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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

AIFM3 Gene

protein-coding GIFtS: 51
GCID: GC22P021322

apoptosis-inducing factor, mitochondrion-associated, 3

Explore 7 diseases affiliated with
AIFM3 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Apoptosis-Inducing Factor, Mitochondrion-Associated, 3¹ ²		Apoptosis-Inducing Factor Like²
AIFL¹ ² ³		EC 1.-.-.-³
FLJ30473¹		Apoptosis-Inducing Factor-Like Protein³
Apoptosis-Inducing Factor 3²

External Ids:	HGNC: 26398¹	Entrez Gene: 150209²	Ensembl: ENSG00000183773⁷	UniProtKB: Q96NN9³

ORGUL members:
	NONCODE:n407897

Export aliases for AIFM3 gene to outside databases

Previous GC identifers: GC22P019649 GC22P021321 GC22P004589

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: AIFM3_HUMAN, Q96NN9

Function: Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000022.10 NC_018933.1 NT_011520.12

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the AIFM3 gene promoter:
POU2F1 POU2F1b POU2F1a Pax-4a E47
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): AIFM3 promoter sequence

Search SABiosciences Chromatin IP Primers for AIFM3

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AIFM3

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q11.21 Ensembl cytogenetic band: 22q11.21 HGNC cytogenetic band: 22q11.21

AIFM3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AIFM3 gene location

GeneLoc information about chromosome 22 GeneLoc Exon Structure

GeneLoc location for GC22P021322: view genomic region (about GC identifiers)

Start:	21,319,396 bp from pter	End:	21,335,649 bp from pter
Size:	16,254 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: AIFM3_HUMAN, Q96NN9 (See protein sequence)

Recommended Name: Apoptosis-inducing factor 3

Size: 605 amino acids; 66791 Da

Subcellular location: Mitochondrion. Note=Does not translocate to the nucleus upon induction of apoptosis

Secondary accessions: B7WP37 D3DX37 D3DX38 Q6ZT44 Q8N1V3 Q8N5E0

Alternative splicing: 3 isoforms: Q96NN9-1 Q96NN9-2 Q96NN9-3 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for AIFM3: NX_Q96NN9

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q96NN9

AIFM3 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (3 alternative transcripts):

NP_001018070.1 NP_001139760.1 NP_653305.1

ENSEMBL proteins:

ENSP00000382120 ENSP00000382116 ENSP00000412973 ENSP00000402067 ENSP00000399657

ENSP00000406989 ENSP00000385800 ENSP00000335369 ENSP00000390798 ENSP00000327671

Human Recombinant Protein Products for AIFM3:

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	Uscn Proteins for AIFM3

Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	NOT nucleus	IDA	15764604
GO:0005737	cytoplasm	IDA	--
GO:0005739	mitochondrion	IDA	--
GO:0005743	mitochondrial inner membrane	IDA	15764604
GO:0005783	endoplasmic reticulum	IDA	15764604

AIFM3 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

AIFM3 for domains About GeneDecksing

5/7 InterPro domains/families (see all 7):

IPR000103 Pyridine_nuc-diS_OxRdtase_2

IPR013027 FAD_pyr_nucl-diS_OxRdtase

IPR017941 Rieske_2Fe-2S

IPR004099 Pyr_nucl-diS_OxRdtase_dimer

IPR016156 FAD/NAD-linked_Rdtase_dimer

Graphical View of Domain Structure for InterPro Entry Q96NN9

ProtoNet protein and cluster: Q96NN9

3 Blocks protein families:

IPB001327 Pyridine nucleotide-disulphide oxidoreductase

IPB005806 Rieske [2Fe-2S] domain

IPB013027 FAD-dependent pyridine nucleotide reductase signature

UniProtKB/Swiss-Prot: AIFM3_HUMAN, Q96NN9

Domain: The Rieske domain induces apoptosis

Similarity: Belongs to the FAD-dependent oxidoreductase family

Similarity: Contains 1 Rieske domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: AIFM3_HUMAN, Q96NN9

Function: Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential

Enzyme Number (IUBMB): EC 1.-.-.-¹

Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	IDA	15764604
GO:0016491	oxidoreductase activity	IEA	--
GO:0046872	metal ion binding	IEA	--
GO:0050660	flavin adenine dinucleotide binding	IEA	--
GO:0051537	2 iron, 2 sulfur cluster binding	IEA	--

AIFM3 for ontologies About GeneDecksing

Phenotypes:
2 GenomeRNAi human phenotypes for AIFM3:

G0/1 arrest

Increased G1 DNA content

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for AIFM3

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		hsa-miR-922 hsa-miR-1271 hsa-miR-590-3p hsa-miR-96
		SwitchGear 3'UTR luciferase reporter plasmid: AIFM3 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AIFM3

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for AIFM3

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

4 Interacting proteins for AIFM3 (Q96NN9³ ENSP00000335369⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
KLHL12	Q53G59³	I2D: score=1
MAGEA11	P43364³	I2D: score=1
PRNP	P04156³	I2D: score=1
--	ENSP00000368748⁴	STRING: ENSP00000368748

About this table

Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006917	induction of apoptosis	IDA	15764604
GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c	IDA	15764604
GO:0022900	electron transport chain	IEA	--
GO:0045454	cell redox homeostasis	IEA	--
GO:0051882	mitochondrial depolarization	IDA	15764604

AIFM3 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for AIFM3

1 HMDB Compound for AIFM3 About this table

Compound	Synonyms	CAS #	PubMed Ids
FAD	1H-Purin-6-amine flavin dinucleotide (see all 21)	146-14-5	--

Search CenterWatch for drugs/clinical trials and news about AIFM3

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for AIFM3 gene (3 alternative transcripts):

NM_001018060.2 NM_001146288.1 NM_144704.2

Unigene Cluster for AIFM3:

Apoptosis-inducing factor, mitochondrion-associated, 3

Hs.723246 [show with all ESTs]

Unigene Representative Sequence: NM_001146288

18/20 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 20):

ENST00000399167(uc002ztk.2 uc002ztj.2) ENST00000399163 ENST00000417515

ENST00000467926 ENST00000441376 ENST00000479523 ENST00000472575 ENST00000495869

ENST00000434714 ENST00000426113 ENST00000468124 ENST00000484206 ENST00000405089(uc002ztl.2 uc011ahx.1)

ENST00000496097 ENST00000465606 ENST00000483107 ENST00000486003 ENST00000335375

miRNA Products:		OriGene 3'-UTR Clone (see all 3): AIFM3 Browse OriGene MicroRNA Expression Plasmids
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		4 QIAGEN miScript miRNA Assays for microRNAs that regulate AIFM3:
		hsa-miR-922 hsa-miR-1271 hsa-miR-590-3p hsa-miR-96
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Additional cDNA sequence:

AK055035.1 AK094844.1 AK295581.1 AK316042.1 BC032485.1 CR456342.1 NR_027464.1

14 DOTS entries:

DT.100779185 DT.100648655 DT.40213016 DT.423376 DT.120667986 DT.95270268 DT.120668195 DT.100809547

DT.95270269 DT.100662270 DT.120668185 DT.120668326 DT.97816117 DT.99949405

24/206 AceView cDNA sequences (see all 206):

BC026214 BM562885 BP349858 BM705145 BQ416972 BM772801 AI932666 BM562907

BU733514 NM_006767 BM773212 AI492536 CA489669 BQ182728 CR626811 BM697448

CR456342 BQ019651 BE673452 BQ427630 AL119038 BM773018 BI334485 BM722768

GeneLoc Exon Structure

5/15 Alternative Splicing Database (ASD) splice patterns (SP) for AIFM3 (see all 15) About this scheme

ExUns:	1a	·	1b	^	2	^	3a	·	3b	·	3c	^	4	^	5a	·	5b	·	5c	·	5d	·	5e	^	6a	·	6b	·	6c	^	7a	·	7b	^	8a	·	8b	^	9	^	10	^	11a	·	11b	^	12	^	13	^	14	^
SP1:																					-		-		-		-		-
SP2:					-		-		-		-				-						-		-		-		-		-
SP3:																																											-
SP4:															-						-		-		-		-		-
SP5:

ExUns:	15	^	16	^	17	^	18a	·	18b	^	19a	·	19b	^	20	^	21	^	22a	·	22b	^	23
SP1:							-														-
SP2:							-														-
SP3:							-
SP4:
SP5:

ECgene alternative splicing isoforms for AIFM3

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

AIFM3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTAGACATTA

About this image
See AIFM3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for AIFM3

SOURCE GeneReport for Unigene cluster: Hs.723246

UniProtKB/Swiss-Prot: AIFM3_HUMAN, Q96NN9

Tissue specificity: Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and

tongue (at protein level)

SABiosciences Expression via Pathway-Focused PCR Array including AIFM3:

Apoptosis 384HT in human mouse rat

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the last universal common ancestor (LUCA).

