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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

AIFM2 Gene

protein-coding   GIFtS: 52
GCID: GC10M071857

apoptosis-inducing factor, mitochondrion-associated, 2

(Previous name: apoptosis-inducing factor (AIF)-like mitochondrion-associated...)
(Previous symbol: AMID)
 Explore 3 diseases affiliated with
AIFM2 via our new
 Human Malady Compendium 
Biological research products
for AIFM2
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Apoptosis-Inducing Factor, Mitochondrion-Associated, 21 2     RP11-367H5.22
AMID1 2 3     Apoptosis-Inducing Factor (AIF)-Homologous Mitochondrion-Associated Inducer Of
Death2
PRG31 2 3     Apoptosis-Inducing Factor 22
Apoptosis-Inducing Factor (AIF)-Like Mitochondrion-Associated Inducer Of Death1 2     EC 1.-.-.-3
P53-Responsive Gene 3 Protein2 3     Apoptosis-Inducing Factor Homologous Mitochondrion-Associated Inducer Of Death3
FLJ144971     Apoptosis-Inducing Factor-Like Mitochondrion-Associated Inducer Of Death3

External Ids:    HGNC: 214111   Entrez Gene: 848832   Ensembl: ENSG000000422867   OMIM: 6051595   UniProtKB: Q9BRQ83   

Export aliases for AIFM2 gene to outside databases

Previous GC identifers: GC10M071528 GC10M065864


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for AIFM2:
This gene encodes a flavoprotein oxidoreductase that binds single stranded DNA and is thought to contribute to
apoptosis in the presence of bacterial and viral DNA. The expression of this gene is also found to be induced by tumor
suppressor protein p53 in colon cancer cells. (provided by RefSeq, Nov 2010)

UniProtKB/Swiss-Prot: AIFM2_HUMAN, Q9BRQ8
Function: Oxidoreductase, which may play a role in mediating a p53/TP53-dependent apoptosis response. Probable
oxidoreductase that acts as a caspase-independent mitochondrial effector of apoptotic cell death. Binds to DNA in a
sequence-independent manner. May contribute to genotoxin-induced growth arrest

Gene Wiki entry for AIFM2


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NC_018921.1  NT_030059.13  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the AIFM2 gene promoter:
         AhR   Pax-5   AP-1   ATF-2   Arnt   GATA-1   FOXL1   CREB   FOXO4   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): AIFM2 promoter sequence
   Search SABiosciences Chromatin IP Primers for AIFM2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AIFM2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q22.1   Ensembl cytogenetic band:  10q22.1   HGNC cytogenetic band: 10q22.2

AIFM2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AIFM2 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M071857:  view genomic region     (about GC identifiers)

Start:
71,857,979 bp from pter      End:
71,892,690 bp from pter
Size:
34,712 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: AIFM2_HUMAN, Q9BRQ8 (See protein sequence)
Recommended Name: Apoptosis-inducing factor 2  
Size: 373 amino acids; 40527 Da
Cofactor: FAD. Binds 6-hydroxy-FAD non-covalently
Subcellular location: Cytoplasm. Mitochondrion outer membrane
Secondary accessions: B3KXI0 Q63Z39
Alternative splicing: 2 isoforms:  Q9BRQ8-1   Q9BRQ8-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for AIFM2: NX_Q9BRQ8

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9BRQ8

  • AIFM2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_116186.1  NP_001185625.1  

    ENSEMBL proteins: 
     ENSP00000362345   ENSP00000312370  

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    Uscn Proteins for AIFM2

    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA12135761
    GO:0005739mitochondrion IDA11980907
    GO:0005741mitochondrial outer membrane IDA11980907
    GO:0005811lipid particle IDA14741744
    GO:0005829cytosol IDA11980907


    AIFM2 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    AIFM2 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR000103 Pyridine_nuc-diS_OxRdtase_2
     IPR013027 FAD_pyr_nucl-diS_OxRdtase
     IPR001327 Pyr_OxRdtase_NAD-bd_dom
     IPR023753 Pyr_nucl-diS_OxRdtase_FAD/NAD

    Graphical View of Domain Structure for InterPro Entry Q9BRQ8

    ProtoNet protein and cluster: Q9BRQ8

    2 Blocks protein families:
    IPB000103 Pyridine nucleotide-disulphide oxidoreductase
    IPB001327 Pyridine nucleotide-disulphide oxidoreductase


