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Aliases for ALG1L Gene

Aliases for ALG1L Gene

  • ALG1, Chitobiosyldiphosphodolichol Beta-Mannosyltransferase-Like 2 3 5
  • Asparagine-Linked Glycosylation 1-Like 1 2 3
  • Asparagine-Linked Glycosylation 1-Like 2
  • Beta-1,4-Mannosyltransferase-Like 3
  • EC 2.4.1.- 4
  • ALG1L1 3

External Ids for ALG1L Gene

Previous GeneCards Identifiers for ALG1L Gene

  • GC03M127131
  • GC03M125648
  • GC03M123028

Summaries for ALG1L Gene

GeneCards Summary for ALG1L Gene

ALG1L (ALG1, Chitobiosyldiphosphodolichol Beta-Mannosyltransferase-Like) is a Protein Coding gene. GO annotations related to this gene include transferase activity, transferring glycosyl groups and mannosyltransferase activity. An important paralog of this gene is ALG1.

UniProtKB/Swiss-Prot for ALG1L Gene

  • Putative glycosyltransferase.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ALG1L Gene

Genomics for ALG1L Gene

Regulatory Elements for ALG1L Gene

Enhancers for ALG1L Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ALG1L on UCSC Golden Path with GeneCards custom track

Genomic Location for ALG1L Gene

125,928,840 bp from pter
125,952,098 bp from pter
23,259 bases
Minus strand

Genomic View for ALG1L Gene

Genes around ALG1L on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ALG1L Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ALG1L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ALG1L Gene

Proteins for ALG1L Gene

  • Protein details for ALG1L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative glycosyltransferase ALG1-like
    Protein Accession:
    Secondary Accessions:
    • D3DNA5

    Protein attributes for ALG1L Gene

    187 amino acids
    Molecular mass:
    21132 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ALG1L Gene

Proteomics data for ALG1L Gene at MOPED

Post-translational modifications for ALG1L Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ALG1L Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ALG1L Gene

Domains & Families for ALG1L Gene

Gene Families for ALG1L Gene

Protein Domains for ALG1L Gene


Suggested Antigen Peptide Sequences for ALG1L Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 33 subfamily.
  • Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 33 subfamily.
genes like me logo Genes that share domains with ALG1L: view

Function for ALG1L Gene

Molecular function for ALG1L Gene

UniProtKB/Swiss-Prot Function:
Putative glycosyltransferase.

Enzyme Numbers (IUBMB) for ALG1L Gene

Phenotypes for ALG1L Gene

genes like me logo Genes that share phenotypes with ALG1L: view

Animal Model Products

CRISPR Products

No data available for Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ALG1L Gene

Localization for ALG1L Gene

Subcellular locations from

Jensen Localization Image for ALG1L Gene COMPARTMENTS Subcellular localization image for ALG1L gene
Compartment Confidence
endoplasmic reticulum 3
cytosol 2
extracellular 2
nucleus 2
plasma membrane 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ALG1L Gene

Pathways & Interactions for ALG1L Gene

SuperPathways for ALG1L Gene

No Data Available

Interacting Proteins for ALG1L Gene

Gene Ontology (GO) - Biological Process for ALG1L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008152 metabolic process IEA --
genes like me logo Genes that share ontologies with ALG1L: view

No data available for Pathways by source and SIGNOR curated interactions for ALG1L Gene

Drugs & Compounds for ALG1L Gene

No Compound Related Data Available

Transcripts for ALG1L Gene

mRNA/cDNA for ALG1L Gene

(3) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(21) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ALG1L Gene

ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ALG1L Gene

No ASD Table

Relevant External Links for ALG1L Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ALG1L Gene

mRNA expression in normal human tissues for ALG1L Gene

mRNA differential expression in normal tissues according to GTEx for ALG1L Gene

This gene is overexpressed in Bladder (x6.1).

SOURCE GeneReport for Unigene cluster for ALG1L Gene Hs.591299

genes like me logo Genes that share expression patterns with ALG1L: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ALG1L Gene

Orthologs for ALG1L Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ALG1L Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ALG1L 35
  • 97.58 (n)
  • 95.65 (a)
ALG1L 36
  • 96 (a)
(Bos Taurus)
Mammalia ALG1 36
  • 27 (a)
(Canis familiaris)
Mammalia -- 36
  • 28 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 25 (a)
(Mus musculus)
Mammalia Alg1 36
  • 26 (a)
(Gallus gallus)
Aves -- 36
  • 23 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 23 (a)
(Danio rerio)
Actinopterygii alg1 36
  • 21 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG18012 36
  • 18 (a)
(Caenorhabditis elegans)
Secernentea T26A5.4 36
  • 13 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes ALG1 36
  • 13 (a)
Species with no ortholog for ALG1L:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ALG1L Gene

Gene Tree for ALG1L (if available)
Gene Tree for ALG1L (if available)

Paralogs for ALG1L Gene

Paralogs for ALG1L Gene

(2) SIMAP similar genes for ALG1L Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ALG1L: view

Variants for ALG1L Gene

Sequence variations from dbSNP and Humsavar for ALG1L Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
VAR_039962 -
VAR_039963 -
VAR_039964 -
rs1847249 -- 125,950,963(+) GGGCA(G/T)ATAAA intron-variant
rs1847250 -- 125,951,296(+) CCCTC(A/C/G)GTTTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ALG1L Gene

Variant ID Type Subtype PubMed ID
dgv5238n71 CNV Gain 21882294
dgv1491e1 CNV Complex 17122850
nsv877410 CNV Loss 21882294
nsv829716 CNV Gain+Loss 17160897

Variation tolerance for ALG1L Gene

Residual Variation Intolerance Score: 91.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 10.11; 90.24% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ALG1L Gene

Disorders for ALG1L Gene

Relevant External Links for ALG1L

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ALG1L Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ALG1L Gene

Publications for ALG1L Gene

  1. Gene-smoking interactions identify several novel blood pressure loci in the Framingham Heart Study. (PMID: 25189868) Sung Y.J. … Rao D.C. (Am. J. Hypertens. 2015) 3 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ALG1L Gene

Sources for ALG1L Gene