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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

AIMP2 Gene

protein-coding   GIFtS: 53
GCID: GC07P006016

aminoacyl tRNA synthetase complex-interacting multifunctional...

 Explore 5 diseases affiliated with
AIMP2 via our new
 Human Malady Compendium 
Biological research products
for AIMP2
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Aminoacyl TRNA Synthetase Complex-Interacting Multifunctional Protein 21 2     P382
JTV11 2 3 5     P382
JTV-11 2     Aminoacyl TRNA Synthase Complex-Interacting Multifunctional Protein 22
Multisynthase Complex Auxiliary Component P382 3     ARS-Interacting Multi-Functional Protein 22
Protein JTV-12 3     Multisynthetase Complex Auxiliary Component P382
PRO09921     

External Ids:    HGNC: 206091   Entrez Gene: 79652   Ensembl: ENSG000001063057   OMIM: 6008595   UniProtKB: Q131553   

Export aliases for AIMP2 gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for AIMP2:
The JTV1 gene is located on chromosome 7p22 flanked by two genes, HRI and PMS2. JTV1 and HRI overlap slightly and are
arranged in a tail-to-tail fashion. JTV1 and PMS2 are separated by approximately 200 base pairs and are arranged
head-to-head. JTV1 is transcribed in the opposite direction compared to HRI and PMS2. The function of the JTV1 gene
product is unknown. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: AIMP2_HUMAN, Q13155
Function: Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and
degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar
type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a
proapoptotic factor

Gene Wiki entry for AIMP2 (Multisynthetase complex auxiliary component p38)


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.1  NT_007819.17  NT_079592.2  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for AIMP2
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidAIMP2 promoter sequence
   Search SABiosciences Chromatin IP Primers for AIMP2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AIMP2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p22   Ensembl cytogenetic band:  7p22.1   HGNC cytogenetic band: 7p22.1

AIMP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AIMP2 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P006016:  view genomic region     (about GC identifiers)

Start:
6,048,876 bp from pter      End:
6,063,465 bp from pter
Size:
14,590 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 6,095,227-6,109,810     

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: AIMP2_HUMAN, Q13155 (See protein sequence)
Recommended Name: Aminoacyl tRNA synthase complex-interacting multifunctional protein 2  
Size: 320 amino acids; 35349 Da
Subunit: Component of the aminoacyl-tRNA synthase complex which is comprised of a bifunctional glutamyl-prolyl-tRNA
synthase, the monospecific isoleucyl, leucyl, glutaminyl, methionyl, lysyl, arginyl and aspartyl-tRNA synthases, and
three auxiliary proteins, EEF1E1/p18, AIMP2/p38 and AIMP1/p43. Binds FUBP1 (via C-terminus). Interacts in both its
unphosphorylated and phosphorylated forms with p53/TP53 (via N-terminus) in the nucleus following UV irradiation.
Interacts (via N-terminus) with KARS and PARK2/parkin (via first RING-type domain)
Subcellular location: Cytoplasm, cytosol (By similarity). Nucleus (By similarity). Note=Following DNA damage,
dissociates from the aminoacyl-tRNA synthase complex and translocates from the cytoplasm to the nucleus (By
similarity)
Miscellaneous: Accumulates in brains affected by autosomal-recessive juvenile parkinsonism, idiopathic Parkinson
disease and diffuse Lewy body disease
Sequence caution: Sequence=AAC50391.1; Type=Frameshift; Positions=312;
1 PDB 3D structure from and Proteopedia for AIMP2:
4DPG (3D)    
Secondary accessions: Q75MR1 Q96CZ5 Q9P1L2

Explore the universe of human proteins at neXtProt for AIMP2: NX_Q13155

Post-translational modifications:

  • Phosphorylated on serine residues in response to UV irradiation (By similarity)1
  • Ubiquitinated by PARK2, leading to its degradation by the proteasome. Mutant PARK2 fails to ubiquitinate AIMP2
  • efficiently, allowing its accumulation which may contribute to neurodegeneration associated with Parkinson disease1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q13155

  • AIMP2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_006294.2  
    ENSEMBL proteins: 
     ENSP00000223029   ENSP00000383327   ENSP00000392519   ENSP00000378658  
    Reactome Protein details: Q13155
    Human Recombinant Protein Products: 
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    Novus Biologicals AIMP2 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for AIMP2

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005829cytosol TAS--


    AIMP2 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    AIMP2 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR010987 Glutathione-S-Trfase_C-like

