Aliases for AKT1S1 Gene
Aliases for AKT1S1 Gene
External Ids for AKT1S1 Gene
- HGNC: 28426
- Entrez Gene: 84335
- Ensembl: ENSG00000204673
- OMIM: 610221
- UniProtKB: Q96B36
Previous GeneCards Identifiers for AKT1S1 Gene
- GC19M055067
- GC19M055071
- GC19M055073
- GC19M050372
- GC19M046748
Summaries for AKT1S1 Gene
-
AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]).[supplied by OMIM, Mar 2008]
GeneCards Summary for AKT1S1 Gene
AKT1S1 (AKT1 Substrate 1) is a Protein Coding gene. Diseases associated with AKT1S1 include Diaphragmatic Eventration. Among its related pathways are Constitutive Signaling by AKT1 E17K in Cancer and RET signaling.
UniProtKB/Swiss-Prot for AKT1S1 Gene
-
Subunit of mTORC1, which regulates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino acids. Growth factor-stimulated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1. Amino acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases. Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E). mTORC1 phosphorylates and activates S6K1 at Thr-389, which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for degradation. Within mTORC1, AKT1S1 negatively regulates mTOR activity in a manner that is dependent on its phosphorylation state and binding to 14-3-3 proteins. Inhibits RHEB-GTP-dependent mTORC1 activation. Substrate for AKT1 phosphorylation, but can also be activated by AKT1-independent mechanisms. May also play a role in nerve growth factor-mediated neuroprotection.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AKT1S1 Gene
Genomics for AKT1S1 Gene
Regulatory Elements for AKT1S1 Gene
Enhancers for AKT1S1 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around AKT1S1 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the AKT1S1 gene promoter:
Regulatory Element Products
Genomic Location for AKT1S1 Gene
- Chromosome:
- 19
- Start:
- 49,869,033 bp from pter
- End:
- 49,878,459 bp from pter
- Size:
- 9,427 bases
- Orientation:
- Minus strand
Genomic View for AKT1S1 Gene
Genes around AKT1S1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.33 by Ensembl
- 19q13.33 by Entrez Gene
- 19q13.33 by HGNC
AKT1S1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for AKT1S1 Gene
Proteins for AKT1S1 Gene
-
Protein details for AKT1S1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96B36-AKTS1_HUMAN
- Recommended name:
- Proline-rich AKT1 substrate 1
- Protein Accession:
- Q96B36
- A8MTQ1
- B2RE93
- J3KPM3
- Q96BI4
- Q96IK7
- Q96NG2
- Q9BWR5
Protein attributes for AKT1S1 Gene
- Size:
- 256 amino acids
- Molecular mass:
- 27383 Da
- Quaternary structure:
-
- Part of the mammalian target of rapamycin complex 1 (mTORC1) which contains MTOR, MLST8, RPTOR, AKT1S1/PRAS40 and DEPTOR. mTORC1 binds to and is inhibited by FKBP12-rapamycin. Interacts directly with RPTOR. The phosphorylated form interacts with 14-3-3 proteins.
- SequenceCaution:
-
- Sequence=AAH00031.2; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for AKT1S1 Gene
Post-translational modifications for AKT1S1 Gene
- Phosphorylated by AKT1 (PubMed:12524439). Phosphorylation at Thr-246 by DYRK3 relieves inhibitory function on mTORC1 (PubMed:23415227).
