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AGTPBP1 Gene

protein-coding   GIFtS: 57
GCID: GC09M088161

ATP/GTP Binding Protein 1

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
ATP/GTP Binding Protein 11 2     Tyrosine Carboxypeptidase1 2
CCP12 3 5     Nervous System Nuclear Protein Induced By Axotomy Protein 1 Homolog2 3
NNA12 3 5     ATP/GTP-Binding Protein 12 3
carboxypeptidase-tubulin1 2     KIAA10353 5
Cytosolic Carboxypeptidase 11 2     EC 3.4.17.-3
Soluble Carboxypeptidase1 2     EC 3.4.178
Tubulinyl-Tyr Carboxypeptidase1 2     

External Ids:    HGNC: 172581   Entrez Gene: 232872   Ensembl: ENSG000001350497   OMIM: 6068305   UniProtKB: Q9UPW53   

Export aliases for AGTPBP1 gene to outside databases

Previous GC identifers: GC09M079205 GC09M080014 GC09M081716 GC09M083618 GC09M085391 GC09M087351 GC09M057985


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for AGTPBP1 Gene:
NNA1 is a zinc carboxypeptidase that contains nuclear localization signals and an ATP/GTP-binding motif that was
initially cloned from regenerating spinal cord neurons of the mouse.(supplied by OMIM, Jul 2002)

GeneCards Summary for AGTPBP1 Gene:
AGTPBP1 (ATP/GTP binding protein 1) is a protein-coding gene. GO annotations related to this gene include metallocarboxypeptidase activity and tubulin binding. An important paralog of this gene is AGBL5.

UniProtKB/Swiss-Prot: CBPC1_HUMAN, Q9UPW5
Function: Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation
of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also
removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a
long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the
branching point glutamate, a process catalyzed by AGBL5/CCP5 (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the AGTPBP1 gene promoter:
         Pbx1a   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   POU3F2   MEF-2A   FOXJ2 (long isoform)   FOXJ2   aMEF-2   Pax-4a   En-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): AGTPBP1 promoter sequence
   Search Chromatin IP Primers for AGTPBP1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat AGTPBP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q21.33   Ensembl cytogenetic band:  9q21.33   HGNC cytogenetic band: 9q21.33

AGTPBP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AGTPBP1 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M088161:  view genomic region     (about GC identifiers)

Start:
88,161,454 bp from pter      End:
88,356,944 bp from pter
Size:
195,491 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CBPC1_HUMAN, Q9UPW5 (See protein sequence)
Recommended Name: Cytosolic carboxypeptidase 1  
Size: 1226 amino acids; 138448 Da
Cofactor: Binds 1 zinc ion per subunit (By similarity)
Subunit: Interacts with MYLK (By similarity)
Sequence caution: Sequence=BAA82987.2; Type=Frameshift; Positions=10; Sequence=BAB14100.1; Type=Erroneous
initiation; Note=Translation N-terminally extended; Sequence=BAB14505.1; Type=Erroneous initiation;
Note=Translation N-terminally extended; Sequence=BAG61460.1; Type=Erroneous initiation; Note=Translation
N-terminally extended; Sequence=CAH56222.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=EAW62697.1; Type=Erroneous gene model prediction;
Secondary accessions: B4DIT6 B4DRZ8 Q5VV80 Q63HM7 Q658P5 Q6P9D6 Q9H8U6 Q9H9W8 Q9NVK1
Alternative splicing: 3 isoforms:  Q9UPW5-1   Q9UPW5-2   Q9UPW5-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for AGTPBP1: NX_Q9UPW5

Explore proteomics data for AGTPBP1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys44
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for AGTPBP1 (Q9UPW5) (see all 14)
     MYSVQEA  ICYYKNH  ARVHPGE  KFGVKAR 


    See AGTPBP1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001273644.1  NP_001273646.1  NP_056054.2  

    ENSEMBL proteins: 
     ENSP00000365251   ENSP00000349592   ENSP00000365249   ENSP00000365248   ENSP00000365277  
     ENSP00000402804   ENSP00000338512  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR011989 ARM-like
     IPR000834 Peptidase_M14
     IPR016024 ARM-type_fold

    Graphical View of Domain Structure for InterPro Entry Q9UPW5

    ProtoNet protein and cluster: Q9UPW5

    UniProtKB/Swiss-Prot: CBPC1_HUMAN, Q9UPW5
    Similarity: Belongs to the peptidase M14 family


    Find genes that share domains with AGTPBP1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CBPC1_HUMAN, Q9UPW5
    Function: Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation
    of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also
    removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a
    long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the
    branching point glutamate, a process catalyzed by AGBL5/CCP5 (By similarity)

         Enzyme Numbers (IUBMB): EC 3.4.172 EC 3.4.17.-1

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004181metallocarboxypeptidase activity ISS--
    GO:0005488binding ----
    GO:0005515protein binding ----
    GO:0008270zinc ion binding IEA--
    GO:0015631tubulin binding ISS--
         
