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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

AGXT2L2 Gene

protein-coding   GIFtS: 49
GCID: GC05M177635

alanine-glyoxylate aminotransferase 2-like 2

 Explore 2 diseases affiliated with
AGXT2L2 via our new
 Human Malady Compendium 
Biological research products
for AGXT2L2
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Alanine-Glyoxylate Aminotransferase 2-Like 21 2     EC 4.2.3.1343
Alanine--Glyoxylate Aminotransferase 2-Like 22 3     EC 2.6.18
MGC158751     EC 2.6.1.118
5-Phosphohydroxy-L-Lysine Phospho-Lyase2     EC 2.6.1.138
PHLU2     EC 2.6.1.448

External Ids:    HGNC: 282491   Entrez Gene: 850072   Ensembl: ENSG000001753097   OMIM: 6146835   UniProtKB: Q8IUZ53   

Export aliases for AGXT2L2 gene to outside databases

Previous GC identifers: GC05M177569 GC05M172361


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: AT2L2_HUMAN, Q8IUZ5
Function: Catalyzes the pyridoxal-phosphate-dependent breakdown of 5-phosphohydroxy-L-lysine, converting it to ammonia,
inorganic phosphate and 2-aminoadipate semialdehyde




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NC_018916.1  NT_023133.13  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the AGXT2L2 gene promoter:
         AML1a   p53   Tal-1beta   HNF-4alpha1   SEF-1 (1)   NF-kappaB1   Zic3   Pax-4a   ITF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidAGXT2L2 promoter sequence
   Search SABiosciences Chromatin IP Primers for AGXT2L2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AGXT2L2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q35.3   Ensembl cytogenetic band:  5q35.3   HGNC cytogenetic band: 5q35.3

AGXT2L2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AGXT2L2 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M177635:  view genomic region     (about GC identifiers)

Start:
177,635,498 bp from pter      End:
177,659,803 bp from pter
Size:
24,306 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: AT2L2_HUMAN, Q8IUZ5 (See protein sequence)
Recommended Name: 5-phosphohydroxy-L-lysine phospho-lyase  
Size: 450 amino acids; 49711 Da
Cofactor: Pyridoxal phosphate
Subunit: Homotetramer (By similarity)
Subcellular location: Mitochondrion (Potential)
Caution: Does not seem to possess aminotransferase activity (PubMed:22241472)
Secondary accessions: B3KN36 D3DWP9 Q8WYS6 Q96HW8
Alternative splicing: 3 isoforms:  Q8IUZ5-1   Q8IUZ5-2   Q8IUZ5-3   

Explore the universe of human proteins at neXtProt for AGXT2L2: NX_Q8IUZ5

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8IUZ5

  • 4 DME Specific Peptides for AGXT2L2 (Q8IUZ5)
     ADEIQVG  GLAVLNV  PDIVTMGK  NSGSEANDLALRLA 

    AGXT2L2 Protein expression data from MOPED and PaxDb:    About this image 
    AGXT2L2 Protein Expression
    REFSEQ proteins: NP_699204.1  
    ENSEMBL proteins: 
     ENSP00000310978   ENSP00000423806   ENSP00000377128   ENSP00000425425   ENSP00000427444  
     ENSP00000424608   ENSP00000321290   ENSP00000421810  

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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for AGXT2L2

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IEA--

    AGXT2L2 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for AGXT2L2


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    AGXT2L2 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR005814 Aminotrans_3
     IPR015424 PyrdxlP-dep_Trfase
     IPR015421 PyrdxlP-dep_Trfase_major_sub1
     IPR015422 PyrdxlP-dep_Trfase_major_sub2

    Graphical View of Domain Structure for InterPro Entry Q8IUZ5

    ProtoNet protein and cluster: Q8IUZ5

    1 Blocks protein family: IPB005814 Aminotransferase class-III

    UniProtKB/Swiss-Prot: AT2L2_HUMAN, Q8IUZ5
    Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: AT2L2_HUMAN, Q8IUZ5
    Function: Catalyzes the pyridoxal-phosphate-dependent breakdown of 5-phosphohydroxy-L-lysine, converting it to ammonia,
    inorganic phosphate and 2-aminoadipate semialdehyde
    Catalytic activity: (5R)-5-phosphonooxy-L-lysine + H(2)O = (S)-2-amino-6-oxohexanoate + NH(3) + phosphate
    Biophysicochemical properties: Kinetic parameters: KM=16 uM for 5-phosphohydroxy-L-lysine (at 30 degrees Celsius);
    Vmax=256 nmol/min/mg enzyme;

         Enzyme Numbers (IUBMB): EC 2.6.1.132 EC 2.6.1.112 EC 2.6.12 EC 2.6.1.442 EC 4.2.3.1341

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity ----
    GO:0008483transaminase activity IEA--
    GO:0016829lyase activity IEA--
    GO:0030170pyridoxal phosphate binding IEA--
         
