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AKAP11 Gene

protein-coding   GIFtS: 60
GCID: GC13P042846

A Kinase (PRKA) Anchor Protein 11

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
A Kinase (PRKA) Anchor Protein 111 2     Protein Phosphatase 11
AKAP2202 3 5     Regulatory Subunit 441
AKAP 2201 3     PPP1R442
Protein Kinase A Anchoring Protein 111 2     A Kinase Anchor Protein 220 KDa2
Protein Kinase A-Anchoring Protein 112 3     A-Kinase Anchor Protein 112
AKAP-112 3     A-Kinase Anchoring Protein, 220kDa2
PRKA112 3     Protein Phosphatase 1, Regulatory Subunit 442
A-Kinase Anchor Protein 220 KDa2 3     KIAA06293
220kDa1     hAKAP2203
A-Kinase Anchoring Protein1     

External Ids:    HGNC: 3691   Entrez Gene: 112152   Ensembl: ENSG000000235167   OMIM: 6046965   UniProtKB: Q9UKA43   

Export aliases for AKAP11 gene to outside databases

Previous GC identifers: GC13P040846 GC13P036832 GC13P041782 GC13P040644 GC13P041744 GC13P023649


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for AKAP11 Gene:
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function
of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations
within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed at high levels
throughout spermatogenesis and in mature sperm. It binds the RI and RII subunits of PKA in testis. It may serve a
function in cell cycle control of both somatic cells and germ cells in addition to its putative role in
spermatogenesis and sperm function. (provided by RefSeq, Jul 2008)

GeneCards Summary for AKAP11 Gene:
AKAP11 (A kinase (PRKA) anchor protein 11) is a protein-coding gene. GO annotations related to this gene include protein phosphatase 1 binding and protein kinase A binding. An important paralog of this gene is SPHKAP.

UniProtKB/Swiss-Prot: AKA11_HUMAN, Q9UKA4
Function: Binds to type II regulatory subunits of protein kinase A and anchors/targets them

Gene Wiki entry for AKAP11 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000013.10  NT_024524.15  NC_018924.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the AKAP11 gene promoter:
         Max1   RP58   NF-1/L   NF-1   IRF-1   Nkx2-5   HEN1   MRF-2   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidAKAP11 promoter sequence
   Search Chromatin IP Primers for AKAP11

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat AKAP11


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q14.11   Ensembl cytogenetic band:  13q14.11   HGNC cytogenetic band: 13q

AKAP11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AKAP11 gene location

GeneLoc information about chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13P042846:  view genomic region     (about GC identifiers)

Start:
42,846,289 bp from pter      End:
42,897,403 bp from pter
Size:
51,115 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: AKA11_HUMAN, Q9UKA4 (See protein sequence)
Recommended Name: A-kinase anchor protein 11  
Size: 1901 amino acids; 210512 Da
Sequence caution: Sequence=BAA92117.1; Type=Erroneous initiation;
Secondary accessions: O75124 Q9NUK7

Explore the universe of human proteins at neXtProt for AKAP11: NX_Q9UKA4

Explore proteomics data for AKAP11 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys560
  • Modification sites at PhosphoSitePlus

  • See AKAP11 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_057332.1  
    ENSEMBL proteins: 
     ENSP00000025301  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    PPP1R: Serine/threonine phosphatases / Protein phosphatase 1, regulatory subunits
    AKAP: A-kinase anchor proteins

    1 InterPro protein domain:
     IPR008382 SPHK1-interactor_AKAP_110

    Graphical View of Domain Structure for InterPro Entry Q9UKA4

    ProtoNet protein and cluster: Q9UKA4

    1 Blocks protein domain: IPB008382 A-kinase anchor 110 kDa

    UniProtKB/Swiss-Prot: AKA11_HUMAN, Q9UKA4
    Domain: RII-alpha binding site, predicted to form an amphipathic helix, could participate in protein-protein
    interactions with a complementary surface on the R-subunit dimer
    Similarity: Belongs to the AKAP110 family


    Find genes that share domains with AKAP11           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: AKA11_HUMAN, Q9UKA4
    Function: Binds to type II regulatory subunits of protein kinase A and anchors/targets them

         Genatlas biochemistry entry for AKAP11:
    A kinase (PRKA,regulating subunit RIIA) anchor protein 11,expressed in brain,related to rat A kinase anchoring
    protein AKAP220

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008157protein phosphatase 1 binding TAS10209101
    GO:0051018protein kinase A binding TAS10209101
         
    Find genes that share ontologies with AKAP11           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for AKAP11:
     Decreased focal adhesion (FA)   Increased gamma-H2AX phosphory 

