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Aliases for AGAP9 Gene

Aliases for AGAP9 Gene

  • ArfGAP With GTPase Domain, Ankyrin Repeat And PH Domain 9 2 3
  • Centaurin, Gamma-Like Family, Member 6 2 3
  • Centaurin-Gamma-Like Family Member 6 3 4
  • CTGLF6 3 4
  • AGAP-9 3 4
  • Arf-GAP With GTPase, ANK Repeat And PH Domain-Containing Protein 9 3
  • BA301J7.2 3

External Ids for AGAP9 Gene

Previous Symbols for AGAP9 Gene

  • CTGLF6

Summaries for AGAP9 Gene

GeneCards Summary for AGAP9 Gene

AGAP9 (ArfGAP With GTPase Domain, Ankyrin Repeat And PH Domain 9) is a Protein Coding gene. GO annotations related to this gene include phospholipid binding. An important paralog of this gene is ASAP3.

UniProtKB/Swiss-Prot for AGAP9 Gene

  • Putative GTPase-activating protein.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AGAP9 Gene

Genomics for AGAP9 Gene

Genomic Location for AGAP9 Gene

Start:
47,501,854 bp from pter
End:
47,549,750 bp from pter
Size:
47,897 bases
Orientation:
Minus strand

Genomic View for AGAP9 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for AGAP9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for AGAP9 Gene

Regulatory Elements for AGAP9 Gene

Proteins for AGAP9 Gene

  • Protein details for AGAP9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5VTM2-AGAP9_HUMAN
    Recommended name:
    Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 9
    Protein Accession:
    Q5VTM2
    Secondary Accessions:
    • D3YTF3

    Protein attributes for AGAP9 Gene

    Size:
    703 amino acids
    Molecular mass:
    77972 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • Encoded by one of the numerous copies of centaurin gamma-like genes clustered in the q11 region of chromosome 10
    SequenceCaution:
    • Sequence=CAH72201.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for AGAP9 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for AGAP9 Gene

Proteomics data for AGAP9 Gene at MOPED

Post-translational modifications for AGAP9 Gene

No Post-translational modifications

Other Protein References for AGAP9 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for AGAP9 Gene

Domains for AGAP9 Gene

Gene Families for AGAP9 Gene

HGNC:
  • PLEKH :Pleckstrin homology (PH) domain containing
  • ArfGAP :ADP-ribosylation factor GTPase activating proteins
  • ANKRD :Ankyrin repeat domain containing

Protein Domains for AGAP9 Gene

UniProtKB/Swiss-Prot:

AGAP9_HUMAN
Domain:
  • Contains 1 Arf-GAP domain.:
    • Q5VTM2
  • Contains 1 PH domain.:
    • Q5VTM2
Family:
  • Belongs to the centaurin gamma-like family.:
    • Q5VTM2
Similarity:
  • Contains 1 ANK repeat.:
    • Q5VTM2
genes like me logo Genes that share domains with AGAP9: view

Function for AGAP9 Gene

Molecular function for AGAP9 Gene

UniProtKB/Swiss-Prot Function: Putative GTPase-activating protein.

Gene Ontology (GO) - Molecular Function for AGAP9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003924 GTPase activity --
GO:0005096 GTPase activator activity IEA --
GO:0005525 GTP binding --
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with AGAP9: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for AGAP9 Gene

Localization for AGAP9 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for AGAP9 Gene COMPARTMENTS Subcellular localization image for AGAP9 gene
Compartment Confidence
cytosol 3
nucleus 2
cytoskeleton 1

No data available for Gene Ontology (GO) - Cellular Components for AGAP9 Gene

Pathways for AGAP9 Gene

SuperPathways for AGAP9 Gene

No Data Available

Interacting Proteins for AGAP9 Gene

Gene Ontology (GO) - Biological Process for AGAP9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0043547 positive regulation of GTPase activity IEA --
genes like me logo Genes that share ontologies with AGAP9: view

