Aliases for AGBL3 Gene
External Ids for AGBL3 Gene
Previous GeneCards Identifiers for AGBL3 Gene
GeneCards Summary for AGBL3 Gene
AGBL3 (ATP/GTP Binding Protein Like 3) is a Protein Coding gene. Diseases associated with AGBL3 include Crest Syndrome. Gene Ontology (GO) annotations related to this gene include metallocarboxypeptidase activity. An important paralog of this gene is AGBL2.
UniProtKB/Swiss-Prot for AGBL3 Gene
Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin.
Isoform 2: Metallocarboxypeptidase that mediates tubulin deglutamylation.