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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

AKTIP Gene

protein-coding   GIFtS: 54
GCID: GC16M053524

AKT Interacting Protein

(Previous names: fused toes (mouse) homolog, fused toes homolog (mouse))
(Previous symbol: FTS)
Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
AKT Interacting Protein1 2     Fused Toes Homolog (Mouse)1
FTS1 2 3 5     AKT-Interacting Protein2
Fused Toes Protein Homolog2 3     Fused Toes Homolog2
FT12 5     Ft13
Fused Toes (Mouse) Homolog1     

External Ids:    HGNC: 167101   Entrez Gene: 644002   Ensembl: ENSG000001669717   OMIM: 6084835   UniProtKB: Q9H8T03   

Export aliases for AKTIP gene to outside databases

Previous GC identifers: GC16M052082 GC16M039412


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for AKTIP Gene:
The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while
homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological
abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is
similar to the ubiquitin ligase domain of other ubiquitin-conjugating enzymes but lacks the conserved cysteine
residue that enables those enzymes to conjugate ubiquitin to the target protein. This protein interacts directly
with serine/threonine kinase protein kinase B (PKB)/Akt and modulates PKB activity by enhancing the
phosphorylation of PKB's regulatory sites. Alternative splicing results in two transcript variants encoding the
same protein. (provided by RefSeq, Jul 2008)

GeneCards Summary for AKTIP Gene: 
AKTIP (AKT interacting protein) is a protein-coding gene. Diseases associated with AKTIP include balanitis xerotica obliterans, and thymic hyperplasia. GO annotations related to this gene include protein binding and small conjugating protein ligase activity.

UniProtKB/Swiss-Prot: AKTIP_HUMAN, Q9H8T0
Function: Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle
trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Regulates
apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the
AKT1/GSK3B/NFATC1 signaling cascade

Gene Wiki entry for AKTIP Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NT_010498.15  NC_018927.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the AKTIP gene promoter:
         Oct-B1   LHX3b/Lhx3b   oct-B3   oct-B2   p53   ATF-2   MyoD   AP-4   LHX3a/Lhx3a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidAKTIP promoter sequence
   Search SABiosciences Chromatin IP Primers for AKTIP

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AKTIP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q12.2   Ensembl cytogenetic band:  16q12.2   HGNC cytogenetic band: 16q12.2

AKTIP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AKTIP gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M053524:  view genomic region     (about GC identifiers)

Start:
53,525,192 bp from pter      End:
53,538,323 bp from pter
Size:
13,132 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: AKTIP_HUMAN, Q9H8T0 (See protein sequence)
Recommended Name: AKT-interacting protein  
Size: 292 amino acids; 33128 Da
Subunit: Component of the FTS/Hook/FHIP complex (FHF complex), composed of AKTIP/FTS, FAM160A2, and one or more
members of the Hook family of proteins HOOK1, HOOK2, and HOOK3. May interact directly with HOOK1, HOOK2 and
HOOK3. The FHF complex associates with the homotypic vesicular sorting complex (the HOPS complex). Also interacts
with AKT1
Subcellular location: Cytoplasm. Cell membrane; Peripheral membrane protein
Caution: Lacks the conserved Cys residue necessary for ubiquitin-conjugating enzyme E2 activity
Secondary accessions: Q503B1 Q53H38
Alternative splicing: 2 isoforms:  Q9H8T0-1   Q9H8T0-2   

Explore the universe of human proteins at neXtProt for AKTIP: NX_Q9H8T0

Explore proteomics data for AKTIP at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9H8T0

  • AKTIP Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    AKTIP Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001012398.1  NP_071921.1  

    ENSEMBL proteins: 
     ENSP00000300245   ENSP00000378152   ENSP00000455874   ENSP00000454269   ENSP00000456418  
     ENSP00000458118   ENSP00000454771   ENSP00000456922   ENSP00000456398  

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    Cloud-Clone Corp. Proteins for AKTIP 

    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0005794Golgi apparatus IDA--
    GO:0005886plasma membrane IDA--
    GO:0030897colocalizes with HOPS complex IDA18799622

    AKTIP for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    UBE2: Ubiquitin-conjugating enzymes E2

    2 InterPro protein domains:
     IPR016135 UBQ-conjugating_enzyme/RWD
     IPR000608 UBQ-conjugat_E2

    Graphical View of Domain Structure for InterPro Entry Q9H8T0

    ProtoNet protein and cluster: Q9H8T0

    1 Blocks protein domain: IPB000608 Ubiquitin-conjugating enzymes

    UniProtKB/Swiss-Prot: AKTIP_HUMAN, Q9H8T0
    Similarity: Belongs to the ubiquitin-conjugating enzyme family. FTS subfamily


    AKTIP for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: AKTIP_HUMAN, Q9H8T0
    Function: Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle
    trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Regulates
    apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the
    AKT1/GSK3B/NFATC1 signaling cascade

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI18799622
    GO:0016881acid-amino acid ligase activity ----
    GO:0019787NOT small conjugating protein ligase activity NAS18799622
         
