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Aliases for AGAP9 Gene

Aliases for AGAP9 Gene

  • ArfGAP With GTPase Domain, Ankyrin Repeat And PH Domain 9 2 3 5
  • Centaurin, Gamma-Like Family, Member 6 2 3
  • Centaurin-Gamma-Like Family Member 6 3 4
  • CTGLF6 3 4
  • AGAP-9 3 4
  • BA301J7.2 3

External Ids for AGAP9 Gene

Previous HGNC Symbols for AGAP9 Gene

  • CTGLF6

Previous GeneCards Identifiers for AGAP9 Gene

  • GC10P047809
  • GC10P047834
  • GC10P048214
  • GC10P048189

Summaries for AGAP9 Gene

GeneCards Summary for AGAP9 Gene

AGAP9 (ArfGAP With GTPase Domain, Ankyrin Repeat And PH Domain 9) is a Protein Coding gene. GO annotations related to this gene include GTP binding and GTPase activator activity. An important paralog of this gene is ASAP3.

UniProtKB/Swiss-Prot for AGAP9 Gene

  • Putative GTPase-activating protein.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AGAP9 Gene

Genomics for AGAP9 Gene

Regulatory Elements for AGAP9 Gene

Genomic Location for AGAP9 Gene

Chromosome:
10
Start:
47,501,854 bp from pter
End:
47,523,638 bp from pter
Size:
21,785 bases
Orientation:
Minus strand

Genomic View for AGAP9 Gene

Genes around AGAP9 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
AGAP9 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for AGAP9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for AGAP9 Gene

Proteins for AGAP9 Gene

  • Protein details for AGAP9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5VTM2-AGAP9_HUMAN
    Recommended name:
    Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 9
    Protein Accession:
    Q5VTM2
    Secondary Accessions:
    • D3YTF3

    Protein attributes for AGAP9 Gene

    Size:
    703 amino acids
    Molecular mass:
    77972 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • Encoded by one of the numerous copies of centaurin gamma-like genes clustered in the q11 region of chromosome 10.
    SequenceCaution:
    • Sequence=CAH72201.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for AGAP9 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for AGAP9 Gene

Proteomics data for AGAP9 Gene at MOPED

Post-translational modifications for AGAP9 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for AGAP9 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for AGAP9 Gene

Domains & Families for AGAP9 Gene

Protein Domains for AGAP9 Gene

Suggested Antigen Peptide Sequences for AGAP9 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q5VTM2

UniProtKB/Swiss-Prot:

AGAP9_HUMAN :
  • Contains 1 Arf-GAP domain.
  • Belongs to the centaurin gamma-like family.
  • Contains 1 ANK repeat.
Domain:
  • Contains 1 Arf-GAP domain.
  • Contains 1 PH domain.
Family:
  • Belongs to the centaurin gamma-like family.
Similarity:
  • Contains 1 ANK repeat.
genes like me logo Genes that share domains with AGAP9: view

Function for AGAP9 Gene

Molecular function for AGAP9 Gene

UniProtKB/Swiss-Prot Function:
Putative GTPase-activating protein.

Phenotypes for AGAP9 Gene

genes like me logo Genes that share phenotypes with AGAP9: view

Animal Model Products

CRISPR Products

miRNA for AGAP9 Gene

miRTarBase miRNAs that target AGAP9

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for AGAP9 Gene

Localization for AGAP9 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for AGAP9 Gene

Pathways & Interactions for AGAP9 Gene

SuperPathways for AGAP9 Gene

No Data Available

Interacting Proteins for AGAP9 Gene

Gene Ontology (GO) - Biological Process for AGAP9 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for AGAP9 Gene

Drugs & Compounds for AGAP9 Gene

No Compound Related Data Available

Transcripts for AGAP9 Gene

mRNA/cDNA for AGAP9 Gene

(1) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for AGAP9 Gene

ArfGAP with GTPase domain, ankyrin repeat and PH domain 9:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for AGAP9 Gene

