Aliases for AKAP4 Gene
External Ids for AKAP4 Gene
Previous GeneCards Identifiers for AKAP4 Gene
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is localized to the sperm flagellum and may be involved in the regulation of sperm motility. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
GeneCards Summary for AKAP4 Gene
AKAP4 (A-Kinase Anchoring Protein 4) is a Protein Coding gene. Among its related pathways are Activation of cAMP-Dependent PKA and Signal transduction_PKA signaling. GO annotations related to this gene include protein kinase A binding. An important paralog of this gene is AKAP3.
UniProtKB/Swiss-Prot for AKAP4 Gene
Major structural component of sperm fibrous sheath. Plays a role in sperm motility.