ALG1 Gene
protein-coding GIFtS: 61
GCID: GC16P005121
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ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase(Previous names: asparagine-linked glycosylation 1 homolog (yeast, beta-1,4-mannosyltransferase),...)
| |
Aliases
for ALG1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| ALG1, Chitobiosyldiphosphodolichol Beta-Mannosyltransferase1 2 | | CDG1K2 5 | | HMAT11 2 3 5 | | Asparagine-Linked Glycosylation 1, Beta-1,4-Mannosyltransferase Homolog (S.Cerevisiae)1 | | HMT12 3 5 | | Mat-12 | | HMT-11 2 | | Asparagine-Linked Glycosylation 1, Beta-1,4-Mannosyltransferase Homolog2 | | Asparagine-Linked Glycosylation 1 Homolog (Yeast, Beta-1,4-Mannosyltransferase)1 2 | | Beta-1,4 Mannosyltransferase2 | | Asparagine-Linked Glycosylation Protein 1 Homolog2 3 | | Beta-1,4-Mannosyltransferase1 | | MT-12 3 | | Chitobiosyldiphosphodolichol Beta-Mannosyltransferase2 | | GDP-Man:GlcNAc2-PP-Dolichol Mannosyltransferase2 3 | | Mannosyltransferase-13 | | GDP-Mannose-Dolichol Diphosphochitobiose Mannosyltransferase2 3 | | Beta-1,4-Mannosyltransferase1 | | HMat-11 | | Mannosyltransferase-13 | | EC 2.4.1.1423 8 | | |
Export aliases for ALG1 gene to outside databasesPrevious GC identifers: GC16P005122 GC16P005061 |
Summaries
for ALG1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ALG1:
The enzyme encoded by this gene catalyzes the first mannosylation step in the biosynthesis of lipid-linkedoligosaccharides. This gene is mutated in congenital disorder of glycosylation type Ik. (provided by RefSeq, Dec 2008)
UniProtKB/Swiss-Prot: ALG1_HUMAN, Q9BT22Function: Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved inassembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER
Gene Wiki entry for ALG1
|
Genomic Views
for ALG1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010393.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ALG1 gene promoter:
STAT5B STAT4 STAT6 STAT1beta STAT5A XBP-1 STAT1alpha Zic1 STAT2 STAT3
Other transcription factors
Search SABiosciences Chromatin IP Primers for ALG1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ALG1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16p13.3 Ensembl cytogenetic band: 16p13.3 HGNC cytogenetic band: 16p13.3ALG1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16P005121: view genomic region
(about GC identifiers)
Start:
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5,083,703 bp from pter |
End:
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5,137,380 bp from pter |
Size:
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53,678 bases |
Orientation:
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plus strand |
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Proteins
for ALG1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ALG1_HUMAN, Q9BT22 (See
protein sequence)Recommended Name: Chitobiosyldiphosphodolichol beta-mannosyltransferase Size: 464 amino acids; 52518 Da
Subcellular location: Endoplasmic reticulum membrane; Single-pass type II membrane protein (Probable)
Sequence caution: Sequence=AAQ89432.1; Type=Erroneous initiation;
Secondary accessions: Q6UVZ9 Q8N5Y4 Q9P2Y2Explore the universe of human proteins at neXtProt for ALG1: NX_Q9BT22
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9BT22
2 DME Specific Peptides for ALG1 (Q9BT22)
ALG1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_061982.3
ENSEMBL proteins: ENSP00000468118 ENSP00000262374 ENSP00000467538 ENSP00000467865 ENSP00000464700 ENSP00000440019 Reactome Protein details: Q9BT22
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
ALG1 for ontologies About GeneDecksing
ALG1 Antibody Products:
Assay Products for ALG1: |
Protein
Domains /
Families
for ALG1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ALG1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9BT22ProtoNet protein and cluster: Q9BT22 1 Blocks protein family: IPB001296 Glycosyl transferase
UniProtKB/Swiss-Prot: ALG1_HUMAN, Q9BT22Similarity: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 33 subfamily |
Function
for ALG1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ALG1_HUMAN, Q9BT22Function: Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved inassembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ERCatalytic activity: GDP-mannose + chitobiosyldiphosphodolichol = GDP + beta-1,4-D-mannosylchitobiosyldiphosphodolicholEnzyme Number (IUBMB): EC 2.4.1.1421 2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ALG1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ALG1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ALG1 (NM_019109) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ALG1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ALG1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ALG1 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000030 | mannosyltransferase activity |