No data available for Pathways by source for AGAP9 Gene

Transcripts for AGAP9 Gene

mRNA/cDNA for AGAP9 Gene

(1) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for AGAP9 Gene

ArfGAP with GTPase domain, ankyrin repeat and PH domain 9:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for AGAP9 Gene

No ASD Table

Relevant External Links for AGAP9 Gene

GeneLoc Exon Structure for
AGAP9
ECgene alternative splicing isoforms for
AGAP9

Expression for AGAP9 Gene

mRNA expression in normal human tissues for AGAP9 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for AGAP9 Gene

SOURCE GeneReport for Unigene cluster for AGAP9 Gene Hs.645346

genes like me logo Genes that share expressions with AGAP9: view

Orthologs for AGAP9 Gene

This gene was present in the common ancestor of animals.

Orthologs for AGAP9 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 37
  • 76 (a)
OneToMany
CTGLF2 36
  • 97.44 (n)
  • 94.71 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 58 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 42 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 37
  • 50 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 8 (a)
ManyToMany
-- 37
  • 56 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii agap1 37
  • 42 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta cenG1A 37
  • 23 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea cnt-2 37
  • 18 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 31 (a)
OneToMany
Species with no ortholog for AGAP9:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for AGAP9 Gene

ENSEMBL:
Gene Tree for AGAP9 (if available)
TreeFam:
Gene Tree for AGAP9 (if available)

Paralogs for AGAP9 Gene

Selected SIMAP similar genes for AGAP9 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with AGAP9: view

Variants for AGAP9 Gene

Structural Variations from Database of Genomic Variants (DGV) for AGAP9 Gene

Variant ID Type Subtype PubMed ID
dgv252e1 CNV Complex 17122850
esv2750898 CNV Loss 17911159
dgv254e1 CNV Complex 17122850
nsv516485 CNV Gain+Loss 19592680
nsv895114 CNV Gain 21882294
esv34875 CNV Gain 17911159
nsv510991 OTHER Complex 20534489
dgv256e1 CNV Complex 17122850
dgv257e1 CNV Complex 17122850
esv22204 CNV Gain+Loss 19812545
dgv258e1 CNV Complex 17122850
nsv8636 CNV Gain+Loss 18304495
nsv436102 CNV Deletion 17901297
nsv7203 OTHER Inversion 18451855
esv2736152 CNV Deletion 23290073
dgv656n71 CNV Gain 21882294
esv2736163 CNV Deletion 23290073
dgv259e1 CNV Complex 17122850
dgv260e1 CNV Complex 17122850
nsv895135 CNV Loss 21882294
dgv660n71 CNV Gain 21882294
dgv661n71 CNV Gain 21882294
dgv262e1 CNV Complex 17122850
dgv23e55 CNV Loss 17911159
dgv24e55 CNV Gain 17911159
nsv821667 CNV Gain 15273396
nsv470934 CNV Gain 18288195
nsv818758 CNV Gain 17921354
dgv665n71 CNV Gain 21882294
dgv264e1 CNV Complex 17122850
nsv831853 CNV Gain 17160897
dgv666n71 CNV Gain 21882294
nsv831854 CNV Gain 17160897
esv2663732 CNV Deletion 23128226
dgv667n71 CNV Loss 21882294
dgv668n71 CNV Gain 21882294
nsv467059 CNV Gain 19166990
esv21870 CNV Gain+Loss 19812545
nsv895340 CNV Gain 21882294
nsv831860 CNV Gain 17160897
dgv269e1 CNV Complex 17122850
dgv696n71 CNV Gain 21882294

Relevant External Links for AGAP9 Gene

HapMap Linkage Disequilibrium report
AGAP9

No data available for Sequence variations from dbSNP and Humsavar for AGAP9 Gene

Disorders for AGAP9 Gene

No disorders were found for AGAP9 Gene.

No data available for UniProtKB/Swiss-Prot for AGAP9 Gene

Publications for AGAP9 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  3. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for AGAP9 Gene

Sources for AGAP9 Gene

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