         1 MGI phenotypic allele for Akap11 (no phenotypes)

    Find genes that share phenotypes with AKAP11           About GenesLikeMe

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for AKAP11

    miRNA
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    miRTarBase miRNAs that target AKAP11:
    hsa-mir-101-3p (MIRT027289), hsa-mir-615-3p (MIRT040305), hsa-mir-106b-5p (MIRT020469), hsa-mir-148b-3p (MIRT019299), hsa-mir-192-5p (MIRT026113), hsa-mir-186-5p (MIRT021104), hsa-mir-33a-5p (MIRT028239), hsa-mir-122-5p (MIRT023248), hsa-let-7g-5p (MIRT046566), hsa-mir-130b-3p (MIRT020121), hsa-mir-93-5p (MIRT027978), hsa-mir-215-5p (MIRT024763), hsa-mir-23b-3p (MIRT023479), hsa-mir-548b-3p (MIRT016247)

    Block miRNA regulation of human, mouse, rat AKAP11 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate AKAP11 (see all 57):
    hsa-miR-323-3p hsa-miR-142-5p hsa-miR-106a hsa-miR-15a hsa-miR-200a hsa-miR-503 hsa-miR-548l hsa-miR-141
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    AKA11_HUMAN, Q9UKA4: Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
    Note=Cytoplasmic in premeiotic pachytene spermatocytes and in the centrosome of developing postmeiotic germ
    cells, while a midpiece/centrosome localization was found in elongating spermatocytes and mature sperm
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    nucleus4
    plasma membrane4
    cytosol3
    mitochondrion1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus ----
    GO:0005737cytoplasm IEA--
    GO:0005815microtubule organizing center IEA--
    GO:0005886plasma membrane ----

    Find genes that share ontologies with AKAP11           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for AKAP11 About    
    See pathways by source

    SuperPathContained pathways About
    1Activation of cAMP-Dependent PKA
    Activation of cAMP-Dependent PKA0.77
    Activation of PKA through GPCR0.71
    cAMP Pathway0.77
    PKA Signaling0.56
    2G Protein Signaling Pathways
    G Protein Signaling Pathways0.44
    3Signal transduction PKA signaling
    Signal transduction PKA signaling

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    4 Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for AKAP11
        Activation of PKA through GPCR
    PKA Signaling
    cAMP Pathway
    Activation of cAMP-Dependent PKA

    1 GeneGo (Thomson Reuters) Pathway for AKAP11
        Signal transduction PKA signaling

    1 BioSystems Pathway for AKAP11
        G Protein Signaling Pathways


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for AKAP11
    Interactions:

        GeneGlobe Interaction Network for AKAP11

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    Selected Interacting proteins for AKAP11 (Q9UKA43 ENSP000000253014) via UniProtKB, MINT, STRING, and/or I2D (see all 16)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GSK3BP498413, ENSP000003248064I2D: score=3 STRING: ENSP00000324806
    PRKAR1AP106443, ENSP000003514104I2D: score=3 STRING: ENSP00000351410
    PRKAR2AP138613, ENSP000002655634I2D: score=3 STRING: ENSP00000265563
    PRKAR2BP313233, ENSP000002657174I2D: score=3 STRING: ENSP00000265717
    PPP1CAP621363, ENSP000003260314I2D: score=2 STRING: ENSP00000326031
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0035556intracellular signal transduction TAS10209101

    Find genes that share ontologies with AKAP11           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for AKAP11 (AKA11)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for AKAP11 gene (2 alternative transcripts): 
    NM_016248.3  NM_144490.1  

    Unigene Cluster for AKAP11:

    A kinase (PRKA) anchor protein 11
    Hs.105105  [show with all ESTs]
    Unigene Representative Sequence: NM_016248
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000025301(uc001uys.2)
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate AKAP11 (see all 57):
    hsa-miR-323-3p hsa-miR-142-5p hsa-miR-106a hsa-miR-15a hsa-miR-200a hsa-miR-503 hsa-miR-548l hsa-miR-141
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    Additional mRNA sequence: 

    AB014529.2 AF176555.1 AK002166.1 AK074384.1 CR627087.1 

    8 DOTS entries:

    DT.114752  DT.100023768  DT.100704976  DT.100769091  DT.120776864  DT.120776877  DT.95223295  DT.120776881 

    Selected AceView cDNA sequences (see all 156):

    Z45087 BP368267 AI285046 AA862480 AI370183 AA837616 BQ228514 BQ719874 
    NM_016248 AA463313 AA112737 CN479538 AI573202 BP339922 BX483248 AI174605 
    BU620731 AI367927 NM_144490 AI357298 CR627087 CB266408 AI039073 BQ723388 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for AKAP11 (see all 9)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11a · 11b ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16a · 16b ^ 17 ^ 18a · 18b · 18c
    SP1:              -     -                                                                                                                                 
    SP2:                    -                                                                                                                                 
    SP3:                    -     -                                                                                                                           
    SP4:                                                                                                                    -                                 
    SP5:                                                                                                                                                      


    ECgene alternative splicing isoforms for AKAP11

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    AKAP11 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTGAATATAT
    AKAP11 Expression
    About this image

    AKAP11 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    AKAP11 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.105105

    UniProtKB/Swiss-Prot: AKA11_HUMAN, Q9UKA4
    Tissue specificity: Expressed in heart, brain, lung, liver, kidney, testis and ovary. Weakly expressed in skeletal
    muscle, pancreas and spleen

