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ALDH3B2 Gene

protein-coding   GIFtS: 60
GCID: GC11M067429

Aldehyde Dehydrogenase 3 Family, Member B2


(Previous symbol: ALDH8)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Aldehyde Dehydrogenase 3 Family, Member B21 2     EC 1.2.1.53 8
ALDH81 2 3 5     Aldehyde Dehydrogenase Family 3 Member B22
Aldehyde Dehydrogenase 81 2 3     EC 1.2.18
Acetaldehyde Dehydrogenase 81 2     

External Ids:    HGNC: 4111   Entrez Gene: 2222   Ensembl: ENSG000001327467   OMIM: 6019175   UniProtKB: P484483   

Export aliases for ALDH3B2 gene to outside databases

Previous GC identifers: GC11M069952 GC11M069125 GC11M067679 GC11M067204 GC11M067186 GC11M063759


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ALDH3B2 Gene:
This gene encodes a member of the aldehyde dehydrogenase family, a group of isozymes that may play a major role in
the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The gene of this
particular family member is over 10 kb in length. The expression of these transcripts is restricted to the
salivary gland among the human tissues examined. Alternate transcriptional splice variants have been
characterized. (provided by RefSeq, Jul 2008)

GeneCards Summary for ALDH3B2 Gene:
ALDH3B2 (aldehyde dehydrogenase 3 family, member B2) is a protein-coding gene. GO annotations related to this gene include 3-chloroallyl aldehyde dehydrogenase activity and aldehyde dehydrogenase [NAD(P)+] activity. An important paralog of this gene is ALDH3A1.

Gene Wiki entry for ALDH3B2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NC_018922.2  NT_167190.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ALDH3B2 gene promoter:
         USF1   Pax-5   MyoD   Lmo2   LCR-F1   C/EBPalpha   E47   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): ALDH3B2 promoter sequence
   Search Chromatin IP Primers for ALDH3B2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ALDH3B2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q13   Ensembl cytogenetic band:  11q13.2   HGNC cytogenetic band: 11q13

ALDH3B2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ALDH3B2 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M067429:  view genomic region     (about GC identifiers)

Start:
67,429,633 bp from pter      End:
67,448,685 bp from pter
Size:
19,053 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: AL3B2_HUMAN, P48448 (See protein sequence)
Recommended Name: Aldehyde dehydrogenase family 3 member B2  
Size: 385 amino acids; 42635 Da
Secondary accessions: Q53Y98 Q8NAL5 Q96IB2

Explore the universe of human proteins at neXtProt for ALDH3B2: NX_P48448

Explore proteomics data for ALDH3B2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for ALDH3B2 (P48448) (see all 9)
     EKPLALY  TLELGGK  VTLELGG  NAGQTCV 


    See ALDH3B2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_000686.2  NP_001026786.1  

    ENSEMBL proteins: 
     ENSP00000431595   ENSP00000435476   ENSP00000433718   ENSP00000433466   ENSP00000255084  

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    Cloud-Clone Corp. Proteins for ALDH3B2

     
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    antibodies-online proteins for ALDH3B2 (3 products) 

     
    antibodies-online peptides for ALDH3B2

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ALDH: Aldehyde dehydrogenases

    Selected InterPro protein domains (see all 6):
     IPR016163 Ald_DH_C
     IPR016162 Ald_DH_N
     IPR012394 Aldehyde_DH_NAD(P)
     IPR016161 Ald_DH/histidinol_DH
     IPR015590 Aldehyde_DH_dom

    Graphical View of Domain Structure for InterPro Entry P48448

    ProtoNet protein and cluster: P48448

    1 Blocks protein domain: IPB002086 Aldehyde dehydrogenase

    UniProtKB/Swiss-Prot: AL3B2_HUMAN, P48448
    Similarity: Belongs to the aldehyde dehydrogenase family


    Find genes that share domains with ALDH3B2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: AL3B2_HUMAN, P48448
    Catalytic activity: An aldehyde + NAD(P)(+) + H(2)O = a carboxylate + NAD(P)H

