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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ALG13 Gene

protein-coding   GIFtS: 54
GCID: GC0XP110909

ALG13, UDP-N-acetylglucosaminyltransferase subunit

(Previous names: glycosyltransferase 28 domain containing 1, chromosome...)
(Previous symbols: GLT28D1, CXorf45)
 Explore 4 diseases affiliated with
ALG13 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for ALG13    

Aliases
for ALG13 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
ALG13, UDP-N-Acetylglucosaminyltransferase Subunit1 2     Asparagine-Linked Glycosylation 13 Homolog (S. Cerevisiae)1
CXorf451 2 3     Chromosome X Open Reading Frame 451
GLT28D11 2 5     Glycosyltransferase 28 Domain Containing 11
MDS0311 2     CDG1S2
TDRD131 2     Hematopoietic Stem/Progenitor Cells Protein MDS0312
YGL047W1 2     N-Acetylglucosaminyldiphosphodolichol N-Acetylglucosaminyltransferase2
Asparagine-Linked Glycosylation 13 Homolog2 3     Tudor Domain Containing 132
Glycosyltransferase 28 Domain-Containing Protein 12 3     UDP-N-Acetylglucosamine Transferase Subunit ALG13 Homolog2
FLJ230181     EC 2.4.1.1413

External Ids:    HGNC: 308811   Entrez Gene: 798682   Ensembl: ENSG000001019017   OMIM: 3007765   UniProtKB: Q9NP733   
ORGUL members:         
NONCODE:n409066 n409064    

Export aliases for ALG13 gene to outside databases

Previous GC identifers: GC0XP110811 GC0XP100545


Summaries
for ALG13 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for ALG13:
The protein encoded by this gene is a subunit of a bipartite UDP-N-acetylglucosamine transferase. It heterodimerizes
with asparagine-linked glycosylation 14 homolog to form a functional UDP-GlcNAc glycosyltransferase that catalyzes the
second sugar addition of the highly conserved oligosaccharide precursor in endoplasmic reticulum N-linked
glycosylation. Multiple transcript variants encoding different isoforms have been found for this gene. (provided by
RefSeq, Dec 2009)

UniProtKB/Swiss-Prot: ALG13_HUMAN, Q9NP73
Function: Isoform 2 may be involved in protein N-glycosylation, second step of the dolichol-linked oligosaccharide
pathway

Gene Wiki entry for ALG13


Genomic Views
for ALG13 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NC_018934.1  NT_011651.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ALG13 gene promoter:
         Pbx1a   GCNF   NF-E2 p45   TFIID   GCNF-1   COMP1   Cart-1   NF-E2   GCNF-2   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ALG13 promoter sequence
   Search SABiosciences Chromatin IP Primers for ALG13

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ALG13


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq23   Ensembl cytogenetic band:  Xq23   HGNC cytogenetic band: Xq23

ALG13 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ALG13 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP110909:  view genomic region     (about GC identifiers)

Start:
 110,909,043 bp from pter      End:
 111,003,877 bp from pter
Size:
 94,835 bases      Orientation:
 plus strand

Proteins
for ALG13 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: ALG13_HUMAN, Q9NP73 (See protein sequence)
Recommended Name: UDP-N-acetylglucosamine transferase subunit ALG13 homolog  
Size: 1137 amino acids; 126056 Da
Subunit: Isoform 2 may interact with ALG14 (By similarity)
Subcellular location: Isoform 2: Endoplasmic reticulum (Probable). Note=Could be recruited to the cytosolic face of the
endoplasmic reticulum membrane through its interaction with ALG14
Sequence caution: Sequence=AAI17378.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=AAI17380.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAB15521.1;
Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAD96874.1; Type=Erroneous initiation;
Note=Translation N-terminally extended; Sequence=BAH14244.1; Type=Erroneous initiation; Note=Translation N-terminally
extended; Sequence=BAH14244.1; Type=Erroneous termination; Positions=424; Note=Translated as Cys; Sequence=CAI43016.2;
Type=Erroneous gene model prediction; Sequence=CAM28219.1; Type=Erroneous gene model prediction;
Secondary accessions: B1AKD6 B1AKM1 B2R5L5 B7Z6J0 B7Z804 B7Z847 B7Z9A8 B7ZAJ1 B7ZB57 Q17RC3 Q5JXY9
Q9H5U8
Alternative splicing: 4 isoforms:  Q9NP73-1   Q9NP73-2   Q9NP73-3   Q9NP73-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ALG13: NX_Q9NP73

