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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ALDH3B1 Gene

protein-coding   GIFtS: 60
GCID: GC11P067776

aldehyde dehydrogenase 3 family, member B1


(Previous symbol: ALDH7)
 Explore 5 diseases affiliated with
ALDH3B1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for ALDH3B1    

Aliases
for ALDH3B1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Aldehyde Dehydrogenase 3 Family, Member B11 2     ALDH42
ALDH71 2 3 5     Aldehyde Dehydrogenase 3B12
Aldehyde Dehydrogenase 72 3     Aldehyde Dehydrogenase Family 3 Member B12
EC 1.2.1.53 8     EC 1.2.18

External Ids:    HGNC: 4101   Entrez Gene: 2212   Ensembl: ENSG000000065347   OMIM: 6004665   UniProtKB: P433533   

Export aliases for ALDH3B1 gene to outside databases

Previous GC identifers: GC11P070300 GC11P069474 GC11P068027 GC11P067553 GC11P067534 GC11P064111


Summaries
for ALDH3B1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for ALDH3B1:
The aldehyde dehydrogenases are a family of isozymes that may play a major role in the detoxification of aldehydes
generated by alcohol metabolism and lipid peroxidation. This particular gene spans about 20 kb of genomic DNA and is
composed of 9 coding exons. The gene is highly expressed in kidney and lung. The functional significance of this gene
as well as the cellular localization of its product are presently unknown. Alternatively spliced transcript variants
encoding different isoforms have been found for this gene. (provided by RefSeq, Jun 2009)

UniProtKB/Swiss-Prot: AL3B1_HUMAN, P43353
Function: Oxidizes medium and long chain saturated and unsaturated aldehydes. Metabolizes also benzaldehyde. Low
activity towards acetaldehyde and 3,4-dihydroxyphenylacetaldehyde. May not metabolize short chain aldehydes. May use
both NADP(+) and NAD(+) as cofactors. May have a protective role against the cytotoxicity induced by lipid
peroxidation

Gene Wiki entry for ALDH3B1


Genomic Views
for ALDH3B1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.1  NT_167190.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ALDH3B1 gene promoter:
         AML1a   Pax-5   MIF-1   E47   Egr-2   AREB6   POU2F1   POU2F1a   HOXA5   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ALDH3B1 promoter sequence
   Search SABiosciences Chromatin IP Primers for ALDH3B1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ALDH3B1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q13   Ensembl cytogenetic band:  11q13.2   HGNC cytogenetic band: 11q13

ALDH3B1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ALDH3B1 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P067776:  view genomic region     (about GC identifiers)

Start:
 67,776,048 bp from pter      End:
 67,796,744 bp from pter
Size:
 20,697 bases      Orientation:
 plus strand

Proteins
for ALDH3B1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: AL3B1_HUMAN, P43353 (See protein sequence)
Recommended Name: Aldehyde dehydrogenase family 3 member B1  
Size: 468 amino acids; 51840 Da
Secondary accessions: A3FMP9 Q53XL5 Q8N515 Q96CK8
Alternative splicing: 2 isoforms:  P43353-1   P43353-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ALDH3B1: NX_P43353

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P43353

    • 4/9 DME Specific Peptides for ALDH3B1 (P43353) (see all 9)
     EKPLALY  TLELGGK  VTLELGG  NAGQTCV 

    ALDH3B1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (3 alternative transcripts): 
    NP_000685.1  NP_001025181.1  NP_001154945.1  

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    Uscn Proteins for ALDH3B1

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA--


    ALDH3B1 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for ALDH3B1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    ALDH3B1 for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR016162 Ald_DH_N
     IPR012394 Aldehyde_DH_NAD(P)
     IPR016163 Ald_DH_C
     IPR016161 Ald_DH/histidinol_DH
     IPR015590 Aldehyde_DH_dom

    Graphical View of Domain Structure for InterPro Entry P43353

    ProtoNet protein and cluster: P43353

    1 Blocks protein family: IPB002086 Aldehyde dehydrogenase

    UniProtKB/Swiss-Prot: AL3B1_HUMAN, P43353
    Similarity: Belongs to the aldehyde dehydrogenase family


