Aliases for AGTPBP1 Gene
External Ids for AGTPBP1 Gene
Previous GeneCards Identifiers for AGTPBP1 Gene
NNA1 is a zinc carboxypeptidase that contains nuclear localization signals and an ATP/GTP-binding motif that was initially cloned from regenerating spinal cord neurons of the mouse.[supplied by OMIM, Jul 2002]
GeneCards Summary for AGTPBP1 Gene
AGTPBP1 (ATP/GTP Binding Protein 1) is a Protein Coding gene. Among its related pathways are Neuroscience. GO annotations related to this gene include tubulin binding and metallocarboxypeptidase activity. An important paralog of this gene is AGBL2.
UniProtKB/Swiss-Prot for AGTPBP1 Gene
Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5.