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AGMAT Gene

protein-coding   GIFtS: 54
GCID: GC01M015898

Agmatine Ureohydrolase (Agmatinase)

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Agmatine Ureohydrolase (Agmatinase)1 2
AUH2 3
EC 3.5.3.113 8
Agmatinase, Mitochondrial2
Agmatine Ureohydrolase3
EC 3.5.38

External Ids:    HGNC: 184071   Entrez Gene: 798142   Ensembl: ENSG000001167717   UniProtKB: Q9BSE53   

Export aliases for AGMAT gene to outside databases

Previous GC identifers: GC01M015296 GC01M015078 GC01M015050 GC01M015262 GC01M015261 GC01M015644 GC01M015772 GC01M014418


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for AGMAT Gene:
AGMAT (agmatine ureohydrolase (agmatinase)) is a protein-coding gene. GO annotations related to this gene include agmatinase activity. An important paralog of this gene is ARG2.

Gene Wiki entry for AGMAT (Agmatinase) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NC_018912.2  NT_032977.10  
Regulatory elements:
   Regulatory transcription factor binding sites in the AGMAT gene promoter:
         Bach1   USF1   AP-2gamma   C/EBPalpha   c-Ets-1   S8   USF-1   c-Myb   SEF-1 (1)   En-1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for AGMAT

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat AGMAT


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p36.21   Ensembl cytogenetic band:  1p36.21   HGNC cytogenetic band: 1p36.13

AGMAT Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AGMAT gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M015898:  view genomic region     (about GC identifiers)

Start:
15,898,194 bp from pter      End:
15,911,605 bp from pter
Size:
13,412 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: SPEB_HUMAN, Q9BSE5 (See protein sequence)
Recommended Name: Agmatinase, mitochondrial precursor  
Size: 352 amino acids; 37660 Da
Cofactor: Manganese (Potential)
Secondary accessions: Q5TDH1 Q9H5J3

Explore the universe of human proteins at neXtProt for AGMAT: NX_Q9BSE5

Explore proteomics data for AGMAT at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for AGMAT (Q9BSE5) (see all 5)
     RPGARFGP  QALEIIRGC  ANLLFEMLC  RVVQIGIRGSS 


    See AGMAT Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_079034.3  
    ENSEMBL proteins: 
     ENSP00000364986  
    Reactome Protein details: Q9BSE5

    AGMAT Human Recombinant Protein Products:

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    OriGene Protein Over-expression Lysate for AGMAT
    OriGene MassSpec for AGMAT
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    Novus Biologicals AGMAT Protein
    Novus Biologicals AGMAT Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for AGMAT

     
    Search eBioscience for Proteins for AGMAT 

     
    antibodies-online proteins for AGMAT (4 products) 

     
    antibodies-online peptides for AGMAT

    AGMAT Antibody Products:

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    antibodies-online antibodies for AGMAT (17 products) 

    AGMAT Assay Products:

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    Cloud-Clone Corp. ELISAs for AGMAT
    Cloud-Clone Corp. CLIAs for AGMAT
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    antibodies-online kits for AGMAT (8 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    4 InterPro protein domains:
     IPR006035 Ureohydrolase
     IPR023696 Ureohydrolase_domain
     IPR020855 Ureohydrolase_Mn_BS
     IPR005925 Agmatinase-rel

    Graphical View of Domain Structure for InterPro Entry Q9BSE5

    ProtoNet protein and cluster: Q9BSE5

    2 Blocks protein domains:
    IPB005924 Arginase signature
    IPB006035 Arginase/agmatinase/formiminoglutamase


    UniProtKB/Swiss-Prot: SPEB_HUMAN, Q9BSE5
    Similarity: Belongs to the arginase family. Agmatinase subfamily


    Find genes that share domains with AGMAT           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SPEB_HUMAN, Q9BSE5
    Catalytic activity: Agmatine + H(2)O = putrescine + urea

