AHCYL1 Gene
protein-coding GIFtS: 59
GCID: GC01P110529
|
|
adenosylhomocysteinase-like 1(Previous name: S-adenosylhomocysteine hydrolase-like 1 )
| |
Aliases
for AHCYL1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Adenosylhomocysteinase-Like 11 2 | | EC 3.3.1.13 8 | | XPVKONA1 2 3 | | S-Adenosylhomocysteine Hydrolase-Like 11 | | IRBIT1 2 | | PRO02332 | | AdoHcyase 22 3 | | Dendritic Cell Expressed AHCY-Like Protein2 | | DCAL2 3 | | Inositol 1,4,5-Trisphosphate Receptor-Binding Protein2 | | DC-Expressed AHCY-Like Molecule2 3 | | Putative Adenosylhomocysteinase 22 | | S-Adenosyl-L-Homocysteine Hydrolase 22 3 | | S-Adenosyl Homocysteine Hydrolase Homolog2 | | S-Adenosylhomocysteine Hydrolase-Like Protein 12 3 | | |
Export aliases for AHCYL1 gene to outside databasesPrevious GC identifers: GC01P110943 GC01P109393 GC01P109629 GC01P109826 GC01P110239 GC01P110328 GC01P108396 |
Summaries
for AHCYL1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for AHCYL1:
The protein encoded by this gene interacts with inositol 1,4,5-trisphosphate receptor, type 1 and may be involved inthe conversion of S-adenosyl-L-homocysteine to L-homocysteine and adenosine. Several transcript variants encoding twodifferent isoforms have been found for this gene. (provided by RefSeq, Jun 2011)
Gene Wiki entry for AHCYL1
|
Genomic Views
for AHCYL1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_032977.9
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the AHCYL1 gene promoter:
ISGF-3 AML1a POU3F2 C/EBPalpha Roaz CREB HFH-1 IRF-7A MRF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for AHCYL1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AHCYL1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p13.2 Ensembl cytogenetic band: 1p13.3 HGNC cytogenetic band: 1p13AHCYL1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P110529: view genomic region
(about GC identifiers)
Start:
|
110,527,308 bp from pter |
End:
|
110,566,364 bp from pter |
Size:
|
39,057 bases |
Orientation:
|
plus strand |
|
Proteins
for AHCYL1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SAHH2_HUMAN, O43865 (See
protein sequence)Recommended Name: Putative adenosylhomocysteinase 2 Size: 530 amino acids; 58951 Da
Cofactor: Binds 1 NAD per subunit
Subunit: Interacts with ITPR1. Competes with IP3 for interaction with ITPR1 and attenuates IP3-induced Ca(2+) releasethrough the ITPR1 from the non-mitochondrial intracellular stores (By similarity)
Subcellular location: Endoplasmic reticulum (By similarity)
Developmental stage: Expression increases markedly during activation of blood and skin DC (Langerhans cells), but isdiminished in terminally differentiated tonsil DC
Sequence caution: Sequence=AAC01960.1; Type=Erroneous initiation; Sequence=BI460083; Type=Frameshift;Positions=Several; Sequence=CAB43223.2; Type=Erroneous initiation;
1 PDB 3D structure from  and Proteopedia  for AHCYL1:3MTG (3D)
Secondary accessions: B4E168 Q2TAJ6 Q502W8 Q5VSM0 Q6P171 Q96PK4 Q9UG84Alternative splicing: 2 isoforms: O43865-1 O43865-2 (Derived from EST data)Explore the universe of human proteins at neXtProt for AHCYL1: NX_O43865
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O43865
4/22 DME Specific Peptides for AHCYL1 (O43865) (see all 22)
AHCYL1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (5 alternative transcripts):
NP_001229602.1 NP_001229603.1 NP_001229604.1 NP_001229605.1 NP_006612.2
ENSEMBL proteins: ENSP00000358814 ENSP00000352092 ENSP00000377238
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005783 | endoplasmic reticulum |
IEA | -- |
AHCYL1 for ontologies About GeneDecksing
AHCYL1 Antibody Products:
Assay Products for AHCYL1: |
Protein
Domains /
Families
for AHCYL1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
AHCYL1 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O43865ProtoNet protein and cluster: O43865 1 Blocks protein family: IPB000043 S-adenosyl-L-homocysteine hydrolase
