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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

AK7 Gene

protein-coding   GIFtS: 55
GCID: GC14P096858

Adenylate Kinase 7

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Adenylate Kinase 71 2
AK 72 3
ATP-AMP Transphosphorylase 72 3
Putative Adenylate Kinase 72
EC 2.7.4.33

External Ids:    HGNC: 200911   Entrez Gene: 1224812   Ensembl: ENSG000001400577   OMIM: 6153645   UniProtKB: Q96M323   

Export aliases for AK7 gene to outside databases

Previous GC identifers: GC14P090675 GC14P094848 GC14P095928 GC14P077043


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for AK7 Gene: 
AK7 (adenylate kinase 7) is a protein-coding gene. Diseases associated with AK7 include reticular dysgenesis, and primary ciliary dyskinesia, and among its related super-pathways are Purine metabolism and superpathway of purine nucleotides de novo biosynthesis I. GO annotations related to this gene include cytidylate kinase activity and adenylate kinase activity.

UniProtKB/Swiss-Prot: KAD7_HUMAN, Q96M32
Function: Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate
group between nucleoside triphosphates and monophosphates. Involved in maintaining ciliary structure and function
(By similarity). Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000014.8  NT_026437.12  NC_018925.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the AK7 gene promoter:
         Oct-B1   GR   oct-B3   oct-B2   FOXD3   HSF1 (long)   FOXL1   HSF1short   GR-alpha   LyF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidAK7 promoter sequence
   Search SABiosciences Chromatin IP Primers for AK7

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AK7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q32.2   Ensembl cytogenetic band:  14q32.2   HGNC cytogenetic band: 14q32.31

AK7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AK7 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14P096858:  view genomic region     (about GC identifiers)

Start:
96,858,448 bp from pter      End:
96,955,764 bp from pter
Size:
97,317 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: KAD7_HUMAN, Q96M32 (See protein sequence)
Recommended Name: Adenylate kinase 7  
Size: 723 amino acids; 82658 Da
Subcellular location: Cytoplasm, cytosol
Secondary accessions: Q8IYP6

Explore the universe of human proteins at neXtProt for AK7: NX_Q96M32

Explore proteomics data for AK7 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96M32

  • AK7 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    AK7 Protein Expression
    REFSEQ proteins: NP_689540.2  
    ENSEMBL proteins: 
     ENSP00000267584   ENSP00000451068   ENSP00000450453  

    Human Recombinant Protein Products for AK7: 
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    GenScript Custom Purified and Recombinant Proteins Services for AK7
    Novus Biologicals AK7 Proteins
    Novus Biologicals AK7 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for AK7 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol IEA--

    AK7 for ontologies           About GeneDecksing



    AK7 Antibody Products: 
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    Cloud-Clone Corp. CLIAs for AK7


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    AK: Adenylate kinases

    5 InterPro protein domains:
     IPR027417 P-loop_NTPase
     IPR000850 Adenylate_kin
     IPR026867 AK7/AK8
     IPR007858 Dpy-30_motif
     IPR016040 NAD(P)-bd_dom

    Graphical View of Domain Structure for InterPro Entry Q96M32

    ProtoNet protein and cluster: Q96M32

    2 Blocks protein domains:
    IPB000850 Adenylate kinase
    IPB007858 Dpy-30


    UniProtKB/Swiss-Prot: KAD7_HUMAN, Q96M32
    Similarity: In the central section; belongs to the adenylate kinase family
    Similarity: In the C-terminal section; belongs to the dpy-30 family


    AK7 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: KAD7_HUMAN, Q96M32
    Function: Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate
    group between nucleoside triphosphates and monophosphates. Involved in maintaining ciliary structure and function
    (By similarity). Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP
    Catalytic activity: ATP + AMP = 2 ADP
    Biophysicochemical properties: Kinetic parameters: KM=1.0 uM for AMP; KM=28 uM for dAMP; KM=1.2 uM for CMP;
    Vmax=1130 pmol/min/ug enzyme with AMP as substrate; Vmax=860 pmol/min/ug enzyme with dAMP as substrate; Vmax=150
    pmol/min/ug enzyme with CMP as substrate;

         Enzyme Number (IUBMB): EC 2.7.4.31

         Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004017adenylate kinase activity IDA--
    GO:0004127cytidylate kinase activity IDA--
    GO:0004550nucleoside diphosphate kinase activity IDA--
    GO:0005524ATP binding IEA--
    GO:0019205nucleobase-containing compound kinase activity ----
         
    AK7 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for AK7:
     Decreased viability with pacli 