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for AKT1S1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for AKT1S1
- R&D Systems Antibodies for AKT1S1 (PRAS40)
- Cell Signaling Technology (CST) Antibodies for AKT1S1 (PRAS40)
-
Custom Antibody ServicesOriGene Antibodies for AKT1S1
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- Invitrogen Antibodies for AKT1S1
- antibodies-online Antibodies for AKT1S1: See all 92
- GeneTex AKT1S1 antibody for AKT1S1
-
Custom Antibody ServicesProSci Antibodies for AKT1S1
-
Santa Cruz Biotechnology (SCBT) Antibodies for AKT1S1
Protein Products
- Enzo Life Sciences proteins for AKT1S1
-
OriGene Purified Proteins for AKT1S1
- Search Origene for MassSpec and Protein Over-expression Lysates for AKT1S1
- Origene Custom Protein Services for AKT1S1
- antibodies-online Proteins for AKT1S1: See all 5
- Search antibodies-online for peptides
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Assay Products
- EMD Millipore Kits and Assays for AKT1S1
- R&D Systems Proteome Profiler Antibody Arrays and other biochemical assays for AKT1S1 (PRAS40)
- Cell Signaling Technology (CST) Sandwich ELISA Kits for AKT1S1 (PRAS40)
- antibodies-online Kits for AKT1S1: See all 13
No data available for DME Specific Peptides for AKT1S1 Gene
Domains & Families for AKT1S1 Gene
Gene Families for AKT1S1 Gene
- HGNC:
Suggested Antigen Peptide Sequences for AKT1S1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for AKT1S1 Gene
Function for AKT1S1 Gene
Molecular function for AKT1S1 Gene
- UniProtKB/Swiss-Prot Function:
- Subunit of mTORC1, which regulates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino acids. Growth factor-stimulated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1. Amino acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases. Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E). mTORC1 phosphorylates and activates S6K1 at Thr-389, which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for degradation. Within mTORC1, AKT1S1 negatively regulates mTOR activity in a manner that is dependent on its phosphorylation state and binding to 14-3-3 proteins. Inhibits RHEB-GTP-dependent mTORC1 activation. Substrate for AKT1 phosphorylation, but can also be activated by AKT1-independent mechanisms. May also play a role in nerve growth factor-mediated neuroprotection.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 12524439 |
Phenotypes for AKT1S1 Gene
- MGI mutant phenotypes for AKT1S1:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for AKT1S1:
Animal Models for AKT1S1 Gene
- MGI Knock Outs for AKT1S1:
-
- Akt1s1 tm1.1Rrth
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for AKT1S1
-
-
ViGene Biosciences lentiviral particle packaged cDNA for AKT1S1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for AKT1S1 gene
- Search ViGene Biosciences for AKT1S1
CRISPR Products
-
OriGene CRISPR knockouts for AKT1S1
-
Santa Cruz Biotechnology (SCBT) CRISPR for AKT1S1
- GenScript: Design CRISPR guide RNA sequences for AKT1S1
miRNA for AKT1S1 Gene
- miRTarBase miRNAs that target AKT1S1
miRNA Products
- Search ViGene Biosciences for AKT1S1
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for AKT1S1
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-
ViGene Biosciences ready-to-package AAV shRNAs for AKT1S1 gene
Clone Products
- Sino Biological Human cDNA Clone for AKT1S1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for AKT1S1
- VectorBuilder custom plasmid, inducible vectors for AKT1S1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for AKT1S1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for AKT1S1
-