UniProtKB/Swiss-Prot: SAHH2_HUMAN, O43865Domain: The PEST region is essential for the interaction with ITPR1. The PDZ-binding region is required for maximalinteraction with ITPR1 and is also responsible for the IP3-insensitive interaction with ITPR1 (By similarity)Similarity: Belongs to the adenosylhomocysteinase family |
Function
for AHCYL1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SAHH2_HUMAN, O43865Catalytic activity: S-adenosyl-L-homocysteine + H(2)O = L-homocysteine + adenosine Genatlas biochemistry entry for AHCYL1:S-adenosylhomocysteine hydrolase-like 1
Enzyme Number (IUBMB): EC 3.3.1.11 2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for AHCYL1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for AHCYL1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: AHCYL1 (NM_006621) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for AHCYL1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AHCYL1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AHCYL1 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000166 | nucleotide binding |
IEA | -- | | GO:0004013 | adenosylhomocysteinase activity |
IEA | -- | | GO:0005515 | protein binding |
IPI | -- |
AHCYL1 for ontologies About GeneDecksing
7 GenomeRNAi human phenotypes for AHCYL1:
|
Pathways & Interactions
for AHCYL1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Methionine metabolism | | | 2 | Metabolism | | | 3 | Sulfur amino acid metabolism | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for AHCYL1
1  GeneGo (Thomson Reuters) Pathway for AHCYL1
3  BioSystems Pathways for AHCYL1
2 
Kegg Pathways (Kegg details for AHCYL1):
UniProtKB/Swiss-Prot: SAHH2_HUMAN, O43865Pathway: Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1
AHCYL1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for AHCYL1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 19)
5/23 Interacting proteins for AHCYL1 (O438651, 3 ENSP000003588144) via UniProtKB, MINT, STRING, and/or I2D (see all 23)
About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006378 | mRNA polyadenylation |
IEA | -- | | GO:0006611 | protein export from nucleus |
IEA | -- | | GO:0006730 | one-carbon metabolic process |
IEA | -- | | GO:0010765 | positive regulation of sodium ion transport |
IEA | -- | | GO:0031440 | regulation of mRNA 3'-end processing |
IEA | -- |
AHCYL1 for ontologies About GeneDecksing
|
Drugs & Compounds
for AHCYL1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
AHCYL1 for compounds About GeneDecksing
 Browse Tocris compounds for AHCYL1
8 HMDB Compounds for AHCYL1 About this table
2 Novoseek chemical compound relationships for AHCYL1 gene About this table
Search CenterWatch for drugs/clinical trials and news about AHCYL1 / SAHH2
|
Transcripts
for AHCYL1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for AHCYL1 gene (5 alternative transcripts): NM_001242673.1 NM_001242674.1 NM_001242675.1 NM_001242676.1 NM_006621.5 Unigene Cluster for AHCYL1: Adenosylhomocysteinase-like 1 Hs.743973 [show with all ESTs]Unigene Representative Sequence: NM_0012426736 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000369799(uc001dyx.3 uc010ovw.2 uc021ork.1 uc010ovx.2 uc001dyy.3)
ENST00000475081 ENST00000359172 ENST00000481423 ENST00000469401 ENST00000393614
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for AHCYL1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for AHCYL1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: AHCYL1 (NM_006621) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for AHCYL1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AHCYL1 |
Additional cDNA sequence: AF035319.1 AF315687.1 AK131563.1 AK303690.1 AK308080.1 AK313392.1 AK316110.1 AL049954.1 BC003631.2 BC007576.1 BC010681.1 BC016942.1 BC065254.1 BC095476.1 BC110896.1 BC111563.1 U82761.1 24/29 DOTS entries (see all 29): DT.101958184 DT.100057235 DT.97789848 DT.40304277 DT.97813917 DT.65288385 DT.121375881 DT.100877001 DT.100876993 DT.92066102 DT.100876997 DT.100059706 DT.100688028 DT.100722270 DT.121375909 DT.92456971 DT.100703874 DT.100877002 DT.100877004 DT.121375930 DT.92456959 DT.100876992 DT.100877007 DT.102834566 24/696 AceView cDNA sequences (see all 696): CD623006 CR606586 CB143118 AW130150 AW615220 AI870416 BQ772895 BF196621 BQ008370 BQ021256 BX115601 AA432168 CA867482 AA887552 AI474302 AA688398 AA905548 AA507003 BU192401 CB140553 BQ020652 BU072834 AL527928 AA206817
