AIP Gene
protein-coding GIFtS: 59
GCID: GC11P067251
|
|
aryl hydrocarbon receptor interacting protein(Previous name: aryl hydrocarbon receptor-interacting protein )
| |
Aliases
for AIP gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Aryl Hydrocarbon Receptor Interacting Protein1 2 | | HBV X-Associated Protein 22 3 | | XAP21 2 3 5 | | Aryl Hydrocarbon Receptor-Interacting Protein1 | | ARA91 2 5 | | FKBP372 | | FKBP161 2 | | SMTPHN2 | | Immunophilin Homolog ARA92 3 | | AH Receptor-Interacting Protein2 | | XAP-22 3 | | Aryl-Hydrocarbon Receptor-Interacting Protein3 |
Export aliases for AIP gene to outside databasesPrevious GC identifers: GC11P069773 GC11P068946 GC11P067500 GC11P067026 GC11P067027 GC11P067007 GC11P063579 |
Summaries
for AIP gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for AIP:
The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. Theencoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transportedto the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encodedprotein can bind specifically to and inhibit the activity of hepatitis B virus. (provided by RefSeq, Sep 2008)
UniProtKB/Swiss-Prot: AIP_HUMAN, O00170Function: May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencingits receptivity for ligand and/or its nuclear targetingFunction: Cellular negative regulator of the hepatitis B virus (HBV) X protein
Gene Wiki entry for AIP (AH receptor-interacting protein)
|
Genomic Views
for AIP gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_167190.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the AIP gene promoter:
PPAR-alpha AhR FAC1 PPAR-gamma1 Pax-5 PPAR-gamma2 Pax-4a GATA-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for AIP
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AIP |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q13.3 Ensembl cytogenetic band: 11q13.2 HGNC cytogenetic band: 11q13.3AIP Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11P067251: view genomic region
(about GC identifiers)
Start:
|
67,250,505 bp from pter |
End:
|
67,258,579 bp from pter |
Size:
|
8,075 bases |
Orientation:
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plus strand |
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Proteins
for AIP gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: AIP_HUMAN, O00170 (See
protein sequence)Recommended Name: AH receptor-interacting protein Size: 330 amino acids; 37636 Da
Subunit: Interacts with RET in the pituitary gland; this interaction prevents the formation of the AIP-survivin complex
Subcellular location: Cytoplasm
3 PDB 3D structures from  and Proteopedia  for AIP:2LKN (3D)
4AIF (3D)
4APO (3D)
Secondary accessions: A0SZW3 A0SZW4 A0SZW5 A0SZW6 Q2M3Q2 Q99606Explore the universe of human proteins at neXtProt for AIP: NX_O00170
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O00170
AIP Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_003968.2
ENSEMBL proteins: ENSP00000434982 ENSP00000279146 ENSP00000434580
Human Recombinant Protein Products for AIP:
Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7): About this table
AIP for ontologies About GeneDecksing
AIP Antibody Products:
Assay Products for AIP: |
Protein
Domains /
Families
for AIP gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
AIP for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O00170ProtoNet protein and cluster: O00170 UniProtKB/Swiss-Prot: AIP_HUMAN, O00170Similarity: Contains 1 PPIase FKBP-type domainSimilarity: Contains 2 TPR repeats |
Function
for AIP gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: AIP_HUMAN, O00170Function: May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencingits receptivity for ligand and/or its nuclear targetingFunction: Cellular negative regulator of the hepatitis B virus (HBV) X protein Genatlas biochemistry entry for AIP:arylhydrocarbon receptor associated protein,immunophilin homolog,interacting with HSP90-AHR complex,homologous to the52kDa,FK506 binding protein (FKBP52)
Gene Ontology (GO): 5/8 molecular function terms (GO ID links to tree view) (see all 8): About this table
AIP for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for AIP:
9 MGI mutant phenotypes (inferred from 4 alleles ) (MGI details for Aip):
AIP for phenotypes About GeneDecksing
Animal Models:
Mouse knock-out Aiptm1Bra for AIP
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for AIP (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for AIP
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): AIP (NM_004536) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for AIP | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AIP |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AIP |
|
Pathways & Interactions
for AIP gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | AHR Pathway | |
1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for AIP
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for AIP
STRING Interaction
Network Preview (showing 5 interactants - click image to see 19)
5/26 Interacting proteins for AIP (O001701, 2, 3 ENSP000002791464) via UniProtKB, MINT, STRING, and/or I2D (see all 26)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| IRF7 | Q929851, 3, ENSP000003294114 | EBI-704197,EBI-2339383 I2D:
score=1 STRING: ENSP00000329411 | | HSP90AB1 | P082382, 3, ENSP000003258754 | MINT-7021862 I2D:
score=1 STRING: ENSP00000325875 | | PDE2A | O004081, 3, ENSP000003349104 | EBI-704197,EBI-1785967 I2D:
score=1 STRING: ENSP00000334910 | | TNNI3K | Q59H183, ENSP000003599284 | I2D:
score=3 STRING: ENSP00000359928 | | AHR | P358693, ENSP000002420574 | I2D:
