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Aliases for AGAP9 Gene

Aliases for AGAP9 Gene

  • ArfGAP With GTPase Domain, Ankyrin Repeat And PH Domain 9 2 3 5
  • Centaurin-Gamma-Like Family Member 6 3 4
  • CTGLF6 3 4
  • AGAP-9 3 4
  • Arf-GAP With GTPase, ANK Repeat And PH Domain-Containing Protein 9 3
  • Centaurin, Gamma-Like Family, Member 6 2
  • BA301J7.2 3

External Ids for AGAP9 Gene

Previous HGNC Symbols for AGAP9 Gene

  • CTGLF6

Previous GeneCards Identifiers for AGAP9 Gene

  • GC10P047809
  • GC10P047834
  • GC10P048214
  • GC10P048189

Summaries for AGAP9 Gene

GeneCards Summary for AGAP9 Gene

AGAP9 (ArfGAP With GTPase Domain, Ankyrin Repeat And PH Domain 9) is a Protein Coding gene. GO annotations related to this gene include GTP binding and GTPase activator activity. An important paralog of this gene is AGAP5.

UniProtKB/Swiss-Prot for AGAP9 Gene

  • Putative GTPase-activating protein.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for AGAP9 Gene

Genomics for AGAP9 Gene

Regulatory Elements for AGAP9 Gene

Enhancers for AGAP9 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10G046522 1.4 Ensembl ENCODE 74.5 +998.9 998940 3.6 HDGF ARNT SIN3A YBX1 ZNF2 ZBTB7B ZNF766 ZNF207 ZNF143 FOS PARGP1 AGAP4 AGAP9 BMS1P1 WASHC2C FAM21FP LOC105378289 FAM35BP ANXA8L1 PTPN20
GH10G046555 1.4 Ensembl ENCODE dbSUPER 13.8 +966.9 966949 2.9 HDGF SIN3A GLI4 RAD21 KLF7 EGR2 ZNF202 ZNF654 SP3 ZNF680 BMS1P1 WASHC2C PARGP1 BMS1P2 AGAP9 AGAP10P RHEBP1 GPRIN2 PIR32632
GH10G047420 0.7 ENCODE 22.9 +102.4 102420 1.6 KLF1 JUN FEZF1 ZIC2 RFX5 FOSL1 ZNF121 GATA3 FOS TCF7L2 AGAP9 ZNF488 GDF2 LOC105378292 PIR39362
GH10G048305 1.1 ENCODE 10.5 -783.2 -783229 2.1 MLX CREB3L1 ARNT ARID4B SIN3A DMAP1 ZNF2 SLC30A9 ZNF143 KLF13 AGAP9 MAPK8 ENSG00000279822
GH10G047383 1 ENCODE 10.6 +139.4 139359 1.9 HDGF HNRNPUL1 ATF1 SIN3A ZNF2 ZNF48 GLIS2 ZNF263 SP3 MXD4 AGAP9 BMS1P1 LOC105378289 ZNF488 RBP3
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around AGAP9 on UCSC Golden Path with GeneCards custom track

Genomic Location for AGAP9 Gene

47,501,854 bp from pter
47,523,638 bp from pter
21,785 bases
Minus strand

Genomic View for AGAP9 Gene

Genes around AGAP9 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
AGAP9 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for AGAP9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for AGAP9 Gene

Proteins for AGAP9 Gene

  • Protein details for AGAP9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 9
    Protein Accession:
    Secondary Accessions:
    • D3YTF3

    Protein attributes for AGAP9 Gene

    703 amino acids
    Molecular mass:
    77972 Da
    Quaternary structure:
    No Data Available
    • Encoded by one of the numerous copies of centaurin gamma-like genes clustered in the q11 region of chromosome 10.
    • Sequence=CAH72201.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for AGAP9 Gene


neXtProt entry for AGAP9 Gene

Post-translational modifications for AGAP9 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for AGAP9 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for AGAP9 Gene

Domains & Families for AGAP9 Gene

Protein Domains for AGAP9 Gene

Suggested Antigen Peptide Sequences for AGAP9 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the centaurin gamma-like family.
  • Belongs to the centaurin gamma-like family.
genes like me logo Genes that share domains with AGAP9: view

Function for AGAP9 Gene

Molecular function for AGAP9 Gene

UniProtKB/Swiss-Prot Function:
Putative GTPase-activating protein.