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AKAP11

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for AKAP11 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Akap111 , 5 A kinase (PRKA) anchor protein 111, 5 81.43(n)1
    74.48(a)1
      14 (41.46 cM)5
    2191811  NM_001164503.11  NP_001157975.11 
     784922465 
    chicken
    (Gallus gallus)
    Aves AKAP111 A kinase (PRKA) anchor protein 11 65.78(n)
    55.28(a)
      418835  XM_417031.4  XP_417031.3 
    lizard
    (Anolis carolinensis)
    Reptilia AKAP116
    A kinase (PRKA) anchor protein 11
    42(a)
    1 ↔ 1
    3(70210795-70237975)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.302202 Xenopus laevis transcribed sequence with weak similarity more 80.26(n)    48025371 
    zebrafish
    (Danio rerio)
    Actinopterygii akap111 A kinase (PRKA) anchor protein 11 55.59(n)
    45.85(a)
      558595  XM_005167983.1  XP_005168040.1 


    ENSEMBL Gene Tree for AKAP11 (if available)
    TreeFam Gene Tree for AKAP11 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for AKAP11 gene
    SPHKAP2  
    1 SIMAP similar gene for AKAP11 using alignment to 1 protein entry:     AKA11_HUMAN:
    DKFZp781I12161

    Find genes that share paralogs with AKAP11           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for AKAP11 (see all 1155)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 13 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs95669531,2
    --42844323(+) TTTTTA/TTAAAA 1 -- us2k1 trp30--------
    rs2383531,2
    C,A--42844324(-) TTTTTT/AAAAAA 1 -- us2k1 trp32Minor allele frequency- A:0.00NA 4
    rs1148234911,2
    F--42844328(+) TTAAAA/TAAAAG 1 -- us2k11Minor allele frequency- T:0.01WA 118
    rs1409631311,2
    --42844380(+) CCTTAC/TATTGC 1 -- us2k10--------
    rs598008191,2
    F--42844385(+) TATTGC/TGTTTA 1 -- us2k11Minor allele frequency- T:0.05WA 118
    rs1501882231,2
    --42844491(+) AGCACC/TGCCAT 1 -- us2k10--------
    rs1895454361,2
    --42844492(+) GCACCA/GCCATT 1 -- us2k10--------
    rs788776661,2
    C,F--42844645(+) AAATAT/CGCCTC 1 -- us2k12Minor allele frequency- C:0.04CSA EA 121
    rs95256011,2
    C,F--42844718(+) AGTCTA/GCAATA 1 -- us2k17Minor allele frequency- G:0.11NA WA CSA EA 366
    rs1825732311,2
    --42844947(+) ATCCTC/TACTTA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for AKAP11 (42846289 - 42897403 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for AKAP11:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv832590CNV Gain17160897
    nsv832591CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing AKAP11
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 604696    OMIM disorders: --


    Find genes that share disorders with AKAP11           About GenesLikeMe

    Genetic Association Database (GAD): AKAP11
    Human Genome Epidemiology (HuGE) Navigator: AKAP11 (2 documents)

    Export disorders for AKAP11 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for AKAP11 gene, integrated from 10 sources (see all 37):
    (articles sorted by number of sources associating them with AKAP11)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9734811)1, 2, 3 Ishikawa K.... Ohara O. (DNA Res. 1998)
    2. Localization of a novel human A-kinase-anchoring protein, hAKAP220, during spermatogenesis. (PubMed id 10864471)1, 2, 9 Reinton N.... Tasken K. (Dev. Biol. 2000)
    3. Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies. (PubMed id 19801982)1, 4 Rivadeneira F....Uitterlinden A.G. (Nat. Genet. 2009)
    4. The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)1, 2 Dunham A.... Ross M.T. (Nature 2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (DNA Res. 2002)
    7. Cloning and characterization of a novel A-kinase anchoring protein. AKAP 220, association with testicular peroxisomes. (PubMed id 8621616)1, 3 Lester L.B....Scott J.D. (J. Biol. Chem. 1996)
    8. Multiple interactions within the AKAP220 signaling complex contribute to protein phosphatase 1 regulation. (PubMed id 11152471)1, 9 Schillace R.V....Scott J.D. (J. Biol. Chem. 2001)
    9. Identification and characterization of myeloid translocation gene 16b as a novel a kinase anchoring protein in T lymphocytes. (PubMed id 11823486)1, 9 Schillace R.V.... Carr D.W. (J. Immunol. 2002)
    10. Quantitative study of the interactome of PKCIP involved in the EGF-induced tumor cell chemotaxis. (PubMed id 23402259)1 Chen R....Zhang N. (J. Proteome Res. 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 11215 HGNC: 369 AceView: AKAP11 Ensembl:ENSG00000023516 euGenes: HUgn11215
    ECgene: AKAP11 H-InvDB: AKAP11

    (According to HUGE)
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    HUGE: KIAA0629

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for AKAP11 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for AKAP11 gene:
    Search GeneIP for patents involving AKAP11

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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