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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ALG11 Gene

protein-coding   GIFtS: 49
GCID: GC13P052587

ALG11, alpha-1,2-mannosyltransferase

(Previous names: asparagine-linked glycosylation 11 homolog (S. cerevisiae,...)
 Explore 2 diseases affiliated with
ALG11 via our new
 Human Malady Compendium 
Biological research products
for ALG11
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
ALG11, Alpha-1,2-Mannosyltransferase1 2     Asparagine-Linked Glycosylation 11, Alpha-1,2-Mannosyltransferase Homolog
(Yeast)1
Asparagine-Linked Glycosylation Protein 11 Homolog2 3     Asparagine-Linked Glycosylation 11, Alpha-1,2-Mannosyltransferase Homolog2
Glycolipid 2-Alpha-Mannosyltransferase2 3     GDP-Man:Man(3)GlcNAc(2)-PP-Dol Alpha-1,2-Mannosyltransferase2
GT82 3     GDP-Man:Man(3)GlcNAc(2)-PP-Dolichol Alpha-1,2-Mannosyltransferase2
CDG1P2 5     EC 2.4.1.1313
KIAA02661     KIAA12665
Asparagine-Linked Glycosylation 11 Homolog (S. Cerevisiae,
Alpha-1,2-Mannosyltransferase)1
     EC 2.4.18

External Ids:    HGNC: 324561   Entrez Gene: 4401382   Ensembl: ENSG000002537107   OMIM: 6136665   UniProtKB: Q2TAA53   

Export aliases for ALG11 gene to outside databases

Previous GC identifers: GC13P051485 GC13P033375


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ALG11:
This gene encodes a GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase which is localized to the cytosolic
side of the endoplasmic reticulum (ER) and catalyzes the transfer of the fourth and fifth mannose residue from
GDP-mannose (GDP-Man) to Man3GlcNAc2-PP-dolichol and Man4GlcNAc2-PP-dolichol resulting in the production of
Man5GlcNAc2-PP-dolichol. Mutations in this gene are associated with congenital disorder of glycosylation type Ip
(CDGIP). This gene overlaps but is distinct from the UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
gene. A pseudogene of the GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase has been identified on
chromosome 19. (provided by RefSeq, Aug 2010)

UniProtKB/Swiss-Prot: ALG11_HUMAN, Q2TAA5
Function: Mannosyltransferase involved in the last steps of the synthesis of Man5GlcNAc(2)-PP-dolichol core
oligosaccharide on the cytoplasmic face of the endoplasmic reticulum. Catalyzes the addition of the 4th and 5th
mannose residues to the dolichol-linked oligosaccharide chain

Gene Wiki entry for ALG11


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000013.10  NC_018924.1  NT_024524.14  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ALG11 gene promoter:
         HOXA3   Sp1   STAT3   FOXO1a   STAT5A   FOXO1   C/EBPalpha   GATA-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidALG11 promoter sequence
   Search SABiosciences Chromatin IP Primers for ALG11

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ALG11


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q14.2   Ensembl cytogenetic band:  13q14.3   HGNC cytogenetic band: 13q14.3

ALG11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ALG11 gene location

GeneLoc information about chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13P052587:  view genomic region     (about GC identifiers)

Start:
52,586,534 bp from pter      End:
52,603,800 bp from pter
Size:
17,267 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ALG11_HUMAN, Q2TAA5 (See protein sequence)
Recommended Name: GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase  
Size: 492 amino acids; 55651 Da
Subcellular location: Endoplasmic reticulum. Endoplasmic reticulum membrane; Multi-pass membrane protein (Probable)
Sequence caution: Sequence=AAI11023.1; Type=Frameshift; Positions=16;
Secondary accessions: A5PLP3 B4DKW9 Q5TAN9 Q6DKI6 Q96FI7

Explore the universe of human proteins at neXtProt for ALG11: NX_Q2TAA5

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q2TAA5

  • 3 DME Specific Peptides for ALG11 (Q2TAA5)
     MWNEHFGI  CNAGGGGE  GGGGERVLW 

    ALG11 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_001004127.2  
    ENSEMBL proteins: 
     ENSP00000429497   ENSP00000430236  
    Reactome Protein details: Q2TAA5
    Human Recombinant Protein Products: 
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    Uscn Proteins for ALG11

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005789endoplasmic reticulum membrane IEA--
    GO:0016021integral to membrane IEA--
    GO:0030529ribonucleoprotein complex ----


    ALG11 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ALG11 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR001296 Glyco_trans_1