    AKTIP for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for AKTIP:
     Decreased influenza A H1N1 (A/  Decreased influenza A H1N1 (A/  Decreased influenza A/WSN/33 r 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for AKTIP 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for AKTIP 
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    SwitchGear 3'UTR luciferase reporter plasmidAKTIP 3' UTR sequence
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for AKTIP

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/42 Interacting proteins for AKTIP (Q9H8T02, 3 ENSP000003002454) via UniProtKB, MINT, STRING, and/or I2D (see all 42)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GTF3C1Q127892, 3MINT-64321 I2D: score=5 
    IMMTQ168912, 3MINT-64322 I2D: score=5 
    KIAA1377Q9P2H02, 3MINT-64328 I2D: score=5 
    POLA2Q141812, 3MINT-64326 I2D: score=5 
    RPA1P276942, 3MINT-64320 I2D: score=5 
    About this table

    Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001934positive regulation of protein phosphorylation IDA14749367
    GO:0006915apoptotic process IEA--
    GO:0007032endosome organization IMP18799622
    GO:0007040lysosome organization IMP18799622
    GO:0008333endosome to lysosome transport IMP18799622

    AKTIP for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for AKTIP

    Search CenterWatch for drugs/clinical trials and news about AKTIP

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for AKTIP gene (2 alternative transcripts): 
    NM_001012398.1  NM_022476.2  

    Unigene Cluster for AKTIP:

    AKT interacting protein
    Hs.380897  [show with all ESTs]
    Unigene Representative Sequence: AK098222
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000300245 ENST00000394657(uc002ehk.3 uc002ehl.3 uc002ehm.3)
    ENST00000565431 ENST00000570004 ENST00000568022 ENST00000563928 ENST00000563108(uc010vgx.2)
    ENST00000565408 ENST00000568596 ENST00000566045 ENST00000561799 ENST00000570041
    ENST00000564497
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    8/23 QIAGEN miScript miRNA Assays for microRNAs that regulate AKTIP (see all 23):
    hsa-miR-302d hsa-miR-520e hsa-miR-106a hsa-miR-302e hsa-miR-3162-5p hsa-miR-520a-3p hsa-miR-372 hsa-miR-93
    SwitchGear 3'UTR luciferase reporter plasmidAKTIP 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AK023320.1 AK098222.1 AK222743.1 AK303503.1 AL133106.1 BC001134.2 BC095401.1 CR457308.1 

    14 DOTS entries:

    DT.91760647  DT.448175  DT.100653052  DT.100653002  DT.95360281  DT.100653049  DT.100810221  DT.100686955 
    DT.91760640  DT.120660010  DT.95360300  DT.100876483  DT.99958778  DT.120848711 

    24/216 AceView cDNA sequences (see all 216):

    NM_022476 CD721976 BP374980 CK823054 AI572288 D58004 AI804367 AI803999 
    AI367047 BE222226 BQ722242 BF724708 AI276789 F01365 BU507920 AW592536 
    CB156425 AA426333 AA426334 BM992149 AA824387 BE467093 CR457308 BC001134 

    GeneLoc Exon Structure

    5/14 Alternative Splicing Database (ASD) splice patterns (SP) for AKTIP (see all 14)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11a · 11b · 11c ^ 12a · 12b ^ 13 ^ 14a · 14b ^ 15a · 15b ·
    SP1:              -     -     -     -     -                                   -                 -                 -                       -                     
    SP2:              -     -     -     -     -                                   -                 -                 -                       -                     
    SP3:                    -     -     -     -                                   -                 -                 -                       -                     
    SP4:                    -     -     -     -                                   -                 -                 -                                             
    SP5:                                -     -                                   -                 -                 -                                             

    ExUns: 15c · 15d
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for AKTIP

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    AKTIP expression in normal human tissues (normalized intensities)      AKTIP embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TATGCATAGG
    AKTIP Expression
    About this image


    AKTIP expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/2 selected tissues (see all 2) fully expand
     
     Gonad (Reproductive System)
             Primordial Germ Cells Primitive Gonad
     
     Eye (Sensory Organs)
             Glycinergic Amacrine Cells Inner Nuclear Layer

    See AKTIP Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for AKTIP

    SOURCE GeneReport for Unigene cluster: Hs.380897
        SABiosciences Custom PCR Arrays for AKTIP
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AKTIP

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for AKTIP gene from 7/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Aktip1 , 5 thymoma viral proto-oncogene 1 interacting protein1, 5 89.61(n)1
    96.23(a)1
      8 (44.25 cM)5
    143391  NM_010241.41  NP_034371.11 
     911120415 
    chicken
    (Gallus gallus)
    Aves AKTIP1 AKT interacting protein 80.71(n)
    87.67(a)
      415720  NM_001005838.1  NP_001005838.1 
    lizard
    (Anolis carolinensis)
    Reptilia AKTIP6
    Uncharacterized protein
    87(a)
    1 ↔ 1
    LGc(454053-474162)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.339302 Xenopus laevis transcribed sequence with moderate similarity more 77.52(n)    BJ622387.1 
    zebrafish
    (Danio rerio)
    Actinopterygii fts2 fused toes homolog 78.39(n)   378716  BC044455.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta cbx1 crossbronx 50.08(n)
    39.34(a)
      47272  NM_080149.3  NP_524888.1 
    worm
    (Caenorhabditis elegans)
    Secernentea ubc-196
    Protein UBC-19
    26(a)
    1 ↔ 1
    V(18686321-18689843)


