|
|
antisense of IGF2R non-protein coding RNA(Previous name: antisense of IGF2R RNA (non-protein coding) )
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Aliases
for AIRN gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
Subcategory (RNA class): non-coding RNA
Quality score for this RNA gene is 2
| Aliases |
|---|
| Antisense Of IGF2R Non-Protein Coding RNA1 2 | | NCRNA000881 2 | | AIR1 2 5 | | Antisense Of IGF2R RNA (Non-Protein Coding)1 | | IGF2R-AS11 2 | | IGF2R-AS2 | | IGF2RAS1 2 | | |
Export aliases for AIRN gene to outside databasesPrevious GC identifer: GC00U922835 |
Summaries
for AIRN gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for AIRN:
Both spliced and un-spliced long non-coding RNAs are transcribed from this gene. This gene overlaps on the oppositestrand the second intron of the insulin-like growth factor 2 receptor gene; a CpG island associated with the secondintron denotes an active promoter that drives the expression of this gene. The related mouse gene is responsible forsilencing the insulin-like growth factor 2 receptor gene and flanking genes in the imprinted gene cluster of mice.This gene may be expressed in Wilms tumors. (provided by RefSeq, Feb 2013)
|
Genomic Views
for AIRN gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_025741.15
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for AIRN
Other transcription factors
Search SABiosciences Chromatin IP Primers for AIRN
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AIRN |
Genomic Location:
Chromosome:6
Entrez Gene cytogenetic band: 6q26 HGNC cytogenetic band: 6q26GeneLoc information about chromosome 6 |
Proteins
for AIRN gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB: --
|
Protein
Domains /
Families
for AIRN gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| -- |
Function
for AIRN gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Animal Models:
Mouse knock-out Airntm1Dpb for AIRN
4 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Airn):
AIRN for phenotypes About GeneDecksing
|
Pathways & Interactions
for AIRN gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for AIRN
|
Drugs & Compounds
for AIRN gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for AIRN
Search CenterWatch for drugs/clinical trials and news about AIRN 
|
Transcripts
for AIRN gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
Unigene Cluster for AIRN: Antisense of IGF2R non-protein coding RNA Hs.742166 [show with all ESTs]Unigene Representative Sequence: NR_047514
Additional cDNA sequence: GQ166646.1 NR_047511.1 NR_047514.1 1 DOTS entry: DT.91754395
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Expression
for AIRN gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| Expression evidence for AIRN:none
See probesets specificity/sensitivity at GeneAnnot
CGAP TAG: --
SOURCE GeneReport for Unigene cluster: Hs.742166
SABiosciences Custom PCR Arrays for AIRN
Primer
Products: |  | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat AIRN | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat AIRN | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AIRN |
Orthologs
for AIRN gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of human and mouse.
Orthologs for AIRN gene from 1 species (see representative species ) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Airn5 |
antisense Igf2r RNA |
-- |
|
17 (8.66 cM) 12741311 |
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Paralogs
for AIRN gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for AIRN gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
| | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for AIRN gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
AIRN for disorders About GeneDecksing
OMIM gene information: 604893
OMIM disorders: --
1  disease for AIRN: About MalaCardswilms tumor
Export disorders for AIRN gene to outside databases
|
Publications
for AIRN gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for AIRN gene integrated from 9 sources:
(articles sorted by number of sources associating them with AIRN) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification of the human homolog of the imprinted mouse Air non-coding RNA. (PubMed id 18789384)1, 3 Yotova I.Y....Barlow D.P. (2008)
- Silencing and transcriptional properties of the imprinted Airn ncRNA are independent of the endogenous promoter. (PubMed id 19008856)1, 3 Stricker S.H....Barlow D.P. (2008)
- A downstream CpG island controls transcript initiation and elongation and the methylation state of the imprinted Airn macro ncRNA prom oter. (PubMed id 22396659)1 Koerner M.V....Barlow D.P. (2012)
- Long non-coding RNA modifies chromatin: epigenetic sil encing by long non-coding RNAs. (PubMed id 21915889)1 Saxena A. and Carninci P. (2011)
- Kcnq1ot1: a chromatin regulatory RNA. (PubMed id 21345374)1 Kanduri C. (2011)
- Creation of genome-wide protein expression libraries using random activation of gene expression. (PubMed id 11329013)1 Harrington J.J.... Ducar M. (2001)
|
External Searches for AIRN gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing AIRN gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing AIRN gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing AIRN gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for AIRN | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for AIRN gene:
Search GeneIP for patents involving AIRN
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for AIRN gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat AIRN | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing AIRN | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AIRN | | | Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat AIRN | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AIRN | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat AIRN |
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| | | | Search Tocris compounds for AIRN |
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 | | | | |  |  |  | | | | Search ThermoFisher Antibodies for AIRN |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat AIRN |
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