score=8 STRING: ENSP00000242057 |
About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table
AIP for ontologies About GeneDecksing
|
Drugs & Compounds
for AIP gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for AIP
Search CenterWatch for drugs/clinical trials and news about AIP
|
Transcripts
for AIP gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for AIP gene: NM_003977.2 Unigene Cluster for AIP: Aryl hydrocarbon receptor interacting protein Hs.412433 [show with all ESTs]Unigene Representative Sequence: BG9130064 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000528641 ENST00000279146(uc001olv.3) ENST00000529797 ENST00000525341
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for AIP (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for AIP
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): AIP (NM_004536) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for AIP | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AIP |
Additional cDNA sequence: BC104797.1 BC104827.1 U31913.1 U78521.1 12 DOTS entries: DT.75147837 DT.100796850 DT.100796855 DT.100796857 DT.120759409 DT.91757342 DT.95371818 DT.95371806 DT.91757336 DT.95279473 DT.95342429 DT.95371808 24/451 AceView cDNA sequences (see all 451): BE795399 CR601003 AL582989 BQ108633 CR604495 BF343441 AL134984 BQ054206 AU186128 CR620315 CR607044 BI820432 BQ674196 BU846005 BQ049450 BG024960 CA455131 BE745947 BQ637349 BM767342 BE559496 BQ927863 BG575351 BM747967
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for AIP About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6 | ^ | 7 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | - | | | | | | |
| SP2: | | | | | - | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | - | | | | | | - | | | | | | | | | | | | |
| SP5: | | | | | - | | - | | - | | - | | | | | | | | | | | |
ECgene alternative splicing isoforms for AIP
|
Expression
for AIP gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| AIP expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See AIP Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for AIP
SOURCE GeneReport for Unigene cluster: Hs.412433
UniProtKB/Swiss-Prot: AIP_HUMAN, O00170Tissue specificity: Widely expressed. Higher levels seen in the heart, placenta and skeletal muscle. Not expressed inthe liver
SABiosciences Expression via Pathway-Focused PCR Array including AIP:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for AIP
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat AIP | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat AIP | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AIP | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AIP |
Orthologs
for AIP gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for AIP gene from 6/22 species (see all 22) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
AIP1 |
aryl hydrocarbon receptor interacting protein |
80.08(n)
80.19(a) |
|
395123 NM_204469.1 NP_989800.1 |
lizard
(Anolis carolinensis) |
Reptilia |
AIP6 |
-- |
81(a) |
1 ↔ 1 |
1(94169432-94177527) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.80542 |
Xenopus laevis transcribed sequence with weak similarity more |
74.97(n) |
|
BX848099.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
AF274877.12 |
-- |
79.15(n) |
|
AF274877.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG18471 , 3 |
aryl hydrocarbon-receptor binding3
CG18471 |
39(a)3
51.89(n)1
40.13(a)1 |
|
10F23
321441 NM_132530.31 NP_572758.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
C56C10.101 , 3 |
TPR domain3
Protein C56C10.101 |
34(a)3
44.62(n)1
36.39(a)1 |
|
II(6592533-6594197)3
1740921 NM_062938.21 NP_495339.11 |
ENSEMBL Gene Tree for AIP (if available)
TreeFam Gene Tree for AIP (if available) |
Paralogs
for AIP gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for AIP gene
- AIPL12
2 SIMAP similar genes for AIP using alignment to 34 protein entries: AIP_HUMAN (see all proteins):AIPL1 DKFZp686O2183
AIP for paralogs About GeneDecksing
|
Genomic Variants
for AIP gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for AIP (67250505 - 67258579 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for AIP
1 CNV: 5275
Human Gene Mutation Database (HGMD): AIP
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing AIP |
|
Disorders
/ Diseases
for AIP gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
AIP for disorders About GeneDecksing
OMIM gene information: 605555
OMIM disorders: 102200 600634 219090
UniProtKB/Swiss-Prot: AIP_HUMAN, O00170
Defects in AIP are a cause of growth hormone-secreting pituitary adenoma (GHSPA) [MIM:102200]; also known asfamilial isolated somatotropinomas (FIS) or isolated familial somatotropinoma (IFS) or familial somatotrophinoma oracromegaly due to pituitary adenoma Defects in AIP are a cause of ACTH-secreting pituitary adenoma (ASPA) [MIM:219090]; also known as pituitaryCushing disease. A pituary adenoma resulting in excessive production of adrenocorticotropic hormone. This leads tohypersecretion of cortisol by the adrenal glands and ACTH-dependent Cushing syndrome. Clinical manifestations ofCushing syndrome include facial and trunkal obesity, abdominal striae, muscular weakness, osteoporosis, arterialhypertension, diabetes Defects in AIP are a cause of prolactin-secreting pituitary adenoma (PSPA) [MIM:600634]; also known asprolactinoma. Prolactin-secreting pituitary adenoma is the most common type of hormonally active pituitary adenoma
20/30  diseases for AIP (see all 30): About MalaCardsacth-secreting pituitary adenoma hepatitis b growth hormone secreting pituitary adenoma prolactin producing pituitary tumor
