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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

AHSA1 Gene

protein-coding   GIFtS: 61
GCID: GC14P077924

AHA1, Activator Of Heat Shock 90kDa Protein ATPase Homolog...

(Previous name: chromosome 14 open reading frame 3)
(Previous symbol: C14orf3)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
AHA1, Activator Of Heat Shock 90kDa Protein ATPase Homolog 1
(Yeast)1 2
C14orf31 2 3
AHA12 3
p382 3
Chromosome 14 Open Reading Frame 31
Activator Of 90 KDa Heat Shock Protein ATPase Homolog 12

External Ids:    HGNC: 11891   Entrez Gene: 105982   Ensembl: ENSG000001005917   OMIM: 6084665   UniProtKB: O954333   

Export aliases for AHSA1 gene to outside databases

Previous GC identifers: GC14P075914 GC14P076994 GC14P058090


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for AHSA1 Gene: 
AHSA1 (AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)) is a protein-coding gene. Diseases associated with AHSA1 include cannabis abuse, and stomatitis, and among its related super-pathways are Mechanisms of CFTR activation by S-nitrosoglutathione (normal and CF). GO annotations related to this gene include ATPase activator activity and chaperone binding. An important paralog of this gene is AHSA2.

UniProtKB/Swiss-Prot: AHSA1_HUMAN, O95433
Function: Cochaperone that stimulates HSP90 ATPase activity (By similarity). May affect a step in the endoplasmic
reticulum to Golgi trafficking

Gene Wiki entry for AHSA1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000014.8  NT_026437.12  NC_018925.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the AHSA1 gene promoter:
         ISGF-3   RP58   FOXF2   Pax-5   MIF-1   MZF-1   IRF-2   PPAR-gamma1   c-Myb   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidAHSA1 promoter sequence
   Search SABiosciences Chromatin IP Primers for AHSA1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AHSA1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q24   Ensembl cytogenetic band:  14q24.3   HGNC cytogenetic band: 14q

AHSA1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AHSA1 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14P077924:  view genomic region     (about GC identifiers)

Start:
77,924,213 bp from pter      End:
77,935,817 bp from pter
Size:
11,605 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: AHSA1_HUMAN, O95433 (See protein sequence)
Recommended Name: Activator of 90 kDa heat shock protein ATPase homolog 1  
Size: 338 amino acids; 38274 Da
Subunit: Interacts with HSPCA/HSP90 and with the cytoplasmic tail of the vesicular stomatitis virus glycoprotein
(VSV G). Interacts with GCH1. Interacts with SRPK1
Subcellular location: Cytoplasm, cytosol. Endoplasmic reticulum. Note=May transiently interact with the
endoplasmic reticulum
1 PDB 3D structure from and Proteopedia for AHSA1:
1X53 (3D)    
Secondary accessions: B2R9L2 Q96IL6 Q9P060

Explore the universe of human proteins at neXtProt for AHSA1: NX_O95433

Explore proteomics data for AHSA1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O95433

  • AHSA1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    AHSA1 Protein Expression
    REFSEQ proteins: NP_036243.1  
    ENSEMBL proteins: 
     ENSP00000451569   ENSP00000216479   ENSP00000440108   ENSP00000451467   ENSP00000451475  
     ENSP00000452127   ENSP00000450890   ENSP00000451474  

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    Browse Sino Biological Cell Lysates 
    ProSpec Recombinant Protein for AHSA1
    Cloud-Clone Corp. Proteins for AHSA1 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm ISS--
    GO:0005783endoplasmic reticulum IEA--
    GO:0005829cytosol IEA--

    AHSA1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR015310 AHSA1_N
     IPR023393 START-like_dom
     IPR013538 Activator_of_Hsp90_ATPase

    Graphical View of Domain Structure for InterPro Entry O95433

    ProtoNet protein and cluster: O95433

    1 Blocks protein domain: IPB013538 Activator of Hsp90 ATPase homologue 1-like

    UniProtKB/Swiss-Prot: AHSA1_HUMAN, O95433
    Similarity: Belongs to the AHA1 family


    AHSA1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: AHSA1_HUMAN, O95433
    Function: Cochaperone that stimulates HSP90 ATPase activity (By similarity). May affect a step in the endoplasmic
    reticulum to Golgi trafficking
    Induction: By heat shock and treatment with the HSP90 inhibitor 17-demethoxygeldanamycin (17AAG)

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001671ATPase activator activity ISS--
    GO:0005515protein binding IPI12604615
    GO:0051087chaperone binding IDA12504007
         
    AHSA1 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for AHSA1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for AHSA1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for AHSA1 
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    miRNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for AHSA1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1CFTR folding and maturation (norm and CF)
    CFTR folding and maturation (norm and CF)0.37
    Mechanisms of CFTR activation by S-nitrosoglutathione (normal and CF)0.37

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 GeneGo (Thomson Reuters) Pathways for AHSA1
        Mechanisms of CFTR activation by S-nitrosoglutathione (normal and CF)
    CFTR folding and maturation (norm and CF)



