Aliases for AKAP2 Gene
External Ids for AKAP2 Gene
Previous HGNC Symbols for AKAP2 Gene
Previous GeneCards Identifiers for AKAP2 Gene
The protein encoded by this gene binds to the regulatory subunit of protein kinase A and is found associated with the actin cytoskeleton. The encoded protein mediates signals carried by cAMP and may be involved in creating polarity in certain signaling processes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
GeneCards Summary for AKAP2 Gene
AKAP2 (A-Kinase Anchoring Protein 2) is a Protein Coding gene. Diseases associated with AKAP2 include Kallmann Syndrome. Among its related pathways are Proton Pump Inhibitor Pathway, Pharmacodynamics and DAG and IP3 signaling. An important paralog of this gene is PALM2-AKAP2.
UniProtKB/Swiss-Prot for AKAP2 Gene
Binds to regulatory subunit (RII) of protein kinase A. May be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream effectors to capture, amplify and focus diffuse, trans-cellular signals carried by cAMP (By similarity).