Gene Ontology (GO) - Molecular Function for AGAP9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005096 GTPase activator activity IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with AGAP9: view

Phenotypes for AGAP9 Gene

genes like me logo Genes that share phenotypes with AGAP9: view

Animal Model Products

CRISPR Products

miRNA for AGAP9 Gene

miRTarBase miRNAs that target AGAP9

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for AGAP9 Gene

Localization for AGAP9 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for AGAP9 Gene

Pathways & Interactions for AGAP9 Gene

SuperPathways for AGAP9 Gene

No Data Available

Interacting Proteins for AGAP9 Gene

Selected Interacting proteins: Q5VTM2-AGAP9_HUMAN for AGAP9 Gene via IID

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for AGAP9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0043547 positive regulation of GTPase activity IEA --
genes like me logo Genes that share ontologies with AGAP9: view

No data available for Pathways by source and SIGNOR curated interactions for AGAP9 Gene

Drugs & Compounds for AGAP9 Gene

No Compound Related Data Available

Transcripts for AGAP9 Gene

mRNA/cDNA for AGAP9 Gene

(1) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for AGAP9 Gene

ArfGAP with GTPase domain, ankyrin repeat and PH domain 9:
Representative Sequences:

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for AGAP9 Gene

No ASD Table

Relevant External Links for AGAP9 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for AGAP9 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for AGAP9 Gene

Protein differential expression in normal tissues from HIPED for AGAP9 Gene

This gene is overexpressed in Cerebrospinal fluid (66.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for AGAP9 Gene

Protein tissue co-expression partners for AGAP9 Gene

NURSA nuclear receptor signaling pathways regulating expression of AGAP9 Gene:


SOURCE GeneReport for Unigene cluster for AGAP9 Gene:

genes like me logo Genes that share expression patterns with AGAP9: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for AGAP9 Gene

Orthologs for AGAP9 Gene

This gene was present in the common ancestor of animals.

Orthologs for AGAP9 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia CTGLF2 34
  • 97.44 (n)
-- 35
  • 76 (a)
(Monodelphis domestica)
Mammalia -- 35
  • 58 (a)
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 42 (a)
(Gallus gallus)
Aves -- 35
  • 50 (a)
(Anolis carolinensis)
Reptilia -- 35
  • 56 (a)
-- 35
  • 8 (a)
(Danio rerio)
Actinopterygii agap1 35
  • 42 (a)
fruit fly
(Drosophila melanogaster)
Insecta cenG1A 35
  • 23 (a)
(Caenorhabditis elegans)
Secernentea cnt-2 35
  • 18 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 31 (a)
Species where no ortholog for AGAP9 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for AGAP9 Gene

Gene Tree for AGAP9 (if available)
Gene Tree for AGAP9 (if available)

Paralogs for AGAP9 Gene

(17) SIMAP similar genes for AGAP9 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with AGAP9: view

Variants for AGAP9 Gene

Sequence variations from dbSNP and Humsavar for AGAP9 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs1047435 -- 47,502,436(-) AGGAA(C/T)GGTGG intron-variant, reference, missense
rs1047447 -- 47,502,343(-) CCACC(A/G)CTGAT intron-variant, reference, missense
rs1047466 -- 47,502,248(-) ACGGC(A/G)CTCCA intron-variant, reference, synonymous-codon
rs1047615 -- 47,501,918(-) TTTTC(C/T)GACCA intron-variant, utr-variant-3-prime
rs1047621 -- 47,501,913(-) TGACC(A/G)TAAGA intron-variant, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for AGAP9 Gene

Variant ID Type Subtype PubMed ID
dgv137e199 CNV deletion 23128226
nsv1068309 CNV deletion 25765185
nsv1118173 CNV deletion 24896259
nsv982761 CNV duplication 23825009

Relevant External Links for AGAP9 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for AGAP9 Gene

Disorders for AGAP9 Gene

Relevant External Links for AGAP9

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for AGAP9 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for AGAP9 Gene

Publications for AGAP9 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 64
  2. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for AGAP9 Gene

Sources for AGAP9 Gene

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