AJUBA Gene
protein-coding GIFtS: 48
GCID: GC14M023441
|
|
ajuba LIM protein(Previous names: jub, ajuba homolog (Xenopus laevis) )
(Previous symbol: JUB)
| |
Aliases
for AJUBA gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ajuba LIM Protein1 2 | | Jub, Ajuba Homolog2 | | JUB1 2 3 | | LIM Domain-Containing Protein Ajuba2 | | MGC155631 | | Protein Ajuba2 | | Jub, Ajuba Homolog (Xenopus Laevis)1 | | |
Export aliases for AJUBA gene to outside databases |
Summaries
for AJUBA gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: AJUBA_HUMAN, Q96IF1Function: Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involvedin several cellular processes such as cell fate determination, cytoskeletal organization, repression of genetranscription, mitosis, cell-cell adhesion, cell differentiation, proliferation and migration. Contributes to thelinking and/or strengthening of epithelia cell-cell junctions in part by linking adhesive receptors to the actincytoskeleton. May be involved in signal transduction from cell adhesion sites to the nucleus. Plays an important rolein regulation of the kinase activity of AURKA for mitotic commitment. Also a component of the IL-1 signaling pathwaymodulating IL-1-induced NFKB1 activation by influencing the assembly and activity of the PRKCZ-SQSTM1-TRAF6multiprotein signaling complex. Functions as an HDAC-dependent corepressor for a subset of GFI1 target genes. Acts asa transcriptional corepressor for SNAI1 and SNAI2/SLUG-dependent repression of E-cadherin transcription. Acts as ahypoxic regulator by bridging an association between the prolyl hydroxylases and VHL enabling efficient degradation ofHIF1A. Positively regulates microRNA (miRNA)-mediated gene silencing. Negatively regulates the Hippo signaling pathwayand antagonizes phosphorylation of YAP1
Gene Wiki entry for AJUBA (JUB)
|
Genomic Views
for AJUBA gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000014.8 NC_018925.1 NT_026437.12
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for AJUBA
Other transcription factors
Search SABiosciences Chromatin IP Primers for AJUBA
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AJUBA |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 14q11.2 Ensembl cytogenetic band: 14q11.2 HGNC cytogenetic band: 14q11.2AJUBA Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 14 GeneLoc Exon Structure GeneLoc location for GC14M023441: view genomic region
(about GC identifiers)
Start:
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23,440,383 bp from pter |
End:
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23,451,851 bp from pter |
Size:
|
11,469 bases |
Orientation:
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minus strand |
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Proteins
for AJUBA gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: AJUBA_HUMAN, Q96IF1 (See
protein sequence)Recommended Name: LIM domain-containing protein ajuba Size: 538 amino acids; 56934 Da
Subunit: Interacts with GRB2, PIP5K1B and SLC1A2 (By similarity). Interacts with AURKA; the interaction occurs duringmitosis and both proteins are phosphorylated as they form a complex. Interacts with CTNNA1 and with F-actin. Interactswith LATS2; the interaction occurs during mitosis and the complex regulates organization of the spindle apparatusthrough recruitment of TUBG to the centrosome. Forms a complex with SQSTM1, PRKCZ and TRAF6. Component of theGFI1-AJUBA-HDAC1 repressor complex. Interacts directly (via the LIM domains) with GFI1; the interaction results in theHDAC-dependent corepression of a subset of GFI1 target genes, and is independent of the GFI1 SNAG domain. Interactswith HDAC1, HDAC2 and HDAC3. Interacts with SNAI2/SLUG (via SNAG domain) and SCRT1 (via SNAG domain) (By similarity).Interacts with EIF4E, EIF2C1, EIF2C2, DCP2, DDX6, LATS1, LATS2, SAV1, EGLN2/PHD1 and EGLN3/PHD3. Interacts (via LIMdomains) with isoform 1 and isoform 3 of VHL. Interacts (via LIM domains) with SNAI1 (via SNAG domain)
Subcellular location: Cytoplasm, cytoskeleton. Cell membrane. Cell junction. Nucleus. Cytoplasm, cytoskeleton,centrosome. Cytoplasm, P-body. Note=Shuttles between the cytoplasm and the nucleus. Localizes on centrosomes duringG2-M phase. Preferentially co-localizes with cadherin-adhesive complexes at sites of cell-cell contacts. Colocalizeswith GFI1 in the nucleus
Miscellaneous: 'Ajuba' means 'curiosity' in Urdu, an Indian dialect
Secondary accessions: A8MX18 D3DS37Alternative splicing: 2 isoforms: Q96IF1-1 Q96IF1-2 Explore the universe of human proteins at neXtProt for AJUBA: NX_Q96IF1
Post-translational modifications:
Phosphorylated by LATS2 during mitosis. Phosphorylated by AURKA1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96IF1
AJUBA Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_116265.1 NP_932352.1
ENSEMBL proteins: ENSP00000262713 ENSP00000380543 ENSP00000452369 ENSP00000451649 ENSP00000452325 ENSP00000451772 ENSP00000354491
Human Recombinant Protein Products for AJUBA:
Gene Ontology (GO): 5/9 cellular component terms (GO ID links to tree view) (see all 9): About this table
AJUBA for ontologies About GeneDecksing
AJUBA Antibody Products:
Assay Products for AJUBA: |
Protein
Domains /
Families
for AJUBA gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
AJUBA for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q96IF1ProtoNet protein and cluster: Q96IF1 1 Blocks protein family: IPB001781 Zn-binding protein
UniProtKB/Swiss-Prot: AJUBA_HUMAN, Q96IF1Domain: LIM region interacts with CTNNA1. The preLIM region binds directly actin filamentsDomain: LIM-2 and LIM-3 domains mediate the interaction with the N-terminal region of AURKA. The association betweenLATS2 and AJUBA required the second LIM domain of AJUBASimilarity: Belongs to the zyxin/ajuba familySimilarity: Contains 3 LIM zinc-binding domains |
Function
for AJUBA gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: AJUBA_HUMAN, Q96IF1Function: Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involvedin several cellular processes such as cell fate determination, cytoskeletal organization, repression of genetranscription, mitosis, cell-cell adhesion, cell differentiation, proliferation and migration. Contributes to thelinking and/or strengthening of epithelia cell-cell junctions in part by linking adhesive receptors to the actincytoskeleton. May be involved in signal transduction from cell adhesion sites to the nucleus. Plays an important rolein regulation of the kinase activity of AURKA for mitotic commitment. Also a component of the IL-1 signaling pathwaymodulating IL-1-induced NFKB1 activation by influencing the assembly and activity of the PRKCZ-SQSTM1-TRAF6multiprotein signaling complex. Functions as an HDAC-dependent corepressor for a subset of GFI1 target genes. Acts asa transcriptional corepressor for SNAI1 and SNAI2/SLUG-dependent repression of E-cadherin transcription. Acts as ahypoxic regulator by bridging an association between the prolyl hydroxylases and VHL enabling efficient degradation ofHIF1A. Positively regulates microRNA (miRNA)-mediated gene silencing. Negatively regulates the Hippo signaling pathwayand antagonizes phosphorylation of YAP1 Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6): About this table
AJUBA for ontologies About GeneDecksing
Phenotypes:
1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Ajuba):
AJUBA for phenotypes About GeneDecksing
Animal Models:
Mouse knock-out Ajubatm1Gdl for AJUBA
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for AJUBA (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for AJUBA (see all 2)
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Synthesis Service for AJUBA | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AJUBA |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AJUBA |
|
Pathways & Interactions
for AJUBA gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Cytoskeletal Signaling | | | 2 | Adhesion | | | 3 | Aurora A signaling | | | 4 | E-cadherin signaling in keratinocytes | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Cell Signaling Technology (CST) Pathways for AJUBA
2  BioSystems Pathways for AJUBA
AJUBA for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for AJUBA
STRING Interaction
Network Preview (showing 5 interactants - click image to see 20)
5/25 Interacting proteins for AJUBA (Q96IF12, 3 ENSP000002627134) via UniProtKB, MINT, STRING, and/or I2D (see all 25)About this table
Gene Ontology (GO): 5/22 biological process terms (GO ID links to tree view) (see all 22): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000122 | negative regulation of transcription from RNA polymerase II promoter |
IEA | -- | | GO:0001666 | response to hypoxia |
IDA | -- | | GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0007049 | cell cycle |
IEA | -- | | GO:0016339 | calcium-dependent cell-cell adhesion |
IEA | -- |
AJUBA for ontologies About GeneDecksing
|
Drugs & Compounds
for AJUBA gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for AJUBA
Search CenterWatch for drugs/clinical trials and news about AJUBA
|
Transcripts
for AJUBA gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for AJUBA gene (2 alternative transcripts): NM_032876.4 NM_198086.1 Unigene Cluster for AJUBA: Ajuba LIM protein Hs.655832 [show with all ESTs]Unigene Representative Sequence: NM_0328768 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000262713(uc001why.3 uc001whz.3) ENST00000397388 ENST00000553592
ENST00000556731 ENST00000553911 ENST00000555479 ENST00000553736 ENST00000361265
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for AJUBA (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for AJUBA (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for AJUBA | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for AJUBA | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AJUBA |
Additional cDNA sequence: AK025567.1 AK096128.1 AY169959.1 BC007580.1 BC016733.1 BC034968.2 10 DOTS entries: DT.100775739 DT.455766 DT.120777830 DT.92426492 DT.102836338 DT.100775734 DT.100737442 DT.40129291 DT.120777678 DT.100775735 24/146 AceView cDNA sequences (see all 146): BU163376 BM718100 BQ439546 BI260853 BC007580 BU543883 CA442366 BU149830 BQ232031 NM_032876 CB135297 D12422 BM680549 CN482905 AY169959 AI918246 BQ958701 BM479543 NM_198086 BI333383 CB106008 BC016733 AK096128 BM756795