         Enzyme Numbers (IUBMB): EC 1.2.1.51 2 EC 1.2.12

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:00040283-chloroallyl aldehyde dehydrogenase activity TAS8890755
    GO:0004030aldehyde dehydrogenase [NAD(P)+] activity IEA--
    GO:0016491oxidoreductase activity ----
         
    Find genes that share ontologies with ALDH3B2           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for ALDH3B2:
     Increased Salmonella enterica   Increased cell number in G2M,  

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for ALDH3B2

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    hsa-mir-7-5p (MIRT025818), hsa-mir-124-3p (MIRT022852), hsa-mir-148b-3p (MIRT019455)

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    chloroplast2
    extracellular2
    plasma membrane2
    endoplasmic reticulum1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ALDH3B2 About   (see all 7)  
    See pathways by source

    SuperPathContained pathways About
    1Chemical carcinogenesis
    Chemical carcinogenesis0.71
    Drug metabolism - cytochrome P4500.69
    Metabolism of xenobiotics by cytochrome P4500.71
    2Phenylalanine metabolism
    Phenylalanine metabolism0.36
    Tyrosine metabolism0.36
    3Glycolysis and gluconeogenesis short map
    Glycolysis / Gluconeogenesis0.46
    4Metabolism
    Metabolic pathways0.38
    5putrescine degradation III
    putrescine degradation III


    Find genes that share SuperPaths with ALDH3B2           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 BioSystems Pathway for ALDH3B2
        putrescine degradation III



    Selected Kegg Pathways  (Kegg details for ALDH3B2) (see all 9):
        Glycolysis / Gluconeogenesis
    Histidine metabolism
    Tyrosine metabolism
    Phenylalanine metabolism
    beta-Alanine metabolism

    UniProtKB/Swiss-Prot: AL3B2_HUMAN, P48448
    Pathway: Alcohol metabolism; ethanol degradation; acetate from ethanol: step 2/2

        Pathway & Disease-focused RT2 Profiler PCR Array including ALDH3B2: 

              Drug Metabolism: Phase I Enzymes in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for ALDH3B2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for ALDH3B2 (P484483 ENSP000002550844) via UniProtKB, MINT, STRING, and/or I2D (see all 47)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CLN3Q132863I2D: score=1 
    ABATENSP000002682514STRING: ENSP00000268251
    ACSS1ENSP000003169244STRING: ENSP00000316924
    ACSS2ENSP000003538044STRING: ENSP00000353804
    ADH1AENSP000002096684STRING: ENSP00000209668
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006066alcohol metabolic process TAS8890755
    GO:0006068ethanol catabolic process IEA--
    GO:0006081cellular aldehyde metabolic process ----
    GO:0006629lipid metabolic process TAS8890755
    GO:0008152metabolic process ----

    Find genes that share ontologies with ALDH3B2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ALDH3B2 (AL3B2)

    Selected HMDB Compounds for ALDH3B2 (see all 20)    About this table
    CompoundSynonyms CAS #PubMed Ids
    3,4-Dihydroxybenzeneacetic acid(3,4-Dihydroxyphenyl)acetate (see all 23)102-32-9--
    3,4-Dihydroxymandelaldehyde3,4-Dihydroxyphenylglycolaldehyde (see all 4)13023-73-9--
    3,4-DihydroxyphenylacetaldehydeProtocatechuatealdehyde (see all 2)5707-55-1--
    3-Methoxy-4-hydroxyphenylglycolaldehydea,4-dihydroxy-3-methoxy-Benzeneacetaldehyde (see all 4)17592-23-3--
    Acetaldehydeacetaldehyde (see all 5)75-07-0--
    Acetic acidAcetate (see all 12)64-19-7--
    Ethanol1-Hydroxyethane (see all 57)64-17-5--
    Homovanillic acid(4-Hydroxy-3-methoxyphenyl)acetate (see all 14)306-08-1--
    Homovanillin(4-Hydroxy-3-methoxyphenyl)acetaldehyde (see all 5)5703-24-2--
    Methylimidazole acetaldehyde1-Methylimidazole-4-acetaldehyde (see all 2)19639-03-3--

