Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



AKIRIN1 Gene

protein-coding   GIFtS: 44
GCID: GC01P039456

Akirin 1

(Previous name: chromosome 1 open reading frame 108)
(Previous symbol: C1orf108)
  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Akirin 11 2
C1orf1081 2 3
Chromosome 1 Open Reading Frame 1081
STRF22
akirin-12

External Ids:    HGNC: 257441   Entrez Gene: 796472   Ensembl: ENSG000001745747   OMIM: 6151645   UniProtKB: Q9H9L73   

Export aliases for AKIRIN1 gene to outside databases

Previous GC identifers: GC01P039230 GC01P037576


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for AKIRIN1 Gene:
AKIRIN1 (akirin 1) is a protein-coding gene. An important paralog of this gene is AKIRIN2.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NC_018912.2  NT_032977.10  
Regulatory elements:
   Regulatory transcription factor binding sites in the AKIRIN1 gene promoter:
         Sp1   AML1a   SREBP-1c   NF-AT   SREBP-1b   CREB   NF-AT2   SREBP-1a   deltaCREB   NF-AT1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidAKIRIN1 promoter sequence
   Search Chromatin IP Primers for AKIRIN1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat AKIRIN1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p34.3   Ensembl cytogenetic band:  1p34.3   HGNC cytogenetic band: 1p34.3

AKIRIN1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AKIRIN1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P039456:  view genomic region     (about GC identifiers)

Start:
39,456,895 bp from pter      End:
39,471,737 bp from pter
Size:
14,843 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: AKIR1_HUMAN, Q9H9L7 (See protein sequence)
Recommended Name: Akirin-1  
Size: 192 amino acids; 21867 Da
Miscellaneous: 'Akiraka ni suru' means 'making things clear' in Japanese. The name is given based on the presence
of the clear nuclear localization signal
Sequence caution: Sequence=AAI19747.1; Type=Erroneous initiation;
Secondary accessions: B4DZU6 Q0VDB3 Q53FK8
Alternative splicing: 2 isoforms:  Q9H9L7-1   Q9H9L7-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for AKIRIN1: NX_Q9H9L7

Explore proteomics data for AKIRIN1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See AKIRIN1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001129747.1  NP_078871.1  

    ENSEMBL proteins: 
     ENSP00000392678   ENSP00000389866   ENSP00000362075   ENSP00000436372  

    AKIRIN1 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec
    OriGene Custom Protein Services for AKIRIN1
    GenScript Custom Purified and Recombinant Proteins Services for AKIRIN1
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for AKIRIN1

     
    Search eBioscience for Proteins for AKIRIN1 

     
    antibodies-online proteins for AKIRIN1 (4 products) 

     
    antibodies-online peptides for AKIRIN1

    AKIRIN1 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for AKIRIN1
    OriGene Custom Antibody Services for AKIRIN1
    Novus Biologicals AKIRIN1 Antibody
    Abcam antibodies for AKIRIN1
    Cloud-Clone Corp. Antibodies for AKIRIN1
    ThermoFisher Antibodies for AKIRIN1
    antibodies-online antibodies for AKIRIN1 (44 products) 

    AKIRIN1 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for AKIRIN1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for AKIRIN1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for AKIRIN1
    Cloud-Clone Corp. CLIAs for AKIRIN1
    Search eBioscience for ELISAs for AKIRIN1 
    antibodies-online kits for AKIRIN1 (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    1 InterPro protein domain:
     IPR024132 Akirin

    Graphical View of Domain Structure for InterPro Entry Q9H9L7

    ProtoNet protein and cluster: Q9H9L7

    UniProtKB/Swiss-Prot: AKIR1_HUMAN, Q9H9L7
    Similarity: Belongs to the akirin family


    Find genes that share domains with AKIRIN1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Phenotypes:
         1 GenomeRNAi human phenotype for AKIRIN1:
     Increased gamma-H2AX phosphory 

         2 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Akirin1):
     no phenotypic analysis  normal 

    Find genes that share phenotypes with AKIRIN1           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Akirin1tm1.1Aki for AKIRIN1

       genOway: Develop your customized and physiologically relevant rodent model for AKIRIN1

    miRNA
    Products:
        
    miRTarBase miRNAs that target AKIRIN1:
    hsa-mir-331-3p (MIRT043549)

    Block miRNA regulation of human, mouse, rat AKIRIN1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate AKIRIN1 (see all 35):
    hsa-miR-3910 hsa-miR-100* hsa-miR-520d-5p hsa-miR-181c hsa-miR-2110 hsa-miR-373* hsa-miR-3116 hsa-miR-1255a
    SwitchGear 3'UTR luciferase reporter plasmidAKIRIN1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for AKIRIN1
    Predesigned siRNA for gene silencing in human, mouse, rat AKIRIN1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for AKIRIN1

    Clone
    Products:
         
    OriGene clones in human, mouse for AKIRIN1 (see all 9)
    OriGene ORF clones in mouse, rat for AKIRIN1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): AKIRIN1 (NM_001136275)
    Sino Biological Human cDNA Clone for AKIRIN1
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for AKIRIN1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AKIRIN1

