Aliases for AKR7A3 Gene
External Ids for AKR7A3 Gene
Previous GeneCards Identifiers for AKR7A3 Gene
Aldo-keto reductases, such as AKR7A3, are involved in the detoxification of aldehydes and ketones.[supplied by OMIM, Apr 2004]
GeneCards Summary for AKR7A3 Gene
AKR7A3 (Aldo-Keto Reductase Family 7, Member A3 (Aflatoxin Aldehyde Reductase)) is a Protein Coding gene. Diseases associated with AKR7A3 include pancreas adenocarcinoma and babesiosis. Among its related pathways are Metabolism of xenobiotics by cytochrome P450 and Aflatoxin activation and detoxification. GO annotations related to this gene include electron carrier activity and aldo-keto reductase (NADP) activity. An important paralog of this gene is KCNAB1.
UniProtKB/Swiss-Prot for AKR7A3 Gene
Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.