TAS | 10704531 | | GO:0004578 | chitobiosyldiphosphodolichol beta-mannosyltransferase activity |
IEA | -- | | GO:0016757 | transferase activity, transferring glycosyl groups |
-- | -- |
ALG1 for ontologies About GeneDecksing
|
Pathways & Interactions
for ALG1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Asparagine N-linked glycosylation | | | 2 | Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | | | 3 | Metabolism | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for ALG1
4 
Reactome Pathways for ALG1
2 
Kegg Pathways (Kegg details for ALG1):
UniProtKB/Swiss-Prot: ALG1_HUMAN, Q9BT22Pathway: Protein modification; protein glycosylation
ALG1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ALG1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 16)
5/43 Interacting proteins for ALG1 (Q9BT223 ENSP000002623744) via UniProtKB, MINT, STRING, and/or I2D (see all 43)
About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006486 | protein glycosylation |
TAS | 10704531 | | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process |
TAS | -- | | GO:0009103 | lipopolysaccharide biosynthetic process |
TAS | 10704531 | | GO:0018279 | protein N-linked glycosylation via asparagine |
TAS | -- | | GO:0043687 | post-translational protein modification |
TAS | -- |
ALG1 for ontologies About GeneDecksing
|
Drugs & Compounds
for ALG1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
ALG1 for compounds About GeneDecksing
 Browse Tocris compounds for ALG1
4 HMDB Compounds for ALG1 About this table
4 Novoseek chemical compound relationships for ALG1 gene About this table
Search CenterWatch for drugs/clinical trials and news about ALG1
|
Transcripts
for ALG1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ALG1 gene: NM_019109.4 Unigene Cluster for ALG1: Asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog (S. cerevisiae) Hs.592086 [show with all ESTs]Unigene Representative Sequence: NM_0191099 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000591961 ENST00000588623 ENST00000262374(uc002cyj.3 uc002cym.3 uc010bue.3)
ENST00000586840 ENST00000592793 ENST00000591822 ENST00000591783 ENST00000544428
ENST00000592661
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ALG1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ALG1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ALG1 (NM_019109) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ALG1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ALG1 |
Additional cDNA sequence: AB019038.1 AK075373.1 AK298144.1 AK311475.1 AY359073.1 BC004402.1 BC031095.1 14 DOTS entries: DT.101959683 DT.450414 DT.120724762 DT.100753178 DT.120724737 DT.95148344 DT.100825780 DT.120724733 DT.97809662 DT.120724740 DT.120724771 DT.120724777 DT.95320948 DT.100649176 24/242 AceView cDNA sequences (see all 242): AI273221 BU186622 AA680361 BQ935553 CR619322 AI371094 CA391104 BM856363 AI802901 CR624559 CB993327 BF438369 BX376384 AA700910 BM852978 BQ688867 BM791409 BM559894 AA380399 AY359073 CR597195 BM801720 CD110151 BM728596
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for ALG1 (see all 6) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11 |
|---|
|
| SP1: | | | - | | - | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP4: | | | - | | - | | - | | | | | | | | - | | - | | | | | | | | | | | | | | | | |
| SP5: | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ALG1
|
Expression
for ALG1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ALG1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See ALG1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ALG1
SOURCE GeneReport for Unigene cluster: Hs.592086
SABiosciences Custom PCR Arrays for ALG1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ALG1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ALG1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ALG1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ALG1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ALG1 |
Orthologs
for ALG1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for ALG1 gene from 9/31 species (see all 31) About this table
ENSEMBL Gene Tree for ALG1 (if available)
TreeFam Gene Tree for ALG1 (if available) |
Paralogs
for ALG1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ALG1 gene
- ALG1L2
3 SIMAP similar genes for ALG1 using alignment to 5 protein entries: ALG1_HUMAN (see all proteins):OR7E86P ALG1L2 ALG1L
ALG1 for paralogs About GeneDecksing
5 Pseudogenes.org Pseudogenes for ALG1
PGOHUM00000250382 PGOHUM00000237751 PGOHUM00000237831 PGOHUM00000249999 PGOHUM00000250021
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Genomic Variants
for ALG1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ALG1 (5083703 - 5137380 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 8 variations for ALG1
8 CNVs: 87946 72445 9755 8811 5436 3989 3101 72444
