Aliases for ALB Gene
External Ids for ALB Gene
Previous GeneCards Identifiers for ALB Gene
Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. [provided by RefSeq, Jul 2008]
GeneCards Summary for ALB Gene
ALB (Albumin) is a Protein Coding gene. Diseases associated with ALB include Analbuminemia and Congenital Analbuminemia. Among its related pathways are Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers and Ca, cAMP and Lipid Signaling. GO annotations related to this gene include enzyme binding and chaperone binding. An important paralog of this gene is AFM.
UniProtKB/Swiss-Prot for ALB Gene
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.