    1 DrugBank Compound for ALDH3B2    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    NADHbeta-DPNH (see all 18)606-68-8target--17139284 17016423



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ALDH3B2 gene (2 alternative transcripts): 
    NM_000695.3  NM_001031615.1  

    Unigene Cluster for ALDH3B2:

    Aldehyde dehydrogenase 3 family, member B2
    Hs.87539  [show with all ESTs]
    Unigene Representative Sequence: AK092464
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000530069(uc001oms.3) ENST00000531248 ENST00000534425 ENST00000525827
    ENST00000528756 ENST00000531881 ENST00000533962 ENST00000349015(uc001omr.3 uc009ysa.1)

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    Additional mRNA sequence: 

    AK092464.1 AK299956.1 AK309277.1 BC007685.2 BT006810.1 U56857.1 

    14 DOTS entries:

    DT.100814383  DT.95163433  DT.314959  DT.100031447  DT.120750955  DT.120750959  DT.120751002  DT.92019028 
    DT.120750963  DT.120750998  DT.40117840  DT.40190021  DT.99930882  DT.40190024 

    Selected AceView cDNA sequences (see all 114):

    W72907 BM983115 AI905356 BG696473 CA487680 AL702999 BG696112 BF125919 
    BE407478 AU136629 BE410638 BG697888 BF436411 AA513758 CD109470 AU133823 
    BE410093 BT006810 CA488805 BE410820 AA579992 AW170354 BX476313 BC007685 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for ALDH3B2    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13
    SP1:              -     -     -     -                                                               
    SP2:                                                                                                
    SP3:                                -                                                               
    SP4:                    -     -     -                                                               
    SP5:                                                                                                


    ECgene alternative splicing isoforms for ALDH3B2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ALDH3B2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GACTTCTGTC
    ALDH3B2 Expression
    About this image

    ALDH3B2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ALDH3B2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.87539

    UniProtKB/Swiss-Prot: AL3B2_HUMAN, P48448
    Tissue specificity: Salivary gland

        Pathway & Disease-focused RT2 Profiler PCR Array including ALDH3B2: 
              Drug Metabolism: Phase I Enzymes in human mouse rat

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ALDH3B2 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Aldh3b25 aldehyde dehydrogenase 3 family, member B2   --   19 (3.69 cM) 3972328 
    chicken
    (Gallus gallus)
    Aves --
    --
    Aldehyde dehydrogenase
    48(a)
    48(a)
    many ↔ many
    many ↔ many
    5(188165-199244) ENSGALG00000028936
    5(181927-188067) ENSGALG00000003490
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Aldehyde dehydrogenase
    46(a)
    46(a)
    many ↔ many
    many ↔ many
    1(93474583-93478804)
    1(93468360-93510336)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia AL845910.22   -- 70.03(n)    AL845910.2 
    zebrafish
    (Danio rerio)
    Actinopterygii AF254955.12   -- 71.43(n)   282559  AF254955.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Aldh-III3 aldehyde dehydrogenase 53(a)   43C5   --
    worm
    (Caenorhabditis elegans)
    Secernentea alh-56
    alh-46
    Protein ALH-4, isoform a
    35(a)
    34(a)
    many ↔ many
    many ↔ many
    V(1996109-1999581) WBGene00000111
    V(6427211-6429927) WBGene00000110
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes HFD16
    Putative fatty aldehyde dehydrogenase, located in ...
    25(a)
    1 → many
    XIII(490394-491992) YMR110C
    corn
    (Zea mays)
    Liliopsida Zm.172942 Zea mays CL5928_2 mRNA sequence 77.6(n)    AY104932.1 