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for AKIRIN1
    Browse ESI BIO Cell Lines and PureStem Progenitors for AKIRIN1 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AKIRIN1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    AKIR1_HUMAN, Q9H9L7: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0031965nuclear membrane IDA--
    GO:0043231intracellular membrane-bounded organelle ----

    Find genes that share ontologies with AKIRIN1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus




        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for AKIRIN1
    Interactions:

        Search GeneGlobe Interaction Network for AKIRIN1

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    5 Interacting proteins for AKIRIN1 (Q9H9L73 ENSP000003926784) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DYNC2LI1Q8TCX13I2D: score=5 
    KLC1Q078663I2D: score=5 
    PAPLNO954283I2D: score=5 
    SMARCD1Q96GM53I2D: score=5 
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for AKIRIN1 (AKIR1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for AKIRIN1 gene (2 alternative transcripts): 
    NM_001136275.1  NM_024595.2  

    Unigene Cluster for AKIRIN1:

    Akirin 1
    Hs.293563  [show with all ESTs]
    Unigene Representative Sequence: NM_024595
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000432648(uc001ccw.3 uc010oip.2 uc010oiq.2) ENST00000446189
    ENST00000372984 ENST00000531822
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat AKIRIN1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate AKIRIN1 (see all 35):
    hsa-miR-3910 hsa-miR-100* hsa-miR-520d-5p hsa-miR-181c hsa-miR-2110 hsa-miR-373* hsa-miR-3116 hsa-miR-1255a
    SwitchGear 3'UTR luciferase reporter plasmidAKIRIN1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for AKIRIN1
    Predesigned siRNA for gene silencing in human, mouse, rat AKIRIN1
    Clone
    Products:
         
    OriGene clones in human, mouse for AKIRIN1 (see all 9)
    OriGene ORF clones in mouse, rat for AKIRIN1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): AKIRIN1 (NM_001136275)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for AKIRIN1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AKIRIN1
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for AKIRIN1
    OriGene qSTAR qPCR primer pairs in human, mouse for AKIRIN1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat AKIRIN1
      QuantiTect SYBR Green Assays in human, mouse, rat AKIRIN1
      QuantiFast Probe-based Assays in human, mouse, rat AKIRIN1

    Additional mRNA sequence: 

    AK022728.1 AK092624.1 AK124799.1 AK126262.1 AK223276.1 AK298890.1 AK303098.1 AY326465.1 
    BC001498.2 BC119745.1 BC119746.1 

    18 DOTS entries:

    DT.95152979  DT.87016446  DT.100826819  DT.91937982  DT.97766397  DT.102828415  DT.99986143  DT.87016445 
    DT.91692622  DT.95148844  DT.121341191  DT.121341200  DT.92452135  DT.95153431  DT.95153433  DT.95234642 
    DT.97760259  DT.99928603 

    Selected AceView cDNA sequences (see all 304):

    AW173705 BU150388 BQ894127 CA419610 AI655470 BE891280 BM993709 AW080242 
    CK905949 BI087307 BF062683 BE883055 BM452247 BC001498 CA413087 BQ013031 
    BQ270549 BG109865 F06810 BQ272318 AI077696 BQ680831 BQ719984 BU553678 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    AKIRIN1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTCAACTGCT
    AKIRIN1 Expression
    About this image

    AKIRIN1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    AKIRIN1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.293563

    UniProtKB/Swiss-Prot: AKIR1_HUMAN, Q9H9L7
    Tissue specificity: Widely expressed with the highest expression in heart, liver, placenta and peripheral blood
    leukocytes

        Custom PCR Arrays for AKIRIN1
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for AKIRIN1
    OriGene qSTAR qPCR primer pairs in human, mouse for AKIRIN1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat AKIRIN1
    QuantiTect SYBR Green Assays in human, mouse, rat AKIRIN1
    QuantiFast Probe-based Assays in human, mouse, rat AKIRIN1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AKIRIN1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for AKIRIN1 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Akirin11 , 5 akirin 11, 5 88.13(n)1
    91.1(a)1
      4 (57.42 cM)5
    680501  NM_023423.31  NP_075912.21 
     1237345595 
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.42042 Xenopus laevis transcribed sequence with weak similarity more 77.6(n)    CA793363.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufa96c112 Danio rerio cDNA clone MGC64050 IMAGE6793742, complete more 74.49(n)    BC053224.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta akirin6
    akirin
    33(a)
    1 → many
    3L(7362943-7366811)


    ENSEMBL Gene Tree for AKIRIN1 (if available)
    TreeFam Gene Tree for AKIRIN1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for AKIRIN1 gene
    AKIRIN22  
    1 SIMAP similar gene for AKIRIN1 using alignment to 3 protein entries:     AKIR1_HUMAN (see all proteins):
    AKIRIN2