    Graphical View of Domain Structure for InterPro Entry Q2TAA5

    ProtoNet protein and cluster: Q2TAA5

    2 Blocks protein families:
    IPB000595 Cyclic nucleotide-binding domain
    IPB001296 Glycosyl transferase


    UniProtKB/Swiss-Prot: ALG11_HUMAN, Q2TAA5
    Similarity: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: ALG11_HUMAN, Q2TAA5
    Function: Mannosyltransferase involved in the last steps of the synthesis of Man5GlcNAc(2)-PP-dolichol core
    oligosaccharide on the cytoplasmic face of the endoplasmic reticulum. Catalyzes the addition of the 4th and 5th
    mannose residues to the dolichol-linked oligosaccharide chain
    Catalytic activity: 2 GDP-alpha-D-mannose +
    D-Man-alpha-(1->3)-(D-Man-alpha-(1->6))-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol = 2 GDP +
    D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-(D-Man-alpha-(1->6))-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol

    Enzyme Numbers (IUBMB): EC 2.4.12 EC 2.4.1.1311

    miRNA
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate ALG11:
    hsa-miR-3163
    SwitchGear 3'UTR luciferase reporter plasmidALG11 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ALG11

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0004377GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity IEA--


    ALG11 for ontologies           About GeneDecksing



    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Asparagine N-linked glycosylation
    Asparagine N-linked glycosylation1.00
    Post-translational protein modification0.44
    N-Glycan biosynthesis0.52
    Metabolism of proteins0.15
    2Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
    Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein1.00
    3Metabolism
    Metabolic pathways0.38

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    4        Reactome Pathways for ALG11
        Asparagine N-linked glycosylation
    Metabolism of proteins
    Post-translational protein modification
    Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein


    2         Kegg Pathways  (Kegg details for ALG11):
        N-Glycan biosynthesis
    Metabolic pathways


    ALG11 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ALG11

    5/14 Interacting proteins for ALG11 (Q2TAA53) via UniProtKB, MINT, STRING, and/or I2D (see all 14)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ALG1Q9BT223I2D: score=2 
    ALG2Q9H5533I2D: score=1 
    ALG3Q926853I2D: score=1 
    ATP13A1Q9HD203I2D: score=1 
    CYB5R2Q6BCY43I2D: score=1 
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006488dolichol-linked oligosaccharide biosynthetic process TAS--
    GO:0018279protein N-linked glycosylation via asparagine TAS--
    GO:0043687post-translational protein modification TAS--
    GO:0044267cellular protein metabolic process TAS--


    ALG11 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ALG11
    Search CenterWatch for drugs/clinical trials and news about ALG11 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ALG11 gene: 
    NM_001004127.2  

    Unigene Cluster for ALG11:

    Asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog (yeast)
    Hs.512963  [show with all ESTs]
    Unigene Representative Sequence: D87455
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000523764(uc001vfz.2) ENST00000521508 ENST00000519151

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    1 QIAGEN miScript miRNA Assays for microRNA that regulate ALG11:
    hsa-miR-3163
    SwitchGear 3'UTR luciferase reporter plasmidALG11 3' UTR sequence
    Inhib. RNA
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ALG11 
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    Additional cDNA sequence: 

    AK025456.1 AK296747.1 BC010857.2 BC073862.1 BC089407.1 BC108677.1 BC111022.1 BC122536.1 
    BC142998.1 D87455.1 NR_036571.2 

    8 DOTS entries:

    DT.86996757  DT.97789163  DT.105713  DT.453307  DT.100689584  DT.120790404  DT.100786425  DT.120790352 

    24/187 AceView cDNA sequences (see all 187):

    Z40767 AW271597 BM023472 BC010857 AU132282 BC073862 CR602797 BM479135 
    BX473993 AA442866 BX369206 BM993493 AA781749 AL708143 AK025456 AA709377 
    AA954436 AI206392 AI338808 AL705052 BM931845 F05368 AA781748 AA812710 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ALG11 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ATTTATATCT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See ALG11 Protein Expression from SPIRE MOPED and PaxDB
    SOURCE GeneReport for Unigene cluster: Hs.512963
        SABiosciences Custom PCR Arrays for ALG11
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ALG11 gene from 9/31 species (see all 31)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Alg111 , 5 asparagine-linked glycosylation 11 homolog (yeast, more5
    asparagine-linked glycosylation 11 (alpha-1,2-mannosyltransferase)1
    85.99(n)1
    86.53(a)1
      8 (10.92 cM)5
    2079581  NM_001243161.11  NP_001230090.11 
     220607215 
    chicken
    (Gallus gallus)
    Aves ALG111 asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase more 73.07(n)
    73.35(a)
      418880  NM_001199825.1  NP_001186754.1 
    lizard
    (Anolis carolinensis)
    Reptilia ALG116
    --
    71(a)
    1 ↔ 1
    1(132792077-132795838)
    zebrafish
    (Danio rerio)
    Actinopterygii alg111 asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase 63.13(n)
    65.49(a)
      407614  NM_001161351.1  NP_001154823.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG113061 CG11306 53.99(n)
    50.85(a)
      40402  NM_141083.3  NP_649340.1 
    worm
    (Caenorhabditis elegans)
    Secernentea B0361.81 Protein B0361.8 52.18(n)
    46.96(a)
      176032  NM_066205.3  NP_498606.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes ALG111 Alg11p 53.04(n)
    41.99(a)
      855679   NP_014350.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons LEW31 alpha-1,2-mannosyltransferase 53.03(n)
    47.28(a)
      818610  NM_129577.4  NP_181548.2 
    rice
    (Oryza sativa)
    Liliopsida Os12g05830001 hypothetical protein 52.5(n)
    46.35(a)
      4352649  NM_001073676.1  NP_001067144.2 


