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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

AHCTF1 Gene

protein-coding   GIFtS: 50
GCID: GC01M247002

AT Hook Containing Transcription Factor 1

  Search for AHCTF1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
AT Hook Containing Transcription Factor 11 2     TMBS622 3
ELYS2 3 5     MST1082
ELYS Transcription Factor Like Protein TMBS621 2     ELYS Transcription Factor-Like Protein TMBS622
Embryonic Large Molecule Derived From Yolk Sac2 3     Protein ELYS2
Putative AT-Hook-Containing Transcription Factor 12 3     Protein MEL-283

External Ids:    HGNC: 246181   Entrez Gene: 259092   Ensembl: ENSG000001532077   OMIM: 6108535   UniProtKB: Q8WYP53   

Export aliases for AHCTF1 gene to outside databases

Previous GC identifers: GC01M243329 GC01M245069 GC01M217396


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for AHCTF1 Gene: 
AHCTF1 (AT hook containing transcription factor 1) is a protein-coding gene. Among its related super-pathways are Mitotic Anaphase and Mitotic Prometaphase. GO annotations related to this gene include DNA binding and sequence-specific DNA binding transcription factor activity.

UniProtKB/Swiss-Prot: ELYS_HUMAN, Q8WYP5
Function: Required for the assembly of a functional nuclear pore complex (NPC) on the surface of chromosomes as
nuclei form at the end of mitosis. May initiate NPC assembly by binding to chromatin and recruiting the
Nup107-160 subcomplex of the NPC. Also required for the localization of the Nup107-160 subcomplex of the NPC to
the kinetochore during mitosis and for the completion of cytokinesis

Gene Wiki entry for AHCTF1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.2  NT_167186.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the AHCTF1 gene promoter:
         AML1a   XBP-1   RelA   AP-4   POU3F2   NF-kappaB   HNF-1A   Egr-2   HSF2   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidAHCTF1 promoter sequence
   Search SABiosciences Chromatin IP Primers for AHCTF1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AHCTF1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q44   Ensembl cytogenetic band:  1q44   HGNC cytogenetic band: 1q44

AHCTF1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AHCTF1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M247002:  view genomic region     (about GC identifiers)

Start:
247,002,400 bp from pter      End:
247,095,280 bp from pter
Size:
92,881 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ELYS_HUMAN, Q8WYP5 (See protein sequence)
Recommended Name: Protein ELYS  
Size: 2266 amino acids; 252498 Da
Subunit: Associates with the Nup107-160 subcomplex of the NPC
Subcellular location: Cytoplasm (By similarity). Nucleus matrix (By similarity). Chromosome, centromere,
kinetochore. Nucleus, nucleoplasm. Nucleus, nuclear pore complex. Note=Localizes to the nuclear pore complex
(NPC) throughout interphase. Localizes to the kinetochore from prophase, and this appears to require the
Nup107-160 subcomplex of the NPC. Localizes to the periphery of chromatin from late anaphase
Sequence caution: Sequence=AAN65622.1; Type=Frameshift; Positions=Several; Sequence=AAQ13621.1; Type=Erroneous
initiation; Note=Translation N-terminally extended; Sequence=BAB78516.1; Type=Erroneous initiation;
Note=Translation N-terminally extended;
Secondary accessions: A6NGM0 A8MSG9 A8MZ86 Q7Z4E3 Q8IZA4 Q96EH9 Q9Y4Q6
Alternative splicing: 3 isoforms:  Q8WYP5-1   Q8WYP5-2   Q8WYP5-3   

Explore the universe of human proteins at neXtProt for AHCTF1: NX_Q8WYP5

Explore proteomics data for AHCTF1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8WYP5

  • AHCTF1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    AHCTF1 Protein Expression
    REFSEQ proteins: NP_056261.4  
    ENSEMBL proteins: 
     ENSP00000355464   ENSP00000355465   ENSP00000418007   ENSP00000417115   ENSP00000375705  
    Reactome Protein details: Q8WYP5
    Human Recombinant Protein Products for AHCTF1: 
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    Cloud-Clone Corp. Proteins for AHCTF1 

    Gene Ontology (GO): 5/10 cellular component terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000777colocalizes with condensed chromosome kinetochore IDA17098863
    GO:0000785colocalizes with chromatin IDA17098863
    GO:0005634nucleus IDA--
    GO:0005643colocalizes with nuclear pore IDA17098863
    GO:0005654nucleoplasm IEA--

    AHCTF1 for ontologies           About GeneDecksing



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    LSBio Antibodies in human, mouse, rat for AHCTF1 

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR017956 AT_hook_DNA-bd_motif
     IPR025151 ELYS_dom

    Graphical View of Domain Structure for InterPro Entry Q8WYP5

    ProtoNet protein and cluster: Q8WYP5

    UniProtKB/Swiss-Prot: ELYS_HUMAN, Q8WYP5
    Similarity: Belongs to the ELYS family
    Similarity: Contains 1 A.T hook DNA-binding domain