    Graphical View of Domain Structure for InterPro Entry Q13155

    ProtoNet protein and cluster: Q13155

    UniProtKB/Swiss-Prot: AIMP2_HUMAN, Q13155
    Similarity: Contains 1 GST C-terminal domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: AIMP2_HUMAN, Q13155
    Function: Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and
    degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar
    type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a
    proapoptotic factor

    miRNA
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    Inhib. RNA
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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--


    AIMP2 for ontologies           About GeneDecksing


    Animal Models:
         1 MGI mutant phenotype (inferred from 2 alleles(MGI details for Aimp2):
     mortality/aging 

    AIMP2 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1tRNA Aminoacylation
    tRNA Aminoacylation1.00
    Cytosolic tRNA aminoacylation0.57
    2Keap1-Nrf2 Pathway
    Keap1-Nrf2 Pathway1.00
    3Generic Transcription Pathway
    Gene Expression0.46

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 BioSystems Pathway for AIMP2 
        Keap1-Nrf2 Pathway

    3        Reactome Pathways for AIMP2
        Cytosolic tRNA aminoacylation
    tRNA Aminoacylation
    Gene Expression



    AIMP2 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for AIMP2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/62 Interacting proteins for AIMP2 (Q131551, 2, 3 ENSP000002230294) via UniProtKB, MINT, STRING, and/or I2D (see all 62)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    FUBP1Q96AE42, 3, ENSP000003598044MINT-8145530 MINT-8145585 MINT-8145599 I2D: score=3 STRING: ENSP00000359804
    KARSQ150462, 3, ENSP000003254484MINT-66634 MINT-8258901 I2D: score=7 STRING: ENSP00000325448
    DARSP148682, 3, ENSP000002641614MINT-8258842 MINT-66813 I2D: score=5 STRING: ENSP00000264161
    QARSP478972, 3, ENSP000003075674MINT-8145506 MINT-8145517 I2D: score=2 STRING: ENSP00000307567
    EPS8Q129292, 3, ENSP000002811724MINT-67317 I2D: score=5 STRING: ENSP00000281172
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006418tRNA aminoacylation for protein translation TAS--
    GO:0006915apoptotic process IEA--
    GO:0008285negative regulation of cell proliferation IEA--
    GO:0010467gene expression TAS--
    GO:0031398positive regulation of protein ubiquitination IEA--


    AIMP2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    EMD Millipore small molecules for AIMP2:
    Small Molecule - inhibitor
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for AIMP2
    Search CenterWatch for drugs/clinical trials and news about AIMP2 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for AIMP2 gene: 
    NM_006303.3  

    Unigene Cluster for AIMP2:

    Aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
    Hs.301613  [show with all ESTs]
    Unigene Representative Sequence: BQ065837
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000223029(uc003spo.3) ENST00000400479 ENST00000415999 ENST00000395236


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    Additional cDNA sequence: 

    AK313037.1 BC002853.1 BC010156.1 BC013630.1 U24169.1 

    11 DOTS entries:

    DT.100678744  DT.100678754  DT.92466975  DT.100678743  DT.95352077  DT.95367171  DT.211931  DT.121093621 
    DT.121093649  DT.449929  DT.92467022 

    24/600 AceView cDNA sequences (see all 600):

    BG753057 AA773200 BM463369 AW664197 AL557845 CR620181 AW409648 BG057055 
    BQ653869 BU069816 BM835822 AA156494 AA384205 R08914 BU170835 F07068 
    BM982362 AA427870 BM458318 BE298420 BI223396 AF085994 AA428930 BU155504 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for AIMP2    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6
    SP1:                                -     -     -     -                                 
    SP2:                          -     -     -     -                                       
    SP3:                                -           -     -                                 
    SP4:                          -     -     -     -     -                                 
    SP5:                                                  -                                 


    ECgene alternative splicing isoforms for AIMP2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    AIMP2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TAATTTAAAA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See AIMP2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for AIMP2

    SOURCE GeneReport for Unigene cluster: Hs.301613
        SABiosciences Custom PCR Arrays for AIMP2
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    In Situ
    Assay Products:
     

     
    Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for AIMP2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for AIMP2 gene from 6/20 species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Aimp21 , 5 aminoacyl tRNA synthetase complex-interacting multifunctional more1, 5 83.65(n)1
    86.87(a)1
      5 (82.80 cM)5
    2318721  NM_001172146.11  NP_001165617.11 
     1439027045 
    chicken
    (Gallus gallus)
    Aves AIMP21 aminoacyl tRNA synthetase complex-interacting multifunctional more 71.65(n)
    77.18(a)
      769030  XM_003642110.1  XP_003642158.1 
    lizard
    (Anolis carolinensis)
    Reptilia AIMP26
    --
    72(a)
    1 ↔ 1
    GL343507.1(225806-230006)
    African clawed frog
    (Xenopus laevis)
    Amphibia jtv1-prov2 JTV1 gene 75.19(n)    BC043832.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufc09d042 Danio rerio cDNA clone MGC63976 IMAGE6792283, complete more 70.86(n)    BC053178.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG123046
    --
    23(a)
    1 ↔ 1
    3L(15576738-15578447)