    Find genes that share ontologies with AGTPBP1           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for AGTPBP1:
     Decreased cilium length  Decreased cilium length after  

         8 MGI mutant phenotypes (inferred from 11 alleles(MGI details for Agtpbp1):
     behavior/neurological  endocrine/exocrine gland  growth/size/body  hearing/vestibular/ear  muscle 
     nervous system  reproductive system  vision/eye 

    Find genes that share phenotypes with AGTPBP1           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for AGTPBP1
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for AGTPBP1
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    hsa-mir-32-5p (MIRT028252), hsa-mir-375 (MIRT019782)

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    1 qRT-PCR Assays for microRNA that regulate AGTPBP1:
    hsa-miR-1305
    SwitchGear 3'UTR luciferase reporter plasmidAGTPBP1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat AGTPBP1

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    Sino Biological Human cDNA Clone for AGTPBP1
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AGTPBP1

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CBPC1_HUMAN, Q9UPW5: Cytoplasm, cytosol (By similarity). Nucleus (By similarity). Mitochondrion (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol4
    mitochondrion4
    nucleus2
    extracellular1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm ----
    GO:0005739mitochondrion ISS--
    GO:0005829cytosol ISS--

    Find genes that share ontologies with AGTPBP1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for AGTPBP1 About    
    See pathways by source

    SuperPathContained pathways About
    1Neuroscience
    Neuroscience


    Find genes that share SuperPaths with AGTPBP1           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Cell Signaling Technology (CST) Pathway for AGTPBP1
        Neuroscience



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for AGTPBP1
    Interactions:

        Search GeneGlobe Interaction Network for AGTPBP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    Selected Interacting proteins for AGTPBP1 (Q9UPW52, 3 ENSP000003385124) via UniProtKB, MINT, STRING, and/or I2D (see all 12)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NYNRINQ9P2P12, 3, ENSP000003719944MINT-2875141 I2D: score=3 STRING: ENSP00000371994
    CBY1Q9Y3M22, 3, ENSP000002160294MINT-2871559 MINT-2871578 I2D: score=3 STRING: ENSP00000216029
    PPFIA1Q131362, 3, ENSP000002539254MINT-2865301 MINT-2865282 I2D: score=3 STRING: ENSP00000253925
    PPFIA4O753352, 3, ENSP000002721984MINT-2865244 MINT-2865263 I2D: score=3 STRING: ENSP00000272198
    ENO1P067332, 3, ENSP000002345904MINT-2858506 I2D: score=3 STRING: ENSP00000234590
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    Gene Ontology (GO): Selected biological process terms (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001754eye photoreceptor cell differentiation ISS--
    GO:0006508proteolysis ----
    GO:0007005mitochondrion organization ISS--
    GO:0007628adult walking behavior IEA--
    GO:0021549cerebellum development ----

    Find genes that share ontologies with AGTPBP1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for AGTPBP1 (CBPC1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for AGTPBP1 gene (3 alternative transcripts): 
    NM_001286715.1  NM_001286717.1  NM_015239.2  

    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000376083 ENST00000357081(uc011ltc.2 uc011ltd.2) ENST00000489265
    ENST00000376081 ENST00000491784 ENST00000376080 ENST00000376109 ENST00000432218
    ENST00000337006(uc004aod.4 uc010mqc.3 uc011lte.2)
    miRNA
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    1 qRT-PCR Assays for microRNA that regulate AGTPBP1:
    hsa-miR-1305
    SwitchGear 3'UTR luciferase reporter plasmidAGTPBP1 3' UTR sequence
    Inhib. RNA
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      QuantiTect SYBR Green Assays in human, mouse, rat AGTPBP1
      QuantiFast Probe-based Assays in human, mouse, rat AGTPBP1

    Selected AceView cDNA sequences (see all 118):

    AW075786 AL833359 AK094726 AA489406 BC060815 AA748736 AL597061 BX100991 
    AW272859 BU195660 CA449535 F04946 AJ430445 AW953115 BM478004 AA629734 
    BX648366 AB028958 BM458596 Z39021 AI205019 BQ006802 AU130004 BQ446713 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for AGTPBP1    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13a · 13b ^ 14a · 14b ^ 15a · 15b ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^
    SP1:        -                                                                 -           -           -                                                         
    SP2:        -                                                                             -           -                                                         
    SP3:                                                                                                                                                            
    SP4:                                                                                                  -                                                         
    SP5:                                                                                                                                                            

    ExUns: 22 ^ 23 ^ 24 ^ 25 ^ 26 ^ 27a · 27b
    SP1:                                          
    SP2:                                          
    SP3:                                          
    SP4:                                          
    SP5:                                          


    ECgene alternative splicing isoforms for AGTPBP1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    AGTPBP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTAACTATTG
    AGTPBP1 Expression
    About this image


    AGTPBP1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Brain (Nervous System)
             Cerebellum
     