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9NP73

    • ALG13 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (12 alternative transcripts): 
    NP_001034299.3  NP_001093392.1  NP_001161857.1  NP_001244159.1  NP_001244160.1  NP_001244163.1  NP_001244164.1  NP_001244166.1  
    NP_001244168.1  NP_001244169.1  NP_001244170.1  NP_060936.1  

    ENSEMBL proteins: 
     ENSP00000361047   ENSP00000426892   ENSP00000378260   ENSP00000427093   ENSP00000392990  
     ENSP00000251943  
    Reactome Protein details: Q9NP73
    Human Recombinant Protein Products: 
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    OriGene Protein Over-expression Lysate: ALG13
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    Novus Biologicals ALG13 Protein
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for ALG13

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005789endoplasmic reticulum membrane TAS--


    ALG13 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for ALG13

    Protein Domains /
    Families
    for ALG13 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    ALG13 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR003323 OTU
     IPR007235 Glyco_trans_28_C
     IPR002999 Tudor

    Graphical View of Domain Structure for InterPro Entry Q9NP73

    ProtoNet protein and cluster: Q9NP73

    UniProtKB/Swiss-Prot: ALG13_HUMAN, Q9NP73
    Similarity: Belongs to the glycosyltransferase 28 family
    Similarity: Contains 1 OTU domain
    Similarity: Contains 1 Tudor domain


    Function
    for ALG13 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: ALG13_HUMAN, Q9NP73
    Function: Isoform 2 may be involved in protein N-glycosylation, second step of the dolichol-linked oligosaccharide
    pathway
    Catalytic activity: UDP-N-acetyl-D-glucosamine + N-acetyl-D-glucosaminyl-diphosphodolichol = UDP +
    N,N'-diacetylchitobiosyl-diphosphodolichol

    Enzyme Number (IUBMB): EC 2.4.1.1411

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ALG13
    8/36 QIAGEN miScript miRNA Assays for microRNAs that regulate ALG13 (see all 36):
    hsa-miR-548k hsa-miR-218-1* hsa-let-7a-2* hsa-miR-301a hsa-miR-449a hsa-miR-374a* hsa-miR-376a* hsa-miR-130b
    SwitchGear 3'UTR luciferase reporter plasmid: ALG13 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ALG13 (see all 7)
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ALG13

    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004577N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity IEA--
    GO:0016758transferase activity, transferring hexosyl groups ----
    GO:0030246carbohydrate binding IEA--


    ALG13 for ontologies           About GeneDecksing


    Animal Models:
         3 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Alg13):
     cardiovascular system  embryogenesis  mortality/aging 

    ALG13 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for ALG13 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Asparagine N-linked glycosylation
    		Asparagine N-linked glycosylation1.00
    		Post-translational protein modification0.44
    		N-Glycan biosynthesis0.52
    		Metabolism of proteins0.15
    2Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
    		Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein1.00
    		dolichyl-diphosphooligosaccharide biosynthesis0.33
    3Metabolism
    		Metabolic pathways0.38

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 BioSystems Pathway for ALG13 
        dolichyl-diphosphooligosaccharide biosynthesis

    4        Reactome Pathways for ALG13
        Asparagine N-linked glycosylation
    Metabolism of proteins
    Post-translational protein modification
    Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein


    2         Kegg Pathways  (Kegg details for ALG13):
        N-Glycan biosynthesis
    Metabolic pathways


    ALG13 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ALG13

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    5/11 Interacting proteins for ALG13 (Q9NP732, 3 ENSP000003610474) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    REREQ9P2R62, 3, ENSP000003386294MINT-2876453 I2D: score=2 STRING: ENSP00000338629
    ATN1P542592, 3, ENSP000003490764MINT-2876415 I2D: score=2 STRING: ENSP00000349076
    MSNP260383I2D: score=4 
    CUX1P398803I2D: score=1 
    PUF60Q9UHX13I2D: score=1 
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006488dolichol-linked oligosaccharide biosynthetic process TAS--
    GO:0018279protein N-linked glycosylation via asparagine TAS--
    GO:0030259lipid glycosylation IEA--
    GO:0043687post-translational protein modification TAS--
    GO:0044267cellular protein metabolic process TAS--


