External Ids for ALB Gene
Previous GeneCards Identifiers for ALB Gene
This gene encodes the most abundant protein in human blood. This protein functions in the regulation of blood plasma colloid osmotic pressure and acts as a carrier protein for a wide range of endogenous molecules including hormones, fatty acids, and metabolites, as well as exogenous drugs. Additionally, this protein exhibits an esterase-like activity with broad substrate specificity. The encoded preproprotein is proteolytically processed to generate the mature protein. A peptide derived from this protein, EPI-X4, is an endogenous inhibitor of the CXCR4 chemokine receptor. [provided by RefSeq, Jul 2016]
GeneCards Summary for ALB Gene
ALB (Albumin) is a Protein Coding gene. Diseases associated with ALB include Analbuminemia and Congenital Analbuminemia. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Defective SLCO1B3 causes hyperbilirubinemia, Rotor type (HBLRR). GO annotations related to this gene include enzyme binding and chaperone binding. An important paralog of this gene is AFP.
UniProtKB/Swiss-Prot for ALB Gene
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.