         6 MGI mutant phenotypes (inferred from 1 allele(MGI details for Ak7):
     craniofacial  growth/size  mortality/aging  nervous system  reproductive system 
     respiratory system 

    AK7 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for AK7 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for AK7

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for AK7 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for AK7 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat AK7
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate AK7:
    hsa-miR-3671 hsa-miR-607 hsa-miR-29a*
    SwitchGear 3'UTR luciferase reporter plasmidAK7 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Gene Editing
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    Clone
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    GenScript: all cDNA clones in your preferred vector (see all 2): AK7 (NM_020341)
    Browse Sino Biological Human cDNA Clones
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AK7


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for AK7 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Purine metabolism
    Purine metabolism0.38
    ATP/ITP metabolism0.31
    2adenosine ribonucleotides de novo biosynthesis
    adenosine ribonucleotides de novo biosynthesis0.49
    superpathway of purine nucleotides de novo biosynthesis I0.49
    3Metabolism
    Metabolic pathways0.40
    4Neuropathic Pain-Signaling in Dorsal Horn Neurons
    Cholera Infection0.40
    5AMPK Enzyme Complex Pathway
    AMPK Enzyme Complex Pathway

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 EMD Millipore Pathway for AK7
        ATP/ITP metabolism

    2 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for AK7
        Cholera Infection
    AMPK Enzyme Complex Pathway

    1 GeneGo (Thomson Reuters) Pathway for AK7
        ATP/ITP metabolism

    2 BioSystems Pathways for AK7
        superpathway of purine nucleotides de novo biosynthesis I
    adenosine ribonucleotides de novo biosynthesis


    2         Kegg Pathways  (Kegg details for AK7):
        Purine metabolism
    Metabolic pathways


    AK7 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for AK7

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/48 Interacting proteins for AK7 (ENSP000002675844) via UniProtKB, MINT, STRING, and/or I2D (see all 48)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NME5ENSP000002651914STRING: ENSP00000265191
    NME7ENSP000003567854STRING: ENSP00000356785
    ADKENSP000002866214STRING: ENSP00000286621
    ADSLENSP000002161944STRING: ENSP00000216194
    AMPD1ENSP000003165204STRING: ENSP00000316520
    About this table

    Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0002437inflammatory response to antigenic stimulus IEA--
    GO:0003351epithelial cilium movement IEA--
    GO:0006139nucleobase-containing compound metabolic process ----
    GO:0006165nucleoside diphosphate phosphorylation IDA--
    GO:0007283spermatogenesis IEA--

    AK7 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for AK7 (KAD7)

    5 HMDB Compounds for AK7    About this table
    CompoundSynonyms CAS #PubMed Ids
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    Adenosine monophosphate5'-AMP (see all 28)61-19-8--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    Deoxyadenosine monophosphate2'-Deoxy-5'-adenylate (see all 24)653-63-4--
    dADP2'-deoxyadenosine-5'-diphosphate (see all 3)2793-06-8--

    Search CenterWatch for drugs/clinical trials and news about AK7 / KAD7

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for AK7 gene: 
    NM_152327.3  

    Unigene Cluster for AK7:

    Adenylate kinase 7
    Hs.667462  [show with all ESTs]
    Unigene Representative Sequence: NM_152327
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000267584(uc001yfn.2) ENST00000555570(uc001yfm.1) ENST00000556643
    ENST00000554313 ENST00000554706
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat AK7
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate AK7:
    hsa-miR-3671 hsa-miR-607 hsa-miR-29a*
    SwitchGear 3'UTR luciferase reporter plasmidAK7 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for AK7
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat AK7
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    OriGene ORF clones in mouse, rat for AK7
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): AK7 (NM_020341)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for AK7
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AK7
    Sirion Biotech Customized lentivirus for stable overexpression of AK7 
                         Customized lentivirus expression plasmids for stable overexpression of AK7 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for AK7
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat AK7
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat AK7
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AK7

    Additional mRNA sequence: 

    AK057426.1 BC023986.1 BC035256.1 

    5 DOTS entries:

    DT.100014700  DT.75137763  DT.75100746  DT.65285585  DT.100018557 

    24/36 AceView cDNA sequences (see all 36):

    BU607380 CA313867 BU622508 BM981526 CA312368 AI792423 AI792424 BU675343 
    BU944613 BC035256 BG762190 AI739250 AI761827 BM982686 BX489283 BX097430 
    BM018498 AI733700 AI191504 NM_152327 CA416623 AK057426 AI733701 BU684495 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    AK7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACTTGTTATC
    AK7 Expression
    About this image


    See AK7 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for AK7

    SOURCE GeneReport for Unigene cluster: Hs.667462
        SABiosciences Custom PCR Arrays for AK7
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AK7