    ALG13 for ontologies           About GeneDecksing



    Drugs & Compounds
    for ALG13 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ALG13

    4 HMDB Compounds for ALG13    About this table
    CompoundSynonyms CAS #PubMed Ids
    N,N'-DiacetylchitobiosyldiphosphodolicholChitobiosyldiphosphodolichol (see all 2)----
    N-Acetyl-D-glucosaminyldiphosphodolicholN-Acetyl-D-glucosaminyl-diphosphodolichol ----
    Uridine 5'-diphosphate5'-UDP (see all 9)58-98-0--
    Uridine diphosphate-N-acetylglucosamineN-[2-[[[5-[(2,4-dioxo-1H-pyrimidin-1-yl)]-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphinoyl]oxy-hydroxy-phosphinoyl]oxy-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-3-yl]acetamide (see all 30)528-04-1--
    Search CenterWatch for drugs/clinical trials and news about ALG13 

    Transcripts
    for ALG13 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for ALG13 gene (12 alternative transcripts): 
    NM_001039210.3  NM_001099922.2  NM_001168385.1  NM_001257230.1  NM_001257231.1  NM_001257234.1  NM_001257235.1  NM_001257237.1  
    NM_001257239.1  NM_001257240.1  NM_001257241.1  NM_018466.4  

    Unigene Cluster for ALG13:

    Asparagine-linked glycosylation 13 homolog (S. cerevisiae)
    Hs.443061  [show with all ESTs]
    Unigene Representative Sequence: NM_001257231
    18/23 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 23):
    ENST00000487141 ENST00000371979(uc022ccl.1 uc022ccm.1 uc022ccn.1 uc004epi.2 uc022cco.1 uc022ccp.1 uc022ccq.1)
    ENST00000473389 ENST00000482374 ENST00000486353 ENST00000492038 ENST00000394780(uc011msy.2 uc011msz.2)
    ENST00000489033 ENST00000495283 ENST00000471924 ENST00000468657 ENST00000482742
    ENST00000470704 ENST00000436609 ENST00000490774 ENST00000470971 ENST00000460092
    ENST00000486578

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    8/36 QIAGEN miScript miRNA Assays for microRNAs that regulate ALG13 (see all 36):
    hsa-miR-548k hsa-miR-218-1* hsa-let-7a-2* hsa-miR-301a hsa-miR-449a hsa-miR-374a* hsa-miR-376a* hsa-miR-130b
    SwitchGear 3'UTR luciferase reporter plasmid: ALG13 3' UTR sequence
    Inhib. RNA
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    Additional cDNA sequence: 

    AF220051.1 AK026671.1 AK056347.1 AK223154.1 AK300394.1 AK302729.1 AK302890.1 AK304712.1 
    AK311608.1 AK312229.1 AK316306.1 AK316522.1 BC005336.1 BC117377.1 BC117379.1 NR_033125.1 

    24/27 DOTS entries (see all 27):

    DT.113134  DT.448810  DT.91757707  DT.91743885  DT.75101403  DT.91935306  DT.100022949  DT.86847583 
    DT.87006558  DT.97841620  DT.91743884  DT.100788710  DT.121306345  DT.121306350  DT.121306352  DT.91753670 
    DT.91757709  DT.92023993  DT.95271494  DT.121306371  DT.40308966  DT.91653774  DT.91803643  DT.95365627 

    24/209 AceView cDNA sequences (see all 209):

    BQ004828 BF055996 BC005336 BE856439 AA676867 AK056347 AI097292 AL706526 
    AI700032 Z39365 AI277542 CB268871 AA806568 AI281239 AA907248 BM508194 
    CD368075 BP359179 AI373597 BX118776 BQ004489 AA946674 NM_018466 AW290958 

    GeneLoc Exon Structure


    Expression
    for ALG13 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ALG13 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See ALG13 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ALG13