    ENSEMBL Gene Tree for AIMP2 (if available)
    TreeFam Gene Tree for AIMP2 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for AIMP2 gene

    AIMP2 for paralogs           About GeneDecksing


    5 Pseudogenes.org Pseudogenes for AIMP2
    PGOHUM00000242860 PGOHUM00000232873 PGOHUM00000233402 PGOHUM00000233430 PGOHUM00000262534


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/302 NCBI SNPs in AIMP2 are shown (see all 302    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1143046611,2
    C,F,--6050791(+) TTATAC/TAGAGG 1 -- int11Minor allele frequency- T:0.03WA 118
    rs771992181,2
    C,--6050796(+) CAGAGG/TAGCAG 1 -- int13Minor allele frequency- T:0.20NA EA 242
    rs132401381,2
    C,F,--6050825(+) TGAATG/AGGACT 1 -- int15Minor allele frequency- A:0.15NA EA 246
    rs1156977521,2
    C,F,--6050882(+) CCAAAG/ATTATA 1 -- int11Minor allele frequency- A:0.03WA 118
    rs752852431,2
    C,--6050909(+) CTCACC/AGCTCA 1 -- int12Minor allele frequency- A:0.04NA 122
    rs1840118751,2
    --6050990(+) GGTAGG/TTTTAG 1 -- int10--------
    rs624561841,2
    C,F,--6051110(+) CAAACG/ATACAT 1 -- int12Minor allele frequency- A:0.50NA WA 4
    rs1885596301,2
    --6051162(+) CACAAG/TATGGG 1 -- int10--------
    rs1931570961,2
    --6051170(+) GGGTGA/TATCGG 1 -- int10--------
    rs784537981,2
    C,--6051209(+) TTGTTA/TTCCTT 1 -- int13Minor allele frequency- T:0.20NA EA 242

    HapMap Linkage Disequilibrium report for AIMP2 (6048876 - 6063465 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for AIMP2
         1 Inversion: 37290

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    AIMP2 for disorders           About GeneDecksing

    OMIM gene information: 600859    OMIM disorders: --

    5 diseases for AIMP2:    About MalaCards
    appendicitis    parkinson's disease    pulmonary disease    neurodegeneration
    immunodeficiency

    Human Genome Epidemiology (HuGE) Navigator: AIMP2 (5 documents)

    Export disorders for AIMP2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for AIMP2 gene, integrated from 9 sources (see all 55):
    (articles sorted by number of sources associating them with AIMP2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. AIMP2/p38, the scaffold for the multi-tRNA synthetase complex, responds to genotoxic stresses via p53. (PubMed id 18695251)1, 2, 3 Han J.M....Kim S. (2008)
    2. Analysis of the 5' region of PMS2 reveals heterogeneous transcripts and a novel overlapping gene. (PubMed id 8666379)1, 2, 3 Nicolaides N.C.... Vogelstein B. (1995)
    3. Macromolecular assemblage of aminoacyl-tRNA synthetases: identification of protein-protein interactions and characterization of a core protein. (PubMed id 9878398)1, 2, 9 Quevillon S.... Mirande M. (1999)
    4. Accumulation of the authentic parkin substrate aminoacyl-tRNA synthetase cofactor, p38/JTV-1, leads to catecholaminergic cell death. (PubMed id 16135753)1, 2 Ko H.S.... Dawson T.M. (2005)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
    7. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
    8. Downregulation of FUSE-binding protein and c-myc by tRNA synthetase cofactor p38 is required for lung cell differentiation. (PubMed id 12819782)1, 2 Kim M.J.... Kim S. (2003)
    9. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    10. Splicing variant of AIMP2 as an effective target again st chemoresistant ovarian cancer. (PubMed id 22532625)1 Choi J.W....Kim S. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 7965 HGNC: 20609 AceView: HRI Ensembl:ENSG00000106305 euGenes: HUgn7965
    ECgene: AIMP2 H-InvDB: AIMP2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for AIMP2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for AIMP2 gene:
    Search GeneIP for patents involving AIMP2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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