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for AHSA1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/231 Interacting proteins for AHSA1 (O954331, 2, 3 ENSP000002164794) via UniProtKB, MINT, STRING, and/or I2D (see all 231)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GCH1P307931, 3, ENSP000003788904EBI-448610,EBI-958183 I2D: score=4 STRING: ENSP00000378890
    CCT6AP402272, 3, ENSP000002756034MINT-8380842 I2D: score=2 STRING: ENSP00000275603
    CCT4P509912, 3MINT-8380842 I2D: score=2 
    HSPA8P111422, 3MINT-8380842 I2D: score=1 
    TCP1P179872, 3MINT-8380842 I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006457protein folding ISS--
    GO:0006950response to stress ISS--
    GO:0032781positive regulation of ATPase activity ISS--

    AHSA1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for AHSA1

    Search CenterWatch for drugs/clinical trials and news about AHSA1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    About This Section

    REFSEQ mRNAs for AHSA1 gene: 
    NM_012111.2  

    Unigene Cluster for AHSA1:

    AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
    Hs.204041  [show with all ESTs]
    Unigene Representative Sequence: BF686657
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000555133 ENST00000216479(uc001xtw.3) ENST00000535854(uc010tvk.1)
    ENST00000554156 ENST00000555517 ENST00000556963 ENST00000556866 ENST00000553374
    ENST00000555457 ENST00000555729 ENST00000555473 ENST00000556369 ENST00000557476

    miRNA
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    Additional mRNA sequence: 

    AF161440.1 AF164791.1 AJ243310.1 AK313824.1 BC000321.2 BC007398.2 

    16 DOTS entries:

    DT.80100636  DT.100766646  DT.100816509  DT.40200794  DT.92455890  DT.99935491  DT.100826345  DT.102832228 
    DT.120768451  DT.95358624  DT.95358625  DT.100826349  DT.100826355  DT.120768455  DT.92455894  DT.97790522 

    24/544 AceView cDNA sequences (see all 544):

    AA135643 BQ073652 CA778176 BM722592 CR606034 BQ217021 BQ957156 BQ951152 
    BE274393 BE797345 AW178046 BU679786 CR608181 BQ006223 BQ679871 BM550824 
    AA156924 BM679241 CA414005 BU155978 AW161228 CR618207 AI187984 CR617792 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for AHSA1 (see all 8)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3a · 3b · 3c ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b · 6c ^ 7a · 7b · 7c ^ 8a · 8b ^ 9 ^ 10 ^ 11
    SP1:                                            -           -                                                                       -         
    SP2:        -     -     -     -                 -           -                                                                                 
    SP3:                                            -           -           -     -                                                               
    SP4:                                                                                                                                          
    SP5:                                            -           -     -     -                                                                     


    ECgene alternative splicing isoforms for AHSA1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    AHSA1 expression in normal human tissues (normalized intensities)      AHSA1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTTTCTGCTG
    AHSA1 Expression
    About this image


    AHSA1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/25 selected tissues (see all 25) fully expand
     
     Testis (Reproductive System)    fully expand to see all 4 entries
             Leydig Cells Testis Interstitium
             seminal vesicle ; glandular cells   
     
     Colon (Gastrointestinal Tract)    fully expand to see all 4 entries
             colon ; peripheral nerve/ganglion   
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Uterus (Reproductive System)    fully expand to see all 3 entries
             uterus, post-menopause ; glandular cells   
     
     Pancreas (Endocrine System)    fully expand to see all 2 entries
             Islets of Langerhans
             pancreas ; exocrine glandular cells   

    See AHSA1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for AHSA1

    SOURCE GeneReport for Unigene cluster: Hs.204041

    UniProtKB/Swiss-Prot: AHSA1_HUMAN, O95433
    Tissue specificity: Expressed in numerous tissues, including brain, heart, skeletal muscle and kidney and, at
    lower levels, liver and placenta

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AHSA1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for AHSA1 gene from 10/24 species (see all 24)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ahsa11 , 5 AHA1, activator of heat shock protein ATPase homolog more5
    AHA1, activator of heat shock protein ATPase 11
    91.03(n)1
    94.97(a)1
      12 (41.47 cM)5
    2177371  NM_146036.11  NP_666148.11 
     872667285 
    chicken
    (Gallus gallus)
    Aves AHSA11 AHA1, activator of heat shock 90kDa protein ATPase more 74.26(n)
    77.22(a)
      423378  XM_421292.2  XP_421292.1 
    lizard
    (Anolis carolinensis)
    Reptilia AHSA16
    Uncharacterized protein
    76(a)
    1 ↔ 1
    1(20673932-20690649)
    African clawed frog
    (Xenopus laevis)
    Amphibia BC041491.12   -- 74.52(n)    BC041491.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BC055523.12   -- 79.16(n)    BC055523.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG14161 CG1416 51.49(n)
    44.05(a)
      35426  NM_165398.1  NP_724361.1 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_C01G10.81 Protein C01G10.8 50.55(n)
    38.81(a)
      180017  NM_074314.3  NP_506715.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes AHA1(YDR214W)4
    AHA11
    Co-chaperone that binds to Hsp82p and activates its more4
    Aha1p1
    43.55(n)1
    29.35(a)1
      4(892875-893927)4
    8518001, 4  NP_010500.31  NP_010500.14 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT3G120501 Aha1 domain-containing protein 44.71(n)
    34.44(a)
      820379  NM_112039.2  NP_566410.1 
    rice
    (Oryza sativa)
    Liliopsida Os.80272 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 80(n)    AK059195.1 