ViGene Biosciences adenoviral particle packaged cDNA for AKT1S1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for AKT1S1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for AKT1S1 gene
Flow Cytometry Products
- eBioscience FlowRNA Probe Sets (VA4-13581) for AKT1S1
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for AKT1S1 Gene
Localization for AKT1S1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for AKT1S1 Gene
- Cytoplasm, cytosol. Note=Found in the cytosolic fraction of the brain. {ECO:0000250}.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 5 |
| extracellular | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005737 | cytoplasm | IBA,IEA | -- |
| GO:0005829 | cytosol | TAS | -- |
| GO:0031931 | colocalizes_with TORC1 complex | IDA | 17386266 |
Pathways & Interactions for AKT1S1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | RET signaling |
.92
|
|
| 2 | GAB1 signalosome |
.89
|
|
| 3 | mTOR signalling |
.70
|
.51
|
| 4 | AMP-activated Protein Kinase (AMPK) Signaling | ||
| 5 | Longevity regulating pathway | ||
Pathways by source for AKT1S1 Gene
4 Sino Biological pathways for AKT1S1 Gene
1 GeneTex pathway for AKT1S1 Gene
2 Cell Signaling Technology pathways for AKT1S1 Gene
37 Reactome pathways for AKT1S1 Gene
5 KEGG pathways for AKT1S1 Gene
4 R&D Systems pathways for AKT1S1 Gene
2 Qiagen pathways for AKT1S1 Gene
Interacting Proteins for AKT1S1 Gene
Selected Interacting proteins:
Q96B36-AKTS1_HUMAN
ENSP00000341698
for AKT1S1 Gene via
IID
STRING
MINT
UniProtKB
SIGNOR curated interactions for AKT1S1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006469 | negative regulation of protein kinase activity | IDA | 17386266 |
| GO:0032007 | negative regulation of TOR signaling | IDA | 17386266 |
| GO:0038202 | TORC1 signaling | IBA | -- |
| GO:0042981 | regulation of apoptotic process | ISS | -- |
| GO:0043523 | regulation of neuron apoptotic process | ISS | -- |
Transcripts for AKT1S1 Gene
mRNA/cDNA for AKT1S1 Gene
- (5) REFSEQ mRNAs :
- (11) Additional mRNA sequences :
- (756) Selected AceView cDNA sequences:
- (9) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for AKT1S1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for AKT1S1
-
Santa Cruz Biotechnology (SCBT) CRISPR for AKT1S1
- GenScript: Design CRISPR guide RNA sequences for AKT1S1
miRNA Products
- Search ViGene Biosciences for AKT1S1
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for AKT1S1
- Browse OriGene Inhibitory RNA Products For AKT1S1
-
ViGene Biosciences ready-to-package AAV shRNAs for AKT1S1 gene
Clone Products
- Sino Biological Human cDNA Clone for AKT1S1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for AKT1S1
- VectorBuilder custom plasmid, inducible vectors for AKT1S1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for AKT1S1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
- eBioscience FlowRNA Probe Sets (VA4-13581) for AKT1S1
Expression for AKT1S1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Limb (Muscoskeletal System)
- Limb Muscle Progenitor Cells Forelimb Myotome
-
Skeletal Muscle (Muscoskeletal System)
- Limb Muscle Progenitor Cells Forelimb Myotome
This gene is overexpressed in Adrenal (22.8), Bone marrow stromal cell (12.0), and Lung (8.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for AKT1S1 Gene
NURSA nuclear receptor signaling pathways regulating expression of AKT1S1 Gene:
AKT1S1SOURCE GeneReport for Unigene cluster for AKT1S1 Gene:
Hs.515542mRNA Expression by UniProt/SwissProt for AKT1S1 Gene:
Q96B36-AKTS1_HUMAN
Tissue specificity:
Widely expressed with highest levels of expression in liver and heart. Expressed at higher levels in cancer cell lines (e.g. A-549 and HeLa) than in normal cell lines (e.g. HEK293).