    ENSEMBL Gene Tree for ALDH3B2 (if available)
    TreeFam Gene Tree for ALDH3B2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ALDH3B2 gene
    ALDH3A12  ALDH3B12  ALDH3A22  
    5 SIMAP similar genes for ALDH3B2 using alignment to 4 protein entries:     AL3B2_HUMAN (see all proteins):
    ALDH3B1    ALDH3A2    ALDH3A1    DKFZp686E23276    ALDH5A1

    Find genes that share paralogs with ALDH3B2           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for ALDH3B2
    PGOHUM00000250407


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ALDH3B2 (see all 746)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs118269301,2
    H--67348991(+) aaaaaA/Ttaaaa 2 -- ds50010--------
    rs118247471,2
    H--67348992(+) aaaaaA/Taaaaa 2 -- ds50010--------
    rs1432508361,2
    --67349094(+) TACCAC/TTTTTA 2 -- ds50010--------
    rs618945241,2
    C,F--67349173(+) CTTGAC/GCCCAG 2 -- ds50017Minor allele frequency- G:0.13WA NA CSA EA 366
    rs800938911,2
    C,F--67349175(+) TGACCC/GCAGGA 2 -- ds50011Minor allele frequency- G:0.03NA 120
    rs1821001631,2
    --67349303(+) AACAGA/GTGAAT 2 -- ut310--------
    rs1431295101,2
    --67349454(+) TCACAA/GGCTGA 2 -- ut310--------
    rs1164437161,2
    C,F--67349473(+) GTTGGC/TGATGG 2 -- ut311Minor allele frequency- T:0.03WA 118
    rs1474735491,2
    C--67349490(+) GGTGGA/GGACGG 2 -- ut310--------
    rs1888599961,2
    --67349560(+) CCATAC/TGCCCT 2 -- ut310--------

    HapMap Linkage Disequilibrium report for ALDH3B2 (67429633 - 67448685 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for ALDH3B2 (see all 19):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2744646CNV Deletion23290073
    esv1206079CNV Deletion17803354
    dgv161e201CNV Deletion23290073
    esv2744645CNV Deletion23290073
    esv2179266CNV Deletion18987734
    esv2662033CNV Deletion23128226
    esv2744648CNV Deletion23290073
    esv2744649CNV Deletion23290073
    esv2422195CNV Duplication17116639
    esv27185CNV Loss19812545

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ALDH3B2
    DNA2.0 Custom Variant and Variant Library Synthesis for ALDH3B2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 601917    OMIM disorders: --


    Find genes that share disorders with ALDH3B2           About GenesLikeMe

    Genetic Association Database (GAD): ALDH3B2
    Human Genome Epidemiology (HuGE) Navigator: ALDH3B2 (2 documents)

    Export disorders for ALDH3B2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ALDH3B2 gene, integrated from 10 sources (see all 17):
    (articles sorted by number of sources associating them with ALDH3B2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Sequencing and expression of the human ALDH8 encoding a new member of the aldehyde dehydrogenase family. (PubMed id 8890755)1, 2, 3 Hsu L.C. and Chang W.-C. (Gene 1996)
    2. Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. (PubMed id 19343046)1, 4 Saito A....Kamatani N. (J. Hum. Genet. 2009)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Human aldehyde dehydrogenase genes, ALDH7 and ALDH8: genomic organization and gene structure comparison. (PubMed id 9161417)1, 3 Hsu L.C....Yoshida A. (Gene 1997)
    6. Cloning and characterization of genes encoding four additional human aldehyde dehydrogenase isozymes. (PubMed id 7484374)1, 2 Hsu L.C.... Yoshida A. (Adv. Exp. Med. Biol. 1995)
    7. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    8. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    9. Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (J. Biol. Chem. 2011)
    10. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 222 HGNC: 411 AceView: ALDH3B2 Ensembl:ENSG00000132746 euGenes: HUgn222
    ECgene: ALDH3B2 Kegg: 222 H-InvDB: ALDH3B2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ALDH3B2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ALDH3B2 gene:
    Search GeneIP for patents involving ALDH3B2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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