    ENSEMBL Gene Tree for AHSA1 (if available)
    TreeFam Gene Tree for AHSA1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for AHSA1 gene
    AHSA22  
    18/28 SIMAP similar genes for AHSA1 using alignment to 8 protein entries:     AHSA1_HUMAN (see all proteins) (see all similar genes):
    RPS6KA5    FAM138A    FAM138B    FAM138C    FAM138F    C14orf105
    OK/SW-cl.41    PLA2G15    DNAPTP3    FAM138D    LOC100996426    LINC00269
    SIPA1L3    ZNF85    LOC100996577    LSM12    CHEK2    FP6651

    AHSA1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for AHSA1
    PGOHUM00000263040


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/323 SNPs in AHSA1 are shown (see all 323)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs10616291,2
    C,F,O,A,H--77926011(+) TGTTCC/TTGGCA 2 L syn1 ese328Minor allele frequency- T:0.43MN NA NS EA WA EU 8601
    rs1475376641,2
    C--77926034(+) AATGAA/CGAAGG 2 E D mis10--------
    rs1461867941,2
    F--77926055(+) GTGACG/AGAAGT 2 /T syn11Minor allele frequency- A:0.01NA 4552
    rs1887461121,2
    --77926265(+) GTTGCG/TGCTTT 1 -- int10--------
    rs752514531,2
    F--77926378(+) TGGCCA/GGGCCA 1 -- int10--------
    rs45316691,2
    C,F,H--77926398(+) TGGGCC/TTTGGT 1 -- int110Minor allele frequency- T:0.06NS EA NA 680
    rs1929563441,2
    --77926443(+) ACTAGC/TTACAT 1 -- int10--------
    rs1844687991,2
    --77926451(+) CATGTA/GTCTTG 1 -- int10--------
    rs1440125701,2
    --77926482(+) AGGAGA/GGGATT 1 -- int10--------
    rs783233951,2
    --77926552(+) GCGCTA/GATGAA 1 -- int10--------

    HapMap Linkage Disequilibrium report for AHSA1 (77924213 - 77935817 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for AHSA1:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv273322CNV Insertion20981092
    esv269366CNV Insertion20981092
    nsv832835CNV Gain17160897

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 608466    OMIM disorders: --

    4 diseases for AHSA1:    About MalaCards
    cannabis abuse    stomatitis    cystic fibrosis    endotheliitis

    1 disease from the University of Copenhagen DISEASES database for AHSA1:
    Cannabis abuse

    AHSA1 for disorders           About GeneDecksing


    Export disorders for AHSA1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for AHSA1 gene, integrated from 9 sources (see all 43):
    (articles sorted by number of sources associating them with AHSA1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Aha1 binds to the middle domain of Hsp90, contributes to client protein activation, and stimulates the ATPase activity of the molecular chaperone. (PubMed id 12604615)1, 2, 9 Lotz G.P.... Obermann W.M.J. (2003)
    2. A yeast 2-hybrid analysis of human GTP cyclohydrolase I protein interactions. (PubMed id 16696853)1, 2 Swick L. and Kapatos G. (2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. The DNA sequence and analysis of human chromosome 14. (PubMed id 12508121)1, 2 Heilig R.... Weissenbach J. (2003)
    5. Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1. (PubMed id 12504007)1, 2 Panaretou B....Prodromou C. (2002)
    6. p38: a novel protein that associates with the vesicular stomatitis virus glycoprotein. (PubMed id 11554768)1, 2 Sevier C.S. and Machamer C.E. (2001)
    7. Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PubMed id 10931946)1, 2 Hu R.-M.... Chen J.-L. (2000)
    8. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (2000)
    9. Chaperone displacement from mutant cystic fibrosis transmembrane conductance regulator restores its function in human airway epithelia. (PubMed id 18556464)1, 9 Sun F....Frizzell R.A. (2008)
    10. Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis. (PubMed id 17110338)1, 9 Wang X....Balch W.E. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10598 HGNC: 1189 AceView: AHSA1 Ensembl:ENSG00000100591 euGenes: HUgn10598
    ECgene: AHSA1 H-InvDB: AHSA1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for AHSA1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for AHSA1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for AHSA1 gene:
    Search GeneIP for patents involving AHSA1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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