         Enzyme Numbers (IUBMB): EC 3.5.3.111 2 EC 3.5.32

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008783agmatinase activity IEA--
    GO:0016813hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines ----
    GO:0046872metal ion binding IEA--
         
    Find genes that share ontologies with AGMAT           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for AGMAT

    miRNA
    Products:
        
    miRTarBase miRNAs that target AGMAT:
    hsa-mir-1 (MIRT001392), hsa-let-7e-5p (MIRT051619), hsa-mir-26b-5p (MIRT029705)

    Block miRNA regulation of human, mouse, rat AGMAT using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate AGMAT:
    hsa-miR-922 hsa-miR-33b hsa-miR-33a
    SwitchGear 3'UTR luciferase reporter plasmidAGMAT 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for AGMAT
    Predesigned siRNA for gene silencing in human, mouse, rat AGMAT

    Gene Editing
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AGMAT

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AGMAT


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SPEB_HUMAN, Q9BSE5: Mitochondrion
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    cytosol2
    peroxisome2

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion TAS--

    Find genes that share ontologies with AGMAT           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for AGMAT About    
    See pathways by source

    SuperPathContained pathways About
    1Metabolism
    Metabolism0.38
    Metabolic pathways0.38
    2Metabolism of amino acids and derivatives
    Metabolism of amino acids and derivatives
    Agmatine biosynthesis0.00
    Metabolism of polyamines0.00
    3Arginine and proline metabolism
    Arginine and proline metabolism


    Find genes that share SuperPaths with AGMAT           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Reactome Pathway for AGMAT
        Agmatine biosynthesis


    2 Kegg Pathways  (Kegg details for AGMAT):
        Arginine and proline metabolism
    Metabolic pathways

    UniProtKB/Swiss-Prot: SPEB_HUMAN, Q9BSE5
    Pathway: Amine and polyamine biosynthesis; putrescine biosynthesis via agmatine pathway; putrescine from agmatine:
    step 1/1

        Pathway & Disease-focused RT2 Profiler PCR Array including AGMAT: 

              Amino Acid Metabolism I in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for AGMAT

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for AGMAT (ENSP000003649864) via UniProtKB, MINT, STRING, and/or I2D (see all 37)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ADCENSP000002945174STRING: ENSP00000294517
    AOC1ENSP000003541934STRING: ENSP00000354193
    DEPDC1ENSP000004122924STRING: ENSP00000412292
    ODC1ENSP000002341114STRING: ENSP00000234111
    SAT1ENSP000003685724STRING: ENSP00000368572
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006595polyamine metabolic process TAS--
    GO:0008295spermidine biosynthetic process IEA--
    GO:0033388putrescine biosynthetic process from arginine IEA--
    GO:0034641cellular nitrogen compound metabolic process TAS--
    GO:0044281small molecule metabolic process TAS--

    Find genes that share ontologies with AGMAT           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for AGMAT (SPEB)

    10 HMDB Compounds for AGMAT    About this table
    CompoundSynonyms CAS #PubMed Ids
    Agmatine(4-Aminobutyl)guanidine (see all 11)306-60-5--
    Guanidine(4-Aminobutyl) guanidine (see all 8)50-01-1--
    Manganesemanganese 7439-96-5--
    N1-AcetylspermineN'-Acetylspermine (see all 6)25593-72-0--
    NorspermidineN-(3-aminopropyl)-1,3-Propanediamine (see all 28)56-18-8--
    Putrescine1,4-Butanediamine (see all 8)110-60-1--
    Spermidine1,5,10-Triazadecane (see all 15)124-20-9--
    Spermine1,5,10,14-Tetraazatetradecane (see all 18)71-44-3--
    UreaCarbonyl diamine (see all 90)57-13-6--
    WaterDihydrogen oxide (see all 2)7732-18-5--

