Aliases for ALDH1L1 Gene
External Ids for ALDH1L1 Gene
Previous Symbols for ALDH1L1 Gene
The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
GeneCards Summary for ALDH1L1 Gene
ALDH1L1 (Aldehyde Dehydrogenase 1 Family, Member L1) is a Protein Coding gene. Diseases associated with ALDH1L1 include methanol poisoning and congenital hydrocephalus. Among its related pathways are One carbon pool by folate and One carbon pool by folate. GO annotations related to this gene include methyltransferase activity and formyltetrahydrofolate dehydrogenase activity. An important paralog of this gene is ALDH1A2.