GeneLoc Exon Structure
5/14 Alternative Splicing Database (ASD) splice patterns (SP) for AHCYL1 (see all 14) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c | · | 8d | ^ | 9a | · | 9b | · | 9c | ^ | 10a | · | 10b | · | 10c | ^ | 11a | · | 11b | · | 11c | ^ | 12 | ^ | 13 | ^ |
|---|
|
| SP1: | | | | | | | - | | - | | - | | - | | - | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | - | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | - | | | | | | | | | | |
| SP4: | | | | | | | - | | - | | - | | - | | - | | | | | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | - | | | | - | | - | | - | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 14a | · | 14b | ^ | 15a | · | 15b | ^ | 16 | ^ | 17 | ^ | 18a | · | 18b | ^ | 19a | · | 19b | · | 19c | ^ | 20 | ^ | 21a | · | 21b |
|---|
|
| SP1: | | | | | | | | | | | | | - | | | | | | - | | - | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for AHCYL1
|
Expression
for AHCYL1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| AHCYL1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGGAGAGCAA
About this image
See AHCYL1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for AHCYL1
SOURCE GeneReport for Unigene cluster: Hs.743973
UniProtKB/Swiss-Prot: SAHH2_HUMAN, O43865Tissue specificity: Expressed in dendritic cells
SABiosciences Custom PCR Arrays for AHCYL1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for AHCYL1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat AHCYL1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat AHCYL1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AHCYL1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AHCYL1 |
Orthologs
for AHCYL1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for AHCYL1 gene from 7/29 species (see all 29) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
AHCYL11 |
adenosylhomocysteinase-like 1 |
84.05(n)
96.32(a) |
|
419803 NM_001030913.1 NP_001026084.1 |
lizard
(Anolis carolinensis) |
Reptilia |
AHCYL16AHCY6 |
-- |
96(a)51(a) |
1 ↔ 1possible ortholog |
4(106293083-106310777) 4(138042257-138060141) |
zebrafish
(Danio rerio) |
Actinopterygii |
ahcyl11 |
S-adenosylhomocysteine hydrolase-like 1 |
79.02(n)
92.43(a) |
|
798918 NM_201293.1 NP_958450.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG99773
Ahcy89E1 |
adenosylhomocysteinase3
Adenosylhomocysteinase 89E1 |
78(a)
(best of 2)3
67.17(n)1
71.03(a)1 |
|
62F33
420431 NM_206500.11 NP_996222.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
ahcy-16 |
Adenosylhomocysteinase |
51(a) |
possible ortholog |
I(6836389-6838141) |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
HOG16SAHH26 |
adenosylhomocysteinase 2 |
44(a)44(a) |
possible orthologpossible ortholog |
4(8054861-8057181) 3(8587664-8589713) |
rice
(Oryza sativa) |
Liliopsida |
-- |
erythronate-4-phosphate dehydrogenase, putative, e... |
45(a) |
possible ortholog |
11(14956262-14959287) |
ENSEMBL Gene Tree for AHCYL1 (if available)
TreeFam Gene Tree for AHCYL1 (if available) |
Paralogs
for AHCYL1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for AHCYL1 gene
- AHCY2 AHCYL22
2 SIMAP similar genes for AHCYL1 using alignment to 4 protein entries: SAHH2_HUMAN (see all proteins):AHCYL2 AHCY
AHCYL1 for paralogs About GeneDecksing
|
Genomic Variants
for AHCYL1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for AHCYL1 (110527308 - 110566364 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for AHCYL1: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing AHCYL1 |
|
Disorders
/ Diseases
for AHCYL1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
AHCYL1 for disorders About GeneDecksing
OMIM gene information: 607826
OMIM disorders: --