    10 Novoseek inferred chemical compound relationships for AGMAT gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    agmatine 93.8 14 9494113 (1), 14648699 (1), 15522599 (1), 11914032 (1) (see all 11)
    hexamethylenediamine 83.7 1 16511187 (1)
    putrescine 79.3 7 9494113 (1), 9851555 (1), 14648699 (1), 15522599 (1) (see all 7)
    arginine 65.6 13 15090903 (3), 9494113 (1), 16128822 (1), 11914032 (1) (see all 6)
    ornithine 60.3 2 19286931 (1), 11804860 (1)
    spermidine 45 1 15355972 (1)
    spermine 43.3 1 15355972 (1)
    amine 40 1 9494113 (1)
    manganese 30.6 1 15355972 (1)
    morphine 19.5 1 17025265 (1)



    Find genes that share compounds with AGMAT           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for AGMAT gene: 
    NM_024758.4  

    Unigene Cluster for AGMAT:

    Agmatine ureohydrolase (agmatinase)
    Hs.461532  [show with all ESTs]
    Unigene Representative Sequence: NM_024758
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000375826(uc001awv.2)
    miRNA
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    3 qRT-PCR Assays for microRNAs that regulate AGMAT:
    hsa-miR-922 hsa-miR-33b hsa-miR-33a
    SwitchGear 3'UTR luciferase reporter plasmidAGMAT 3' UTR sequence
    Inhib. RNA
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    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat AGMAT
      QuantiTect SYBR Green Assays in human, mouse, rat AGMAT
      QuantiFast Probe-based Assays in human, mouse, rat AGMAT

    Additional mRNA sequence: 

    AK130034.1 AK225366.1 AY057097.1 BC005090.1 

    8 DOTS entries:

    DT.308843  DT.95164407  DT.91828828  DT.100745527  DT.97839308  DT.100751882  DT.86854932  DT.95164406 

    Selected AceView cDNA sequences (see all 84):

    BE465248 AI492488 AI261350 AW058507 AW611892 BM853724 AW611556 AI439108 
    AI653589 AW614215 AA934764 AW299579 BF476183 F32232 AI186209 AI521141 
    AW206473 BU675534 BM788254 CA312785 BM423464 NM_024758 BM827493 AI625982 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for AGMAT    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7
    SP1:                                                      
    SP2:                                -                     


    ECgene alternative splicing isoforms for AGMAT

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    AGMAT expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    AGMAT Expression
    About this image

    AGMAT Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    AGMAT Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.461532

    UniProtKB/Swiss-Prot: SPEB_HUMAN, Q9BSE5
    Tissue specificity: Highly expressed in liver and kidney. Also found in skeletal muscle, fetal liver, brain,
    testis, skin and the gastrointestinal tract. Within brain, expression is higher in the cerebral cortex with lower
    levels in the medulla and spinal cord

        Pathway & Disease-focused RT2 Profiler PCR Array including AGMAT: 
              Amino Acid Metabolism I in human mouse rat

    Primer
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    QuantiFast Probe-based Assays in human, mouse, rat AGMAT
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AGMAT

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for AGMAT gene from Selected species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Agmat1 , 5 agmatine ureohydrolase (agmatinase)1, 5 82.48(n)1
    84.09(a)1
      4 (74.75 cM)5
    759861  NM_001081408.11  NP_001074877.11 
     1417466725 
    chicken
    (Gallus gallus)
    Aves AGMAT1 agmatine ureohydrolase (agmatinase) 73.77(n)
    80.88(a)
      373942  NM_204143.2  NP_989474.1 
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia agmat1 agmatine ureohydrolase (agmatinase) 70.99(n)
    78.48(a)
      496991  XM_002942812.2  XP_002942858.2 
    zebrafish
    (Danio rerio)
    Actinopterygii agmat1 agmatine ureohydrolase (agmatinase) 65.51(n)
    70.57(a)
      556522  NM_001077551.1  NP_001071019.1 
    worm
    (Caenorhabditis elegans)
    Secernentea T21F4.16
    Protein T21F4.1, isoform a
    13(a)
    1 ↔ 1
    X(5630356-5638098) WBGene00020658
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes CAR16
    Arginase, responsible for arginine degradation, ex...
    18(a)
    1 → many
    XVI(339944-340945) YPL111W
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT4G089001 AT4G08900 45.93(n)
    37.79(a)
      826468  NM_116959.3  NP_192629.1 
    rice
    (Oryza sativa)
    Liliopsida Os04g01063001 Os04g0106300 46.16(n)
    36.6(a)
      4334912  NM_001058548.1  NP_001052013.1 


