Aliases for AGPS Gene
External Ids for AGPS Gene
Previous GeneCards Identifiers for AGPS Gene
This gene is a member of the FAD-binding oxidoreductase/transferase type 4 family. It encodes a protein that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetonephosphate (DHAP) is converted to alkyl-DHAP by the addition of a long chain alcohol and the removal of a long-chain acid anion. The protein is localized to the inner aspect of the peroxisomal membrane and requires FAD as a cofactor. Mutations in this gene have been associated with rhizomelic chondrodysplasia punctata, type 3 and Zellweger syndrome. [provided by RefSeq, Jul 2008]
GeneCards Summary for AGPS Gene
AGPS (Alkylglycerone Phosphate Synthase) is a Protein Coding gene. Diseases associated with AGPS include rhizomelic chondrodysplasia punctata, type 3 and rhizomelic chondrodysplasia punctata. Among its related pathways are Metabolism and Metabolism. GO annotations related to this gene include FAD binding and alkylglycerone-phosphate synthase activity. An important paralog of this gene is LDHD.
UniProtKB/Swiss-Prot for AGPS Gene
Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids.