AGRP Gene
protein-coding GIFtS: 57
GCID: GC16M067516
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|
agouti related protein homolog (mouse)(Previous name: agouti (mouse) related protein )
| |
Aliases
for AGRP gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Agouti Related Protein Homolog (Mouse)1 2 | | Agrt1 | | ART1 2 3 5 | | Agouti (Mouse) Related Protein1 | | AGRT2 3 5 | | Agouti-Related Protein2 | | ASIP21 2 | | |
Export aliases for AGRP gene to outside databasesPrevious GC identifers: GC16M058210 GC16M067894 GC16M067251 GC16M067292 GC16M066073 GC16M053389 |
Summaries
for AGRP gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for AGRP:
This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamiccontrol of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a rolein weight homeostasis. Mutations in this gene have been associated with late on-set obesity. (provided by RefSeq, Dec2009)
UniProtKB/Swiss-Prot: AGRP_HUMAN, O00253Function: Plays a role in weight homeostasis. Involved in the control of feeding behavior through the centralmelanocortin system. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated bystimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R (Bysimilarity). Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity. It promotesMC3R and MC4R endocytosis in an arrestin-dependent manner
Gene Wiki entry for AGRP (Agouti-related peptide)
|
Genomic Views
for AGRP gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010498.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the AGRP gene promoter:
CREB
Other transcription factors
Search SABiosciences Chromatin IP Primers for AGRP
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AGRP |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16q22 Ensembl cytogenetic band: 16q22.1 HGNC cytogenetic band: 16q22AGRP Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16M067516: view genomic region
(about GC identifiers)
Start:
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67,516,474 bp from pter |
End:
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67,517,716 bp from pter |
Size:
|
1,243 bases |
Orientation:
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minus strand |
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Proteins
for AGRP gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: AGRP_HUMAN, O00253 (See
protein sequence)Recommended Name: Agouti-related protein precursor Size: 132 amino acids; 14440 Da
Subunit: Interacts with melanocortin receptors MC3R, MC4R and MC5R
Subcellular location: Secreted. Golgi apparatus lumen
3 PDB 3D structures from  and Proteopedia  for AGRP:1HYK (3D)
1MR0 (3D)
2IQV (3D)
Secondary accessions: O15459 Q2TBD9Explore the universe of human proteins at neXtProt for AGRP: NX_O00253
AGRP Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001129.1
ENSEMBL proteins: ENSP00000290953
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
AGRP for ontologies About GeneDecksing
AGRP Antibody Products:
Assay Products for AGRP: |
Protein
Domains /
Families
for AGRP gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
AGRP for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry O00253ProtoNet protein and cluster: O00253 1 Blocks protein family: IPB007733 Agouti
UniProtKB/Swiss-Prot: AGRP_HUMAN, O00253Domain: The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottinSimilarity: Contains 1 agouti domain |
Function
for AGRP gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: AGRP_HUMAN, O00253Function: Plays a role in weight homeostasis. Involved in the control of feeding behavior through the centralmelanocortin system. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated bystimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R (Bysimilarity). Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity. It promotesMC3R and MC4R endocytosis in an arrestin-dependent manner Genatlas biochemistry entry for AGRP:mouse agouti related protein,primarily expressed in adrenal gland,subthalamic mucleus,hypothalamus,potent antagonist ofmelanocortin receptor MICR3,MICR4, implicated in body weight regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for AGRP (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for AGRP (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for AGRP | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AGRP |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
AGRP for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for AGRP:
Animal Models:
Mouse knock-outs for AGRP: Agrp/Atp6v0d1Agrp/tm1Rpa Agrptm1Sqn
9 MGI mutant phenotypes (inferred from 6 alleles ) (MGI details for Agrp):
AGRP for phenotypes About GeneDecksing
|
Pathways & Interactions
for AGRP gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Adenylate cyclase-activating neuropeptides | | | 2 | Syndecan-3-mediated signaling events | | | 3 | Development_Leptin signaling via PI3K-dependent pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for AGRP
1  BioSystems Pathway for AGRP
1 
Kegg Pathway (Kegg details for AGRP):
AGRP for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for AGRP
STRING Interaction
Network Preview (showing 5 interactants - click image to see 13)
5/13 Interacting proteins for AGRP (O002533 ENSP000002909534) via UniProtKB, MINT, STRING, and/or I2D (see all 13)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table
AGRP for ontologies About GeneDecksing
|
Drugs & Compounds
for AGRP gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
AGRP for compounds About GeneDecksing
 Browse Tocris compounds for AGRP
10/14 Novoseek chemical compound relationships for AGRP gene (see all 14) About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| alpha msh |
82.9 |
7 |
10902813 (2), 10657511 (1), 9751529 (1), 15481810 (1) (see all 6) |
| oxyntomodulin |
69.6 |
2 |
15082874 (1) |
| cocaine |
57.5 |
19 |
16210367 (2), 18061414 (1), 18971258 (1), 10657511 (1) (see all 18) |
| tcep |
53.3 |
1 |
9724530 (1) |
| cystine |
50.7 |
2 |
16009463 (1), 15509165 (1) |
| acth |
36.7 |
11 |
12697678 (5), 16914082 (1), 14694081 (1), 17208361 (1) |
| glucose |
24.7 |
46 |
17974626 (5), 19770186 (3), 20404050 (3), 15375032 (3) (see all 12) |
| amphetamine |
13.6 |
3 |
10657511 (1), 15777192 (1), 16935329 (1) |
| n-ethylmaleimide |
12.2 |
1 |
9724530 (1) |
| 2-deoxyglucose |
10.2 |
13 |
15375032 (3), 16978589 (1) |
Search CenterWatch for drugs/clinical trials and news about AGRP
|
Transcripts