    ENSEMBL Gene Tree for AGMAT (if available)
    TreeFam Gene Tree for AGMAT (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for AGMAT gene
    ARG22  ARG12  

    Find genes that share paralogs with AGMAT           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for AGMAT (see all 369)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs344141681,2
    F--15898831(+) TGAGCC/TACTGG 1 -- ut311Minor allele frequency- T:0.06WA 118
    rs1918934171,2
    --15898841(+) GGTCCA/GGCCTG 1 -- ut310--------
    rs595134621,2
    C,F--15898940(+) ACCTCC/TACCTC 1 -- ut312Minor allele frequency- T:0.50NA CSA 4
    rs1124860691,2
    C,F--15898941(+) CCTCCG/ACCTCC 1 -- ut311Minor allele frequency- A:0.50WA 2
    rs1888518111,2
    C--15899003(+) GCACGC/TGCCAC 1 -- ut310--------
    rs1385083101,2
    --15899015(+) ACGCCC/TAGCTA 1 -- ut310--------
    rs1450573181,2
    C--15899025(+) AACTT-/CTGTAT 1 -- ut310--------
    rs1928900931,2
    --15899052(+) TTTTCA/CCCATG 1 -- ut310--------
    rs1857339281,2
    --15899113(+) GCCCCC/GCAAAG 1 -- ut310--------
    rs1496376411,2
    --15899141(+) TGAGCC/TACCGT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for AGMAT (15898194 - 15911605 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for AGMAT: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing AGMAT
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with AGMAT           About GenesLikeMe

    2 Novoseek inferred disease relationships for AGMAT gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    carcinoma renal cell 23.3 1 14648699 (1)
    tumors 0 2 14648699 (2)

    Genetic Association Database (GAD): AGMAT
    Human Genome Epidemiology (HuGE) Navigator: AGMAT (3 documents)

    Export disorders for AGMAT gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for AGMAT gene, integrated from 10 sources (see all 39):
    (articles sorted by number of sources associating them with AGMAT)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning of human agmatinase. An alternate path for polyamine synthesis induced in liver by hepatitis B virus. (PubMed id 11804860)1, 2, 3, 9 Mistry S.K.... Morris S.M. Jr. (Am. J. Physiol. 2002)
    2. Cloning and characterization of human agmatinase. (PubMed id 11914032)1, 2, 3, 9 Iyer R.K....Cederbaum S.D. (Mol. Genet. Metab. 2002)
    3. Human agmatinase is diminished in the clear cell type of renal cell carcinoma. (PubMed id 14648699)1, 3, 9 Dallmann K....Walther R. (Int. J. Cancer 2004)
    4. Novel association strategy with copy number variation for identifying new risk Loci of human diseases. (PubMed id 20808825)1, 4 Chen X....Kong X. (PLoS ONE 2010)
    5. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    6. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    7. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    10. Expression, crystallization and preliminary X-ray crystallographic analysis of human agmatinase. (PubMed id 16511187)1, 9 Kim K.H....Suh S.W. (Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79814 HGNC: 18407 AceView: AGMAT Ensembl:ENSG00000116771 euGenes: HUgn79814
    ECgene: AGMAT Kegg: 79814 H-InvDB: AGMAT

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for AGMAT Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for AGMAT gene:
    Search GeneIP for patents involving AGMAT

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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