard
    (Anolis carolinensis)
    Reptilia ALG56
    Uncharacterized protein
    77(a)
    1 ↔ 1
    2(82552997-82574280)
    African clawed frog
    (Xenopus laevis)
    Amphibia alg5-prov2 Alg5, S. cerevisiae, homolog of 76.67(n)    BC044127.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufk42e012 Transcribed sequence with moderate similarity to protein more 75.97(n)    57084317 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG78703
    wol1
    dolichyl-phosphate
    beta-glucosyltransferase3
    wollknaeuel1
    60(a)3
    57.07(n)1
    59.22(a)1
      29A33
    341341  NM_135358.11  NP_609202.11 
    worm
    (Caenorhabditis elegans)
    Secernentea H43I07.31 , 3 Protein H43I07.31 43(a)3
    52.14(n)1
    45.51(a)1
      V(4195430-4198906)3
    1788221  NM_171446.21  NP_741523.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes ALG5(YPL227C)4
    ALG51
    UDP-glucose:dolichyl-phosphate glucosyltransferase, more4
    Alg5p1
    51.36(n)1
    42.52(a)1
      16(121167-120163)4
    8558741, 4  NP_015097.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G396301 dolichyl-phosphate beta-glucosyltransferase 57.38(n)
    51.15(a)
      818546  NM_129519.4  NP_181493.1 
    rice
    (Oryza sativa)
    Liliopsida Os.46412 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 76.22(n)    NM_185170.1 


    ENSEMBL Gene Tree for ALG5 (if available)
    TreeFam Gene Tree for ALG5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/908 SNPs in ALG5 are shown (see all 908)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 13 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1845285671,2
    --37523471(+) ACTCCC/TTCCAT 2 -- ds50010--------
    rs1890566561,2
    --37523502(+) GGCACA/GATCAT 2 -- ds50010--------
    rs1444532091,2
    C--37523668(+) AATAGA/GTTTCT 2 -- ds50010--------
    rs1394053311,2
    --37523797(+) TAGGGA/TAAGAA 2 -- ds50010--------
    rs1129361821,2
    F--37523805(+) GAATAG/ACTTCT 2 -- ds50011Minor allele frequency- A:0.50CSA 2
    rs1180681421,2
    C,F--37523811(+) CTTCTG/TTCTAC 2 -- ds50011Minor allele frequency- T:0.02NA 120
    rs1873547871,2
    --37523872(+) AGAAAA/CTCTGA 2 -- ds50010--------
    rs1124513841,2
    F--37523942(+) CTTATG/TGAAAG 2 -- ut311Minor allele frequency- T:0.50CSA 4
    rs1451418071,2
    C--37524047(+) CTGAAC/GCATAA 2 -- ut310--------
    rs2006015991,2
    --37524052(+) GCATAA/GGAACA 2 -- ut310--------

    HapMap Linkage Disequilibrium report for ALG5 (37523907 - 37574398 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for ALG5:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2454960CNV Deletion19546169
    esv272243CNV Insertion20981092
    esv267708CNV Insertion20981092
    nsv522336CNV Gain19592680

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 604565    OMIM disorders: --

    2 diseases for ALG5:    About MalaCards
    congenital disorder of glycosylation    

    1 disease from the University of Copenhagen DISEASES database for ALG5:
    Congenital disorder of glycosylation

    ALG5 for disorders           About GeneDecksing


    Export disorders for ALG5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ALG5 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with ALG5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A mutation in the human ortholog of the Saccharomyces cerevisiae ALG6 gene causes carbohydrate-deficient glycoprotein syndrome type-Ic. (PubMed id 10359825)1, 2, 3, 9 Imbach T....Hennet T. (1999)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (2000)
    4. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    6. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    7. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)1 Suzuki Y.... Sugano S. (2004)
    8. The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)2 Dunham A.... Ross M.T. (2004)
    9. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 29880 HGNC: 20266 AceView: ALG5 Ensembl:ENSG00000120697 euGenes: HUgn29880
    ECgene: ALG5 Kegg: 29880 H-InvDB: ALG5

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ALG5 Pharmacogenomics, SNPs, Pathways
    GGDBhttp://riodb.ibase.aist.go.jp/rcmg/ggdb/

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ALG5 gene:
    Search GeneIP for patents involving ALG5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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