12  diseases for AHCYL1: About MalaCardshomocysteine xeroderma pigmentosum cystic fibrosis tonsillitis
aldosteronism fibrosis colon carcinoma osteosarcoma
tuberculosis carcinoma malaria mycobacterium tuberculosis
Export disorders for AHCYL1 gene to outside databases
|
Publications
for AHCYL1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for AHCYL1 gene, integrated from 9 sources (see all 49):
(articles sorted by number of sources associating them with AHCYL1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Suppression and overexpression of adenosylhomocysteine hydrolase-like protein 1 (AHCYL1) influences zebrafish embryo development: a possible role for AHCYL1 in inositol phospholipid signaling. (PubMed id 16754674)1, 2, 3, 9 Cooper B.J....Kato M. (2006)
- Identification of an S-adenosylhomocysteine hydrolase-like transcript induced during dendritic cell differentiation. (PubMed id 11904675)1, 2, 3 Dekker J.W.... Kato M. (2002)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Redifferentiation of dedifferentiated chondrocytes and chondrogenesis of human bone marrow stromal cells via chondrosphere formation with expression profiling by large-scale cDNA analysis. (PubMed id 12878157)1, 2 Imabayashi H.... Umezawa A. (2003)
- IRBIT, a novel inositol 1,4,5-trisphosphate (IP3) receptor-binding protein, is released from the IP3 receptor upon IP3 binding to the receptor. (PubMed id 12525476)1, 3 Ando H....Mikoshiba K. (2003)
- Characterization of a large population of mRNAs from human testis. (PubMed id 7782076)1, 2 Pawlak A....Guellaen G. (1995)
- Paradoxical expression of AHCYL1 affecting ovarian car cinogenesis between chickens and women. (PubMed id 22826361)1 Jeong W....Song G. (2012)
- Relief of autoinhibition of the electrogenic Na-HCO(3) [corrected] cotransporter NBCe1-B: role of IRBIT vs.amino-terminal truncation. (PubMed id 22012331)1 Lee S.K....Parker M.D. (2012)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
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External Searches for AHCYL1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
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Genome Databases showing AHCYL1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing AHCYL1 gene
(According to HUGE)
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Specialized Databases showing AHCYL1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Name | Description |
| PharmGKB entry for AHCYL1 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for AHCYL1 gene:
Search GeneIP for patents involving AHCYL1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for AHCYL1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for AHCYL1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for AHCYL1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for AHCYL1 | | | OriGene Protein Over-expression Lysate for AHCYL1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for AHCYL1 | | OriGene 3'-UTR Clone for AHCYL1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for AHCYL1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for AHCYL1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for AHCYL1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for AHCYL1 | | OriGene Custom Protein Services for AHCYL1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat AHCYL1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing AHCYL1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AHCYL1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat AHCYL1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AHCYL1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat AHCYL1 |
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| | | | Search Tocris compounds for AHCYL1 |
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 | | | AHCYL1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AHCYL1 |
|  |  |  | | | | Search ThermoFisher Antibodies for AHCYL1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AHCYL1 |
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