    UniProtKB/Swiss-Prot: AIFM2_HUMAN, Q9BRQ8
    Similarity: Belongs to the FAD-dependent oxidoreductase family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: AIFM2_HUMAN, Q9BRQ8
    Function: Oxidoreductase, which may play a role in mediating a p53/TP53-dependent apoptosis response. Probable
    oxidoreductase that acts as a caspase-independent mitochondrial effector of apoptotic cell death. Binds to DNA in a
    sequence-independent manner. May contribute to genotoxin-induced growth arrest
    Induction: Expression detected at 4 hours after induction by p53/TP53. Down-regulated in a wide range of human tumors

    Enzyme Number (IUBMB): EC 1.-.-.-1

    miRNA
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    8/14 QIAGEN miScript miRNA Assays for microRNAs that regulate AIFM2 (see all 14):
    hsa-miR-485-5p hsa-miR-600 hsa-miR-137 hsa-miR-92a hsa-miR-367 hsa-miR-25 hsa-miR-32 hsa-miR-1912
    SwitchGear 3'UTR luciferase reporter plasmidAIFM2 3' UTR sequence
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IDA15958387
    GO:0004174electron-transferring-flavoprotein dehydrogenase activity IDA15958387
    GO:0050660flavin adenine dinucleotide binding IDA15958387


    AIFM2 for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-out Aifm2tm1Hbsh for AIFM2
         3 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Aifm2):
     cellular  reproductive system  tumorigenesis 

    AIFM2 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Direct p53 effectors
    Direct p53 effectors1.00


    1 BioSystems Pathway for AIFM2 
        Direct p53 effectors


    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for AIFM2

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for AIFM2 (Q9BRQ83 ENSP000003123704) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    TP53ENSP000002693054STRING: ENSP00000269305
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006917induction of apoptosis IMP11980907
    GO:0008637apoptotic mitochondrial changes NAS11980907
    GO:0030261chromosome condensation IDA11980907


    AIFM2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for AIFM2

    1 HMDB Compound for AIFM2    About this table
    CompoundSynonyms CAS #PubMed Ids
    FAD1H-Purin-6-amine flavin dinucleotide (see all 21)146-14-5--
    Search CenterWatch for drugs/clinical trials and news about AIFM2 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for AIFM2 gene (2 alternative transcripts): 
    NM_032797.5  NM_001198696.1  

    Unigene Cluster for AIFM2:

    Apoptosis-inducing factor, mitochondrion-associated, 2
    Hs.650680  [show with all ESTs]
    Unigene Representative Sequence: NM_001198696
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000373248(uc010qjg.2) ENST00000307864(uc021psi.1 uc001jqp.2)
    ENST00000482166

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    hsa-miR-485-5p hsa-miR-600 hsa-miR-137 hsa-miR-92a hsa-miR-367 hsa-miR-25 hsa-miR-32 hsa-miR-1912
    SwitchGear 3'UTR luciferase reporter plasmidAIFM2 3' UTR sequence
    Inhib. RNA
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    Additional cDNA sequence: 

    AF506757.1 AK027403.1 BC006121.1 BC023601.2 

    14 DOTS entries:

    DT.454747  DT.101982661  DT.100783285  DT.100792928  DT.100665228  DT.102829849  DT.97862695  DT.92426002 
    DT.92426003  DT.100783287  DT.101957929  DT.121261095  DT.121261116  DT.97842335 

    24/143 AceView cDNA sequences (see all 143):

    AK127353 BG332787 AW016581 CD634367 CB215085 CA314960 BC006121 AF506757 
    BU158922 AW239408 AL556311 AI922797 BC023601 BG775126 BF198007 NM_032797 
    BQ635940 AK027403 BU173890 CD514797 AL555902 BX283086 BU732124 CR622972 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    AIFM2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GCACCCGCCT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See AIFM2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for AIFM2

    SOURCE GeneReport for Unigene cluster: Hs.650680

    UniProtKB/Swiss-Prot: AIFM2_HUMAN, Q9BRQ8
    Tissue specificity: Detected in most normal tissues as two transcripts of 1.8 and 4.0 kb in length, respectively.
    Highly expressed in heart, moderately in liver and skeletal muscles, and expressed at low levels in placenta, lung,
    kidney, and pancreas. Both transcripts expressed following p53/TP53 induction. The shorter 1.8 kb transcript seems to
    be the major transcript in EB1 colon cancer cells

        SABiosciences Expression via Pathway-Focused PCR Arrays including AIFM2: 
              Mitochondria in human mouse rat
              Apoptosis 384HT in human mouse rat