    ENSEMBL Gene Tree for ALG11 (if available)
    TreeFam Gene Tree for ALG11 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ALG11 gene

    ALG11 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for ALG11
    PGOHUM00000234480


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/119 NCBI SNPs in ALG11 are shown (see all 119    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 13 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs73276341,2
    C,F,A,H,--52587745(+) AAGGAA/CTTGCC 2 -- int121Minor allele frequency- C:0.34NA NS EA CSA WA 2470
    rs73280901,2
    C,F,A,--52587806(+) AAAGAT/GTGTCC 2 -- int111Minor allele frequency- G:0.13NA WA CSA 254
    rs1503465051,2
    --52587868(+) CAAATA/GTTAAA 2 -- int10--------
    rs1807769081,2
    --52587950(+) CATGGA/GCCATG 2 -- int10--------
    rs1380594961,2
    --52588032(+) ATTTTA/CCTATG 2 -- int10--------
    rs1860737271,2
    --52588039(+) TATGTC/TGATAA 2 -- int10--------
    rs24085441,2
    C,F,A,H,--52588096(+) TAACAG/CTGTGA 2 -- int111Minor allele frequency- C:0.39NS EA NA CSA WA 782
    rs1913667321,2
    --52588098(+) ACAGTA/GTGAAA 2 -- int10--------
    rs1428503801,2
    --52588243(+) CAATAC/TATATT 2 -- int10--------
    rs1826877751,2
    --52588375(+) TTTCAC/TGTTAA 2 -- int10--------

    HapMap Linkage Disequilibrium report for ALG11 (52586534 - 52603800 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for ALG11: --
    Human Gene Mutation Database (HGMD): ALG11

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    ALG11 for disorders           About GeneDecksing

    OMIM gene information: 613666   
    OMIM disorders: 613661  
    UniProtKB/Swiss-Prot: ALG11_HUMAN, Q2TAA5
  • Defects in ALG11 are the cause of congenital disorder of glycosylation type 1P (CDG1P) [MIM:613661]. A
  • multisystem disorder caused by a defect in glycoprotein biosynthesis and characterized by under-glycosylated serum
    glycoproteins. Congenital disorders of glycosylation result in a wide variety of clinical features, such as defects in
    the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and
    immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic
    development, differentiation, and maintenance of cell functions

    2 diseases for ALG11:    About MalaCards
    congenital disorder of glycosylation    hypotonia

    1 disease from the University of Copenhagen DISEASES database for ALG11:
    Congenital disorder of glycosylation
    Human Genome Epidemiology (HuGE) Navigator: ALG11 (1 document)

    Export disorders for ALG11 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ALG11 gene, integrated from 9 sources (see all 11):
    (articles sorted by number of sources associating them with ALG11)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A severe human metabolic disease caused by deficiency of the endoplasmatic mannosyltransferase hALG11 leads to congenital disorder o f glycosylation-Ip. (PubMed id 20080937)1, 2, 3 Rind N....KAPrner C. (2010)
    2. Improved diagnostics lead to identification of three new patients with congenital disorder of glycosylation-Ip. (PubMed id 22213132)1, 2 Thiel C.... Korner C. (2012)
    3. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    4. Large-scale mapping of human protein-protein interactions by mass spectrometry. (PubMed id 17353931)1 Ewing R.M.... Figeys D. (2007)
    5. UTP14c is a recently acquired retrogene associated with spermatogenesis and fertility in man. (PubMed id 16354793)1 Rohozinski J....Bishop C.E. (2006)
    6. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)1 Suzuki Y.... Sugano S. (2004)
    7. The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)2 Dunham A.... Ross M.T. (2004)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    9. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 440138 HGNC: 32456 AceView: UTP14C Ensembl:ENSG00000253710 euGenes: HUgn440138
    ECgene: ALG11 Kegg: 440138 H-InvDB: ALG11

    (According to HUGE)
    About This Section
    HUGE: KIAA0266 KIAA1266

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ALG11 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ALG11 gene:
    Search GeneIP for patents involving ALG11

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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