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Aliases for ALG1L2 Gene

Aliases for ALG1L2 Gene

  • ALG1, Chitobiosyldiphosphodolichol Beta-Mannosyltransferase-Like 2 2 3
  • Asparagine-Linked Glycosylation 1-Like 2 2
  • EC 2.4.1.- 4

External Ids for ALG1L2 Gene

Summaries for ALG1L2 Gene

GeneCards Summary for ALG1L2 Gene

ALG1L2 (ALG1, Chitobiosyldiphosphodolichol Beta-Mannosyltransferase-Like 2) is a Protein Coding gene. GO annotations related to this gene include transferase activity, transferring glycosyl groups.

UniProtKB/Swiss-Prot for ALG1L2 Gene

  • Putative glycosyltransferase.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ALG1L2 Gene

Genomics for ALG1L2 Gene

Genomic Location for ALG1L2 Gene

Start:
130,081,831 bp from pter
End:
130,113,227 bp from pter
Size:
31,397 bases
Orientation:
Plus strand

Genomic View for ALG1L2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ALG1L2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ALG1L2 Gene

No data available for Regulatory Elements for ALG1L2 Gene

Proteins for ALG1L2 Gene

  • Protein details for ALG1L2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    C9J202-AG1L2_HUMAN
    Recommended name:
    Putative glycosyltransferase ALG1L2
    Protein Accession:
    C9J202
    Secondary Accessions:

    Protein attributes for ALG1L2 Gene

    Size:
    215 amino acids
    Molecular mass:
    24154 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ALG1L2 Gene

Proteomics data for ALG1L2 Gene at MOPED

Post-translational modifications for ALG1L2 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys14

Other Protein References for ALG1L2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ALG1L2 Gene

Domains for ALG1L2 Gene

Gene Families for ALG1L2 Gene

HGNC:
  • GLT1 :Glycosyltransferase group 1 domain containing

Protein Domains for ALG1L2 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

AG1L2_HUMAN
Family:
  • Belongs to the glycosyltransferase group 1 family.:
    • C9J202
genes like me logo Genes that share domains with ALG1L2: view

Function for ALG1L2 Gene

Molecular function for ALG1L2 Gene

UniProtKB/Swiss-Prot Function: Putative glycosyltransferase.

Enzyme Numbers (IUBMB) for ALG1L2 Gene

Gene Ontology (GO) - Molecular Function for ALG1L2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016757 transferase activity, transferring glycosyl groups IEA --
genes like me logo Genes that share ontologies with ALG1L2: view

Phenotypes for ALG1L2 Gene

GenomeRNAi human phenotypes for ALG1L2:
genes like me logo Genes that share phenotypes with ALG1L2: view

No data available for Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ALG1L2 Gene

Localization for ALG1L2 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ALG1L2 Gene COMPARTMENTS Subcellular localization image for ALG1L2 gene
Compartment Confidence
mitochondrion 2
cytosol 1
endoplasmic reticulum 1
nucleus 1

No data available for Gene Ontology (GO) - Cellular Components for ALG1L2 Gene

Pathways for ALG1L2 Gene

SuperPathways for ALG1L2 Gene

No Data Available

Interacting Proteins for ALG1L2 Gene

Gene Ontology (GO) - Biological Process for ALG1L2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008152 metabolic process IEA --
GO:0009058 biosynthetic process --
genes like me logo Genes that share ontologies with ALG1L2: view

No data available for Pathways by source for ALG1L2 Gene

Transcripts for ALG1L2 Gene

mRNA/cDNA for ALG1L2 Gene

(2) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ALG1L2 Gene

ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ALG1L2 Gene

No ASD Table

Relevant External Links for ALG1L2 Gene

GeneLoc Exon Structure for
ALG1L2
ECgene alternative splicing isoforms for
ALG1L2

Expression for ALG1L2 Gene

mRNA expression in normal human tissues for ALG1L2 Gene

SOURCE GeneReport for Unigene cluster for ALG1L2 Gene Hs.722197

genes like me logo Genes that share expressions with ALG1L2: view

Orthologs for ALG1L2 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for ALG1L2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC739193 36
  • 98.44 (n)
  • 96.26 (a)
Species with no ortholog for ALG1L2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ALG1L2 Gene

ENSEMBL:
Gene Tree for ALG1L2 (if available)
TreeFam:
Gene Tree for ALG1L2 (if available)

Paralogs for ALG1L2 Gene

Selected SIMAP similar genes for ALG1L2 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ALG1L2: view

No data available for Paralogs for ALG1L2 Gene

Variants for ALG1L2 Gene

Sequence variations from dbSNP and Humsavar for ALG1L2 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs2449401 -- 130,096,706(+) AGTTG(A/C)GCCCT intron-variant
rs2587972 -- 130,096,192(-) CTATC(A/C)CCAGA intron-variant
rs2587979 -- 130,081,250(+) CTCAG(A/G)TGATC upstream-variant-2KB
rs2587980 -- 130,081,357(+) ATGGC(C/T)GAGAG upstream-variant-2KB
rs2588003 -- 130,086,984(-) GAAGG(C/T)TCTGG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ALG1L2 Gene

Variant ID Type Subtype PubMed ID
dgv1495e1 CNV Complex 17122850
nsv508954 CNV Insertion 20534489
nsv508242 CNV Loss 20534489
nsv877484 CNV Gain 21882294
dgv1496e1 CNV Complex 17122850
essv5961 CNV CNV 17122850
dgv1497e1 CNV Complex 17122850
dgv1499e1 CNV Complex 17122850
dgv1500e1 CNV Complex 17122850
dgv5256n71 CNV Gain 21882294
nsv4001 CNV Loss 18451855
dgv1501e1 CNV Complex 17122850
esv2725909 CNV Deletion 23290073
dgv5257n71 CNV Gain 21882294
nsv877490 CNV Gain+Loss 21882294
nsv829723 CNV Gain 17160897
nsv820609 CNV Deletion 20802225
esv24757 CNV Gain+Loss 19812545
dgv885e199 CNV Deletion 23128226
esv3466 CNV Deletion 18987735
esv2725910 CNV Deletion 23290073
esv5945 CNV Loss 19470904
nsv499012 CNV Loss 21111241
esv2422077 CNV Deletion 20811451
esv993528 CNV Gain 20482838
nsv442875 CNV CNV 18776908
dgv1503e1 CNV Complex 17122850
dgv1504e1 CNV Complex 17122850
nsv428420 CNV Gain 18775914
nsv822252 CNV Gain 20364138
dgv1506e1 CNV Complex 17122850
essv10508 CNV CNV 17122850
nsv433361 CNV Gain 18776910
nsv877492 CNV Gain 21882294
nsv437340 CNV Loss 16327808
dgv1507e1 CNV Complex 17122850
esv2455918 CNV Loss 19546169

Relevant External Links for ALG1L2 Gene

HapMap Linkage Disequilibrium report
ALG1L2

Disorders for ALG1L2 Gene

No disorders were found for ALG1L2 Gene.

No data available for UniProtKB/Swiss-Prot for ALG1L2 Gene

Publications for ALG1L2 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3
  3. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny D.M. … Gibbs R.A. (Nature 2006) 4

Products for ALG1L2 Gene

Sources for ALG1L2 Gene

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