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for AK7 gene from 5/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ak71 , 5 adenylate kinase 71, 5 82.5(n)1
    85.69(a)1
      12 (55.95 cM)5
    788011  NM_030187.11  NP_084463.11 
     1057059825 
    chicken
    (Gallus gallus)
    Aves AK71 adenylate kinase 7 70.37(n)
    68.23(a)
      428907  XM_426462.3  XP_426462.2 
    lizard
    (Anolis carolinensis)
    Reptilia AK76
    Uncharacterized protein
    66(a)
    1 ↔ 1
    1(7851753-7890386)
    African clawed frog
    (Xenopus laevis)
    Amphibia ak7-A-prov2 adenylate kinase 7 74.77(n)    BC049290.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.283792 Danio rerio cDNA clone IMAGE6795258, partial cds 73.67(n)    BC056555.1 


    ENSEMBL Gene Tree for AK7 (if available)
    TreeFam Gene Tree for AK7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for AK7 gene
    1 SIMAP similar gene for AK7 using alignment to 3 protein entries:     KAD7_HUMAN (see all proteins):
    DPY30

    AK7 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2047 SNPs in AK7 are shown (see all 2047)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs101303351,2
    C,F,H--96856579(+) TTTGGA/CGACCA 1 -- us2k1 tfbs330Minor allele frequency- C:0.18NS EA NA WA CSA 2675
    rs1145662671,2
    C,F--96856643(+) TGGTGG/TTATCA 1 -- us2k11Minor allele frequency- T:0.02WA 118
    rs1902032411,2
    --96856794(+) TGTTGC/GGCCAC 1 -- us2k10--------
    rs1831327181,2
    --96856867(+) CCTGTA/GAATCA 1 -- us2k10--------
    rs1877721701,2
    --96856895(+) GAGGCA/GGGTGG 1 -- us2k10--------
    rs1504307161,2
    C--96856981(+) TAGCCA/GGGAAC 1 -- us2k10--------
    rs1383590121,2
    C--96856986(+) GGGAAC/TGGTGG 1 -- us2k10--------
    rs1438660381,2
    --96857020(+) TTCGAA/GGGCTG 1 -- us2k10--------
    rs1472391471,2
    --96857025(+) AGGCTA/GAGGCA 1 -- us2k10--------
    rs1494281461,2
    C--96857109(+) CAGAGA/CGAGAC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for AK7 (96858448 - 96955764 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for AK7:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2674373CNV Deletion23128226
    nsv510389CNV Loss20534489
    nsv902211CNV Loss21882294

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing AK7
    DNA2.0 Custom Variant and Variant Library Synthesis for AK7

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 615364    OMIM disorders: --

    4 diseases for AK7:    About MalaCards
    reticular dysgenesis    primary ciliary dyskinesia    bronchiectasis    cholera

    2 diseases from the University of Copenhagen DISEASES database for AK7:
    Primary ciliary dyskinesia     Reticular dysgenesis

    AK7 for disorders           About GeneDecksing

    Genetic Association Database (GAD): AK7
    Human Genome Epidemiology (HuGE) Navigator: AK7 (2 documents)

    Export disorders for AK7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for AK7 gene, integrated from 9 sources (see all 11):
    (articles sorted by number of sources associating them with AK7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    2. The characterization of human adenylate kinases 7 and 8 demonstrates differences in kinetic parameters and structural organization a mong the family of adenylate kinase isoenzymes. (PubMed id 21080915)1, 2 Panayiotou C....Karlsson A. (2010)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. The DNA sequence and analysis of human chromosome 14. (PubMed id 12508121)1, 2 Heilig R.... Weissenbach J. (2003)
    5. New adenylate kinase 7 (AK7) mutation in primary cilia ry dyskinesia. (PubMed id 22801010)1 Mata M....Cortijo J. (2012)
    6. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    7. Single-nucleotide polymorphisms, acute rejection, and severity of tubulitis in kidney transplantation, accounting for center-to-center variation. (PubMed id 21085059)4 Israni A....Oetting W.S. (2010)
    8. Role of adenylate kinase type 7 expression on cilia m otility: possible link in primary ciliary dyskinesia. (PubMed id 20537283)1 Milara J....Cortijo J. (2010)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1 Gerhard D.S....Malek J. (2004)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 122481 HGNC: 20091 AceView: AK7 Ensembl:ENSG00000140057 euGenes: HUgn122481
    ECgene: AK7 Kegg: 122481 H-InvDB: AK7

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for AK7 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for AK7 gene:
    Search GeneIP for patents involving AK7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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