    Find genes that share paralogs with AKIRIN1           About GenesLikeMe


    4 Pseudogenes.org Pseudogenes for AKIRIN1
    PGOHUM00000239529 PGOHUM00000241134 PGOHUM00000246099 PGOHUM00000241824


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for AKIRIN1 (see all 356)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs729408051,2
    C,F--39454978(+) TTTGTT/CGTTAA 2 -- us2k15Minor allele frequency- C:0.16WA CSA 125
    rs1472363591,2
    --39455196(+) TCTTTC/TTTTTT 2 -- us2k10--------
    rs1483343361,2
    --39455329(+) ACCACA/GCCTGG 2 -- us2k10--------
    rs127561401,2
    C,F--39455426(+) CTCGGT/CCTCCA 2 -- us2k14Minor allele frequency- C:0.38NA WA CSA 8
    rs1505730301,2
    --39455446(+) GATTAC/TAGGCG 2 -- us2k10--------
    rs1151147741,2
    C,F--39455461(+) CCACCG/ACACCC 2 -- us2k11Minor allele frequency- A:0.04WA 118
    rs127562551,2
    C,F,H--39455470(+) ccagcC/TGATAA 2 -- us2k111Minor allele frequency- T:0.02NS EA NA 1556
    rs1913021091,2
    --39455490(+) AAATTC/GAGTTA 2 -- us2k10--------
    rs75328071,2
    C,F,A,H--39455542(+) TCTGGC/GCCTAA 2 -- us2k19Minor allele frequency- G:0.17NS EA NA WA 774
    rs758514691,2
    C--39455571(+) CTAGCC/TTATTG 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for AKIRIN1 (39456895 - 39471737 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for AKIRIN1: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing AKIRIN1
    DNA2.0 Custom Variant and Variant Library Synthesis for AKIRIN1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 615164    OMIM disorders: --


    Find genes that share disorders with AKIRIN1           About GenesLikeMe


    Export disorders for AKIRIN1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for AKIRIN1 gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with AKIRIN1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Evolution of the multifaceted eukaryotic akirin gene family. (PubMed id 19200367)1, 3 Macqueen D.J. and Johnston I.A. (BMC Evol. Biol. 2009)
    2. Akirins are highly conserved nuclear proteins required for NF-kappaB- dependent gene expression in Drosophila and mice. (PubMed id 18066067)1, 2 Goto A.... Reichhart J.-M. (Nat. Immunol. 2008)
    3. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)
    7. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (EMBO J. 2009)
    8. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008)
    9. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 79647 HGNC: 25744 AceView: FLJ12666 Ensembl:ENSG00000174574 euGenes: HUgn79647
    ECgene: AKIRIN1 H-InvDB: AKIRIN1

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for AKIRIN1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for AKIRIN1 gene:
    Search GeneIP for patents involving AKIRIN1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for AKIRIN1   OriGene RNAi products in human, mouse, rat for AKIRIN1  
     OriGene qPCR primer pairs and template standards for AKIRIN1   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for AKIRIN1  
     OriGene qSTAR qPCR primer pairs in human, mouse for AKIRIN1   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for AKIRIN1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for AKIRIN1   OriGene Custom Protein Services for AKIRIN1  

     
     
     Block miRNA regulation of human, mouse, rat AKIRIN1 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing AKIRIN1
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat AKIRIN1 Predesigned siRNA for gene silencing in human, mouse, rat AKIRIN1
     QuantiFast Probe-based Assays in human, mouse, rat AKIRIN1 QuantiTect SYBR Green Assays in human, mouse, rat AKIRIN1
     Custom PCR Arrays for AKIRIN1 Search Chromatin IP Primers for AKIRIN1
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat AKIRIN1  Search GeneGlobe Interaction Network for AKIRIN1
     Regulatory tfbs in AKIRIN1 promoter
     GenScript Custom Purified and Recombinant Proteins Services for AKIRIN1 GenScript cDNA clones with any tag delivered in your preferred vector for AKIRIN1
     GenScript Custom Assay Services for AKIRIN1 GenScript Custom overexpressing Cell Line Services for AKIRIN1
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for AKIRIN1 (AKIR1)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     cDNA Clones for AKIRIN1
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     AKIRIN1 antibodies
     Antibodies for AKIRIN1
     See all of Abcam's Antibodies, Kits and Proteins for AKIRIN1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for AKIRIN1
     Antibodies for AKIRIN1
     ELISAs for AKIRIN1
     CLIAs for AKIRIN1



     Browse ESI BIO Cell Lines and PureStem Progenitors for AKIRIN1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AKIRIN1
     SwitchGear 3'UTR luciferase reporter plasmids for AKIRIN1
     SwitchGear Promoter luciferase reporter plasmids for AKIRIN1
     ThermoFisher Antibodies for AKIRIN1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AKIRIN1
     Browse compounds at ApexBio
     Search Addgene for plasmids for AKIRIN1
      Search eBioscience for proteins for AKIRIN1
      Search eBioscience for elisas for AKIRIN1
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for AKIRIN1
     antibodies-online antibodies for AKIRIN1 (44 products)
     antibodies-online kits for AKIRIN1 (4 products)
     antibodies-online peptides for AKIRIN1
     antibodies-online proteins for AKIRIN1 (4 products)
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      AKIRIN1 gene at Home site.
    Version: 3.12.258 10 Dec 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4