    AGXT2L2 for ontologies           About GeneDecksing


    Phenotypes:
         5 MGI mutant phenotypes (inferred from 1 allele(MGI details for Agxt2l2):
     behavior/neurological  hematopoietic system  homeostasis/metabolism  immune system  vision/eye 

    AGXT2L2 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for AGXT2L2 

    miRNA
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    Inhib. RNA
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AGXT2L2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for AGXT2L2

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    4 Interacting proteins for AGXT2L2 (Q8IUZ52 ENSP000003109784) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    AGXT2L2Q8IUZ52MINT-68342
    POT1ENSP000003502494STRING: ENSP00000350249
    DMAP1ENSP000003126974STRING: ENSP00000312697
    MRGBPENSP000003595184STRING: ENSP00000359518
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for AGXT2L2

    2 HMDB Compounds for AGXT2L2    About this table
    CompoundSynonyms CAS #PubMed Ids
    L-Alanine(2S)-2-Aminopropanoate (see all 35)56-41-7--
    Pyridoxal 5'-phosphateApolon B6 (see all 27)54-47-7--

    2 DrugBank Compounds for AGXT2L2    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    L-Alanine(2S)-2-Aminopropanoic acid (see all 15)56-41-7target--17139284 17016423
    Pyridoxal PhosphateCodecarboxylase (see all 9)54-47-7targetcofactor17139284 17016423

    Search CenterWatch for drugs/clinical trials and news about AGXT2L2 / AT2L2 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for AGXT2L2 gene (2 alternative transcripts): 
    NM_032921.1  NM_153373.2  

    Unigene Cluster for AGXT2L2:

    Alanine-glyoxylate aminotransferase 2-like 2
    Hs.248746  [show with all ESTs]
    Unigene Representative Sequence: BC037238
    18 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000308158(uc003miz.3 uc003mjb.3) ENST00000481436(uc003miy.3)
    ENST00000481811 ENST00000489262(uc003mjc.3 uc003mja.3) ENST00000474052
    ENST00000393488 ENST00000493197 ENST00000494126 ENST00000510991 ENST00000476487(uc003mjd.1)
    ENST00000506045 ENST00000510913 ENST00000504096 ENST00000514424 ENST00000323594
    ENST00000506001 ENST00000511716 ENST00000476170

    miRNA
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    Inhib. RNA
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    Additional cDNA sequence: 

    AK023470.1 AK090397.1 AK292061.1 BC008009.1 BC028002.1 BC037238.1 BC037567.1 BC039012.1 
    BC067745.1 BC110335.1 

    24/32 DOTS entries (see all 32):

    DT.100784754  DT.95164313  DT.443937  DT.120839447  DT.100784760  DT.95162645  DT.40287340  DT.95322565 
    DT.75102862  DT.100784753  DT.95184703  DT.100812914  DT.120839526  DT.101988022  DT.97790815  DT.100026091 
    DT.100026092  DT.120839420  DT.95322925  DT.100000580  DT.100766339  DT.120839454  DT.120839504  DT.120839608 

    24/359 AceView cDNA sequences (see all 359):

    AI139923 BE302486 AA961029 BU553838 AI360080 AI636931 BM021909 AU121648 
    AA381743 AA936199 AI124861 BM769982 BC037567 BX115530 BC067745 AI625193 
    AA281997 AI281829 AK023470 AA381857 BM694452 BG150769 AI866264 AI700023 

    GeneLoc Exon Structure

    5/18 Alternative Splicing Database (ASD) splice patterns (SP) for AGXT2L2 (see all 18)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c · 4d ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b · 7c · 7d ^ 8a · 8b · 8c ^ 9 ^ 10a · 10b ^ 11a · 11b ·
    SP1:                    -     -           -                       -     -     -                       -     -                 -     -                           
    SP2:                                                                                                                                                  -         
    SP3:                                                              -     -     -                       -     -                 -     -                 -         
    SP4:                                                                                                  -     -                 -     -                           
    SP5:                                                                                                  -     -                 -     -                 -         

    ExUns: 11c · 11d ^ 12a · 12b · 12c ^ 13 ^ 14a · 14b ^ 15 ^ 16
    SP1:                                                            
    SP2:              -     -     -                                 
    SP3:                                                            
    SP4:                                                            
    SP5:                                                            


    ECgene alternative splicing isoforms for AGXT2L2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    AGXT2L2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CACACCCATT
    AGXT2L2 Expression
    About this image
    See AGXT2L2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for AGXT2L2

    SOURCE GeneReport for Unigene cluster: Hs.248746
        SABiosciences Custom PCR Arrays for AGXT2L2

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AGXT2L2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the last universal common ancestor (LUCA).