GeneLoc Exon Structure
|
Expression
for AJUBA gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| AJUBA expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTTTGGATAT
About this image
See AJUBA Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for AJUBA
SOURCE GeneReport for Unigene cluster: Hs.655832
SABiosciences Custom PCR Arrays for AJUBA
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for AJUBA
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat AJUBA | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat AJUBA | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AJUBA | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AJUBA |
Orthologs
for AJUBA gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for AJUBA gene from 3/15 species (see all 15) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
zebrafish
(Danio rerio) |
Actinopterygii |
ajuba1 |
ajuba LIM protein |
56.34(n)
53.85(a) |
|
572549 XM_696274.5 XP_701366.4 |
fruit fly
(Drosophila melanogaster) |
Insecta |
jub6 |
Ajuba LIM protein |
20(a) |
1 → many |
X(13720363-13724347) |
worm
(Caenorhabditis elegans) |
Secernentea |
zyx-16 |
ZYXin family member (zyx-1) |
14(a) |
1 → many |
II(13056744-13071460) |
ENSEMBL Gene Tree for AJUBA (if available)
TreeFam Gene Tree for AJUBA (if available) |
Paralogs
for AJUBA gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for AJUBA gene
- LPP2 FBLIM12 TRIP62 WTIP2 ZYX2 LIMD12
11 SIMAP similar genes for AJUBA using alignment to 4 protein entries: AJUBA_HUMAN (see all proteins):WTIP CSRP1 DKFZp686P2249 LIMD1 FHL2 LIMS2
ABLIM1 PDLIM5 LDB3 ABLIM2 ISL2
AJUBA for paralogs About GeneDecksing
|
Genomic Variants
for AJUBA gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 14 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for AJUBA (23440383 - 23451851 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for AJUBA: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing AJUBA |
|
Disorders
/ Diseases
for AJUBA gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
AJUBA for disorders About GeneDecksing
OMIM gene information: 609066
OMIM disorders: --
5  diseases for AJUBA: About MalaCardsintrahepatic cholangiocarcinoma cholangiocarcinoma breast cancer ataxia
hypoxia
Export disorders for AJUBA gene to outside databases
|
Publications
for AJUBA gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for AJUBA gene, integrated from 9 sources (see all 34):
(articles sorted by number of sources associating them with AJUBA) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity. (PubMed id 22286099)1, 2 Foxler D.E.... Sharp T.V. (2012)
- Ajuba LIM proteins are snail/slug corepressors required for neural crest development in Xenopus. (PubMed id 18331720)1, 2 Langer E.M....Longmore G.D. (2008)
- Ajuba functions as a histone deacetylase-dependent co-repressor for autoregulation of the growth factor-independent-1 transcription factor. (PubMed id 18805794)1, 2 Montoya-Durango D.E....Grimes H.L. (2008)
- LATS2-Ajuba complex regulates gamma-tubulin recruitment to centrosomes and spindle organization during mitosis. (PubMed id 16413547)1, 2 Abe Y.... Yamamoto T. (2006)
- The LIM protein Ajuba influences interleukin-1-induced NF-kappaB activation by affecting the assembly and activity of the protein kinase Czeta/p62/TRAF6 signaling complex. (PubMed id 15870274)1, 2 Feng Y. and Longmore G.D. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The LIM protein Ajuba is recruited to cadherin-dependent cell junctions through an association with alpha-catenin. (PubMed id 12417594)1, 2 Marie H.... Braga V.M. (2003)
- Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells. (PubMed id 13678582)1, 2 Hirota T.... Saya H. (2003)
- Ajuba, a novel LIM protein, interacts with Grb2, augments mitogen-activated protein kinase activity in fibroblasts, and promotes meiotic maturation of Xenopus oocytes in a Grb2- and Ras-dependent manner. (PubMed id 10330178)1, 3 Goyal R.K....Longmore G.D. (1999)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
|
External Searches for AJUBA gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing AJUBA gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing AJUBA gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing AJUBA gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for AJUBA | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for AJUBA gene:
Search GeneIP for patents involving AJUBA
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for AJUBA gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for AJUBA | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for AJUBA | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for AJUBA | | | OriGene Protein Over-expression Lysate for AJUBA | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for AJUBA | | OriGene 3'-UTR Clone for AJUBA | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for AJUBA | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for AJUBA | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for AJUBA | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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