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Aliases for ALG1L Gene

Aliases for ALG1L Gene

  • ALG1, Chitobiosyldiphosphodolichol Beta-Mannosyltransferase-Like 2 3
  • Asparagine-Linked Glycosylation 1-Like 1 2 3
  • Asparagine-Linked Glycosylation 1-Like 2
  • Putative Glycosyltransferase ALG1-Like 3
  • Beta-1,4-Mannosyltransferase-Like 3
  • EC 2.4.1.- 4
  • ALG1L1 3

External Ids for ALG1L Gene

Previous GeneCards Identifiers for ALG1L Gene

  • GC03M127131
  • GC03M125648
  • GC03M123028

Summaries for ALG1L Gene

GeneCards Summary for ALG1L Gene

ALG1L (ALG1, Chitobiosyldiphosphodolichol Beta-Mannosyltransferase-Like) is a Protein Coding gene. GO annotations related to this gene include transferase activity, transferring glycosyl groups. An important paralog of this gene is ALG1.

UniProtKB/Swiss-Prot for ALG1L Gene

  • Putative glycosyltransferase.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ALG1L Gene

Genomics for ALG1L Gene

Regulatory Elements for ALG1L Gene

Genomic Location for ALG1L Gene

Start:
125,928,840 bp from pter
End:
125,937,044 bp from pter
Size:
8,205 bases
Orientation:
Minus strand

Genomic View for ALG1L Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ALG1L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ALG1L Gene

Proteins for ALG1L Gene

  • Protein details for ALG1L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6GMV1-ALG1L_HUMAN
    Recommended name:
    Putative glycosyltransferase ALG1-like
    Protein Accession:
    Q6GMV1
    Secondary Accessions:
    • D3DNA5

    Protein attributes for ALG1L Gene

    Size:
    187 amino acids
    Molecular mass:
    21132 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ALG1L Gene

Proteomics data for ALG1L Gene at MOPED

Post-translational modifications for ALG1L Gene

No Post-translational modifications

Other Protein References for ALG1L Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ALG1L Gene

Domains for ALG1L Gene

Gene Families for ALG1L Gene

HGNC:
  • GLT1 :Glycosyltransferase group 1 domain containing

Protein Domains for ALG1L Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ALG1L Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6GMV1

UniProtKB/Swiss-Prot:

ALG1L_HUMAN :
  • Q6GMV1
Family:
  • Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 33 subfamily.
genes like me logo Genes that share domains with ALG1L: view

Function for ALG1L Gene

Molecular function for ALG1L Gene

UniProtKB/Swiss-Prot Function:
Putative glycosyltransferase.

Enzyme Numbers (IUBMB) for ALG1L Gene

Gene Ontology (GO) - Molecular Function for ALG1L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000030 mannosyltransferase activity IBA --
GO:0016757 transferase activity, transferring glycosyl groups --
genes like me logo Genes that share ontologies with ALG1L: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ALG1L

In Situ Assay Products

Flow Cytometry Products

No data available for Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ALG1L Gene

Localization for ALG1L Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ALG1L Gene COMPARTMENTS Subcellular localization image for ALG1L gene
Compartment Confidence
cytosol 2
extracellular 2
nucleus 2
plasma membrane 2
cytoskeleton 1

Gene Ontology (GO) - Cellular Components for ALG1L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005783 endoplasmic reticulum IBA --
genes like me logo Genes that share ontologies with ALG1L: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for ALG1L Gene

Pathways for ALG1L Gene

SuperPathways for ALG1L Gene

No Data Available

Interacting Proteins for ALG1L Gene

Gene Ontology (GO) - Biological Process for ALG1L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006486 protein glycosylation IBA --
GO:0008152 metabolic process --
GO:0097502 mannosylation IBA --
genes like me logo Genes that share ontologies with ALG1L: view

No data available for Pathways by source for ALG1L Gene

Transcripts for ALG1L Gene

mRNA/cDNA for ALG1L Gene

(3) REFSEQ mRNAs :
(21) Selected AceView cDNA sequences:
(1) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ALG1L Gene

ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ALG1L

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ALG1L Gene

No ASD Table

Relevant External Links for ALG1L Gene

GeneLoc Exon Structure for
ALG1L
ECgene alternative splicing isoforms for
ALG1L

Expression for ALG1L Gene

mRNA expression in normal human tissues for ALG1L Gene

mRNA differential expression in normal tissues according to GTEx for ALG1L Gene

This gene is overexpressed in Bladder (6.1).

SOURCE GeneReport for Unigene cluster for ALG1L Gene Hs.591299

genes like me logo Genes that share expressions with ALG1L: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for ALG1L Gene

Orthologs for ALG1L Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ALG1L Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ALG1L 35
  • 97.58 (n)
  • 95.65 (a)
ALG1L 36
  • 96 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ALG1 36
  • 27 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 28 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 25 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Alg1 36
  • 26 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 36
  • 23 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 23 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii alg1 36
  • 21 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG18012 36
  • 18 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea T26A5.4 36
  • 13 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes ALG1 36
  • 13 (a)
OneToMany
Species with no ortholog for ALG1L:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ALG1L Gene

ENSEMBL:
Gene Tree for ALG1L (if available)
TreeFam:
Gene Tree for ALG1L (if available)

Paralogs for ALG1L Gene

Paralogs for ALG1L Gene

Selected SIMAP similar genes for ALG1L Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ALG1L: view

Variants for ALG1L Gene

Sequence variations from dbSNP and Humsavar for ALG1L Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs5028611 -- 125,935,287(+) AAATT(G/T)TAGAC intron-variant, upstream-variant-2KB
rs6438946 -- 125,930,974(+) CTCAG(C/T)ACATA intron-variant
rs6438947 -- 125,931,033(+) CTCAG(C/T)TCACA intron-variant
rs6438948 -- 125,931,202(+) CGTTT(A/T)ACTGA intron-variant
rs6438949 -- 125,931,221(+) CACCA(C/G)GTGAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ALG1L Gene

Variant ID Type Subtype PubMed ID
dgv5238n71 CNV Gain 21882294
dgv1491e1 CNV Complex 17122850
nsv877410 CNV Loss 21882294
nsv829716 CNV Gain+Loss 17160897

Relevant External Links for ALG1L Gene

HapMap Linkage Disequilibrium report
ALG1L

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ALG1L Gene

Disorders for ALG1L Gene

Relevant External Links for ALG1L

Genetic Association Database (GAD)
ALG1L

No disorders were found for ALG1L Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for ALG1L Gene

Publications for ALG1L Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. Global identification of modular cullin-RING ligase substrates. (PMID: 21963094) Emanuele M.J. … Elledge S.J. (Cell 2011) 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  4. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny D.M. … Gibbs R.A. (Nature 2006) 4

Products for ALG1L Gene

Sources for ALG1L Gene

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