Orthologs for AIFM3 gene from 8/30 species (see all 30) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	AIFM3¹	apoptosis-inducing factor, mitochondrion-associated, more	76.48(n) 80.94(a)		416999 XM_003642216.1 XP_003642264.1
lizard (Anolis carolinensis)	Reptilia	AIFM3⁶	--	73(a)	1 ↔ 1	GL343417.1(814741-829168)
African clawed frog (Xenopus laevis)	Amphibia	nfrl-A²	neurula-specific ferredoxin reductase-like protein	73.75(n)		D86491.1
zebrafish (Danio rerio)	Actinopterygii	BQ479502.1²	--	69.8(n)		BQ479502.1
fruit fly (Drosophila melanogaster)	Insecta	CG10700¹	CG10700	50.1(n) 38.1(a)		35183 NM_136098.2 NP_609942.1
worm (Caenorhabditis elegans)	Secernentea	F20D6.11¹	Protein F20D6.11	43.99(n) 34.3(a)		179196 NM_072711.3 NP_505112.1
thale cress (Arabidopsis thaliana)	eudicotyledons	MDHAR¹	monodehydroascorbate reductase (NADH)	43.08(n) 28.41(a)		820155 NM_111829.3 NP_566361.1
E. coli (Escherichia coli)	Gamma proteobacteria	nirB⁶ hcaD⁶ (see all 3)	nitrite reductase, large subunit, NAD(P)H-binding phenylpropionate dioxygenase, ferredoxin reductase... (see all 3)	9(a) 23(a) (see all 3)	possible ortholog 1 ↔ 1 (see all 3)	Chromosome(3492033-3494576) Chromosome(2670069-2671271)

ENSEMBL Gene Tree for AIFM3 (if available)
TreeFam Gene Tree for AIFM3 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for AIFM3 gene

AIFM1²

AIFM3 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 22 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs11912974^1,2	C,H	--	4588901(+)	`GGCAGA/GTGGCA`	2	--	us2k¹		0	--	--	--	--
rs113263557^1,2		--	4589568(+)	`GAGTCG/AGGGGT`	2	--	us2k¹		2		CSA WA	120
rs112472055^1,2	C	--	4589777(+)	`TGGAGG/TCTGGG`	2	--	nc-transcript-variantut5¹		2		NA EA	122
rs17551486^1,2	C,F	--	4589926(+)	`GCTAGG/AGGGAG`	2	--	int¹		1		EA	120
rs73164810^1,2	C,F	--	4590084(+)	`AGGGGA/GAGGGG`	2	--	int¹		2		NA EA	240
rs77443098^1,2	F	--	4590248(+)	`CCCCAC/TGCTCT`	2	--	int¹		1		NA	120
rs11334069^1,2	C	--	4590620(+)	`CGTCT-/CCCCCC`	4	--	int¹ trp³		2		NA CSA	4
rs186216120^1,2		--	21317431(+)	`CTATCC/TCTGGG`	2	--	us2k¹		0	--	--	--	--
rs2018682^1,2	C,F,A,H	--	21317432(-)	`CCCCAA/GGGATA`	2	--	us2k¹		23		NS EA WA NA CSA	2343
rs141494844^1,2		--	21317550(+)	`AGCACA/TTTTAG`	2	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for AIFM3 (21319396 - 21335649 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 5 variations for AIFM3
5 CNVs: 5170 50816 30158 6143 50815

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing AIFM3

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

AIFM3 for disorders About GeneDecksing

7 diseases for AIFM3: About MalaCards

gastric cancer pneumonia cerebritis tuberculosis

thyroiditis malaria mycobacterium tuberculosis

Human Genome Epidemiology (HuGE) Navigator: AIFM3 (1 document)

Export disorders for AIFM3 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for AIFM3 gene, integrated from 9 sources (see all 16):
(articles sorted by number of sources associating them with AIFM3)

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Molecular cloning and characterization of a human AIF-like gene with ability to induce apoptosis. (PubMed id 15764604)^{1, 2, 3, 9} Xie Q.... Bonanno J.A. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)^{1, 2} Collins J.E.... Dunham I. (2004)
Downregulation of miR-210 expression inhibits prolifer ation, induces apoptosis and enhances radiosensitivity in hypoxic human hepatoma cells in vitro. (PubMed id 22387901)¹ Yang W....Zhu W. (2012)
[Expression of AIF and CGRP markers in pineal gland an d thymus during aging]. (PubMed id 22550867)¹ Lin'kova N.S....Khavinson V.K.h. (2011)
Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)¹ OlA!h J....OvA!di J. (2011)
Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)¹ Hendrickson S.L....O'Brien S.J. (2010)
Protein microarray analysis identifies human cellular prion protein interactors. (PubMed id 18482256)¹ Satoh J....Tabunoki H. (2009)
H. pylori-induced apoptosis in human gastric cancer cells mediated via the release of apoptosis-inducing factor from mitochondria. (PubMed id 19166416)¹ Ashktorab H....Smoot D.T. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 150209	HGNC: 26398	AceView: LZTR1andFLJ30473	Ensembl:ENSG00000183773	euGenes: HUgn150209
ECgene: AIFM3	H-InvDB: AIFM3

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for AIFM3	Pharmacogenomics, SNPs, Pathways

Intellectual Property for AIFM3 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for AIFM3 gene:
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AIFM3 Gene

apoptosis-inducing factor, mitochondrion-associated, 3

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apoptosis-inducing factor, mitochondrion-associated, 3

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