pituitary adenoma hepatitis carney complex multiple endocrine neoplasia
pituitary tumor adenoma somatotrophinoma prolactinoma
wermer syndrome acromegaly gigantism brain injury
primary hyperparathyroidism cushing's syndrome hyperparathyroidism noma
6 diseases from the University of Copenhagen DISEASES database for AIP:Hormone producing pituitary cancer Pituitary adenoma Carney complex Wermer syndrome
Acromegaly Adenoma 10 Novoseek disease relationships for AIP gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| pituitary adenoma |
85.6 |
35 |
17916996 (5), 18381572 (3), 19684062 (3), 17893250 (3) (see all 16) |
| acromegaly |
81.4 |
9 |
17371465 (1), 18381572 (1), 17916996 (1), 19883897 (1) (see all 6) |
| prolactinoma |
81.2 |
1 |
17244780 (1) |
| gigantism |
77.6 |
2 |
17371465 (1), 17609395 (1) |
| pituitary tumors |
73 |
15 |
19188737 (4), 17893251 (2), 17916996 (2), 18787049 (1) (see all 6) |
| adenoma |
53.5 |
10 |
17371465 (3), 18381572 (2), 19883897 (2), 17916996 (1) (see all 6) |
| hepatitis b |
41.3 |
9 |
14730974 (2), 9447995 (1), 10777214 (1), 11955954 (1) (see all 8) |
| somatic mutations |
27.3 |
1 |
17371465 (1) |
| shock |
18.7 |
2 |
9837941 (1), 11093792 (1) |
| tumors |
0 |
17 |
17244780 (3), 20454499 (3), 17609395 (2), 18381572 (2) (see all 7) |
Human Genome Epidemiology (HuGE) Navigator: AIP (31 documents)
Export disorders for AIP gene to outside databases
|
Publications
for AIP gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for AIP gene, integrated from 9 sources (see all 111):
(articles sorted by number of sources associating them with AIP) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- XAP2, a novel hepatitis B virus X-associated protein that inhibits X transactivation. (PubMed id 8972861)1, 2, 3, 9 Kuzhandaivelu N.... Seto E. (1996)
- Ligand-dependent interaction of the aryl hydrocarbon receptor with a novel immunophilin homolog in vivo. (PubMed id 9111057)1, 2, 3 Carver L.A. and Bradfield C.A. (1997)
- Aryl hydrocarbon receptor-interacting protein gene mutations in familial isolated pituitary adenomas: analysis in 73 families. (PubMed id 17244780)1, 2, 9 Daly A.F.... Beckers A. (2007)
- Molecular diagnosis of pituitary adenoma predisposition caused by aryl hydrocarbon receptor-interacting protein gene mutations. (PubMed id 17360484)1, 2, 9 Georgitsi M.... Aaltonen L.A. (2007)
- The tyrosine kinase receptor RET interacts in vivo wi th aryl hydrocarbon receptor-interacting protein to alter survivin availability . (PubMed id 19366855)1, 2, 9 Vargiolu M....Bonora E. (2009)
- Aryl hydrocarbon receptor interacting protein (AIP) gene mutation analysis in children and adolescents with sporadic pituitary adenomas. (PubMed id 18410548)1, 2, 9 Georgitsi M.... Aaltonen L.A. (2008)
- Mutations in the aryl hydrocarbon receptor interacting protein gene are not highly prevalent among subjects with sporadic pituitary adenomas. (PubMed id 17299063)1, 2 Barlier A.... Beckers A. (2007)
- Germline mutation in the aryl hydrocarbon receptor interacting protein gene in familial somatotropinoma. (PubMed id 17341560)1, 2 Toledo R.A.... Dahia P.L.M. (2007)
- Pituitary adenoma predisposition caused by germline mutations in the AIP gene. (PubMed id 16728643)1, 2 Vierimaa O....Aaltonen L.A. (2006)
- Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)1, 2 Rush J.... Comb M.J. (2005)
|
External Searches for AIP gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing AIP gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing AIP gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing AIP gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for AIP | Pharmacogenomics, SNPs, Pathways | | ATLAS Chromosomes in Cancer entry for AIP | Genetics and Cytogenetics in Oncology and Haematology | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/AIP |
|
| | |
About This Section
| Patent Information for AIP gene:
Search GeneIP for patents involving AIP
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for AIP gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
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| | |  | OriGene Antibodies for AIP | | OriGene shRNA RFP for AIP | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for AIP | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for AIP | | | OriGene Protein Over-expression Lysate for AIP | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for AIP | | OriGene 3'-UTR Clone for AIP | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for AIP | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for AIP | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for AIP | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for AIP | | OriGene Custom Protein Services for AIP | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat AIP | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing AIP | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AIP | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat AIP | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AIP | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat AIP |
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| | | | Search Tocris compounds for AIP |
| |  |  |  |  | | | | | | Recombinant Protein for AIP |
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 | | | AIP Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AIP |
|  |  |  |  | | | | ThermoFisher Antibody for AIP |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AIP |
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