    ENSEMBL Gene Tree for AKTIP (if available)
    TreeFam Gene Tree for AKTIP (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for AKTIP gene
    1 SIMAP similar gene for AKTIP using alignment to 7 protein entries:     AKTIP_HUMAN (see all proteins):
    DKFZp434G1122

    AKTIP for paralogs           About GeneDecksing


    4 Pseudogenes.org Pseudogenes for AKTIP
    PGOHUM00000242433 PGOHUM00000247893 PGOHUM00000238041 PGOHUM00000235533


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/272 SNPs in AKTIP are shown (see all 272)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1119048061,2
    C--53526062(+) AAAAATACT/-  
            
    TACTT
    2 -- ut311Minor allele frequency- -:0.50CSA 2
    rs3710043891,2
    C--53526064(+) ACTTA-/CTTA  
            
    CTTAA
    4 -- ut310--------
    rs38642461,2
    --53526093(+) AATAAC/TTTGGA 2 -- ut310--------
    rs40021621,2
    --53526136(-) ACTTCG/TGTCAG 2 -- ut31 ese30--------
    rs1501270201,2
    C--53526172(+) CAAACC/GCTGCT 2 -- ut310--------
    rs39562811,2
    --53526242(-) TGCCTG/TAAGAG 2 -- ut31 ese30--------
    rs28924381,2
    --53526302(-) TGCACC/TATGCA 2 -- ut31 ese30--------
    rs1458471181,2
    C,F--53526365(+) CTGTAC/TTGAGC 4 I V mis12Minor allele frequency- T:0.00NA EU 5873
    rs169522721,2
    C,F,H--53526366(+) TGTACT/CGAGCC 4 /S syn1 ese310Minor allele frequency- C:0.01NA NS EA WA 5230
    rs2019815791,2
    C--53526377(+) AGGCTT/CTACCC 4 /K /E mis11Minor allele frequency- C:0.00EU 1323

    HapMap Linkage Disequilibrium report for AKTIP (53525192 - 53538323 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for AKTIP: --
    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 608483    OMIM disorders: --

    7 diseases for AKTIP:    About MalaCards
    balanitis xerotica obliterans    thymic hyperplasia    balanitis    thymoma
    cervical cancer    ovarian cancer    cervicitis

    1 disease from the University of Copenhagen DISEASES database for AKTIP:
    Balanitis xerotica obliterans

    AKTIP for disorders           About GeneDecksing

    Genetic Association Database (GAD): AKTIP
    Human Genome Epidemiology (HuGE) Navigator: AKTIP (3 documents)

    Export disorders for AKTIP gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for AKTIP gene, integrated from 9 sources (see all 21):
    (articles sorted by number of sources associating them with AKTIP)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Association between AKT1 but not AKTIP genetic varian ts and increased risk for suicidal behavior in bipolar patients. (PubMed id 20132317)1, 4 Magno L.A....Romano-Silva M.A. (2010)
    2. Functional complementation studies identify candidate genes and common genetic variants associated with ovarian cancer survival. (PubMed id 19270026)1, 4 Quaye L....Gayther S.A. (2009)
    3. An FTS/Hook/p107(FHIP) complex interacts with and promotes endosomal clustering by the homotypic vacuolar protein sorting complex. (PubMed id 18799622)1, 2 Xu L....Harper J.W. (2008)
    4. Regulation of apoptosis by the Ft1 protein, a new modulator of protein kinase B/Akt. (PubMed id 14749367)1, 2 Remy I. and Michnick S.W. (2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    7. A cDNA encoding the calcitonin gene-related peptide type 1 receptor. (PubMed id 8626685)1, 3 Aiyar N.... Li Y. (1996)
    8. Ft1, a novel gene related to ubiquitin-conjugating enzymes, is deleted in the Fused toes mouse mutation. (PubMed id 9383278)1, 9 Lesche R....Ruther U. (1997)
    9. Fused Toes Homolog modulates radiation cytotoxicity i n uterine cervical cancer cells. (PubMed id 21424602)1 Anandharaj A....Park W.Y. (2011)
    10. FTS (fused toes homolog) a novel oncoprotein involved in uterine cervical carcinogenesis and a potential diagnostic marker for cervi cal cancer. (PubMed id 20945372)1 Cinghu S....Park W.Y. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 64400 HGNC: 16710 AceView: FTS Ensembl:ENSG00000166971 euGenes: HUgn64400
    ECgene: AKTIP H-InvDB: AKTIP

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for AKTIP Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for AKTIP gene:
    Search GeneIP for patents involving AKTIP

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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