    Orthologs for AGXT2L2 gene from 9/24 species (see all 24)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Agxt2l21 , 5 alanine-glyoxylate aminotransferase 2-like 21, 5 86.04(n)1
    87.08(a)1
      11 (31.08 cM)5
    729471  NM_028398.21  NP_082674.11 
     515847575 
    chicken
    (Gallus gallus)
    Aves AGXT2L21 alanine-glyoxylate aminotransferase 2-like 2 70.24(n)
    76.54(a)
      416374  XM_414688.3  XP_414688.3 
    lizard
    (Anolis carolinensis)
    Reptilia AGXT2L26
    --
    73(a)
    1 ↔ 1
    2(142021759-142034888)
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1230071 zgc:123007 65.91(n)
    67.81(a)
      557205  NM_001037557.1  NP_001032646.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG87456
    --
    45(a)
    1 → many
    3L(13853127-13860005)
    worm
    (Caenorhabditis elegans)
    Secernentea T01B11.26
    Alanine--glyoxylate aminotransferase 2-like
    44(a)
    possible ortholog
    IV(8449336-8451758)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons GSA16
    GSA26
    glutamate-1-semialdehyde 2,1-aminomutase 2
    15(a)
    15(a)
    possible ortholog
    possible ortholog
    5(25451875-25453841)
    3(18049614-18051702)
    rice
    (Oryza sativa)
    Liliopsida Os.158302 Oryza sativa alanineglyoxylate aminotransferase-like more 71.71(n)    AK060423.1 
    E. coli
    (Escherichia coli)
    Gamma proteobacteria hemL6
    glutamate-1-semialdehyde aminotransferase (aminomu...
    19(a)
    possible ortholog
    Chromosome(173602-174882)


    ENSEMBL Gene Tree for AGXT2L2 (if available)
    TreeFam Gene Tree for AGXT2L2 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for AGXT2L2 gene
    AGXT22  AGXT2L12  
    3 SIMAP similar genes for AGXT2L2 using alignment to 8 protein entries:     AT2L2_HUMAN (see all proteins):
    FLJ00272    AGXT2L1    AGXT2

    AGXT2L2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/495 NCBI SNPs in AGXT2L2 are shown (see all 495    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1837149761,2
    --177638716(+) CATCAA/GGTGCA 1 -- int10--------
    rs1152090541,2
    F--177638820(+) CTTGCC/TGAGGC 1 -- int11Minor allele frequency- T:0.03WA 118
    rs1173578721,2
    F--177638860(+) GTGCAT/ACTTCA 1 -- int11Minor allele frequency- A:0.03EA 120
    rs1181267891,2
    C,F--177638878(+) GAAGCA/TAGGCC 1 -- int11Minor allele frequency- T:0.03EA 120
    rs1892531921,2
    C--177638886(+) GCCCAC/TTCACC 1 -- int10--------
    rs743985091,2
    C,F--177638888(+) CCACTC/GACCTG 1 -- int11Minor allele frequency- G:0.02WA 118
    rs1817734521,2
    C--177638902(+) TACACC/TTAGGC 1 -- ut310--------
    rs1504969891,2
    C--177638915(+) AGCAGA/GGCTGG 1 -- ut310--------
    rs2019107421,2
    --177638927(+) TTAGGA/GCTGGA 2 P S mis10--------
    rs2008242801,2
    --177638932(+) GCTGGA/CGCCTC 2 R L mis10--------

    HapMap Linkage Disequilibrium report for AGXT2L2 (177635498 - 177659803 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for AGXT2L2: --

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    AGXT2L2 for disorders           About GeneDecksing

    OMIM gene information: 614683    OMIM disorders: --

    2 diseases for AGXT2L2:    About MalaCards
    tuberculosis    mycobacterium tuberculosis

    Human Genome Epidemiology (HuGE) Navigator: AGXT2L2 (1 document)

    Export disorders for AGXT2L2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for AGXT2L2 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with AGXT2L2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    3. Molecular identification of hydroxylysine kinase and o f ammoniophospholyases acting on 5-phosphohydroxy-L-lysine and phosphoethanolami ne. (PubMed id 22241472)2 Veiga-da-Cunha M....Van Schaftingen E. (2012)
    4. Genome-wide YFP fluorescence complementation screen id entifies new regulators for telomere signaling in human cells. (PubMed id 21044950)1 Lee O.H....Songyang Z. (2011)
    5. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1 Hendrickson S.L....O'Brien S.J. (2010)
    6. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
    7. Drugs, their targets and the nature and number of dru g targets. (PubMed id 17016423)7 Imming P....Meyer A. (2006)
    8. How many drug targets are there? (PubMed id 17139284)7 Overington J.P....Hopkins A.L. (2006)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    10. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 85007 HGNC: 28249 AceView: MGC15875 Ensembl:ENSG00000175309 euGenes: HUgn85007
    ECgene: AGXT2L2 H-InvDB: AGXT2L2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for AGXT2L2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for AGXT2L2 gene:
    Search GeneIP for patents involving AGXT2L2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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