    SOURCE GeneReport for Unigene cluster: Hs.443061
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    In Situ
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    Orthologs
    for ALG13 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for ALG13 gene from 4/14 species (see all 14)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves ALG131 asparagine-linked glycosylation 13 homolog (S. cerevisiae) 69.21(n)
    63.63(a)    		   422339  XM_420312.3  XP_420312.3 
    lizard
    (Anolis carolinensis)    		 Reptilia --
    		 --
    		 72(a)
    		 1 ↔ 1
    		 GL343376.1(479057-496466)
    zebrafish
    (Danio rerio)    		 Actinopterygii alg131 asparagine-linked glycosylation 13 homolog (S. cerevisiae) 56.01(n)
    49.56(a)    		   557181  NM_001031838.1  NP_001027008.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG32516
    otu6
    		 ovarian tumor
    		 22(a)
    17(a)
    		 many ↔ many
    many ↔ many
    		 2L(4688965-4690702)
    X(8379041-8383568)


    ENSEMBL Gene Tree for ALG13 (if available)
    TreeFam Gene Tree for ALG13 (if available) 

    Paralogs
    for ALG13 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ALG13 gene
    OTUD42  
    2 SIMAP similar genes for ALG13 using alignment to 3 protein entries:     ALG13_HUMAN (see all proteins):
    OTUD4    HIN1L

    ALG13 for paralogs           About GeneDecksing



    Genomic Variants
    for ALG13 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/757 NCBI SNPs in ALG13 are shown (see all 757)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr X posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1869416821,2
    		--110922373(+) GAGGCA/GGGAGT 6 -- us2k10--------
    rs1510795211,2
    		--110922401(+) AGGGTA/GGGGCT 12 -- us2k10--------
    rs732663131,2
    		--110922471(+) TTTCTC/GTAACT 12 -- us2k10--------
    rs1901899151,2
    		--110922486(+) ACAGGA/GAAAAG 12 -- us2k10--------
    rs1813977801,2
    		--110922690(+) GGGTCA/CGGCAA 12 -- us2k10--------
    rs1864132121,2
    		--110922887(+) GAATGA/GCGTGA 13 -- us2k10--------
    rs1899168361,2
    		--110922920(+) TGAGCC/TGAGAT 13 -- us2k10--------
    rs24958091,2
    		C,F,--110923334(+) AGACGT/CGGCCT 13 -- us2k14Minor allele frequency- C:0.29NA WA CSA 7
    rs1820965031,2
    		--110923530(+) GCTAGA/GAACAC 13 -- us2k10--------
    rs1852913811,2
    		--110923791(+) TGGAAC/TTTCTG 13 -- us2k10--------

    HapMap Linkage Disequilibrium report for ALG13 (110909043 - 111003877 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for ALG13: --
    Human Gene Mutation Database (HGMD): ALG13

    Locus Specific Mutation Databases (LSDB): ALG13

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ALG13
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    Disorders / Diseases
    for ALG13 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    ALG13 for disorders           About GeneDecksing

    OMIM gene information: 300776    OMIM disorders: --

    4 diseases for ALG13:    About MalaCards
    uterine fibroid    leiomyoma    immunodeficiency    malaria

    1 disease from the University of Copenhagen DISEASES database for ALG13:
    Congenital myasthenic syndrome

    Export disorders for ALG13 gene to outside databases

    Publications
    for ALG13 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ALG13 gene, integrated from 9 sources (see all 22):
    (articles sorted by number of sources associating them with ALG13)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
    2. Alg14 recruits Alg13 to the cytoplasmic face of the endoplasmic reticulum to form a novel bipartite UDP-N-acetylglucosamine transferase required for the second step of N-linked glycosylation. (PubMed id 16100110)1, 2 Gao X.-D.... Dean N. (2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    6. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (2012)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    8. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    9. Membrane topology of the Alg14 endoplasmic reticulum UDP-GlcNAc transferase subunit. (PubMed id 17686769)1 Averbeck N....Dean N. (2007)
    10. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)

    External Searches for ALG13 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing ALG13 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 79868 HGNC: 30881 AceView: GLT28D1andCXorf45 Ensembl:ENSG00000101901 euGenes: HUgn79868
    ECgene: ALG13 Kegg: 79868 H-InvDB: ALG13

    Other Databases showing ALG13 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing ALG13 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ALG13 Pharmacogenomics, SNPs, Pathways
    GGDBhttp://riodb.ibase.aist.go.jp/rcmg/ggdb/Homolog?cat=symbol&symbol=GLT28D1

    Intellectual Property
    for ALG13 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for ALG13 gene:
    Search GeneIP for patents involving ALG13

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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