    AHCTF1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ELYS_HUMAN, Q8WYP5
    Function: Required for the assembly of a functional nuclear pore complex (NPC) on the surface of chromosomes as
    nuclei form at the end of mitosis. May initiate NPC assembly by binding to chromatin and recruiting the
    Nup107-160 subcomplex of the NPC. Also required for the localization of the Nup107-160 subcomplex of the NPC to
    the kinetochore during mitosis and for the completion of cytokinesis

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
         
    AHCTF1 for ontologies           About GeneDecksing


    Phenotypes:
         8 GenomeRNAi human phenotypes for AHCTF1:
     Decreased NANOG protein expres  Decreased OCT4 protein express  Decreased POU5F1-GFP protein e  Decreased TP53 protein express 
     Decreased viability of wild-ty  Increased gamma-H2AX phosphory  Synthetic lethal with Ras  Synthetic lethal with c-Myc af 

         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Ahctf1):
     cellular  embryogenesis  mortality/aging 

    AHCTF1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Ahctf1tm1Taga for AHCTF1

       inGenious Targeting Laboratory - Custom generated mouse model solutions for AHCTF1 
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    SwitchGear 3'UTR luciferase reporter plasmidAHCTF1 3' UTR sequence
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for AHCTF1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1M Phase
    Mitotic Anaphase0.94
    M Phase0.88
    Separation of Sister Chromatids0.94
    Mitotic M-M/G1 phases0.88
    Mitotic Metaphase and Anaphase0.94
    2Resolution of Sister Chromatid Cohesion
    Resolution of Sister Chromatid Cohesion0.93
    Mitotic Prometaphase0.93
    3Cell Cycle
    Cell Cycle, Mitotic0.84
    Cell Cycle0.84
    4Gastric cancer network 2
    Gastric cancer network 2

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 BioSystems Pathway for AHCTF1
        Gastric cancer network 2

    5/9        Reactome Pathways for AHCTF1 (see all 9)
        Mitotic Metaphase and Anaphase
    Mitotic Prometaphase
    Resolution of Sister Chromatid Cohesion
    Mitotic Anaphase
    Cell Cycle



    AHCTF1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for AHCTF1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/84 Interacting proteins for AHCTF1 (Q8WYP52, 3 ENSP000003757054) via UniProtKB, MINT, STRING, and/or I2D (see all 84)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NUP107P577402, 3, ENSP000002291794MINT-4301709 MINT-4301750 MINT-4301632 MINT-4301665 I2D: score=1 STRING: ENSP00000229179
    KPNB1Q149742, 3, ENSP000002901584MINT-4301643 I2D: score=1 STRING: ENSP00000290158
    NUP160Q127692, 3, ENSP000003677214MINT-4301654 MINT-4301750 MINT-4301592 I2D: score=1 STRING: ENSP00000367721
    NUP62P371982, 3, ENSP000003055034MINT-4301750 MINT-4301693 I2D: score=1 STRING: ENSP00000305503
    NUP133Q8WUM02, 3, ENSP000002613964MINT-4301609 I2D: score=1 STRING: ENSP00000261396
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000278mitotic cell cycle TAS--
    GO:0000910cytokinesis IMP17098863
    GO:0006355regulation of transcription, DNA-dependent ----
    GO:0015031protein transport IEA--
    GO:0051028mRNA transport IEA--

    AHCTF1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for AHCTF1 (ELYS)

    Search CenterWatch for drugs/clinical trials and news about AHCTF1 / ELYS

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for AHCTF1 gene: 
    NM_015446.4  

    Unigene Cluster for AHCTF1:

    AT hook containing transcription factor 1
    Hs.300887  [show with all ESTs]
    Unigene Representative Sequence: NM_015446
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000470300(uc001ibw.1 uc009xgs.1) ENST00000366508 ENST00000326225(uc001ibv.2)
    ENST00000498601 ENST00000483900 ENST00000477526 ENST00000478568 ENST00000391829

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    8/33 QIAGEN miScript miRNA Assays for microRNAs that regulate AHCTF1 (see all 33):
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    SwitchGear 3'UTR luciferase reporter plasmidAHCTF1 3' UTR sequence
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    Additional mRNA sequence: 

    AB059277.1 AF173978.1 AK091364.1 AK091510.1 AK095398.1 AK122844.1 AL080144.1 AL832213.1 
    AL833491.1 AY157619.1 BC012307.1 BC030564.1 BC047361.1 

    17 DOTS entries:

    DT.100722077  DT.455576  DT.100782662  DT.121003283  DT.91754159  DT.100782663  DT.121003264  DT.213897 
    DT.213896  DT.91768609  DT.100735543  DT.100782664  DT.100782665  DT.100782667  DT.121421286  DT.92045421 
    DT.95270397 

    24/208 AceView cDNA sequences (see all 208):

    AA635850 BU618907 BU145624 BC047361 AA434605 AA748759 AL041058 AW630710 
    AX746937 AA633977 BC012307 BE886672 BM711248 AK091364 BU728031 CB160934 
    AV703690 AA761156 AK095398 AL522811 BM467863 AI374620 CA426785 BC030564 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for AHCTF1 (see all 6)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22a · 22b
    SP1:                                                                    -                                         -                                       
    SP2:                                                                    -                                                                                 
    SP3:                                                                                                                                                      
    SP4:                                                                                                                                                      
    SP5:                                                                                                                                                      