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AIFM2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for AIFM2 gene from 7/23 species (see all 23)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Aifm21 , 5 apoptosis-inducing factor, mitochondrion-associated more1, 5 86.68(n)1
    90.35(a)1
      10 (32.27 cM)5
    713611  NM_001039194.31  NP_001034283.11 
     617152635 
    chicken
    (Gallus gallus)
    Aves AIFM21 apoptosis-inducing factor, mitochondrion-associated, more 69.27(n)
    69.89(a)
      423720  XM_421597.3  XP_421597.1 
    lizard
    (Anolis carolinensis)
    Reptilia AIFM26
    --
    68(a)
    1 ↔ 1
    3(48794417-48804765)
    African clawed frog
    (Xenopus laevis)
    Amphibia BJ057663.12   -- 69.86(n)    BJ057663.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5575071 apoptosis-inducing factor, mitochondrion-associated more 58.42(n)
    56.45(a)
      557507  NM_001200010.1  NP_001186939.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G221401 FAD/NAD(P)-binding oxidoreductase family protein 44.16(n)
    33.33(a)
      832275  NM_147895.2  NP_680200.1 
    rice
    (Oryza sativa)
    Liliopsida Os02g01503001 hypothetical protein 44.26(n)
    34.1(a)
      4328310  NM_001052436.1  NP_001045901.1 


    ENSEMBL Gene Tree for AIFM2 (if available)
    TreeFam Gene Tree for AIFM2 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/411 NCBI SNPs in AIFM2 are shown (see all 411    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs412779701,2
    --71872544(+) ATCTCG/TCCCAA 2 -- ut310--------
    rs412779721,2
    C,F,--71872558(+) GAGGAA/CTCATT 2 -- ut311Minor allele frequency- C:0.03NA 120
    rs108234841,2
    C,F,A,H,--71872572(+) ACACTG/TTAACA 2 -- ut31 ese325Minor allele frequency- T:0.29NA NS EA WA 2902
    rs412779741,2
    C,F,--71872718(+) TCACTT/CACAAA 2 -- ut312Minor allele frequency- C:0.09WA NA 238
    rs1849739521,2
    --71872843(+) AAACAC/TCTCCA 2 -- ut310--------
    rs78931371,2
    C,F,A,H,--71872947(+) AGCTCT/ATTCTT 2 -- ut31 trp38Minor allele frequency- A:0.28NS EA WA NA 770
    rs1414493471,2
    --71873105(+) GTGAAA/GCCCCG 2 -- ut310--------
    rs1508260271,2
    --71873274(+) CGAGAC/TTGTCT 2 -- ut310--------
    rs1887875541,2
    --71873290(+) ATAAAC/TAAACA 2 -- ut310--------
    rs109991431,2
    C,F,H,--71873325(+) AGGAAG/TGCCAT 2 -- ut3114Minor allele frequency- T:0.08NS EA NA 1650

    HapMap Linkage Disequilibrium report for AIFM2 (71857979 - 71892690 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for AIFM2
         1 CNV: 6879

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    AIFM2 for disorders           About GeneDecksing

    OMIM gene information: 605159    OMIM disorders: --

    3 diseases for AIFM2:    About MalaCards
    colon cancer    epithelial ovarian cancer    ovarian cancer

    Human Genome Epidemiology (HuGE) Navigator: AIFM2 (3 documents)

    Export disorders for AIFM2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for AIFM2 gene, integrated from 9 sources (see all 25):
    (articles sorted by number of sources associating them with AIFM2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The human apoptosis-inducing protein AMID is an oxidoreductase with a modified flavin cofactor and DNA binding activity. (PubMed id 15958387)1, 2, 3, 9 Marshall K.R.... Munro A.W. (2005)
    2. AMID, an apoptosis-inducing factor-homologous mitochondrion- associated protein, induces caspase-independent apoptosis. (PubMed id 11980907)1, 2, 3 Wu M.... Shu H.-B. (2002)
    3. A novel p53-inducible apoptogenic gene, PRG3, encodes a homologue of the apoptosis-inducing factor (AIF). (PubMed id 12135761)1, 2, 3 Ohiro Y.... Horikoshi N. (2002)
    4. AMID is a p53-inducible gene downregulated in tumors. (PubMed id 15273740)1, 2 Wu M.... Shu H.-B. (2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    7. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (2004)
    8. Functional genomics identifies therapeutic targets for MYC-driven cancer. (PubMed id 22623531)1 Toyoshima M....Grandori C. (2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    10. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 84883 HGNC: 21411 AceView: AMID Ensembl:ENSG00000042286 euGenes: HUgn84883
    ECgene: AIFM2 H-InvDB: AIFM2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for AIFM2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for AIFM2 gene:
    Search GeneIP for patents involving AIFM2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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