     Testis (Reproductive System)
    AGTPBP1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    AGTPBP1 Protein Expression
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AGTPBP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for AGTPBP1 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Agtpbp11 , 5 ATP/GTP binding protein 11, 5 85.22(n)1
    91.36(a)1
      13 (31.87 cM)5
    672691  NM_023328.31  NP_075817.21 
     594495375 
    chicken
    (Gallus gallus)
    Aves AGTPBP11 ATP/GTP binding protein 1 76.45(n)
    79.16(a)
      427460  XM_001233246.3  XP_001233247.3 
    lizard
    (Anolis carolinensis)
    Reptilia AGTPBP16
    ATP/GTP binding protein 1
    77(a)
    1 ↔ 1
    2(41922399-41939905)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.197502 Xenopus laevis transcribed sequence with moderate similarity more 79.32(n)    BJ059872.1 
    zebrafish
    (Danio rerio)
    Actinopterygii agtpbp11 ATP/GTP binding protein 1 65.75(n)
    69.86(a)
      554164  NM_001024445.2  NP_001019616.1 
    worm
    (Caenorhabditis elegans)
    Secernentea F56H1.53   -- 42(a)
    (best of 2)
      I(5762736-5770504)   --


    ENSEMBL Gene Tree for AGTPBP1 (if available)
    TreeFam Gene Tree for AGTPBP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for AGTPBP1 gene
    AGBL52  AGBL12  AGBL42  AGBL22  AGBL32  
    2 SIMAP similar genes for AGTPBP1 using alignment to 4 protein entries:     CBPC1_HUMAN (see all proteins):
    AGBL1    AGBL4

    Find genes that share paralogs with AGTPBP1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for AGTPBP1 (see all 3752)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0368844
    A colorectal cancer sample4--see VAR_0368842 E K mis40--------
    rs345424311,2
    C--88144547(+) TTTTT-/C/TCTTGC 1 -- int11NA 2
    rs751507541,2
    C,F--88161191(+) GAAACC/TCACCA 1 -- int11Minor allele frequency- T:0.50WA 2
    rs70479611,2
    C,F,A,H--88161193(+) AACCCA/GCCACC 1 -- int18Minor allele frequency- G:0.32NA WA EA 252
    rs123422411,2
    --88161326(+) gagccA/Cccatg 1 -- int10--------
    rs31856511,2
    C,F--88161527(-) GTAGTC/GCAGGG 1 -- ut314Minor allele frequency- G:0.11NA WA 124
    rs1894223401,2
    --88161720(+) ACTTGA/CTGCAG 1 -- ut310--------
    rs1414214251,2
    C--88161834(+) ATATCA/GAAAAT 1 -- ut310--------
    rs1928760441,2
    --88161839(+) GAAAAC/TAAAAC 1 -- ut310--------
    rs1470242071,2
    C--88161898(+) CAAACC/TGGCCC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for AGTPBP1 (88161454 - 88356944 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for AGTPBP1 (see all 17):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2738683CNV Deletion23290073
    nsv6593CNV Insertion18451855
    nsv525362CNV Loss19592680
    nsv524134CNV Loss19592680
    nsv831645CNV Loss17160897
    nsv893532CNV Loss21882294
    dgv8257n71CNV Loss21882294
    nsv893534CNV Loss21882294
    dgv8256n71CNV Loss21882294
    nsv893524CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing AGTPBP1
    DNA2.0 Custom Variant and Variant Library Synthesis for AGTPBP1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 606830    OMIM disorders: --


    Find genes that share disorders with AGTPBP1           About GenesLikeMe

    Genetic Association Database (GAD): AGTPBP1
    Human Genome Epidemiology (HuGE) Navigator: AGTPBP1 (1 document)

    Export disorders for AGTPBP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for AGTPBP1 gene, integrated from 10 sources (see all 22):
    (articles sorted by number of sources associating them with AGTPBP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    2. Regenerating motor neurons express Nna1, a novel ATP/GTP-binding protein related to zinc carboxypeptidases. (PubMed id 11083920)1, 3 Harris A....Soares H.D. (Mol. Cell. Neurosci. 2000)
    3. Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10470851)1, 2 Kikuno R.... Ohara O. (DNA Res. 1999)
    4. Identification of CRM1-dependent Nuclear Export Cargos Using Quantitative Mass Spectrometry. (PubMed id 23242554)1 Thakar K....Kehlenbach R.H. (amp 2013)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    6. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    7. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    8. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (Anal. Chem. 2009)
    9. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (Sci. Signal. 2009)
    10. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 23287 HGNC: 17258 AceView: AGTPBP1 Ensembl:ENSG00000135049 euGenes: HUgn23287
    ECgene: AGTPBP1 H-InvDB: AGTPBP1

    (According to HUGE)
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    HUGE: KIAA1035

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for AGTPBP1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for AGTPBP1 gene:
    Search GeneIP for patents involving AGTPBP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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