    ECgene alternative splicing isoforms for AHCTF1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    AHCTF1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GATGCAACGT
    AHCTF1 Expression
    About this image


    See AHCTF1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for AHCTF1

    SOURCE GeneReport for Unigene cluster: Hs.300887
        SABiosciences Custom PCR Arrays for AHCTF1
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AHCTF1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for AHCTF1 gene from 6/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ahctf11 , 5 AT hook containing transcription factor 11, 5 78.63(n)1
    71.89(a)1
      1 (83.62 cM)5
    2267471  NM_026375.21  NP_080651.21 
     1797448945 
    chicken
    (Gallus gallus)
    Aves AHCTF11 AT hook containing transcription factor 1 66.53(n)
    60.32(a)
      421484  NM_001161801.2  NP_001155273.1 
    lizard
    (Anolis carolinensis)
    Reptilia AHCTF16
    Uncharacterized protein
    51(a)
    1 ↔ 1
    1(235667439-235717211)
    African clawed frog
    (Xenopus laevis)
    Amphibia U07608.12   -- 83.42(n)    U07608.1 
    zebrafish
    (Danio rerio)
    Actinopterygii ahctf11 AT hook containing transcription factor 1 60.56(n)
    60.66(a)
      553494  XM_692635.4  XP_697727.4 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG142156
    --
    18(a)
    1 ↔ 1
    X(19546340-19553444)


    ENSEMBL Gene Tree for AHCTF1 (if available)
    TreeFam Gene Tree for AHCTF1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for AHCTF1 gene

    AHCTF1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for AHCTF1
    PGOHUM00000240408


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2141 SNPs in AHCTF1 are shown (see all 2141)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1448632531,2
    C--247001907(+) GAAGT-/GGGCG 
            
    GGGCG
    1 -- int10--------
    rs2018153831,2
    C--247001910(+) CGGGG-/CGGGG 
            
    GGAAG
    1 -- int10--------
    rs1899866941,2
    --247001960(+) AGCCCA/GTTCAG 1 -- int10--------
    rs1162936291,2
    C,F--247001980(+) TTTGCA/GTGTTG 1 -- int11Minor allele frequency- G:0.04WA 118
    rs1483405361,2
    --247001995(+) GTCAAC/GCAAGT 1 -- int10--------
    rs1821051181,2
    --247002059(+) ATCTAA/GGAAGC 1 -- int10--------
    rs1449711331,2
    C--247002128(+) ACTAC-/TATGATA 1 -- int10--------
    rs1412127891,2
    --247002165(+) TACTAC/TGATAC 1 -- int10--------
    rs1494297371,2
    C--247002201(+) TACCT-/TAC   
      TACTGA
    TACTA
    1 -- int10--------
    rs1512697141,2
    C--247002204(+) CTTAC-/TACTGA
            
    TACTA
    1 -- int10--------

    HapMap Linkage Disequilibrium report for AHCTF1 (247002400 - 247095280 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/15 variations for AHCTF1 (see all 15):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv1940734CNV Deletion18987734
    esv2667587CNV Deletion23128226
    esv2665105CNV Deletion23128226
    esv2857CNV Deletion18987735
    esv2727607CNV Deletion23290073
    esv2446831CNV Deletion19546169
    esv2727618CNV Deletion23290073
    nsv509768CNV Insertion20534489
    nsv5276CNV Loss18451855
    nsv511751CNV Loss21212237

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    AHCTF1 for disorders           About MalaCards
    OMIM gene information: 610853    OMIM disorders: --


    AHCTF1 for disorders           About GeneDecksing


    Export disorders for AHCTF1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for AHCTF1 gene, integrated from 9 sources (see all 32):
    (articles sorted by number of sources associating them with AHCTF1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of a novel transcription factor, ELYS, expressed predominantly in mouse foetal haematopoietic tissues. (PubMed id 11952839)1, 2, 3 Kimura N.... Taga T. (2002)
    2. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
    3. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    4. ELYS is a dual nucleoporin/kinetochore protein required for nuclear pore assembly and proper cell division. (PubMed id 17098863)1, 2 Rasala B.A.... Forbes D.J. (2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Molecular basis for Nup37 and ELY5/ELYS recruitment to the nuclear pore complex. (PubMed id 22955883)1 Bilokapic S. and Schwartz T.U. (2012)
    7. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)
    8. The nucleoporin ELYS/Mel28 regulates nuclear envelope subdomain formation in HeLa cells. (PubMed id 22555603)1 Clever M....Imamoto N. (2012)
    9. A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells. (PubMed id 22412018)1 Roux K.J.... Burke B. (2012)
    10. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 25909 HGNC: 24618 AceView: ELYS Ensembl:ENSG00000153207 euGenes: HUgn25909
    ECgene: AHCTF1 H-InvDB: AHCTF1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for AHCTF1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for AHCTF1 gene:
    Search GeneIP for patents involving AHCTF1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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