    Function
    for ALDH3B1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: AL3B1_HUMAN, P43353
    Function: Oxidizes medium and long chain saturated and unsaturated aldehydes. Metabolizes also benzaldehyde. Low
    activity towards acetaldehyde and 3,4-dihydroxyphenylacetaldehyde. May not metabolize short chain aldehydes. May use
    both NADP(+) and NAD(+) as cofactors. May have a protective role against the cytotoxicity induced by lipid
    peroxidation
    Catalytic activity: An aldehyde + NAD(P)(+) + H(2)O = a carboxylate + NAD(P)H

    Enzyme Numbers (IUBMB): EC 1.2.1.51 2 EC 1.2.12

    miRNA
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    Gene Editing
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    Clone
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:00040283-chloroallyl aldehyde dehydrogenase activity TAS7828891
    GO:0004030aldehyde dehydrogenase [NAD(P)+] activity IDA--


    ALDH3B1 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for ALDH3B1:
     Upregulation of Wnt/beta-caten 

    Animal Models:
         1 MGI phenotypic allele for Aldh3b1 (no phenotypes)

    ALDH3B1 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for ALDH3B1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/7 super-pathways (see all 7) About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Drug metabolism - cytochrome P450
    		Drug metabolism - cytochrome P4501.00
    		Metabolism of xenobiotics by cytochrome P4500.73
    2Tyrosine metabolism
    		Tyrosine metabolism1.00
    		Phenylalanine metabolism0.35
    3beta-Alanine metabolism
    		beta-Alanine metabolism1.00
    4Histidine metabolism
    		Histidine metabolism1.00
    5Glycolysis and gluconeogenesis (short map)
    		Glycolysis / Gluconeogenesis0.41

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 BioSystems Pathway for ALDH3B1 
        putrescine degradation III


    5/8         Kegg Pathways  (Kegg details for ALDH3B1) (see all 8):
        Glycolysis / Gluconeogenesis
    Histidine metabolism
    Tyrosine metabolism
    Phenylalanine metabolism
    beta-Alanine metabolism

    UniProtKB/Swiss-Prot: AL3B1_HUMAN, P43353
    Pathway: Alcohol metabolism; ethanol degradation; acetate from ethanol: step 2/2


    ALDH3B1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ALDH3B1

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006066alcohol metabolic process TAS7828891
    GO:0006068ethanol catabolic process IEA--
    GO:0006629lipid metabolic process TAS7828891
    GO:0034599cellular response to oxidative stress IDA--
    GO:0046185aldehyde catabolic process IDA--


    ALDH3B1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for ALDH3B1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for ALDH3B1

    10/20 HMDB Compounds for ALDH3B1 (see all 20)    About this table
    CompoundSynonyms CAS #PubMed Ids
    3,4-Dihydroxybenzeneacetic acid(3,4-Dihydroxyphenyl)acetate (see all 23)102-32-9--
    3,4-Dihydroxymandelaldehyde3,4-Dihydroxyphenylglycolaldehyde (see all 4)13023-73-9--
    3,4-DihydroxyphenylacetaldehydeProtocatechuatealdehyde (see all 2)5707-55-1--
    3-Methoxy-4-hydroxyphenylglycolaldehydea,4-dihydroxy-3-methoxy-Benzeneacetaldehyde (see all 4)17592-23-3--
    Acetaldehydeacetaldehyde (see all 5)75-07-0--
    Acetic acidAcetate (see all 12)64-19-7--
    Ethanol1-Hydroxyethane (see all 57)64-17-5--
    Homovanillic acid(4-Hydroxy-3-methoxyphenyl)acetate (see all 14)306-08-1--
    Homovanillin(4-Hydroxy-3-methoxyphenyl)acetaldehyde (see all 5)5703-24-2--
    Methylimidazole acetaldehyde1-Methylimidazole-4-acetaldehyde (see all 2)19639-03-3--

    1 DrugBank Compound for ALDH3B1    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    NADHbeta-DPNH (see all 18)606-68-8target--17139284 17016423

    Search CenterWatch for drugs/clinical trials and news about ALDH3B1 / AL3B1 

    Transcripts
    for ALDH3B1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for ALDH3B1 gene (3 alternative transcripts): 
    NM_000694.2  NM_001030010.1  NM_001161473.1  

    Unigene Cluster for ALDH3B1:

    Aldehyde dehydrogenase 3 family, member B1
    Hs.523841  [show with all ESTs]
    Unigene Representative Sequence: NM_001161473
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000433100 ENST00000529232(uc001omy.1 uc001onb.3) ENST00000531459
    ENST00000434449 ENST00000530046 ENST00000525518 ENST00000527179 ENST00000526609
    ENST00000527514 ENST00000316367 ENST00000539229(uc010rpy.2) ENST00000007633(uc001omz.3)
    ENST00000342456(uc001ona.3)

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    Inhib. RNA
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    Clone
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    Additional cDNA sequence: 

    AK291505.1 BC002553.2 BC013584.2 BC014168.2 BC033099.1 BT009832.1 EF411198.1 U10868.1 
    X75688.1 

    11 DOTS entries:

    DT.86994362  DT.95285234  DT.100778771  DT.100834382  DT.102824711  DT.100031448  DT.101984822  DT.100834381 
    DT.92442872  DT.99969472  DT.95072622 

    24/168 AceView cDNA sequences (see all 168):

    BC033099 BU552605 BM991067 AA601588 BU632191 T51743 BU542769 BU541159 
    BF725348 BQ896809 BQ927085 BQ944633 AA626293 BQ960848 BM990586 AI335963 
    CA313550 BM048417 BI908469 BI193434 BM083543 BU542338 BV189794 AX747322 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for ALDH3B1 (see all 6)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10a · 10b ^ 11 ^ 12 ^ 13a · 13b
    SP1:                                                  -     -     -     -                                 
    SP2:                    -                                                                                 
    SP3:                    -           -                                                                     
    SP4:                                                                                                      
    SP5:        -     -     -                                                                                 


    ECgene alternative splicing isoforms for ALDH3B1

    Expression
    for ALDH3B1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ALDH3B1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CTGCTCATCC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    ALDH3B1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 2 LifeMap Cells 
    NameCategory
    Alveolar type II cells (Derivation of mature...)Lung
    Mature follicles (In-vitro growth and ...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See ALDH3B1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ALDH3B1

    SOURCE GeneReport for Unigene cluster: Hs.523841

    UniProtKB/Swiss-Prot: AL3B1_HUMAN, P43353
    Tissue specificity: Highest expression in kidney and lung

        SABiosciences Expression via Pathway-Focused PCR Arrays including ALDH3B1: 
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              Drug Metabolism: Phase I Enzymes in human mouse rat

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    In Situ
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    Orthologs
    for ALDH3B1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ALDH3B1 gene from 7/15 species (see all 15)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Aldh3b11 , 5 aldehyde dehydrogenase 3 family, member B11, 5 83.4(n)1
    83.76(a)1    		   19 (3.63 cM)5
    676891  NM_026316.21  NP_080592.21 
     39134915 
    chicken
    (Gallus gallus)    		 Aves ALDH3B11 aldehyde dehydrogenase 3 family, member B1 71.56(n)
    64.25(a)    		   428813  XM_426371.3  XP_426371.2 
    zebrafish
    (Danio rerio)    		 Actinopterygii aldh3b11 aldehyde dehydrogenase 3 family, member B1 57.11(n)
    53.88(a)    		   282559  NM_173221.2  NP_775328.2 
    fruit fly
    (Drosophila melanogaster)    		 Insecta Aldh-III1 , 3 aldehyde dehydrogenase3
    Aldehyde dehydrogenase type III1    		 50(a)3
    58.2(n)1
    51.89(a)1    		   43C53
    453981  NM_165531.21  NP_724565.31 
    baker's yeast
    (Saccharomyces cerevisiae)    		 Saccharomycetes HFD11 Hfd1p 42.12(n)
    34.55(a)    		   855137   NP_013828.1 
    Alicante grape
    (Vitis vinifera)    		 eudicotyledons Vvi.75772 Vitis vinifera transcribed sequence with weak similarity more 76.5(n)    CF512188.1 
    rice
    (Oryza sativa)    		 Liliopsida Os.182492 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 72.04(n)    AF464932.1 


    ENSEMBL Gene Tree for ALDH3B1 (if available)
    TreeFam Gene Tree for ALDH3B1 (if available) 

    Paralogs
    for ALDH3B1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    		  --