No ASD Table

Relevant External Links for AGAP9 Gene

GeneLoc Exon Structure for
AGAP9
ECgene alternative splicing isoforms for
AGAP9

Expression for AGAP9 Gene

mRNA expression in normal human tissues for AGAP9 Gene

Protein differential expression in normal tissues from HIPED for AGAP9 Gene

This gene is overexpressed in Cerebrospinal fluid (66.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for AGAP9 Gene



SOURCE GeneReport for Unigene cluster for AGAP9 Gene Hs.645346

genes like me logo Genes that share expression patterns with AGAP9: view

Protein tissue co-expression partners for AGAP9 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for AGAP9 Gene

Orthologs for AGAP9 Gene

This gene was present in the common ancestor of animals.

Orthologs for AGAP9 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CTGLF2 35
  • 97.44 (n)
  • 94.71 (a)
-- 36
  • 76 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 58 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 42 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 36
  • 50 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 8 (a)
ManyToMany
-- 36
  • 56 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii agap1 36
  • 42 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta cenG1A 36
  • 23 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea cnt-2 36
  • 18 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 31 (a)
OneToMany
Species with no ortholog for AGAP9:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for AGAP9 Gene

ENSEMBL:
Gene Tree for AGAP9 (if available)
TreeFam:
Gene Tree for AGAP9 (if available)

Paralogs for AGAP9 Gene

(17) SIMAP similar genes for AGAP9 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with AGAP9: view

Variants for AGAP9 Gene

Structural Variations from Database of Genomic Variants (DGV) for AGAP9 Gene

Variant ID Type Subtype PubMed ID
dgv252e1 CNV Complex 17122850
esv2750898 CNV Loss 17911159
dgv254e1 CNV Complex 17122850
nsv516485 CNV Gain+Loss 19592680
nsv895114 CNV Gain 21882294
esv34875 CNV Gain 17911159
nsv510991 OTHER Complex 20534489
dgv256e1 CNV Complex 17122850
dgv257e1 CNV Complex 17122850
esv22204 CNV Gain+Loss 19812545
dgv258e1 CNV Complex 17122850
nsv8636 CNV Gain+Loss 18304495
nsv436102 CNV Deletion 17901297
nsv7203 OTHER Inversion 18451855
esv2736152 CNV Deletion 23290073
dgv656n71 CNV Gain 21882294
esv2736163 CNV Deletion 23290073
dgv259e1 CNV Complex 17122850
dgv260e1 CNV Complex 17122850
nsv895135 CNV Loss 21882294
dgv660n71 CNV Gain 21882294
dgv661n71 CNV Gain 21882294
dgv262e1 CNV Complex 17122850
dgv23e55 CNV Loss 17911159
dgv24e55 CNV Gain 17911159
nsv821667 CNV Gain 15273396
nsv470934 CNV Gain 18288195
nsv818758 CNV Gain 17921354
dgv665n71 CNV Gain 21882294
dgv264e1 CNV Complex 17122850
nsv831853 CNV Gain 17160897
dgv666n71 CNV Gain 21882294
nsv831854 CNV Gain 17160897
esv2663732 CNV Deletion 23128226
dgv667n71 CNV Loss 21882294
dgv668n71 CNV Gain 21882294
nsv467059 CNV Gain 19166990
esv21870 CNV Gain+Loss 19812545
nsv895340 CNV Gain 21882294
nsv831860 CNV Gain 17160897
dgv269e1 CNV Complex 17122850
dgv696n71 CNV Gain 21882294

Relevant External Links for AGAP9 Gene

HapMap Linkage Disequilibrium report
AGAP9

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for AGAP9 Gene

Disorders for AGAP9 Gene

Relevant External Links for AGAP9

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
AGAP9

No disorders were found for AGAP9 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for AGAP9 Gene

Publications for AGAP9 Gene

  1. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 4 67
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for AGAP9 Gene

Sources for AGAP9 Gene

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