Human Gene Mutation Database (HGMD): ALG1
Locus Specific Mutation Databases (LSDB): ALG1
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ALG1 |
|
Disorders
/ Diseases
for ALG1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ALG1 for disorders About GeneDecksing
OMIM gene information: 605907
OMIM disorders: 608540
UniProtKB/Swiss-Prot: ALG1_HUMAN, Q9BT22
Defects in ALG1 are the cause of congenital disorder of glycosylation type 1K (CDG1K) [MIM:608540]. CDGs are afamily of severe inherited diseases caused by a defect in protein N-glycosylation. They are characterized byunder-glycosylated serum proteins. These multisystem disorders present with a wide variety of clinical features, suchas disorders of the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulationdisorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins duringembryonic development, differentiation, and maintenance of cell functions
12  diseases for ALG1: About MalaCardscongenital disorder of glycosylation congenital disorder of glycosylation type 1k walker-warburg syndrome hydrops fetalis
fukuyama congenital muscular dystrophy congenital muscular dystrophy muscular dystrophy hypotonia
thyroid carcinoma thyroiditis carcinoma neuronitis
2 diseases from the University of Copenhagen DISEASES database for ALG1:Walker-Warburg syndrome Congenital disorder of glycosylation GeneTests: ALG1
Congenital Disorders of Glycosylation
Human Genome Epidemiology (HuGE) Navigator: ALG1 (1 document)
Export disorders for ALG1 gene to outside databases
|
Publications
for ALG1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ALG1 gene, integrated from 9 sources (see all 33):
(articles sorted by number of sources associating them with ALG1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning of the human cDNA which can complement the defect of the yeast mannosyltransferase I-deficient mutant alg 1. (PubMed id 10704531)1, 2, 3, 9 Takahashi T.... Nishikawa Y. (2000)
- Deficiency of the first mannosylation step in the N-glycosylation pathway causes congenital disorder of glycosylation type Ik. (PubMed id 14709599)1, 2, 9 Grubenmann C.E.... Hennet T. (2004)
- Congenital disorder of glycosylation type Ik (CDG-Ik): a defect of mannosyltransferase I. (PubMed id 14973782)1, 2, 9 Kranz C.... Marquardt T. (2004)
- Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (2005)
- Deficiency of GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase causes congenital disorder of glycosylation type Ik. (PubMed id 14973778)1, 2 Schwarz M.... Koerner C. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
- Defining the phenotype in congenital disorder of glyco sylation due to ALG1 mutations. (PubMed id 22966035)1 Morava E....Wevers R.A. (2012)
- Genome-wide association study identifies novel loci as sociated with circulating phospho- and sphingolipid concentrations. (PubMed id 22359512)1 Demirkan A....Schmitz G. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
|
External Searches for ALG1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ALG1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ALG1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ALG1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ALG1 | Pharmacogenomics, SNPs, Pathways | | GGDB | http://riodb.ibase.aist.go.jp/rcmg/ggdb/ | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/ALG1 |
|
| | |
About This Section
| Patent Information for ALG1 gene:
Search GeneIP for patents involving ALG1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ALG1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ALG1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ALG1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ALG1 | | | OriGene Protein Over-expression Lysate for ALG1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ALG1 | | OriGene 3'-UTR Clone for ALG1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ALG1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ALG1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for ALG1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ALG1 | | OriGene Custom Protein Services for ALG1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ALG1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ALG1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ALG1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ALG1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ALG1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ALG1 |
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| | | | Search Tocris compounds for ALG1 |
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 | | | ALG1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ALG1 |
|  |  |  | | | | ThermoFisher Antibodies for ALG1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ALG1 |
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