Evidence on tissue expression from TISSUES for AKT1S1 Gene
- Liver(4.5)
- Nervous system(3.8)
- Skin(3)
- Lung(2.6)
- Muscle(2.3)
Primer Products
-
OriGene qPCR primer pairs for AKT1S1
-
OriGene qPCR primer pairs and template standards for AKT1S1
No data available for mRNA differential expression in normal tissues , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for AKT1S1 Gene
Orthologs for AKT1S1 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | AKT1S1 35 34 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | AKT1S1 35 34 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | AKT1S1 35 34 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Akt1s1 16 35 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Akt1s1 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | AKT1S1 35 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | AKT1S1 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | akt1s1 34 |
|
||
| Str.8926 34 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.7177 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | akt1s1 35 |
|
OneToOne |
- Species where no ortholog for AKT1S1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for AKT1S1 Gene
No data available for Paralogs for AKT1S1 Gene
Variants for AKT1S1 Gene
| SNP ID | Clin | Chr 19 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000002352 | -- | 49,870,494(+) | AATGG(A/G)GCGGA | intron-variant | |
| rs1000415858 | -- | 49,875,615(+) | TCCAG(C/T)CCCTA | intron-variant, upstream-variant-2KB | |
| rs1000625191 | -- | 49,870,530(+) | ATAAT(C/T)AGCTG | intron-variant | |
| rs1000990353 | -- | 49,869,609(+) | TAGGC(-/G)GAAAA | utr-variant-3-prime | |
| rs1001273441 | -- | 49,869,765(+) | AGGAC(A/G)GCGGG | utr-variant-3-prime |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv53n68 | CNV | loss | 17160897 |
| dgv54n68 | CNV | loss | 17160897 |
| esv2718724 | CNV | deletion | 23290073 |
| esv2718725 | CNV | deletion | 23290073 |
| esv3644628 | CNV | gain | 21293372 |
| esv3644630 | CNV | gain | 21293372 |
| nsv1111553 | CNV | deletion | 24896259 |
| nsv1121196 | CNV | deletion | 24896259 |
| nsv1140251 | OTHER | inversion | 24896259 |
| nsv1152384 | CNV | deletion | 26484159 |
| nsv138068 | CNV | deletion | 16902084 |
| nsv2519 | CNV | deletion | 18451855 |
| nsv524068 | CNV | loss | 19592680 |
| nsv526372 | CNV | loss | 19592680 |
| nsv953600 | CNV | deletion | 24416366 |
| nsv9739 | CNV | gain+loss | 18304495 |
Gene Damage Index Score:
1.17;
23.65% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for AKT1S1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- AKT1S1
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for AKT1S1 Gene
Disorders for AKT1S1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| diaphragmatic eventration |
|
|
Search AKT1S1 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for AKT1S1
No data available for UniProtKB/Swiss-Prot and Genatlas for AKT1S1 Gene
Publications for AKT1S1 Gene
- Identification of a proline-rich Akt substrate as a 14-3-3 binding partner. (PMID: 12524439) Kovacina K.S. … Roth R.A. (J. Biol. Chem. 2003) 2 3 4 64
- Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40. (PMID: 17277771) Vander Haar E. … Kim D.-H. (Nat. Cell Biol. 2007) 3 4 64
- PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase. (PMID: 17386266) Sancak Y. … Sabatini D.M. (Mol. Cell 2007) 3 4 64
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3 4 64
- Expression of proline-rich Akt-substrate PRAS40 in cell survival pathway and carcinogenesis. (PMID: 16174443) Huang B. … Porter G. (Acta Pharmacol. Sin. 2005) 3 4 64
Products for AKT1S1 Gene
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- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for AKT1S1
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- EMD Millipore Kits and Assays for AKT1S1
- EMD Millipore genomic analysis products
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- Custom Antibody ServicesOriGene Antibodies for AKT1S1
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- Search for Antibodies & Assays
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- Novus Biologicals Antibodies for AKT1S1
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- Addgene plasmids for AKT1S1
- antibodies-online Antibodies for AKT1S1: See all 92
- antibodies-online Kits for AKT1S1: See all 13
- antibodies-online Proteins for AKT1S1: See all 5
- Search antibodies-online for peptides
- GeneTex AKT1S1 antibody for AKT1S1
- Search GeneTex for Proteins for AKT1S1
- ViGene Biosciences adenoviral particle packaged cDNA for AKT1S1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for AKT1S1 gene
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- Search ViGene Biosciences for AKT1S1
- Santa Cruz Biotechnology (SCBT) Antibodies for AKT1S1
- Search Santa Cruz Biotechnology (SCBT) for AKT1S1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for AKT1S1
- Custom Antibody ServicesProSci Antibodies for AKT1S1
- Search for AKT1S1 Proteins at ProSci
- Horizon Cell Lines for AKT1S1
- Cyagen custom Knockout/knockin (KOKI) mouse models for AKT1S1
- VectorBuilder custom plasmid, inducible vectors for AKT1S1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for AKT1S1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for AKT1S1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
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