for AGRP gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for AGRP gene: NM_001138.1 Unigene Cluster for AGRP: Agouti related protein homolog (mouse) Hs.104633 [show with all ESTs]Unigene Representative Sequence: BG4607881 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000290953(uc002etg.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for AGRP (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for AGRP (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: AGRP (NM_001138) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for AGRP | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AGRP |
Additional cDNA sequence: BC110443.2 U88063.1 U89485.1 2 DOTS entries: DT.307995 DT.95152059 11 AceView cDNA sequences: CD369732 NM_001138 NM_007316 AI572835 AW135422 U89485 AI823322 H63735 AI572816 H63298 BU428489
GeneLoc Exon Structure
|
Expression
for AGRP gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| AGRP expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AATCCCTGCA
About this image
See AGRP Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for AGRP
SOURCE GeneReport for Unigene cluster: Hs.104633
UniProtKB/Swiss-Prot: AGRP_HUMAN, O00253Tissue specificity: Expressed primarily in the adrenal gland, subthalamic nucleus, and hypothalamus, with a lower levelof expression occurring in testis, lung, and kidney
SABiosciences Expression via Pathway-Focused PCR Array including AGRP:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for AGRP
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat AGRP | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat AGRP | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AGRP |
Orthologs
for AGRP gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for AGRP gene from 3/9 species (see all 9) About this table
ENSEMBL Gene Tree for AGRP (if available)
TreeFam Gene Tree for AGRP (if available) |
Paralogs
for AGRP gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for AGRP gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for AGRP (67516474 - 67517716 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for AGRP: --
Human Gene Mutation Database (HGMD): AGRP
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing AGRP |
|
Disorders
/ Diseases
for AGRP gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
AGRP for disorders About GeneDecksing
OMIM gene information: 602311
OMIM disorders: 601665
UniProtKB/Swiss-Prot: AGRP_HUMAN, O00253
Genetic variations in AGRP may be a cause of obesity (OBESITY) [MIM:601665]. It is a condition characterizedby an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessiveaccumulation of body fat
19  diseases for AGRP: About MalaCardsleanness, inherited obesity, late-onset prader-willi syndrome obesity
retinol binding protein anorexia nervosa eating disorder autism spectrum disorder
overnutrition fatty liver disease morbid obesity cushing's syndrome
gliosis liver disease hyperglycemia neurodegeneration
thyroiditis pancreatitis neuronitis
8 Novoseek disease relationships for AGRP gene About this table
Genetic Association Database (GAD): AGRP
Human Genome Epidemiology (HuGE) Navigator: AGRP (14 documents)
Export disorders for AGRP gene to outside databases
|
Publications
for AGRP gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for AGRP gene, integrated from 9 sources (see all 208):
(articles sorted by number of sources associating them with AGRP) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Association between an agouti-related protein gene polymorphism and anorexia nervosa. (PubMed id 11326303)1, 2, 4, 9 Vink T.... Adan R.A. (2001)
- Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein. (PubMed id 9311920)1, 2, 3, 9 Ollmann M.M....Barsh G.S. (1997)
- Hypothalamic expression of ART, a novel gene related to agouti, is up-regulated in obese and diabetic mutant mice. (PubMed id 9119224)1, 2, 3 Shutter J.R....Stark K.L. (1997)
- NMR structure of a minimized human agouti related protein prepared by total chemical synthesis. (PubMed id 10371151)1, 2, 9 Bolin K.A.... Millhauser G.L. (1999)
- Characterization of Agouti-related protein binding to melanocortin receptors. (PubMed id 9892020)1, 2, 9 Yang Y.K....Gantz I. (1999)
- Determination of disulfide structure in agouti-related protein (AGRP) by stepwise reduction and alkylation. (PubMed id 9724530)1, 2, 9 Bures E.J.... Haniu M. (1998)
- Two ethnic-specific polymorphisms in the human Agouti-related protein gene are associated with macronutrient intake. (PubMed id 16280444)1, 4, 9 Loos R.J....Argyropoulos G. (2005)
- The natural inverse agonist agouti-related protein induces arrestin-mediated endocytosis of melanocortin-3 and -4 receptors. (PubMed id 17041250)1, 2, 9 Breit A....Gudermann T. (2006)
- Mutational analysis of melanocortin-4 receptor, agouti-related protein, and alpha-melanocyte-stimulating hormone genes in severely obese children. (PubMed id 11487744)1, 4, 9 Dubern B.... Tounian P. (2001)
- Ala67Thr polymorphism in the Agouti-related peptide gene is associated with inherited leanness in humans. (PubMed id 15054840)1, 4, 9 Marks D.L....Cone R.D. (2004)
|
External Searches for AGRP gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing AGRP gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing AGRP gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing AGRP gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for AGRP | Pharmacogenomics, SNPs, Pathways | | SeattleSNPs | http://pga.gs.washington.edu/data/agrp/ |
|
| | |
About This Section
| Patent Information for AGRP gene:
Search GeneIP for patents involving AGRP
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for AGRP gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for AGRP | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for AGRP | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for AGRP | | | OriGene Protein Over-expression Lysate for AGRP | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for AGRP | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for AGRP | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for AGRP | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for AGRP | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for AGRP | | OriGene Custom Protein Services for AGRP | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat AGRP | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing AGRP | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AGRP | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat AGRP | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AGRP | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat AGRP |
| |
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| |  |  |  |  | | | | | | Recombinant Protein for AGRP |
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 |
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| | | |  |  |  | | | | Search ThermoFisher Antibodies for AGRP |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AGRP |
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