Aliases for AKAP11 Gene
External Ids for AKAP11 Gene
Previous GeneCards Identifiers for AKAP11 Gene
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed at high levels throughout spermatogenesis and in mature sperm. It binds the RI and RII subunits of PKA in testis. It may serve a function in cell cycle control of both somatic cells and germ cells in addition to its putative role in spermatogenesis and sperm function. [provided by RefSeq, Jul 2008]
GeneCards Summary for AKAP11 Gene
AKAP11 (A-Kinase Anchoring Protein 11) is a Protein Coding gene. Among its related pathways are Activation of cAMP-Dependent PKA and DAG and IP3 signaling. GO annotations related to this gene include protein kinase A binding and protein phosphatase 1 binding. An important paralog of this gene is SPHKAP.
UniProtKB/Swiss-Prot for AKAP11 Gene
Binds to type II regulatory subunits of protein kinase A and anchors/targets them.