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Aliases for AKNAD1 Gene

Aliases for AKNAD1 Gene

  • AKNA Domain Containing 1 2 3
  • C1orf62 3 4
  • Chromosome 1 Open Reading Frame 62 2
  • Protein AKNAD1 3

External Ids for AKNAD1 Gene

Previous Symbols for AKNAD1 Gene

  • C1orf62

Summaries for AKNAD1 Gene

Entrez Gene Summary for AKNAD1 Gene

  • This gene encodes a protein which contains a domain found in an AT-hook-containing transcription factor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012]

GeneCards Summary for AKNAD1 Gene

AKNAD1 (AKNA Domain Containing 1) is a Protein Coding gene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AKNAD1 Gene

Genomics for AKNAD1 Gene

Genomic Location for AKNAD1 Gene

Start:
108,815,898 bp from pter
End:
108,858,242 bp from pter
Size:
42,345 bases
Orientation:
Minus strand

Genomic View for AKNAD1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for AKNAD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for AKNAD1 Gene

No data available for Regulatory Elements for AKNAD1 Gene

Proteins for AKNAD1 Gene

  • Protein details for AKNAD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T1N1-AKND1_HUMAN
    Recommended name:
    Protein AKNAD1
    Protein Accession:
    Q5T1N1
    Secondary Accessions:
    • B9EK62
    • Q5T1N0
    • Q8N990
    • Q8NCN9

    Protein attributes for AKNAD1 Gene

    Size:
    836 amino acids
    Molecular mass:
    92864 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for AKNAD1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for AKNAD1 Gene

Proteomics data for AKNAD1 Gene at MOPED

Post-translational modifications for AKNAD1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for AKNAD1 Gene

No data available for DME Specific Peptides for AKNAD1 Gene

Domains for AKNAD1 Gene

Protein Domains for AKNAD1 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

AKND1_HUMAN
Family:
  • Belongs to the AKNA family.:
    • Q5T1N1
genes like me logo Genes that share domains with AKNAD1: view

No data available for Gene Families for AKNAD1 Gene

Function for AKNAD1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for AKNAD1 Gene

Localization for AKNAD1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for AKNAD1 Gene COMPARTMENTS Subcellular localization image for AKNAD1 gene
Compartment Confidence
cytosol 4
nucleus 3

Gene Ontology (GO) - Cellular Components for AKNAD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IDA --
genes like me logo Genes that share ontologies with AKNAD1: view

Pathways for AKNAD1 Gene

SuperPathways for AKNAD1 Gene

No Data Available

Interacting Proteins for AKNAD1 Gene

Gene Ontology (GO) - Biological Process for AKNAD1 Gene

None

No data available for Pathways by source for AKNAD1 Gene

Transcripts for AKNAD1 Gene

mRNA/cDNA for AKNAD1 Gene

Unigene Clusters for AKNAD1 Gene

AKNA domain containing 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for AKNAD1 Gene

ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10 ^ 11a · 11b ^ 12a · 12b ^ 13 ^ 14a · 14b ^ 15 ^ 16 ^ 17a ·
SP1: - - - - -
SP2: - - - - - - - - - - - -
SP3:
SP4:
SP5: -
SP6:

ExUns: 17b ^ 18
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:

Relevant External Links for AKNAD1 Gene

GeneLoc Exon Structure for
AKNAD1
ECgene alternative splicing isoforms for
AKNAD1

Expression for AKNAD1 Gene

mRNA expression in normal human tissues for AKNAD1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for AKNAD1 Gene

This gene is overexpressed in Testis (28.4).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for AKNAD1 Gene

SOURCE GeneReport for Unigene cluster for AKNAD1 Gene Hs.729441

genes like me logo Genes that share expressions with AKNAD1: view

Orthologs for AKNAD1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for AKNAD1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 37
  • 98 (a)
OneToMany
-- 37
  • 45 (a)
OneToMany
AKNAD1 36
  • 98.92 (n)
  • 97.85 (a)
cow
(Bos Taurus)
Mammalia AKNAD1 36
  • 79.35 (n)
  • 63.28 (a)
AKNAD1 37
  • 59 (a)
OneToOne
dog
(Canis familiaris)
Mammalia AKNAD1 36
  • 79.84 (n)
  • 67.73 (a)
AKNAD1 37
  • 63 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Aknad1 36
  • 70.59 (n)
  • 54.93 (a)
Aknad1 16
Aknad1 37
  • 54 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia AKNAD1 37
  • 29 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia AKNAD1 37
  • 36 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Aknad1 36
  • 72 (n)
  • 54.79 (a)
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 28 (a)
OneToMany
-- 37
  • 54 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii AKNAD1 37
  • 23 (a)
OneToOne
Species with no ortholog for AKNAD1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for AKNAD1 Gene

ENSEMBL:
Gene Tree for AKNAD1 (if available)
TreeFam:
Gene Tree for AKNAD1 (if available)

Paralogs for AKNAD1 Gene

No data available for Paralogs for AKNAD1 Gene

Variants for AKNAD1 Gene

Sequence variations from dbSNP and Humsavar for AKNAD1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs868939 -- 108,847,591(-) CATAC(A/G)GCACT intron-variant
rs868940 -- 108,847,578(-) GGAGC(A/G)CGTGG intron-variant
rs914809 -- 108,845,441(+) TGACA(A/G)CTGCT intron-variant
rs914810 -- 108,846,959(+) atcca(A/G)gcctc intron-variant
rs946242 -- 108,834,431(-) GCAGC(C/T)GGGGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for AKNAD1 Gene

Variant ID Type Subtype PubMed ID
nsv2287 CNV Loss 18451855
nsv463106 CNV Loss 19166990
nsv526819 CNV Loss 19592680
nsv521427 CNV Loss 19592680
dgv63n67 CNV Loss 20364138
esv7631 CNV Loss 19470904
esv2715929 CNV Deletion 23290073
esv2670634 CNV Deletion 23128226
esv26096 CNV Loss 19812545
esv2421353 CNV Deletion 20811451
nsv463117 CNV Loss 19166990
nsv818322 CNV Loss 17921354
nsv517381 CNV Loss 19592680
nsv823943 CNV Loss 20364138

Relevant External Links for AKNAD1 Gene

HapMap Linkage Disequilibrium report
AKNAD1

Disorders for AKNAD1 Gene

Relevant External Links for AKNAD1

Genetic Association Database (GAD)
AKNAD1
Human Genome Epidemiology (HuGE) Navigator
AKNAD1
genes like me logo Genes that share disorders with AKNAD1: view

No data available for UniProtKB/Swiss-Prot for AKNAD1 Gene

Publications for AKNAD1 Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 49
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for AKNAD1 Gene

Sources for AKNAD1 Gene

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