    Genomic Variants
    for ALDH3B1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/425 NCBI SNPs in ALDH3B1 are shown (see all 425)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 11 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs22861721,2
    		C,F,H,--64109190(-) GGGGAC/TCTCCC 1 -- us2k15Minor allele frequency- T:0.00EA NS 1918
    rs124187741,2
    		C,F,H,--64109287(+) CTGAGA/GGTTGG 1 -- us2k117Minor allele frequency- G:0.06NS EA NA WA 2340
    rs770404721,2
    		F,--64109582(+) CTGGGC/TCCTGG 1 -- us2k11Minor allele frequency- T:0.03WA 118
    rs1910651,2
    		H--64110236(-) acctaG/Tgttag 1 -- us2k14Minor allele frequency- T:0.00NS EA 416
    rs1910641,2
    		H--64110310(-) TCTCAG/TCACCT 1 -- us2k14Minor allele frequency- T:0.00NS EA 420
    rs787900621,2
    		--64110495(+) CCACTC/GCCCCT 1 -- us2k10--------
    rs3083401,2
    		C,--64110561(+) TCCTGG/ATGCCC 1 -- us2k14Minor allele frequency- A:0.12NA WA 124
    rs754236741,2
    		C,F,--64110878(+) CCCTCG/AGGATC 3 -- us2k14Minor allele frequency- A:0.17WA CSA 124
    rs3083371,2
    		C,F,A,H,--64111348(+) AGGCCC/AAGGAA 3 -- us2k1 int111Minor allele frequency- A:0.08NS EA NA WA CSA 806
    rs3083361,2
    		C,F,A,H,--64111376(-) TGTGGA/GGGAAG 3 -- int1 us2k1 trp38Minor allele frequency- G:0.10NS EA NA WA 528

    HapMap Linkage Disequilibrium report for ALDH3B1 (67776048 - 67796744 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 6 variations for ALDH3B1
         6 CNVs: 2931 29914 3856 53160 30558 29913

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    Disorders / Diseases
    for ALDH3B1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    ALDH3B1 for disorders           About GeneDecksing

    OMIM gene information: 600466    OMIM disorders: --

    5 diseases for ALDH3B1:    About MalaCards
    paranoid schizophrenia    alcoholism    hepatitis b    schizophrenia
    hepatitis

    Genetic Association Database (GAD): ALDH3B1
    Human Genome Epidemiology (HuGE) Navigator: ALDH3B1 (4 documents)

    Export disorders for ALDH3B1 gene to outside databases

    Publications
    for ALDH3B1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ALDH3B1 gene, integrated from 9 sources (see all 19):
    (articles sorted by number of sources associating them with ALDH3B1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning of a cDNA encoding human ALDH7, a new member of the aldehyde dehydrogenase family. (PubMed id 7828891)1, 2, 3, 9 Hsu L.C.... Yoshida A. (1994)
    2. Expression and initial characterization of human ALDH3B1. (PubMed id 17382292)1, 2 Marchitti S.A.... Vasiliou V. (2007)
    3. Multi-locus association study of schizophrenia susceptibility genes with a posterior probability method. (PubMed id 16092759)1, 4 Sun X....Li Y. (2005)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. Human aldehyde dehydrogenase genes, ALDH7 and ALDH8: genomic organization and gene structure comparison. (PubMed id 9161417)1, 3 Hsu L.C....Yoshida A. (1997)
    7. Evidence of Epistasis Between the Catechol-O-Methyltransferase and Aldehyde Dehydrogenase 3B1 Genes in Paranoid Schizophrenia. (PubMed id 19159868)1, 9 Wang Y....Shen Y. (2009)
    8. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    9. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    10. Ubiquitin ligase substrate identification through qua ntitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (2011)

    External Searches for ALDH3B1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    Genome Databases showing ALDH3B1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 221 HGNC: 410 AceView: ALDH3B1 Ensembl:ENSG00000006534 euGenes: HUgn221
    ECgene: ALDH3B1 Kegg: 221 H-InvDB: ALDH3B1

    Other Databases showing ALDH3B1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing ALDH3B1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ALDH3B1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for ALDH3B1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for ALDH3B1 gene:
    Search GeneIP for patents involving ALDH3B1

    GeneCards and IP:
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