Aliases for AK7 Gene
External Ids for AK7 Gene
Previous GeneCards Identifiers for AK7 Gene
This gene encodes a member of the adenylate kinase family of enzymes. The encoded enzyme is a phosphotransferase that catalyzes the reversible phosphorylation of adenine nucleotides. This enzyme plays a role in energy homeostasis of the cell. Alternative splicing results in multiple transcript variants. Mutations in the mouse gene are associated with primary ciliary dyskinesia. [provided by RefSeq, Apr 2017]
GeneCards Summary for AK7 Gene
AK7 (Adenylate Kinase 7) is a Protein Coding gene. Diseases associated with AK7 include Reticular Dysgenesis and Primary Ciliary Dyskinesia. Among its related pathways are Metabolism and Purine metabolism. GO annotations related to this gene include nucleoside diphosphate kinase activity and nucleobase-containing compound kinase activity.
UniProtKB/Swiss-Prot for AK7 Gene
Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity. Involved in maintaining ciliary structure and function.